---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_139543889	58.673	ENSMUST00000174792.1 ENSMUST00000031523.8	Uncx	UNC homeobox
chr6_-_23248264	35.200	ENSMUST00000031709.5	Fezf1	Fez family zinc finger 1
chr2_-_168767136	12.601	ENSMUST00000029061.5 ENSMUST00000103074.1	Sall4	sal-like 4 (Drosophila)
chr10_+_73821857	8.507	ENSMUST00000177128.1 ENSMUST00000064562.7 ENSMUST00000129404.2 ENSMUST00000105426.3 ENSMUST00000131321.2 ENSMUST00000126920.2 ENSMUST00000147189.2 ENSMUST00000105424.3 ENSMUST00000092420.6 ENSMUST00000105429.3 ENSMUST00000131724.2 ENSMUST00000152655.2 ENSMUST00000151116.2 ENSMUST00000155701.2 ENSMUST00000152819.2 ENSMUST00000125517.2 ENSMUST00000124046.1 ENSMUST00000149977.2 ENSMUST00000146682.1 ENSMUST00000177107.1	Pcdh15	protocadherin 15
chr2_-_168767029	7.869	ENSMUST00000075044.3	Sall4	sal-like 4 (Drosophila)
chr17_-_70853482	7.747	ENSMUST00000118283.1	Tgif1	TGFB-induced factor homeobox 1
chr12_+_38780284	7.644	ENSMUST00000162563.1 ENSMUST00000161164.1 ENSMUST00000160996.1	Etv1	ets variant gene 1
chr7_-_49636847	7.476	ENSMUST00000032717.6	Dbx1	developing brain homeobox 1
chr12_+_38780817	7.339	ENSMUST00000160856.1	Etv1	ets variant gene 1
chr3_+_159839729	7.267	ENSMUST00000068952.5	Wls	wntless homolog (Drosophila)
chr4_+_8690399	7.148	ENSMUST00000127476.1	Chd7	chromodomain helicase DNA binding protein 7
chr3_-_116253467	6.496	ENSMUST00000090473.5	Gpr88	G-protein coupled receptor 88
chrX_-_60893430	6.299	ENSMUST00000135107.2	Sox3	SRY-box containing gene 3
chr3_+_55782500	6.176	ENSMUST00000075422.4	Mab21l1	mab-21-like 1 (C. elegans)
chr4_+_62583568	6.033	ENSMUST00000098031.3	Rgs3	regulator of G-protein signaling 3
chr3_-_79841729	5.803	ENSMUST00000168038.1	Tmem144	transmembrane protein 144
chr9_-_79977782	5.416	ENSMUST00000093811.4	Filip1	filamin A interacting protein 1
chr17_+_43952999	5.289	ENSMUST00000177857.1	Rcan2	regulator of calcineurin 2
chr10_-_6980376	4.887	ENSMUST00000105617.1	Ipcef1	interaction protein for cytohesin exchange factors 1
chr8_-_61902669	4.755	ENSMUST00000121785.1 ENSMUST00000034057.7	Palld	palladin, cytoskeletal associated protein
chr3_-_154328634	4.735	ENSMUST00000167744.1	Lhx8	LIM homeobox protein 8
chr14_-_48662740	4.677	ENSMUST00000122009.1	Otx2	orthodenticle homolog 2 (Drosophila)
chr7_-_116031047	4.529	ENSMUST00000106612.1	Sox6	SRY-box containing gene 6
chr3_-_88410295	4.329	ENSMUST00000056370.7	Pmf1	polyamine-modulated factor 1
chr18_+_82914632	4.144	ENSMUST00000071233.6	Zfp516	zinc finger protein 516
chr1_+_109983737	4.013	ENSMUST00000172005.1	Cdh7	cadherin 7, type 2
chr7_-_115846080	4.008	ENSMUST00000166207.1	Sox6	SRY-box containing gene 6
chr8_-_57653023	3.762	ENSMUST00000034021.5	Galnt7	UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr8_-_45382198	3.685	ENSMUST00000093526.6	Fam149a	family with sequence similarity 149, member A
chr12_+_38781093	3.624	ENSMUST00000161513.1	Etv1	ets variant gene 1
chr11_-_102579461	3.482	ENSMUST00000107081.1	Gm11627	predicted gene 11627
chr12_-_56535047	3.376	ENSMUST00000178477.2	Nkx2-1	NK2 homeobox 1
chr5_-_98566762	3.366	ENSMUST00000086912.4	1700010H22Rik	RIKEN cDNA 1700010H22 gene
chr6_-_147264124	3.037	ENSMUST00000052296.6	Pthlh	parathyroid hormone-like peptide
chr11_-_102579071	2.991	ENSMUST00000107080.1	Gm11627	predicted gene 11627
chr4_-_132510493	2.946	ENSMUST00000030724.8	Sesn2	sestrin 2
chr15_+_25773985	2.609	ENSMUST00000125667.1	Myo10	myosin X
chr9_+_75775355	2.566	ENSMUST00000012281.7	Bmp5	bone morphogenetic protein 5
chr9_+_119063429	2.537	ENSMUST00000141185.1 ENSMUST00000126251.1 ENSMUST00000136561.1	Vill	villin-like
chrM_+_7005	2.502	ENSMUST00000082405.1	mt-Co2	mitochondrially encoded cytochrome c oxidase II
chr12_-_31713873	2.253	ENSMUST00000057783.4 ENSMUST00000174480.2 ENSMUST00000176710.1	Gpr22	G protein-coupled receptor 22
chr5_-_138187177	2.178	ENSMUST00000110937.1 ENSMUST00000139276.1 ENSMUST00000048698.7 ENSMUST00000123415.1	Taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_-_129261394	2.139	ENSMUST00000145261.1	C77080	expressed sequence C77080
chr14_-_12345847	2.118	ENSMUST00000022262.4	Fezf2	Fez family zinc finger 2
chr4_-_110292719	2.007	ENSMUST00000106601.1	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_-_121235689	1.987	ENSMUST00000142400.1	Trp53bp1	transformation related protein 53 binding protein 1
chr9_-_106891401	1.936	ENSMUST00000069036.7	Manf	mesencephalic astrocyte-derived neurotrophic factor
chr1_-_172027269	1.916	ENSMUST00000027837.6 ENSMUST00000111264.1	Vangl2	vang-like 2 (van gogh, Drosophila)
chr5_+_138187485	1.772	ENSMUST00000110934.2	Cnpy4	canopy 4 homolog (zebrafish)
chr17_-_70998010	1.760	ENSMUST00000024846.6	Myl12a	myosin, light chain 12A, regulatory, non-sarcomeric
chr10_+_128337761	1.727	ENSMUST00000005826.7	Cs	citrate synthase
chr2_-_79456750	1.683	ENSMUST00000041099.4	Neurod1	neurogenic differentiation 1
chr17_-_35697971	1.658	ENSMUST00000146472.1	Ddr1	discoidin domain receptor family, member 1
chr1_-_78968079	1.651	ENSMUST00000049117.5	Gm5830	predicted pseudogene 5830
chr13_-_100616911	1.649	ENSMUST00000168772.1 ENSMUST00000163163.1 ENSMUST00000022137.7	Marveld2	MARVEL (membrane-associating) domain containing 2
chr7_+_144838590	1.626	ENSMUST00000105898.1	Fgf3	fibroblast growth factor 3
chr4_-_110286581	1.622	ENSMUST00000138972.1	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr11_-_102185239	1.607	ENSMUST00000021297.5	Lsm12	LSM12 homolog (S. cerevisiae)
chr14_-_122451109	1.604	ENSMUST00000081580.2	Gm5089	predicted gene 5089
chr4_-_83285141	1.594	ENSMUST00000150522.1	Ttc39b	tetratricopeptide repeat domain 39B
chr1_+_10993452	1.588	ENSMUST00000027056.5	Prex2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr4_-_45532470	1.535	ENSMUST00000147448.1	Shb	src homology 2 domain-containing transforming protein B
chr11_+_62077018	1.461	ENSMUST00000092415.5	Specc1	sperm antigen with calponin homology and coiled-coil domains 1
chr13_-_102906046	1.385	ENSMUST00000171791.1	Mast4	microtubule associated serine/threonine kinase family member 4
chr11_+_94327984	1.384	ENSMUST00000107818.2 ENSMUST00000051221.6	Ankrd40	ankyrin repeat domain 40
chr6_+_73248382	1.306	ENSMUST00000064740.6	Suclg1	succinate-CoA ligase, GDP-forming, alpha subunit
chr18_-_44662251	1.275	ENSMUST00000164666.1	Mcc	mutated in colorectal cancers
chr13_-_102905740	1.257	ENSMUST00000167462.1	Mast4	microtubule associated serine/threonine kinase family member 4
chr3_+_5218546	1.240	ENSMUST00000026284.6	Zfhx4	zinc finger homeodomain 4
chr1_-_172027251	1.137	ENSMUST00000138714.1	Vangl2	vang-like 2 (van gogh, Drosophila)
chr4_-_41464816	1.118	ENSMUST00000108055.2 ENSMUST00000154535.1 ENSMUST00000030148.5	Kif24	kinesin family member 24
chr12_+_108605757	1.051	ENSMUST00000109854.2	Evl	Ena-vasodilator stimulated phosphoprotein
chr1_-_84839304	0.928	ENSMUST00000027421.6	Trip12	thyroid hormone receptor interactor 12
chrX_+_107255878	0.890	ENSMUST00000101294.2 ENSMUST00000118820.1 ENSMUST00000120971.1	Gpr174	G protein-coupled receptor 174
chr5_+_27261916	0.867	ENSMUST00000101471.3	Dpp6	dipeptidylpeptidase 6
chr1_-_79440039	0.863	ENSMUST00000049972.4	Scg2	secretogranin II
chr11_+_60537978	0.824	ENSMUST00000044250.3	Alkbh5	alkB, alkylation repair homolog 5 (E. coli)
chr8_-_84846860	0.790	ENSMUST00000003912.6	Calr	calreticulin
chr12_+_55598917	0.768	ENSMUST00000051857.3	Insm2	insulinoma-associated 2
chr7_-_5014645	0.723	ENSMUST00000165320.1	Fiz1	Flt3 interacting zinc finger protein 1
chr1_-_72874877	0.715	ENSMUST00000027377.8	Igfbp5	insulin-like growth factor binding protein 5
chr1_+_132298606	0.683	ENSMUST00000046071.4	Klhdc8a	kelch domain containing 8A
chr17_+_17402672	0.663	ENSMUST00000115576.2	Lix1	limb expression 1 homolog (chicken)
chr3_+_76593550	0.636	ENSMUST00000162471.1	Fstl5	follistatin-like 5
chr18_-_75697639	0.629	ENSMUST00000165559.1	Ctif	CBP80/20-dependent translation initiation factor
chr2_+_9882622	0.626	ENSMUST00000114919.1	4930412O13Rik	RIKEN cDNA 4930412O13 gene
chr1_-_182282738	0.592	ENSMUST00000035295.5	Degs1	degenerative spermatocyte homolog 1 (Drosophila)
chr12_+_52699297	0.585	ENSMUST00000095737.3	Akap6	A kinase (PRKA) anchor protein 6
chr12_+_109545390	0.557	ENSMUST00000146701.1	Meg3	maternally expressed 3
chr1_-_190170671	0.535	ENSMUST00000175916.1	Prox1	prospero-related homeobox 1
chr5_-_137531952	0.533	ENSMUST00000140139.1	Gnb2	guanine nucleotide binding protein (G protein), beta 2
chr3_+_5218516	0.525	ENSMUST00000175866.1	Zfhx4	zinc finger homeodomain 4
chr9_-_21312255	0.495	ENSMUST00000115433.3 ENSMUST00000003397.7	Ap1m2	adaptor protein complex AP-1, mu 2 subunit
chr16_+_34690548	0.485	ENSMUST00000023532.6	Ccdc14	coiled-coil domain containing 14
chr7_+_123123870	0.471	ENSMUST00000094053.5	Tnrc6a	trinucleotide repeat containing 6a
chr9_+_94669876	0.463	ENSMUST00000033463.9	Slc9a9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr2_-_59948155	0.432	ENSMUST00000153136.1	Baz2b	bromodomain adjacent to zinc finger domain, 2B
chr9_-_71163224	0.431	ENSMUST00000074465.2	Aqp9	aquaporin 9
chr2_+_71528657	0.412	ENSMUST00000126400.1	Dlx1	distal-less homeobox 1
chrX_+_140956892	0.404	ENSMUST00000112971.1	Atg4a	autophagy related 4A, cysteine peptidase
chr3_+_122274371	0.400	ENSMUST00000035776.8	Dnttip2	deoxynucleotidyltransferase, terminal, interacting protein 2
chr11_-_33203588	0.379	ENSMUST00000037746.6	Tlx3	T cell leukemia, homeobox 3
chr2_-_71055534	0.331	ENSMUST00000090849.5 ENSMUST00000100037.2 ENSMUST00000112186.2	Mettl8	methyltransferase like 8
chr4_+_110397661	0.319	ENSMUST00000106589.2 ENSMUST00000106587.2 ENSMUST00000106591.1 ENSMUST00000106592.1	Agbl4	ATP/GTP binding protein-like 4
chr3_+_5218589	0.316	ENSMUST00000177488.1	Zfhx4	zinc finger homeodomain 4
chr18_-_80986578	0.277	ENSMUST00000057950.7	Sall3	sal-like 3 (Drosophila)
chr3_+_122419772	0.275	ENSMUST00000029766.4	Bcar3	breast cancer anti-estrogen resistance 3
chr12_-_56613270	0.272	ENSMUST00000072631.5	Nkx2-9	NK2 homeobox 9
chr10_-_53647080	0.259	ENSMUST00000169866.1	Fam184a	family with sequence similarity 184, member A
chr6_+_108065035	0.203	ENSMUST00000049246.6	Setmar	SET domain without mariner transposase fusion
chr2_+_109917639	0.195	ENSMUST00000046548.7 ENSMUST00000111037.2	Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4
chr4_+_110397764	0.168	ENSMUST00000097920.2 ENSMUST00000080744.6	Agbl4	ATP/GTP binding protein-like 4
chr2_-_36136773	0.157	ENSMUST00000028251.3	Rbm18	RNA binding motif protein 18
chr7_-_73541738	0.121	ENSMUST00000169922.2	Chd2	chromodomain helicase DNA binding protein 2
chr18_-_66022580	0.115	ENSMUST00000143990.1	Lman1	lectin, mannose-binding, 1
chr16_-_45724600	0.090	ENSMUST00000096057.4	Tagln3	transgelin 3
chr4_+_99955715	0.088	ENSMUST00000102783.4	Pgm2	phosphoglucomutase 2
chr1_+_87183310	0.049	ENSMUST00000044533.8	Prss56	protease, serine 56
chr10_+_127420867	0.046	ENSMUST00000064793.6	R3hdm2	R3H domain containing 2
chr1_+_66468364	0.038	ENSMUST00000061620.9	Unc80	unc-80 homolog (C. elegans)
chr9_-_65885024	0.034	ENSMUST00000122410.1 ENSMUST00000117083.1	Trip4	thyroid hormone receptor interactor 4

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.3	58.7	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
6.2	37.3	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
2.4	7.3	GO:0061357	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
2.4	7.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.7	18.6	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.6	6.5	GO:0061743	motor learning(GO:0061743)
1.2	4.7	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.1	20.5	GO:0001833	inner cell mass cell proliferation(GO:0001833)
1.1	3.4	GO:0021759	globus pallidus development(GO:0021759)
1.1	8.5	GO:0050957	equilibrioception(GO:0050957)
1.0	3.1	GO:0060489	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.0	2.9	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.8	8.5	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.6	1.9	GO:0002014	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.6	2.6	GO:0021502	neural fold elevation formation(GO:0021502)
0.6	1.7	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.5	8.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4	5.8	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.4	7.5	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.3	3.0	GO:0043129	surfactant homeostasis(GO:0043129)
0.3	6.3	GO:0007530	sex determination(GO:0007530)
0.3	0.9	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.3	4.8	GO:0071803	keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.2	4.0	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.2	0.8	GO:0035553	oxidative single-stranded RNA demethylation(GO:0035553)
0.2	0.5	GO:0090425	hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.2	1.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.2	0.9	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.2	1.5	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.1	0.6	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1	1.3	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	1.7	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.4	GO:0061075	cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1	2.0	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	0.5	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.1	0.7	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	1.7	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.1	4.1	GO:0050873	brown fat cell differentiation(GO:0050873)
0.1	0.4	GO:0051697	protein delipidation(GO:0051697)
0.1	3.8	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.1	1.6	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.1	0.2	GO:0072204	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1	0.4	GO:0032782	bile acid secretion(GO:0032782)
0.1	2.5	GO:0051693	actin filament capping(GO:0051693)
0.1	2.7	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.5	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	2.5	GO:0042773	ATP synthesis coupled electron transport(GO:0042773)
0.0	1.6	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	1.6	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.3	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.5	GO:0045974	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	2.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.4	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.6	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.7	GO:0097352	autophagosome maturation(GO:0097352)
0.0	1.3	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	1.8	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.9	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.5	GO:0071539	protein localization to centrosome(GO:0071539)
0.0	0.9	GO:1903078	positive regulation of protein localization to plasma membrane(GO:1903078)
0.0	1.1	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	0.6	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	4.7	GO:0001674	female germ cell nucleus(GO:0001674)
0.8	3.1	GO:0060187	cell pole(GO:0060187)
0.7	4.3	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.3	2.9	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.3	1.6	GO:0061689	paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.2	3.6	GO:0042788	polysomal ribosome(GO:0042788)
0.2	1.3	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2	8.5	GO:0032420	stereocilium(GO:0032420)
0.2	0.7	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.2	2.5	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.2	7.3	GO:0032590	dendrite membrane(GO:0032590)
0.1	20.5	GO:0000792	heterochromatin(GO:0000792)
0.1	2.2	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.1	4.8	GO:0002102	podosome(GO:0002102)
0.1	0.8	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.1	1.8	GO:0016460	myosin II complex(GO:0016460)
0.1	2.6	GO:0016459	myosin complex(GO:0016459)
0.1	2.0	GO:0035861	site of double-strand break(GO:0035861)
0.1	0.9	GO:0031045	dense core granule(GO:0031045)
0.1	0.5	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.6	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.5	GO:0034451	centriolar satellite(GO:0034451)
0.0	1.1	GO:0005871	kinesin complex(GO:0005871)
0.0	10.7	GO:0005667	transcription factor complex(GO:0005667)
0.0	142.0	GO:0005634	nucleus(GO:0005634)
0.0	0.5	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0033655	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	7.3	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.7	4.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.5	2.9	GO:0070728	leucine binding(GO:0070728)
0.4	1.3	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.4	4.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.4	7.7	GO:0070410	co-SMAD binding(GO:0070410)
0.3	2.0	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.3	3.0	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.3	1.7	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3	3.4	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3	2.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.3	2.6	GO:0070700	BMP receptor binding(GO:0070700)
0.2	3.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2	0.8	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.2	7.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	37.4	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2	0.6	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.2	6.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.2	1.7	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	6.2	GO:0015144	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1	2.5	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	116.1	GO:0043565	sequence-specific DNA binding(GO:0043565)
0.1	3.6	GO:0017091	AU-rich element binding(GO:0017091)
0.1	0.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	1.1	GO:0005522	profilin binding(GO:0005522)
0.1	10.2	GO:0003774	motor activity(GO:0003774)
0.1	0.9	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	9.1	GO:0047485	protein N-terminus binding(GO:0047485)
0.1	0.5	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.1	0.9	GO:0045125	bioactive lipid receptor activity(GO:0045125)
0.1	1.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	6.2	GO:0016779	nucleotidyltransferase activity(GO:0016779)
0.0	0.8	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.3	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	1.8	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	2.6	GO:0051015	actin filament binding(GO:0051015)
0.0	0.9	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.7	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	2.2	GO:0000287	magnesium ion binding(GO:0000287)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	18.6	PID_P38_MK2_PATHWAY	p38 signaling mediated by MAPKAP kinases
0.2	17.6	PID_BETA_CATENIN_NUC_PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.2	7.1	PID_WNT_NONCANONICAL_PATHWAY	Noncanonical Wnt signaling pathway
0.2	6.0	PID_EPHRINB_REV_PATHWAY	Ephrin B reverse signaling
0.1	4.9	SA_PTEN_PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	3.0	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	4.0	PID_TCR_CALCIUM_PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	7.7	PID_AR_PATHWAY	Coregulation of Androgen receptor activity
0.1	1.5	PID_PDGFRA_PATHWAY	PDGFR-alpha signaling pathway
0.1	3.4	PID_HNF3B_PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	2.6	PID_NETRIN_PATHWAY	Netrin-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	7.7	REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	3.0	REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	4.0	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	3.8	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	0.8	REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	1.7	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	0.4	REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	1.1	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES	Genes involved in Generation of second messenger molecules
0.0	2.6	REACTOME_NETRIN1_SIGNALING	Genes involved in Netrin-1 signaling
0.0	2.2	REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.7	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	4.3	REACTOME_MITOTIC_PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	3.3	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.5	REACTOME_REGULATORY_RNA_PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.5	REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.6	REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis

---