Motif ID: Trp73

Z-value: 0.596


Transcription factors associated with Trp73:

Gene SymbolEntrez IDGene Name
Trp73 ENSMUSG00000029026.10 Trp73

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Trp73mm10_v2_chr4_-_154097105_1540971730.515.9e-05Click!


Activity profile for motif Trp73.

activity profile for motif Trp73


Sorted Z-values histogram for motif Trp73

Sorted Z-values for motif Trp73



Network of associatons between targets according to the STRING database.



First level regulatory network of Trp73

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_48261427 7.760 ENSMUST00000021810.1
Id4
inhibitor of DNA binding 4
chr7_-_116038734 5.072 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr1_+_153665274 4.302 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr12_-_45074112 3.745 ENSMUST00000120531.1
ENSMUST00000143376.1
Stxbp6

syntaxin binding protein 6 (amisyn)

chr16_-_17125106 3.688 ENSMUST00000093336.6
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chrX_+_10717390 3.665 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr7_-_141443314 3.623 ENSMUST00000106005.2
Lrdd
leucine-rich and death domain containing
chr15_+_99055164 3.404 ENSMUST00000047104.7
ENSMUST00000024249.3
Prph

peripherin

chr1_+_72824482 3.366 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr17_+_29090969 3.345 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr12_-_45074457 3.296 ENSMUST00000053768.6
Stxbp6
syntaxin binding protein 6 (amisyn)
chr7_-_116308241 3.175 ENSMUST00000183057.1
ENSMUST00000182487.1
ENSMUST00000181998.1
Plekha7


pleckstrin homology domain containing, family A member 7


chr1_-_5070281 3.141 ENSMUST00000147158.1
ENSMUST00000118000.1
Rgs20

regulator of G-protein signaling 20

chrX_+_10717451 3.126 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr1_+_135729147 3.121 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr3_+_159839729 2.913 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr4_+_62583568 2.192 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chrX_-_109013389 1.857 ENSMUST00000033597.8
Hmgn5
high-mobility group nucleosome binding domain 5
chr4_+_101068983 1.588 ENSMUST00000038463.8
ENSMUST00000106955.1
Raver2

ribonucleoprotein, PTB-binding 2

chr2_-_164857671 1.543 ENSMUST00000059954.7
Pltp
phospholipid transfer protein
chr2_-_164857542 1.524 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr19_+_41911851 1.388 ENSMUST00000011896.6
Pgam1
phosphoglycerate mutase 1
chr15_+_76696725 1.385 ENSMUST00000023203.4
Gpt
glutamic pyruvic transaminase, soluble
chr11_-_69948145 1.346 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr4_+_129820198 1.338 ENSMUST00000030578.7
Ptp4a2
protein tyrosine phosphatase 4a2
chr9_-_67760208 1.298 ENSMUST00000068526.5
M5C1000I18Rik
RIKEN cDNA M5C1000I18 gene
chr11_-_102230091 1.187 ENSMUST00000008999.5
Hdac5
histone deacetylase 5
chr8_-_70659645 1.182 ENSMUST00000070173.7
Pgpep1
pyroglutamyl-peptidase I
chrX_-_10216918 1.151 ENSMUST00000072393.2
ENSMUST00000044598.6
ENSMUST00000073392.4
ENSMUST00000115533.1
ENSMUST00000115532.1
Rpgr




retinitis pigmentosa GTPase regulator




chr11_-_102230127 1.122 ENSMUST00000107150.1
ENSMUST00000156337.1
ENSMUST00000107151.2
ENSMUST00000107152.2
Hdac5



histone deacetylase 5



chr3_+_14641722 1.077 ENSMUST00000029071.8
Car13
carbonic anhydrase 13
chr18_+_56432116 1.069 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr12_+_109747903 1.062 ENSMUST00000183084.1
ENSMUST00000182300.1
Mirg

miRNA containing gene

chr10_+_110745433 1.050 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2f7



E2F transcription factor 7



chr4_-_11386757 1.035 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chr19_-_50030735 1.031 ENSMUST00000071866.1
Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr7_-_5014645 0.965 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chr2_+_34772089 0.945 ENSMUST00000028222.6
ENSMUST00000100171.2
Hspa5

heat shock protein 5

chr9_-_109082372 0.934 ENSMUST00000167504.1
Tma7
translational machinery associated 7 homolog (S. cerevisiae)
chr2_+_150909565 0.913 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr10_+_41810528 0.869 ENSMUST00000099931.3
Sesn1
sestrin 1
chr3_+_89245952 0.848 ENSMUST00000040888.5
Krtcap2
keratinocyte associated protein 2
chr11_+_69913888 0.792 ENSMUST00000072581.2
ENSMUST00000116358.1
Gps2

G protein pathway suppressor 2

chr7_+_140881898 0.767 ENSMUST00000026560.7
Psmd13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr4_-_45489794 0.750 ENSMUST00000146236.1
Shb
src homology 2 domain-containing transforming protein B
chr14_+_53665912 0.716 ENSMUST00000181768.1
Trav3-3
T cell receptor alpha variable 3-3
chr11_+_60931998 0.679 ENSMUST00000019076.3
Map2k3
mitogen-activated protein kinase kinase 3
chr19_+_46304709 0.622 ENSMUST00000073116.5
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr11_+_98026918 0.566 ENSMUST00000017548.6
Rpl19
ribosomal protein L19
chr7_-_65371210 0.556 ENSMUST00000102592.3
Tjp1
tight junction protein 1
chr17_+_28232723 0.546 ENSMUST00000002320.8
Ppard
peroxisome proliferator activator receptor delta
chr7_+_140882430 0.542 ENSMUST00000164681.1
ENSMUST00000163610.1
Psmd13

proteasome (prosome, macropain) 26S subunit, non-ATPase, 13

chr3_-_107931579 0.535 ENSMUST00000133947.2
ENSMUST00000124215.1
ENSMUST00000106688.1
ENSMUST00000106687.2
Gstm7



glutathione S-transferase, mu 7



chr14_-_52104015 0.522 ENSMUST00000111610.4
ENSMUST00000164655.1
Hnrnpc

heterogeneous nuclear ribonucleoprotein C

chr2_-_180920925 0.516 ENSMUST00000037299.8
ENSMUST00000108876.2
Ythdf1

YTH domain family 1

chr3_-_89402650 0.465 ENSMUST00000168325.1
ENSMUST00000057431.5
Lenep

lens epithelial protein

chr1_-_55088024 0.460 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr10_-_105841323 0.438 ENSMUST00000046638.9
Mettl25
methyltransferase like 25
chr2_-_90904827 0.387 ENSMUST00000005647.3
Ndufs3
NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr14_-_73325773 0.381 ENSMUST00000022701.6
Rb1
retinoblastoma 1
chr1_+_55088132 0.315 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chr5_+_43233928 0.315 ENSMUST00000114066.1
ENSMUST00000114065.1
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chr6_+_29398920 0.294 ENSMUST00000181464.1
ENSMUST00000180829.1
Ccdc136

coiled-coil domain containing 136

chr11_+_114851507 0.288 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr1_-_170215380 0.240 ENSMUST00000027979.7
ENSMUST00000123399.1
Uhmk1

U2AF homology motif (UHM) kinase 1

chr10_+_127642975 0.223 ENSMUST00000092074.5
ENSMUST00000120279.1
Stat6

signal transducer and activator of transcription 6

chr1_-_12991109 0.188 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr10_+_105841064 0.113 ENSMUST00000020049.8
Ccdc59
coiled-coil domain containing 59
chr15_+_84232030 0.111 ENSMUST00000023072.6
Parvb
parvin, beta
chr11_-_103344651 0.077 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr10_-_127311740 0.076 ENSMUST00000037290.5
ENSMUST00000171564.1
Mars

methionine-tRNA synthetase

chr10_-_67912620 0.063 ENSMUST00000064656.7
Zfp365
zinc finger protein 365
chr15_-_98607611 0.035 ENSMUST00000096224.4
Adcy6
adenylate cyclase 6
chr9_-_65885024 0.020 ENSMUST00000122410.1
ENSMUST00000117083.1
Trip4

thyroid hormone receptor interactor 4

chr4_+_74251928 0.011 ENSMUST00000030102.5
Kdm4c
lysine (K)-specific demethylase 4C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.8 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.0 2.9 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.9 7.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.8 3.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.5 3.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 1.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.5 5.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.4 6.8 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.4 3.3 GO:0071493 cellular response to UV-B(GO:0071493)
0.4 1.4 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.3 0.9 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.3 4.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 2.3 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.2 3.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.5 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.9 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 3.4 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.7 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 1.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.8 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.1 0.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 1.3 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.1 0.2 GO:0048289 interleukin-4-mediated signaling pathway(GO:0035771) isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.1 0.2 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.6 GO:0002467 germinal center formation(GO:0002467)
0.0 0.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.8 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.0 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 2.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 0.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.7 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 5.4 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0044299 C-fiber(GO:0044299)
1.1 3.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 7.0 GO:0000145 exocyst(GO:0000145)
0.3 0.9 GO:0000811 GINS complex(GO:0000811)
0.3 3.2 GO:0005915 zonula adherens(GO:0005915)
0.3 2.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 3.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 3.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.9 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 6.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 5.9 GO:0005874 microtubule(GO:0005874)
0.0 3.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.7 GO:0043209 myelin sheath(GO:0043209)
0.0 2.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.8 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.5 1.4 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 3.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 7.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 1.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.3 2.3 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.3 2.9 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.3 3.2 GO:0070097 delta-catenin binding(GO:0070097)
0.2 0.5 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.2 1.2 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.9 GO:0070728 leucine binding(GO:0070728)
0.1 4.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.4 GO:0008483 transaminase activity(GO:0008483)
0.1 0.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.9 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 1.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 7.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 5.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 5.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 3.1 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.1 2.0 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 3.2 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 2.3 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.2 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.5 PID_TELOMERASE_PATHWAY Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 3.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.3 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.9 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.6 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.9 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 1.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 7.5 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 2.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.3 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)