Motif ID: Zfp105

Z-value: 0.508


Transcription factors associated with Zfp105:

Gene SymbolEntrez IDGene Name
Zfp105 ENSMUSG00000057895.5 Zfp105

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp105mm10_v2_chr9_+_122923050_1229230990.574.7e-06Click!


Activity profile for motif Zfp105.

activity profile for motif Zfp105


Sorted Z-values histogram for motif Zfp105

Sorted Z-values for motif Zfp105



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp105

PNG image of the network

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Top targets:


Showing 1 to 20 of 43 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_144892813 4.321 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr5_+_17574268 3.065 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_-_190170671 2.971 ENSMUST00000175916.1
 Prox1
prospero-related homeobox 1
chr2_-_91931774 2.161 ENSMUST00000069423.6
 Mdk
midkine
chr4_+_11704439 1.962 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr5_-_111761697 1.917 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr6_-_127151044 1.867 ENSMUST00000000188.8
 Ccnd2
cyclin D2
chr5_+_13399309 1.822 ENSMUST00000030714.7
ENSMUST00000141968.1
 Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr8_+_128359065 1.768 ENSMUST00000026917.8
 Nrp1
neuropilin 1
chr18_+_69344503 1.281 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr18_+_35829798 1.049 ENSMUST00000060722.6
 Cxxc5
CXXC finger 5
chr9_-_78378725 1.034 ENSMUST00000034900.7
 Ooep
oocyte expressed protein
chr2_-_177267036 0.976 ENSMUST00000108963.1
 Gm14409
predicted gene 14409
chr12_-_90738438 0.974 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr8_-_11008458 0.862 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr8_-_84773381 0.840 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr9_+_58134535 0.780 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
 Stra6



stimulated by retinoic acid gene 6



chr11_-_101466222 0.692 ENSMUST00000040430.7
 Vat1
vesicle amine transport protein 1 homolog (T californica)
chr13_-_67609667 0.601 ENSMUST00000012873.8
 AA987161
expressed sequence AA987161
chr11_-_100411874 0.595 ENSMUST00000141840.1
 Leprel4
leprecan-like 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 6.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4 4.3 GO:0042572 retinol metabolic process(GO:0042572)
1.0 3.0 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.7 2.2 GO:0030421 defecation(GO:0030421)
0.2 2.0 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 1.9 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 1.3 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.0 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.0 1.0 GO:0007566 embryo implantation(GO:0007566)
0.1 0.9 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 0.8 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.1 0.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.2 0.5 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:2000054 regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0051233 spindle midzone(GO:0051233)
0.5 1.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.8 GO:0097443 sorting endosome(GO:0097443)
0.0 0.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.9 GO:0038191 neuropilin binding(GO:0038191)
0.6 4.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 3.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 2.2 GO:0008083 growth factor activity(GO:0008083)
0.0 2.0 GO:0019003 GDP binding(GO:0019003)
0.4 1.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.2 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.9 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 1.8 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID_EPO_PATHWAY EPO signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.6 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.0 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis