ISMARA results: Zbtb3

Motif ID: Zbtb3

Z-value: 0.705

Transcription factors associated with Zbtb3:

Gene Symbol	Entrez ID	Gene Name
Zbtb3	ENSMUSG00000071661.6	Zbtb3

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Zbtb3	mm10_v2_chr19_+_8802486_8802530	0.40	2.5e-03	Click!

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_+_10272572	4.866	ENSMUST00000042103.8	Myo16	myosin XVI
chr16_+_20589471	4.045	ENSMUST00000100074.3 ENSMUST00000096197.4	Vwa5b2	von Willebrand factor A domain containing 5B2
chr7_-_63212514	2.789	ENSMUST00000032738.5	Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7
chr15_+_98167806	2.747	ENSMUST00000031914.4	AI836003	expressed sequence AI836003
chr9_-_40531362	2.598	ENSMUST00000119373.1	Gramd1b	GRAM domain containing 1B
chr1_-_173367638	2.585	ENSMUST00000005470.4 ENSMUST00000111220.1	Cadm3	cell adhesion molecule 3
chr15_-_72546279	2.456	ENSMUST00000044624.6	Kcnk9	potassium channel, subfamily K, member 9
chr15_-_67113909	2.294	ENSMUST00000092640.5	St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr15_-_66969616	2.022	ENSMUST00000170903.1 ENSMUST00000166420.1 ENSMUST00000005256.6 ENSMUST00000164070.1	Ndrg1	N-myc downstream regulated gene 1
chr11_-_3774706	1.983	ENSMUST00000155197.1	Osbp2	oxysterol binding protein 2
chr5_+_30588078	1.782	ENSMUST00000066295.2	Kcnk3	potassium channel, subfamily K, member 3
chr5_+_37242025	1.768	ENSMUST00000114158.2	Crmp1	collapsin response mediator protein 1
chr16_+_11405648	1.737	ENSMUST00000096273.2	Snx29	sorting nexin 29
chr5_+_141856692	1.735	ENSMUST00000074546.6	Sdk1	sidekick homolog 1 (chicken)
chr11_+_87592145	1.520	ENSMUST00000103179.3 ENSMUST00000092802.5 ENSMUST00000146871.1	Mtmr4	myotubularin related protein 4
chr2_-_172043466	1.496	ENSMUST00000087950.3	Cbln4	cerebellin 4 precursor protein
chr11_-_54028090	1.444	ENSMUST00000020586.6	Slc22a4	solute carrier family 22 (organic cation transporter), member 4
chr10_+_74967164	1.410	ENSMUST00000037813.4	Gnaz	guanine nucleotide binding protein, alpha z subunit
chr14_-_19977249	1.338	ENSMUST00000160013.1	Gng2	guanine nucleotide binding protein (G protein), gamma 2
chr18_+_34247685	1.313	ENSMUST00000066133.6	Apc	adenomatosis polyposis coli
chr11_+_73177083	1.289	ENSMUST00000040687.5	Tax1bp3	Tax1 (human T cell leukemia virus type I) binding protein 3
chr8_-_70439557	1.279	ENSMUST00000076615.5	Crtc1	CREB regulated transcription coactivator 1
chr8_+_64947177	1.274	ENSMUST00000079896.7 ENSMUST00000026595.5	Tmem192	transmembrane protein 192
chr19_-_59076069	1.245	ENSMUST00000047511.7 ENSMUST00000163821.1	4930506M07Rik	RIKEN cDNA 4930506M07 gene
chrX_+_53607987	1.215	ENSMUST00000063384.3 ENSMUST00000169626.1	Cxx1c	CAAX box 1C
chr5_+_76840597	1.200	ENSMUST00000120639.2 ENSMUST00000163347.1 ENSMUST00000121851.1	C530008M17Rik	RIKEN cDNA C530008M17 gene
chr4_-_44167988	1.195	ENSMUST00000143337.1	Rnf38	ring finger protein 38
chr19_-_4175470	1.190	ENSMUST00000167055.1	Carns1	carnosine synthase 1
chr5_-_138996087	1.160	ENSMUST00000110897.1	Pdgfa	platelet derived growth factor, alpha
chr5_-_38159457	1.155	ENSMUST00000031009.4	Nsg1	neuron specific gene family member 1
chr11_-_5741141	1.120	ENSMUST00000140922.1 ENSMUST00000093362.5	Urgcp	upregulator of cell proliferation
chr12_+_64917901	1.111	ENSMUST00000058135.4	Gm527	predicted gene 527
chrX_+_53607918	1.091	ENSMUST00000114827.1	Cxx1c	CAAX box 1C
chr17_-_57031468	1.079	ENSMUST00000007814.8	Khsrp	KH-type splicing regulatory protein
chr14_-_19977040	1.053	ENSMUST00000159028.1	Gng2	guanine nucleotide binding protein (G protein), gamma 2
chr13_+_76579670	1.048	ENSMUST00000126960.1 ENSMUST00000109583.2	Mctp1	multiple C2 domains, transmembrane 1
chr14_-_19977151	0.998	ENSMUST00000055100.7 ENSMUST00000162425.1	Gng2	guanine nucleotide binding protein (G protein), gamma 2
chr13_-_96132568	0.984	ENSMUST00000161263.1	Sv2c	synaptic vesicle glycoprotein 2c
chr9_+_32116040	0.959	ENSMUST00000174641.1	Arhgap32	Rho GTPase activating protein 32
chr17_+_24549950	0.930	ENSMUST00000035565.3	Pkd1	polycystic kidney disease 1 homolog
chr12_-_27160311	0.906	ENSMUST00000182473.1 ENSMUST00000177636.1 ENSMUST00000183238.1	Gm9866	predicted gene 9866
chr17_+_46254017	0.900	ENSMUST00000095262.4	Lrrc73	leucine rich repeat containing 73
chr2_-_25627960	0.875	ENSMUST00000028307.8	Fcna	ficolin A
chr1_-_121332571	0.861	ENSMUST00000071064.6	Insig2	insulin induced gene 2
chr18_+_37307445	0.785	ENSMUST00000056712.2	Pcdhb4	protocadherin beta 4
chr6_-_28421680	0.738	ENSMUST00000090511.3	Gcc1	golgi coiled coil 1
chr10_+_61695503	0.736	ENSMUST00000020284.4	Tysnd1	trypsin domain containing 1
chr18_-_24603464	0.735	ENSMUST00000154205.1	Slc39a6	solute carrier family 39 (metal ion transporter), member 6
chr7_-_103843154	0.730	ENSMUST00000063957.4	Hbb-bh1	hemoglobin Z, beta-like embryonic chain
chr9_+_44499126	0.722	ENSMUST00000074989.5	Bcl9l	B cell CLL/lymphoma 9-like
chr15_-_89128634	0.693	ENSMUST00000082197.5	Hdac10	histone deacetylase 10
chr9_+_19641224	0.669	ENSMUST00000079042.6	Zfp317	zinc finger protein 317
chr11_+_116030304	0.659	ENSMUST00000021116.5 ENSMUST00000106452.1	Unk	unkempt homolog (Drosophila)
chr4_-_44168339	0.655	ENSMUST00000045793.8	Rnf38	ring finger protein 38
chr7_-_114562945	0.627	ENSMUST00000119712.1 ENSMUST00000032908.8	Cyp2r1	cytochrome P450, family 2, subfamily r, polypeptide 1
chr5_-_121521573	0.621	ENSMUST00000100757.4	Adam1a	a disintegrin and metallopeptidase domain 1a
chr11_-_86671169	0.604	ENSMUST00000143991.1	Vmp1	vacuole membrane protein 1
chr7_+_82611777	0.598	ENSMUST00000172784.1	Adamtsl3	ADAMTS-like 3
chr6_+_122819888	0.586	ENSMUST00000003238.7	Foxj2	forkhead box J2
chr18_-_24603791	0.574	ENSMUST00000070726.3	Slc39a6	solute carrier family 39 (metal ion transporter), member 6
chr1_+_133045984	0.573	ENSMUST00000077730.5	Pik3c2b	phosphoinositide-3-kinase, class 2, beta polypeptide
chr9_+_75625707	0.565	ENSMUST00000034702.4	Lysmd2	LysM, putative peptidoglycan-binding, domain containing 2
chr18_-_37178493	0.562	ENSMUST00000181887.1 ENSMUST00000180516.1	Gm10544	predicted gene 10544
chr18_+_24603952	0.558	ENSMUST00000025120.6	Elp2	elongator acetyltransferase complex subunit 2
chr19_-_4334001	0.553	ENSMUST00000176653.1	Kdm2a	lysine (K)-specific demethylase 2A
chr2_+_80617045	0.547	ENSMUST00000028384.4	Dusp19	dual specificity phosphatase 19
chr7_-_35318408	0.537	ENSMUST00000079693.5	Gpatch1	G patch domain containing 1
chr9_-_45984816	0.517	ENSMUST00000172450.1	Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr4_-_44167905	0.516	ENSMUST00000102934.2	Rnf38	ring finger protein 38
chr2_-_151744142	0.509	ENSMUST00000109869.1	Psmf1	proteasome (prosome, macropain) inhibitor subunit 1
chr4_-_150008977	0.508	ENSMUST00000030830.3	H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr2_-_157571270	0.508	ENSMUST00000173378.1	Blcap	bladder cancer associated protein homolog (human)
chr7_+_24507099	0.507	ENSMUST00000177228.1	Zfp428	zinc finger protein 428
chr4_-_129662442	0.498	ENSMUST00000003828.4	Kpna6	karyopherin (importin) alpha 6
chr11_-_119040905	0.470	ENSMUST00000026663.7	Cbx8	chromobox 8
chr10_+_60346851	0.470	ENSMUST00000020301.7 ENSMUST00000105460.1 ENSMUST00000170507.1	4632428N05Rik	RIKEN cDNA 4632428N05 gene
chr13_+_96542602	0.466	ENSMUST00000179226.1	Col4a3bp	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr5_-_90223923	0.452	ENSMUST00000118816.1 ENSMUST00000048363.7	Cox18	cytochrome c oxidase assembly protein 18
chr9_-_9239019	0.443	ENSMUST00000183182.1	Arhgap42	Rho GTPase activating protein 42
chr2_+_119547697	0.437	ENSMUST00000014221.6 ENSMUST00000119172.1	Chp1	calcineurin-like EF hand protein 1
chr5_+_146948640	0.425	ENSMUST00000146511.1 ENSMUST00000132102.1	Gtf3a	general transcription factor III A
chr7_+_24507057	0.402	ENSMUST00000071361.6	Zfp428	zinc finger protein 428
chr11_-_120731944	0.402	ENSMUST00000154565.1 ENSMUST00000026148.2	Cbr2	carbonyl reductase 2
chr11_+_58978093	0.394	ENSMUST00000108809.1 ENSMUST00000108810.3 ENSMUST00000093061.6	Trim11	tripartite motif-containing 11
chr15_+_102144362	0.383	ENSMUST00000023807.6	Igfbp6	insulin-like growth factor binding protein 6
chr18_-_52529692	0.378	ENSMUST00000025409.7	Lox	lysyl oxidase
chr9_-_9239052	0.377	ENSMUST00000093893.5	Arhgap42	Rho GTPase activating protein 42
chr3_-_85722474	0.364	ENSMUST00000119077.1	Fam160a1	family with sequence similarity 160, member A1
chr6_+_149408973	0.353	ENSMUST00000086829.4 ENSMUST00000111513.2	Bicd1	bicaudal D homolog 1 (Drosophila)
chr3_+_116007457	0.352	ENSMUST00000029575.5 ENSMUST00000106501.1	Extl2	exostoses (multiple)-like 2
chr11_+_98809787	0.337	ENSMUST00000169695.1	Casc3	cancer susceptibility candidate 3
chr12_+_81859964	0.327	ENSMUST00000021567.5	Pcnx	pecanex homolog (Drosophila)
chr7_-_44849075	0.318	ENSMUST00000047085.8	Tbc1d17	TBC1 domain family, member 17
chr5_-_137531952	0.306	ENSMUST00000140139.1	Gnb2	guanine nucleotide binding protein (G protein), beta 2
chr15_-_76723814	0.304	ENSMUST00000036247.8	C030006K11Rik	RIKEN cDNA C030006K11 gene
chr1_-_121327734	0.301	ENSMUST00000160968.1 ENSMUST00000162582.1	Insig2	insulin induced gene 2
chr4_-_132533488	0.297	ENSMUST00000152993.1 ENSMUST00000067496.6	Atpif1	ATPase inhibitory factor 1
chr3_-_116007399	0.292	ENSMUST00000067485.3	Slc30a7	solute carrier family 30 (zinc transporter), member 7
chr15_+_39076885	0.289	ENSMUST00000067072.3	Cthrc1	collagen triple helix repeat containing 1
chr10_-_78412949	0.283	ENSMUST00000062678.9	Rrp1	ribosomal RNA processing 1 homolog (S. cerevisiae)
chr9_+_107581296	0.276	ENSMUST00000040059.2	Hyal3	hyaluronoglucosaminidase 3
chr15_+_76797628	0.270	ENSMUST00000165535.2	Gm17271	predicted gene, 17271
chr1_-_121328024	0.249	ENSMUST00000003818.7	Insig2	insulin induced gene 2
chr19_+_5038826	0.238	ENSMUST00000053705.6	B3gnt1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr7_+_24507122	0.223	ENSMUST00000177205.1	Zfp428	zinc finger protein 428
chr11_-_48902151	0.210	ENSMUST00000109210.1 ENSMUST00000109212.1	Gm5431	predicted gene 5431
chr2_-_119547627	0.209	ENSMUST00000060009.2	Exd1	exonuclease 3'-5' domain containing 1
chr1_-_121327672	0.201	ENSMUST00000159085.1 ENSMUST00000159125.1 ENSMUST00000161818.1	Insig2	insulin induced gene 2
chr7_+_44849216	0.193	ENSMUST00000054343.8	Akt1s1	AKT1 substrate 1 (proline-rich)
chr18_-_80469664	0.191	ENSMUST00000036229.6	Ctdp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chrX_+_36874351	0.190	ENSMUST00000016452.7	Ube2a	ubiquitin-conjugating enzyme E2A
chr11_+_88973928	0.189	ENSMUST00000036649.4 ENSMUST00000107898.3	Coil	coilin
chr1_-_121327776	0.180	ENSMUST00000160688.1	Insig2	insulin induced gene 2
chr3_-_108200415	0.177	ENSMUST00000106654.1	Cyb561d1	cytochrome b-561 domain containing 1
chr9_-_71771535	0.151	ENSMUST00000122065.1 ENSMUST00000121322.1 ENSMUST00000072899.2	Cgnl1	cingulin-like 1
chr19_-_5457397	0.151	ENSMUST00000179549.1	Ccdc85b	coiled-coil domain containing 85B
chr15_-_79774383	0.147	ENSMUST00000069877.5	Dnal4	dynein, axonemal, light chain 4
chr19_-_58455903	0.140	ENSMUST00000131877.1	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1
chr8_-_109693235	0.127	ENSMUST00000034164.4	Ist1	increased sodium tolerance 1 homolog (yeast)
chr15_+_103272893	0.125	ENSMUST00000100162.3	Copz1	coatomer protein complex, subunit zeta 1
chr7_+_19024387	0.125	ENSMUST00000153976.1	Sympk	symplekin
chr7_+_45434876	0.113	ENSMUST00000107766.1	Gys1	glycogen synthase 1, muscle
chr11_+_6561133	0.098	ENSMUST00000160633.1	Ccm2	cerebral cavernous malformation 2
chr11_+_106066055	0.091	ENSMUST00000002048.7	Taco1	translational activator of mitochondrially encoded cytochrome c oxidase I
chr8_-_64693027	0.088	ENSMUST00000048967.7	Cpe	carboxypeptidase E
chr19_+_25236959	0.070	ENSMUST00000049400.8	Kank1	KN motif and ankyrin repeat domains 1
chr3_-_57847478	0.066	ENSMUST00000120289.1 ENSMUST00000066882.8	Pfn2	profilin 2
chr7_+_24176152	0.051	ENSMUST00000086010.5	Zfp114	zinc finger protein 114
chr12_-_72664759	0.040	ENSMUST00000021512.9	Dhrs7	dehydrogenase/reductase (SDR family) member 7
chr8_-_95888510	0.035	ENSMUST00000034097.7	Got2	glutamate oxaloacetate transaminase 2, mitochondrial
chr13_+_96542727	0.032	ENSMUST00000077672.4 ENSMUST00000109444.2	Col4a3bp	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr7_+_101905837	0.024	ENSMUST00000033131.6	Lamtor1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr15_-_79774408	0.017	ENSMUST00000023055.6	Dnal4	dynein, axonemal, light chain 4
chr7_+_44848991	0.006	ENSMUST00000107885.1	Akt1s1	AKT1 substrate 1 (proline-rich)
chr13_+_67863324	0.005	ENSMUST00000078471.5	BC048507	cDNA sequence BC048507
chr3_-_108200807	0.004	ENSMUST00000106655.1 ENSMUST00000065664.6	Cyb561d1	cytochrome b-561 domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.8	GO:0001978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.4	1.8	GO:1904529	regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.4	1.3	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.4	4.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.4	1.2	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.4	0.4	GO:1900275	negative regulation of phospholipase C activity(GO:1900275)
0.3	1.3	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.3	0.9	GO:0060854	patterning of lymph vessels(GO:0060854)
0.2	1.4	GO:0015879	carnitine transport(GO:0015879)
0.2	0.8	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2	0.6	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2	2.0	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
0.2	0.5	GO:0035621	ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1	0.7	GO:0015671	oxygen transport(GO:0015671)
0.1	0.4	GO:0006116	NADH oxidation(GO:0006116)
0.1	0.9	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	1.3	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	1.8	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.1	0.4	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1	1.1	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.1	0.6	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.1	0.4	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	1.1	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.1	0.6	GO:0042359	vitamin D metabolic process(GO:0042359)
0.1	0.6	GO:0033184	positive regulation of histone ubiquitination(GO:0033184)
0.1	0.4	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.1	0.5	GO:0051204	protein insertion into mitochondrial membrane(GO:0051204)
0.1	0.7	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	1.7	GO:0048148	behavioral response to cocaine(GO:0048148)
0.1	0.3	GO:1901526	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1	2.3	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.3	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	2.4	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	1.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0009838	abscission(GO:0009838)
0.0	0.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.7	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.0	4.9	GO:0014065	phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0	0.5	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.3	GO:0061088	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0	0.5	GO:0006098	pentose-phosphate shunt(GO:0006098)
0.0	0.3	GO:0033690	positive regulation of osteoblast proliferation(GO:0033690)
0.0	1.4	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.1	GO:0030070	insulin processing(GO:0030070)
0.0	0.3	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.5	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.0	0.4	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.1	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0	0.5	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.0	0.5	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.2	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.2	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.2	GO:2000580	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	1.2	GO:1901607	alpha-amino acid biosynthetic process(GO:1901607)
0.0	0.7	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0	0.6	GO:0007566	embryo implantation(GO:0007566)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.2	1.8	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	1.3	GO:0070852	cell body fiber(GO:0070852)
0.1	1.2	GO:0098845	postsynaptic endosome(GO:0098845)
0.1	1.3	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	0.7	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.6	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	5.0	GO:0016459	myosin complex(GO:0016459)
0.1	0.4	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	2.0	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	2.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	2.0	GO:0097440	apical dendrite(GO:0097440)
0.0	1.8	GO:0031941	filamentous actin(GO:0031941)
0.0	0.4	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.2	GO:0001674	female germ cell nucleus(GO:0001674)
0.0	0.3	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.2	GO:0033503	HULC complex(GO:0033503)
0.0	0.6	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	2.4	GO:0036126	sperm flagellum(GO:0036126)
0.0	1.5	GO:0005581	collagen trimer(GO:0005581)
0.0	3.4	GO:0001650	fibrillar center(GO:0001650)
0.0	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.0	1.0	GO:0005902	microvillus(GO:0005902)
0.0	1.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.9	GO:0031514	motile cilium(GO:0031514)
0.0	3.2	GO:0008021	synaptic vesicle(GO:0008021)
0.0	0.1	GO:0090543	Flemming body(GO:0090543)
0.0	0.3	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.7	GO:0005844	polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4	4.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.4	1.4	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.3	2.8	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.2	1.4	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.2	0.5	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2	0.7	GO:0031721	hemoglobin alpha binding(GO:0031721)
0.2	0.5	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.2	0.5	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
0.1	1.2	GO:0032051	clathrin light chain binding(GO:0032051)
0.1	1.8	GO:0031005	filamin binding(GO:0031005)
0.1	0.4	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.1	0.4	GO:0001888	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1	1.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.4	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	0.4	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.6	GO:0045322	unmethylated CpG binding(GO:0045322)
0.1	0.5	GO:0097001	ceramide binding(GO:0097001)
0.1	0.6	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.1	1.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	1.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	1.1	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	0.3	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.1	0.7	GO:1990715	mRNA CDS binding(GO:1990715)
0.1	0.3	GO:0043532	angiostatin binding(GO:0043532)
0.1	1.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.6	GO:0035005	lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	2.0	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.4	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	1.2	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.5	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.8	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	2.0	GO:0015485	cholesterol binding(GO:0015485)
0.0	5.2	GO:0003774	motor activity(GO:0003774)
0.0	0.4	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.7	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	1.7	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.5	GO:0070628	proteasome binding(GO:0070628)
0.0	2.1	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.5	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.0	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0	2.7	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.9	GO:0005262	calcium channel activity(GO:0005262)
0.0	2.9	GO:0061630	ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.4	PID_THROMBIN_PAR4_PATHWAY	PAR4-mediated thrombin signaling events
0.1	1.4	PID_S1P_S1P4_PATHWAY	S1P4 pathway
0.1	0.6	ST_INTERFERON_GAMMA_PATHWAY	Interferon gamma pathway.
0.0	1.3	PID_BETA_CATENIN_DEG_PATHWAY	Degradation of beta catenin
0.0	4.7	NABA_ECM_GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	2.0	PID_MYC_REPRESS_PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.3	PID_AP1_PATHWAY	AP-1 transcription factor network
0.0	1.2	PID_CERAMIDE_PATHWAY	Ceramide signaling pathway
0.0	0.6	PID_KIT_PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.0	PID_TRKR_PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.5	PID_LIS1_PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.7	PID_HDAC_CLASSII_PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.4	PID_IL4_2PATHWAY	IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	4.2	REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS	Genes involved in Tandem pore domain potassium channels
0.3	2.8	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.2	1.4	REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.2	2.3	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	1.6	REACTOME_ZINC_TRANSPORTERS	Genes involved in Zinc transporters
0.1	3.7	REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	1.8	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.3	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	1.3	REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	1.1	REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.6	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	1.4	REACTOME_PLC_BETA_MEDIATED_EVENTS	Genes involved in PLC beta mediated events
0.0	0.4	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.6	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	1.4	REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.5	REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME_COPI_MEDIATED_TRANSPORT	Genes involved in COPI Mediated Transport