Motif ID: Zfp148

Z-value: 1.022


Transcription factors associated with Zfp148:

Gene SymbolEntrez IDGene Name
Zfp148 ENSMUSG00000022811.10 Zfp148

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp148mm10_v2_chr16_+_33380765_333807870.726.8e-10Click!


Activity profile for motif Zfp148.

activity profile for motif Zfp148


Sorted Z-values histogram for motif Zfp148

Sorted Z-values for motif Zfp148



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp148

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_98032983 16.635 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr8_+_70493156 13.657 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr6_+_103510874 11.686 ENSMUST00000066905.6
Chl1
cell adhesion molecule with homology to L1CAM
chr9_-_40455670 11.124 ENSMUST00000165104.1
ENSMUST00000045682.5
Gramd1b

GRAM domain containing 1B

chr5_+_17574726 10.970 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_17574268 10.612 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr11_-_102897123 8.500 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr10_+_13966268 7.526 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr10_+_106470281 5.807 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr4_-_138396438 5.726 ENSMUST00000105032.2
Fam43b
family with sequence similarity 43, member B
chr2_+_107290590 5.319 ENSMUST00000037012.2
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr11_-_102897146 5.310 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr9_-_29411736 5.290 ENSMUST00000115236.1
Ntm
neurotrimin
chr2_-_104409992 5.159 ENSMUST00000149466.1
ENSMUST00000139015.1
D430041D05Rik

RIKEN cDNA D430041D05 gene

chr2_-_104410334 4.761 ENSMUST00000089726.3
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr9_-_29412204 4.741 ENSMUST00000115237.1
Ntm
neurotrimin
chr17_-_68004075 4.699 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr7_-_27396542 4.609 ENSMUST00000108363.1
Sptbn4
spectrin beta, non-erythrocytic 4
chr4_-_133498538 4.550 ENSMUST00000125541.1
Trnp1
TMF1-regulated nuclear protein 1
chr10_+_127078886 4.080 ENSMUST00000039259.6
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr11_+_3332426 4.052 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr2_+_32741452 3.953 ENSMUST00000131101.1
Sh2d3c
SH2 domain containing 3C
chr4_-_149774238 3.611 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr10_+_3366125 3.587 ENSMUST00000043374.5
Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr5_+_30711564 3.551 ENSMUST00000114729.1
Dpysl5
dihydropyrimidinase-like 5
chr5_+_30711849 3.541 ENSMUST00000088081.4
ENSMUST00000101442.3
Dpysl5

dihydropyrimidinase-like 5

chr11_+_105589970 3.309 ENSMUST00000168598.1
ENSMUST00000100330.3
Tanc2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr4_-_41774097 3.298 ENSMUST00000108036.1
ENSMUST00000173865.1
ENSMUST00000108037.2
ENSMUST00000108032.2
Ccl27a



chemokine (C-C motif) ligand 27A



chr3_-_127499095 3.242 ENSMUST00000182594.1
Ank2
ankyrin 2, brain
chr7_-_126949499 3.207 ENSMUST00000106339.1
ENSMUST00000052937.5
Asphd1

aspartate beta-hydroxylase domain containing 1

chr15_-_75566811 3.184 ENSMUST00000065417.8
Ly6h
lymphocyte antigen 6 complex, locus H
chr1_-_21961942 3.144 ENSMUST00000115300.1
Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
chr5_+_30588078 3.079 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr2_-_146511992 3.078 ENSMUST00000109986.2
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr8_+_84723003 3.052 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr6_+_124997062 3.016 ENSMUST00000159391.1
Pianp
PILR alpha associated neural protein
chr1_-_134235420 2.964 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr18_+_67933257 2.950 ENSMUST00000063775.3
Ldlrad4
low density lipoprotein receptor class A domain containing 4
chr15_-_75566608 2.941 ENSMUST00000163116.1
ENSMUST00000023241.5
Ly6h

lymphocyte antigen 6 complex, locus H

chr6_-_53068562 2.910 ENSMUST00000074541.5
Jazf1
JAZF zinc finger 1
chr19_+_37550397 2.871 ENSMUST00000066439.6
Exoc6
exocyst complex component 6
chr3_+_36863102 2.844 ENSMUST00000057272.8
4932438A13Rik
RIKEN cDNA 4932438A13 gene
chr19_-_21472552 2.782 ENSMUST00000087600.3
Gda
guanine deaminase
chr11_-_102296618 2.770 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr12_+_55836365 2.770 ENSMUST00000059250.6
Brms1l
breast cancer metastasis-suppressor 1-like
chr11_-_54068932 2.764 ENSMUST00000093109.4
ENSMUST00000018755.3
Pdlim4

PDZ and LIM domain 4

chr2_-_146511899 2.757 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chrX_-_8206475 2.733 ENSMUST00000089403.3
ENSMUST00000077595.5
ENSMUST00000089402.3
ENSMUST00000082320.5
Porcn



porcupine homolog (Drosophila)



chr11_-_101226414 2.717 ENSMUST00000100417.2
ENSMUST00000107285.1
ENSMUST00000107284.1
Ezh1


enhancer of zeste homolog 1 (Drosophila)


chr5_+_8660059 2.673 ENSMUST00000047753.4
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr7_+_16310412 2.656 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr9_+_54699548 2.568 ENSMUST00000070070.7
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr9_+_54698859 2.551 ENSMUST00000120452.1
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr14_+_123659971 2.522 ENSMUST00000049681.7
Itgbl1
integrin, beta-like 1
chr15_+_79108911 2.480 ENSMUST00000040320.8
Micall1
microtubule associated monooxygenase, calponin and LIM domain containing -like 1
chr2_+_136713444 2.410 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr10_+_98915117 2.299 ENSMUST00000020107.7
Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr17_-_24689901 2.277 ENSMUST00000007236.4
Syngr3
synaptogyrin 3
chr9_+_109931863 2.257 ENSMUST00000165876.1
Map4
microtubule-associated protein 4
chr18_-_37969742 2.252 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chrX_-_103821940 2.218 ENSMUST00000042664.5
Slc16a2
solute carrier family 16 (monocarboxylic acid transporters), member 2
chr7_+_49974864 2.215 ENSMUST00000081872.5
ENSMUST00000151721.1
Nell1

NEL-like 1

chr6_-_85502980 2.208 ENSMUST00000159062.1
Fbxo41
F-box protein 41
chr7_+_28766747 2.170 ENSMUST00000170068.1
ENSMUST00000072965.4
Sirt2

sirtuin 2

chr4_+_108879130 2.170 ENSMUST00000106651.2
Rab3b
RAB3B, member RAS oncogene family
chr7_+_44384803 2.155 ENSMUST00000120262.1
Syt3
synaptotagmin III
chr2_-_73386396 2.145 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr17_+_79051906 2.134 ENSMUST00000040789.4
Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chrX_-_7375830 2.102 ENSMUST00000115744.1
Usp27x
ubiquitin specific peptidase 27, X chromosome
chr11_+_97450136 2.082 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr12_+_69197200 2.066 ENSMUST00000181850.1
9330151L19Rik
RIKEN cDNA 9330151L19 gene
chr4_+_136310991 2.036 ENSMUST00000084219.5
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr4_+_62286441 2.030 ENSMUST00000084530.2
Slc31a2
solute carrier family 31, member 2
chr7_+_44384604 2.028 ENSMUST00000130707.1
ENSMUST00000130844.1
Syt3

synaptotagmin III

chr16_-_91011308 2.024 ENSMUST00000121759.1
Synj1
synaptojanin 1
chr9_-_107710475 1.995 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_+_46490968 1.988 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1

acyl-CoA synthetase long-chain family member 1

chr4_+_85205417 1.987 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
Sh3gl2


SH3-domain GRB2-like 2


chr11_-_72266596 1.985 ENSMUST00000021161.6
ENSMUST00000140167.1
Slc13a5

solute carrier family 13 (sodium-dependent citrate transporter), member 5

chr7_+_49975228 1.956 ENSMUST00000107603.1
Nell1
NEL-like 1
chr7_-_142659482 1.947 ENSMUST00000121128.1
Igf2
insulin-like growth factor 2
chr2_-_25461021 1.929 ENSMUST00000151239.1
BC029214
cDNA sequence BC029214
chr9_+_54699514 1.905 ENSMUST00000154690.1
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr10_+_70440844 1.889 ENSMUST00000173042.1
ENSMUST00000062883.6
Fam13c

family with sequence similarity 13, member C

chr2_-_25461094 1.855 ENSMUST00000114261.2
BC029214
cDNA sequence BC029214
chr12_-_109068173 1.854 ENSMUST00000073156.7
Begain
brain-enriched guanylate kinase-associated
chr4_+_136310936 1.850 ENSMUST00000131671.1
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chrX_+_99975570 1.826 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr11_+_83302641 1.806 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chrX_+_94234594 1.785 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr7_+_45627482 1.750 ENSMUST00000057927.7
Rasip1
Ras interacting protein 1
chr2_+_118663235 1.743 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr4_+_41942037 1.721 ENSMUST00000181518.1
Gm20878
predicted gene, 20878
chr4_+_136310952 1.720 ENSMUST00000105850.1
ENSMUST00000148843.3
Hnrnpr

heterogeneous nuclear ribonucleoprotein R

chr4_-_108780503 1.715 ENSMUST00000106658.1
Zfyve9
zinc finger, FYVE domain containing 9
chr10_+_128499364 1.701 ENSMUST00000180477.1
A430046D13Rik
Riken cDNA A430046D13 gene
chr10_+_70440643 1.685 ENSMUST00000105436.2
Fam13c
family with sequence similarity 13, member C
chr3_-_94658800 1.681 ENSMUST00000107277.1
ENSMUST00000006123.4
ENSMUST00000107279.2
Tuft1


tuftelin 1


chr3_-_90389884 1.660 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr4_+_108879063 1.652 ENSMUST00000106650.2
Rab3b
RAB3B, member RAS oncogene family
chr16_-_91011093 1.634 ENSMUST00000170853.1
ENSMUST00000118390.2
Synj1

synaptojanin 1

chr3_+_90266507 1.633 ENSMUST00000098914.3
Dennd4b
DENN/MADD domain containing 4B
chr15_+_89499598 1.623 ENSMUST00000109309.1
Shank3
SH3/ankyrin domain gene 3
chr15_+_99295087 1.607 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr19_-_29805989 1.604 ENSMUST00000177155.1
ENSMUST00000059484.7
9930021J03Rik

RIKEN cDNA 9930021J03 gene

chr2_-_120850389 1.590 ENSMUST00000143051.1
ENSMUST00000057135.7
ENSMUST00000085840.4
Ttbk2


tau tubulin kinase 2


chr9_+_59589288 1.571 ENSMUST00000121266.1
ENSMUST00000118164.1
Celf6

CUGBP, Elav-like family member 6

chr11_+_103649498 1.534 ENSMUST00000057870.2
Rprml
reprimo-like
chr2_-_161109017 1.525 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr8_+_93810832 1.495 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr11_+_83302817 1.484 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr11_-_87359011 1.479 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr2_-_120850364 1.476 ENSMUST00000131389.1
Ttbk2
tau tubulin kinase 2
chr7_+_29134854 1.466 ENSMUST00000161522.1
ENSMUST00000159975.1
ENSMUST00000032811.5
ENSMUST00000094617.4
Rasgrp4



RAS guanyl releasing protein 4



chr14_-_118925314 1.461 ENSMUST00000004055.8
Dzip1
DAZ interacting protein 1
chr11_+_49203285 1.446 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chrX_+_73716712 1.441 ENSMUST00000114461.2
Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr12_-_84450944 1.437 ENSMUST00000085192.5
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr19_+_46356880 1.432 ENSMUST00000086969.6
ENSMUST00000128455.1
Tmem180

transmembrane protein 180

chr3_-_89093358 1.415 ENSMUST00000090929.5
ENSMUST00000052539.6
Rusc1

RUN and SH3 domain containing 1

chr7_-_47132698 1.405 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr2_-_60963192 1.394 ENSMUST00000028347.6
Rbms1
RNA binding motif, single stranded interacting protein 1
chr4_+_43669266 1.390 ENSMUST00000107864.1
Tmem8b
transmembrane protein 8B
chr16_-_91011029 1.387 ENSMUST00000130813.1
Synj1
synaptojanin 1
chr16_+_18127607 1.384 ENSMUST00000059589.5
Rtn4r
reticulon 4 receptor
chr6_-_39118211 1.365 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr17_+_35823509 1.364 ENSMUST00000173493.1
ENSMUST00000173147.1
ENSMUST00000172846.1
Flot1


flotillin 1


chr11_+_50225315 1.363 ENSMUST00000041725.7
Mgat4b
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chr3_+_68572245 1.325 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr18_+_64340225 1.319 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr16_+_17797282 1.309 ENSMUST00000012161.3
Scarf2
scavenger receptor class F, member 2
chr10_-_128498676 1.305 ENSMUST00000026428.3
Myl6b
myosin, light polypeptide 6B
chr17_+_35823230 1.303 ENSMUST00000001569.8
ENSMUST00000174080.1
Flot1

flotillin 1

chr2_+_121866918 1.300 ENSMUST00000078752.3
ENSMUST00000110586.3
Casc4

cancer susceptibility candidate 4

chr8_-_70234097 1.298 ENSMUST00000130319.1
Armc6
armadillo repeat containing 6
chr7_+_25686994 1.297 ENSMUST00000002678.9
Tgfb1
transforming growth factor, beta 1
chr16_-_94997653 1.284 ENSMUST00000095873.4
ENSMUST00000099508.2
Kcnj6

potassium inwardly-rectifying channel, subfamily J, member 6

chr6_-_122340200 1.282 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr7_+_97081711 1.281 ENSMUST00000004622.5
Gab2
growth factor receptor bound protein 2-associated protein 2
chr2_-_130642770 1.264 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr7_-_25005895 1.257 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr10_-_81545175 1.243 ENSMUST00000043604.5
Gna11
guanine nucleotide binding protein, alpha 11
chr2_+_163602331 1.243 ENSMUST00000152135.1
Ttpal
tocopherol (alpha) transfer protein-like
chr7_+_66689889 1.237 ENSMUST00000153007.1
ENSMUST00000177726.1
ENSMUST00000121777.2
ENSMUST00000150071.1
ENSMUST00000077967.6
Lins




lines homolog (Drosophila)




chr15_-_83510793 1.229 ENSMUST00000154401.1
Ttll1
tubulin tyrosine ligase-like 1
chrX_+_153237748 1.192 ENSMUST00000112574.2
Klf8
Kruppel-like factor 8
chr17_+_47688992 1.190 ENSMUST00000156118.1
Frs3
fibroblast growth factor receptor substrate 3
chr19_+_8741669 1.189 ENSMUST00000176314.1
ENSMUST00000073430.7
ENSMUST00000175901.1
Stx5a


syntaxin 5A


chr7_-_28766469 1.169 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr8_+_111536492 1.168 ENSMUST00000168428.1
ENSMUST00000171182.1
Znrf1

zinc and ring finger 1

chr12_+_87147703 1.154 ENSMUST00000063117.8
Gstz1
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr19_+_45363734 1.151 ENSMUST00000065601.5
ENSMUST00000111936.2
Btrc

beta-transducin repeat containing protein

chr18_+_36281069 1.132 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr15_-_95528702 1.131 ENSMUST00000166170.1
Nell2
NEL-like 2
chr17_-_45686120 1.131 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr5_-_135078224 1.128 ENSMUST00000067935.4
ENSMUST00000076203.2
Vps37d

vacuolar protein sorting 37D (yeast)

chr4_+_43406435 1.116 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr15_-_83510861 1.115 ENSMUST00000109479.1
ENSMUST00000109480.1
ENSMUST00000016897.4
Ttll1


tubulin tyrosine ligase-like 1


chr2_+_130406478 1.097 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr3_+_95164306 1.075 ENSMUST00000107217.1
ENSMUST00000168321.1
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr4_+_115828061 1.073 ENSMUST00000030477.3
Mob3c
MOB kinase activator 3C
chr2_-_30359278 1.071 ENSMUST00000163668.2
ENSMUST00000028214.8
ENSMUST00000113621.3
Sh3glb2


SH3-domain GRB2-like endophilin B2


chr1_+_57774600 1.058 ENSMUST00000167971.1
ENSMUST00000170139.1
ENSMUST00000171699.1
ENSMUST00000164302.1
Spats2l



spermatogenesis associated, serine-rich 2-like



chr4_-_94979063 1.042 ENSMUST00000075872.3
Mysm1
myb-like, SWIRM and MPN domains 1
chr5_-_107289561 1.027 ENSMUST00000031224.8
Tgfbr3
transforming growth factor, beta receptor III
chr11_+_69846665 1.019 ENSMUST00000019605.2
Plscr3
phospholipid scramblase 3
chr5_+_34525797 1.016 ENSMUST00000125817.1
ENSMUST00000067638.7
Sh3bp2

SH3-domain binding protein 2

chr3_+_89215192 1.015 ENSMUST00000142051.1
ENSMUST00000119084.1
Thbs3

thrombospondin 3

chr14_+_20694956 0.999 ENSMUST00000048016.1
Fut11
fucosyltransferase 11
chr2_+_29965560 0.998 ENSMUST00000113717.1
ENSMUST00000113719.2
ENSMUST00000100225.2
ENSMUST00000113741.1
ENSMUST00000095083.4
ENSMUST00000046257.7
Sptan1





spectrin alpha, non-erythrocytic 1





chr13_-_30974023 0.985 ENSMUST00000021785.6
Exoc2
exocyst complex component 2
chr4_+_126024506 0.985 ENSMUST00000106162.1
Csf3r
colony stimulating factor 3 receptor (granulocyte)
chr18_-_25753852 0.971 ENSMUST00000025117.6
ENSMUST00000115816.2
Celf4

CUGBP, Elav-like family member 4

chr7_-_24587612 0.968 ENSMUST00000094705.2
Zfp575
zinc finger protein 575
chr1_-_180256294 0.965 ENSMUST00000111108.3
Psen2
presenilin 2
chr7_-_43489967 0.964 ENSMUST00000107974.1
Iglon5
IgLON family member 5
chr6_-_119848059 0.948 ENSMUST00000184864.1
Erc1
ELKS/RAB6-interacting/CAST family member 1
chr10_+_127195240 0.947 ENSMUST00000181578.1
F420014N23Rik
RIKEN cDNA F420014N23 gene
chr11_+_106084577 0.942 ENSMUST00000002044.9
Map3k3
mitogen-activated protein kinase kinase kinase 3
chr3_+_118562129 0.938 ENSMUST00000039177.7
Dpyd
dihydropyrimidine dehydrogenase
chr2_-_167062607 0.927 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chr2_-_30359190 0.922 ENSMUST00000100215.4
ENSMUST00000113620.3
Sh3glb2

SH3-domain GRB2-like endophilin B2

chr3_+_106547693 0.914 ENSMUST00000117469.1
ENSMUST00000067630.6
ENSMUST00000134396.1
ENSMUST00000144746.1
ENSMUST00000121034.1
ENSMUST00000029507.6
ENSMUST00000132923.1
ENSMUST00000151465.1
Dram2







DNA-damage regulated autophagy modulator 2







chr4_+_155847393 0.910 ENSMUST00000030948.9
ENSMUST00000168552.1
Dvl1

dishevelled, dsh homolog 1 (Drosophila)

chr12_+_8674391 0.905 ENSMUST00000163569.1
ENSMUST00000169089.1
Pum2

pumilio 2 (Drosophila)

chr11_+_23306884 0.903 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr17_+_7170101 0.897 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr2_+_28513243 0.896 ENSMUST00000028170.8
Ralgds
ral guanine nucleotide dissociation stimulator
chr5_+_26817357 0.885 ENSMUST00000071500.6
Dpp6
dipeptidylpeptidase 6
chr1_-_162859684 0.877 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr15_-_97831460 0.872 ENSMUST00000079838.7
ENSMUST00000118294.1
Hdac7

histone deacetylase 7

chr4_+_43669610 0.870 ENSMUST00000107866.1
Tmem8b
transmembrane protein 8B
chrX_+_73716577 0.866 ENSMUST00000002084.7
Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr6_-_119848120 0.860 ENSMUST00000183703.1
ENSMUST00000183911.1
Erc1

ELKS/RAB6-interacting/CAST family member 1

chr11_+_75651504 0.857 ENSMUST00000069057.6
Myo1c
myosin IC
chr2_-_167062981 0.844 ENSMUST00000048988.7
Znfx1
zinc finger, NFX1-type containing 1
chr5_-_108132541 0.838 ENSMUST00000119437.1
ENSMUST00000118036.1
Tmed5

transmembrane emp24 protein transport domain containing 5

chr11_+_35769462 0.837 ENSMUST00000018990.7
Pank3
pantothenate kinase 3
chr11_+_69846610 0.832 ENSMUST00000152566.1
ENSMUST00000108633.2
Plscr3

phospholipid scramblase 3

chr17_-_24533709 0.815 ENSMUST00000061764.7
Rab26
RAB26, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 21.6 GO:0003350 pulmonary myocardium development(GO:0003350)
2.3 13.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
2.0 13.8 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
1.7 5.0 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
1.5 4.6 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
1.2 4.7 GO:1904425 negative regulation of GTP binding(GO:1904425)
1.2 5.8 GO:0060178 regulation of exocyst localization(GO:0060178)
1.0 5.2 GO:0046113 nucleobase catabolic process(GO:0046113)
1.0 3.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.0 3.8 GO:0097494 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494)
0.9 5.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.9 3.6 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.8 4.1 GO:2001025 positive regulation of response to drug(GO:2001025)
0.8 2.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.8 4.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.7 2.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.7 2.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.7 2.7 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.7 2.6 GO:0015744 succinate transport(GO:0015744)
0.6 7.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.6 1.8 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.6 4.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.5 2.7 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.5 2.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.5 2.3 GO:0051012 microtubule sliding(GO:0051012)
0.4 2.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.4 2.5 GO:0097491 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.4 4.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.4 2.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.4 1.5 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.4 3.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 1.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.3 28.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 1.6 GO:1904717 positive regulation of synapse structural plasticity(GO:0051835) regulation of AMPA glutamate receptor clustering(GO:1904717)
0.3 3.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 1.8 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.3 1.2 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.3 3.2 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.3 2.0 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 1.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.3 2.7 GO:0098532 liver regeneration(GO:0097421) histone H3-K27 trimethylation(GO:0098532)
0.3 1.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.3 1.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.3 2.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.3 1.0 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.3 2.3 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 0.7 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.2 4.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 0.9 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.2 1.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 2.0 GO:0090166 Golgi disassembly(GO:0090166)
0.2 0.6 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.2 2.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 1.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 1.0 GO:0001927 exocyst assembly(GO:0001927)
0.2 3.1 GO:1990403 embryonic brain development(GO:1990403)
0.2 0.9 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 2.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.2 2.0 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 5.6 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 2.5 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.5 GO:0035826 rubidium ion transport(GO:0035826)
0.1 1.3 GO:0030049 muscle filament sliding(GO:0030049)
0.1 1.0 GO:0060346 bone trabecula formation(GO:0060346)
0.1 1.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.3 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
0.1 1.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 3.2 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 1.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.3 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 0.6 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 3.1 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 1.3 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.4 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 3.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.0 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.4 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 1.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 1.0 GO:0043589 skin morphogenesis(GO:0043589)
0.1 4.6 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.1 2.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.3 GO:0001553 luteinization(GO:0001553)
0.1 0.5 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1 0.8 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 1.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.6 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.6 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.6 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.1 GO:1902713 regulation of interferon-gamma secretion(GO:1902713) positive regulation of interferon-gamma secretion(GO:1902715)
0.1 2.4 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 0.9 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 7.8 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 2.8 GO:0019915 lipid storage(GO:0019915)
0.1 0.8 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 1.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 1.0 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 6.5 GO:0007411 axon guidance(GO:0007411)
0.0 0.4 GO:1900194 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.0 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.5 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.3 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 6.1 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 1.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 1.5 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.1 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.0 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.3 GO:0021819 layer formation in cerebral cortex(GO:0021819) radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.0 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) regulation of vascular wound healing(GO:0061043)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.2 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 1.1 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.3 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.4 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.5 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 2.1 GO:0007254 JNK cascade(GO:0007254)
0.0 3.4 GO:0050890 cognition(GO:0050890)
0.0 1.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 2.8 GO:0060070 canonical Wnt signaling pathway(GO:0060070)
0.0 1.0 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 0.1 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0090282 trophectodermal cellular morphogenesis(GO:0001831) trophectodermal cell proliferation(GO:0001834) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
3.5 13.8 GO:0097450 astrocyte end-foot(GO:0097450)
0.8 4.6 GO:0008091 spectrin(GO:0008091)
0.6 2.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.4 8.3 GO:0032279 asymmetric synapse(GO:0032279)
0.4 2.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 1.1 GO:0045160 myosin I complex(GO:0045160)
0.4 2.2 GO:0033010 paranodal junction(GO:0033010)
0.3 1.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.3 1.0 GO:0032437 cuticular plate(GO:0032437)
0.3 2.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 2.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 4.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 2.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 3.9 GO:0000145 exocyst(GO:0000145)
0.2 1.9 GO:0001739 sex chromatin(GO:0001739)
0.2 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 5.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.2 2.8 GO:0000124 SAGA complex(GO:0000124)
0.1 6.4 GO:0030118 clathrin coat(GO:0030118)
0.1 1.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 16.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.8 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 1.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.2 GO:0031430 M band(GO:0031430)
0.1 1.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 3.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 2.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 4.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.9 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.7 GO:0000439 core TFIIH complex(GO:0000439)
0.1 22.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 1.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 3.1 GO:0035869 ciliary transition zone(GO:0035869)
0.1 4.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 1.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.8 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0005940 septin ring(GO:0005940)
0.0 2.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 4.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.9 GO:0070822 Sin3-type complex(GO:0070822)
0.0 21.5 GO:0030425 dendrite(GO:0030425)
0.0 1.9 GO:0031201 SNARE complex(GO:0031201)
0.0 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 14.2 GO:0005615 extracellular space(GO:0005615)
0.0 2.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 3.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 2.7 GO:0005770 late endosome(GO:0005770)
0.0 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.0 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 13.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.8 23.3 GO:0038191 neuropilin binding(GO:0038191)
1.4 4.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.0 5.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.9 2.6 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.7 6.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.7 2.0 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.6 2.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.6 5.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.6 2.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.5 2.7 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.5 2.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.5 2.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.4 3.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 3.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.4 1.7 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.4 1.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.4 1.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.4 2.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4 1.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 4.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.3 1.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 5.3 GO:0030955 potassium ion binding(GO:0030955)
0.3 2.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 1.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 3.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 1.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 0.8 GO:0019002 GMP binding(GO:0019002)
0.3 1.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 1.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 1.2 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 0.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 2.1 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.2 2.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 3.8 GO:0031489 myosin V binding(GO:0031489)
0.2 11.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 2.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 1.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 8.8 GO:0030507 spectrin binding(GO:0030507)
0.1 2.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 2.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.6 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.1 1.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 13.7 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.1 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 4.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.8 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 6.7 GO:0030276 clathrin binding(GO:0030276)
0.1 0.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 2.8 GO:0042805 actinin binding(GO:0042805)
0.1 12.4 GO:0002020 protease binding(GO:0002020)
0.1 2.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.9 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 6.8 GO:0051082 unfolded protein binding(GO:0051082)
0.1 1.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 3.7 GO:0005080 protein kinase C binding(GO:0005080)
0.1 3.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 3.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0071949 FAD binding(GO:0071949)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 2.2 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 1.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 11.8 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 1.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680) DNA binding, bending(GO:0008301)
0.0 1.4 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 1.2 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 1.9 GO:0051117 ATPase binding(GO:0051117)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.4 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 1.1 GO:0051213 dioxygenase activity(GO:0051213)
0.0 5.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 23.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.1 2.6 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 2.1 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 0.5 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 2.9 PID_SHP2_PATHWAY SHP2 signaling
0.1 5.3 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 14.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 1.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.7 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 2.6 PID_INSULIN_PATHWAY Insulin Pathway
0.1 3.0 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.5 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.5 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 1.0 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.3 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.0 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.4 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.9 PID_P73PATHWAY p73 transcription factor network
0.0 2.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 1.2 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 1.3 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.9 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.6 PID_TGFBR_PATHWAY TGF-beta receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 1.5 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.4 3.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.4 14.4 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.4 7.1 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 2.6 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 5.3 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 6.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 3.0 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 4.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 8.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 5.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 1.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 5.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 0.9 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.1 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 3.0 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.3 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.8 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.8 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.9 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 1.2 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 1.3 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 1.2 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.0 0.6 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 0.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)