Motif ID: Zbtb49

Z-value: 0.292


Transcription factors associated with Zbtb49:

Gene SymbolEntrez IDGene Name
Zbtb49 ENSMUSG00000029127.9 Zbtb49

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb49mm10_v2_chr5_-_38220400_382204590.358.8e-03Click!


Activity profile for motif Zbtb49.

activity profile for motif Zbtb49


Sorted Z-values histogram for motif Zbtb49

Sorted Z-values for motif Zbtb49



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb49

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_140154712 2.959 ENSMUST00000059241.7
 Sprn
shadow of prion protein
chr18_-_61911783 1.907 ENSMUST00000049378.8
ENSMUST00000166783.1
 Ablim3

actin binding LIM protein family, member 3

chr9_+_40269430 1.771 ENSMUST00000171835.2
 Scn3b
sodium channel, voltage-gated, type III, beta
chr9_+_40269273 1.594 ENSMUST00000176185.1
 Scn3b
sodium channel, voltage-gated, type III, beta
chr9_+_40269202 1.529 ENSMUST00000114956.3
ENSMUST00000049941.5
 Scn3b

sodium channel, voltage-gated, type III, beta

chr1_+_32172711 1.319 ENSMUST00000027226.5
 Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr9_+_50856924 0.961 ENSMUST00000174628.1
ENSMUST00000034560.7
ENSMUST00000114437.2
ENSMUST00000175645.1
ENSMUST00000176349.1
ENSMUST00000176798.1
ENSMUST00000175640.1
 Ppp2r1b






protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform






chr18_+_23753708 0.881 ENSMUST00000115830.1
 Mapre2
microtubule-associated protein, RP/EB family, member 2
chr15_-_102257449 0.870 ENSMUST00000043172.8
 Rarg
retinoic acid receptor, gamma
chr7_+_4460687 0.818 ENSMUST00000167298.1
ENSMUST00000171445.1
 Eps8l1

EPS8-like 1

chr9_+_45430293 0.806 ENSMUST00000034592.8
 Dscaml1
Down syndrome cell adhesion molecule like 1
chr15_-_102257306 0.799 ENSMUST00000135466.1
 Rarg
retinoic acid receptor, gamma
chr5_-_108629712 0.614 ENSMUST00000046603.8
 Gak
cyclin G associated kinase
chr15_-_100422991 0.514 ENSMUST00000138843.1
ENSMUST00000023774.5
 Slc11a2

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

chr5_+_108629990 0.505 ENSMUST00000078323.6
ENSMUST00000120327.1
 Tmem175

transmembrane protein 175

chr5_+_108629791 0.359 ENSMUST00000063272.6
 Tmem175
transmembrane protein 175
chr8_+_4493443 0.322 ENSMUST00000175781.2
 Cers4
ceramide synthase 4
chr17_+_32993123 0.308 ENSMUST00000087666.4
ENSMUST00000157017.1
 Zfp952

zinc finger protein 952

chr3_-_53017195 0.278 ENSMUST00000036665.4
 Cog6
component of oligomeric golgi complex 6
chr16_-_70382385 0.219 ENSMUST00000072455.4
 4930423O20Rik
RIKEN cDNA 4930423O20 gene
chr14_-_68655804 0.168 ENSMUST00000111072.1
ENSMUST00000022642.5
 Adam28

a disintegrin and metallopeptidase domain 28

chr1_-_183369529 0.111 ENSMUST00000069922.5
 Mia3
melanoma inhibitory activity 3
chr6_+_59208870 0.089 ENSMUST00000062626.3
 Tigd2
tigger transposable element derived 2
chr3_-_154597045 0.008 ENSMUST00000052774.1
ENSMUST00000170461.1
ENSMUST00000122976.1
 Tyw3


tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.9 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.4 1.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 0.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.5 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.9 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 1.0 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 1.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.3 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 3.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.8 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 4.9 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.8 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 1.0 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.9 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway