Motif ID: Zfp148
Z-value: 1.022
Transcription factors associated with Zfp148:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zfp148 | ENSMUSG00000022811.10 | Zfp148 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zfp148 | mm10_v2_chr16_+_33380765_33380787 | 0.72 | 6.8e-10 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 162 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 28.9 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 3.6 | 21.6 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 2.0 | 13.8 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
| 2.3 | 13.7 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.1 | 7.8 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.6 | 7.0 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.0 | 6.5 | GO:0007411 | axon guidance(GO:0007411) |
| 0.0 | 6.1 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
| 1.2 | 5.8 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
| 0.9 | 5.7 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.2 | 5.6 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 1.0 | 5.2 | GO:0046113 | nucleobase catabolic process(GO:0046113) |
| 1.7 | 5.0 | GO:1904978 | regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980) |
| 1.2 | 4.7 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 1.5 | 4.6 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
| 0.8 | 4.6 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.1 | 4.6 | GO:0021696 | cerebellar cortex morphogenesis(GO:0021696) |
| 0.2 | 4.2 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.8 | 4.1 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
| 0.6 | 4.1 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 75 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 22.2 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 21.5 | GO:0030425 | dendrite(GO:0030425) |
| 0.1 | 16.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 14.2 | GO:0005615 | extracellular space(GO:0005615) |
| 3.5 | 13.8 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 4.6 | 13.7 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.4 | 8.3 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.1 | 6.4 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.2 | 5.0 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 0.1 | 4.8 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.8 | 4.6 | GO:0008091 | spectrin(GO:0008091) |
| 0.3 | 4.6 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 4.6 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 4.6 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.2 | 3.9 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 3.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 3.2 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 3.1 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 3.1 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.2 | 2.8 | GO:0000124 | SAGA complex(GO:0000124) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 115 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 23.3 | GO:0038191 | neuropilin binding(GO:0038191) |
| 2.0 | 13.7 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.1 | 13.7 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
| 0.1 | 12.4 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 11.8 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.2 | 11.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.2 | 8.8 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 6.8 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.1 | 6.7 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.7 | 6.1 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.6 | 5.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.0 | 5.5 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.3 | 5.3 | GO:0030955 | potassium ion binding(GO:0030955) |
| 1.0 | 5.0 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.1 | 4.3 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 1.4 | 4.1 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.3 | 4.1 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
| 0.2 | 3.8 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 3.8 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.1 | 3.7 | GO:0005080 | protein kinase C binding(GO:0005080) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 30 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 23.3 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 14.8 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 5.3 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.1 | 3.0 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.1 | 2.9 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.0 | 2.9 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 2.6 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 2.6 | PID_INSULIN_PATHWAY | Insulin Pathway |
| 0.0 | 2.5 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 2.1 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 1.9 | PID_P73PATHWAY | p73 transcription factor network |
| 0.1 | 1.7 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 1.6 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 1.5 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
| 0.1 | 1.4 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 1.4 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 1.3 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 1.3 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.3 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.1 | 1.2 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 46 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 14.4 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.2 | 8.5 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.4 | 7.1 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.3 | 6.3 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.2 | 5.6 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.3 | 5.3 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 5.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.2 | 4.3 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.4 | 3.1 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.2 | 3.0 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.1 | 3.0 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.3 | 2.6 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 1.9 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 1.7 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.7 | 1.5 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
| 0.1 | 1.4 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 1.4 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 1.3 | REACTOME_IL_RECEPTOR_SHC_SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 1.3 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.2 | 1.2 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
