Motif ID: Zfp263

Z-value: 0.826


Transcription factors associated with Zfp263:

Gene SymbolEntrez IDGene Name
Zfp263 ENSMUSG00000022529.5 Zfp263

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp263mm10_v2_chr16_+_3744089_37441450.009.8e-01Click!


Activity profile for motif Zfp263.

activity profile for motif Zfp263


Sorted Z-values histogram for motif Zfp263

Sorted Z-values for motif Zfp263



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp263

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_12385769 7.949 ENSMUST00000080795.8
 Gm5607
predicted gene 5607
chr11_+_105292637 7.617 ENSMUST00000100335.3
ENSMUST00000021038.4
 Mrc2

mannose receptor, C type 2

chr6_-_6882068 6.408 ENSMUST00000142635.1
ENSMUST00000052609.8
 Dlx5

distal-less homeobox 5

chr18_+_34861200 5.110 ENSMUST00000165033.1
 Egr1
early growth response 1
chr3_+_83766300 4.742 ENSMUST00000029625.7
 Sfrp2
secreted frizzled-related protein 2
chr2_-_71546745 4.609 ENSMUST00000024159.6
 Dlx2
distal-less homeobox 2
chr11_+_112782182 4.130 ENSMUST00000000579.2
 Sox9
SRY-box containing gene 9
chr2_+_31640037 3.793 ENSMUST00000113470.2
 Prdm12
PR domain containing 12
chr1_-_172297989 3.614 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
 Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr1_-_133424377 3.444 ENSMUST00000153799.1
 Sox13
SRY-box containing gene 13
chr2_-_36105271 3.281 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
 Lhx6


LIM homeobox protein 6


chr6_+_6863269 2.901 ENSMUST00000160937.2
ENSMUST00000171311.1
 Dlx6

distal-less homeobox 6

chrX_+_100730178 2.892 ENSMUST00000113744.1
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr14_+_46882854 2.772 ENSMUST00000022386.8
ENSMUST00000100672.3
 Samd4

sterile alpha motif domain containing 4

chr9_+_23223076 2.758 ENSMUST00000071982.5
 Bmper
BMP-binding endothelial regulator
chr9_-_107667375 2.726 ENSMUST00000010208.8
 Slc38a3
solute carrier family 38, member 3
chr13_-_60177357 2.561 ENSMUST00000065086.4
 Gas1
growth arrest specific 1
chr2_+_91256144 2.394 ENSMUST00000154959.1
ENSMUST00000059566.4
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr15_-_103366763 2.296 ENSMUST00000023128.6
 Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr2_+_91257323 2.293 ENSMUST00000111349.2
ENSMUST00000131711.1
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 184 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 8.6 GO:0060166 olfactory pit development(GO:0060166)
0.5 7.9 GO:0030574 collagen catabolic process(GO:0030574)
2.3 7.0 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.3 6.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.5 5.1 GO:0090527 actin filament reorganization(GO:0090527)
0.2 4.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.6 4.7 GO:1904956 dermatome development(GO:0061054) sclerotome development(GO:0061056) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
1.5 4.6 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.3 4.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
2.1 4.1 GO:0072034 renal vesicle induction(GO:0072034)
0.3 3.9 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.8 3.8 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
1.2 3.6 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 3.4 GO:0070206 protein trimerization(GO:0070206)
0.5 3.0 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 2.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 2.8 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.5 2.7 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.1 2.7 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.2 2.6 GO:0042473 outer ear morphogenesis(GO:0042473)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 5.8 GO:0005925 focal adhesion(GO:0005925)
0.0 4.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 4.3 GO:0000139 Golgi membrane(GO:0000139)
0.5 3.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.7 3.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 2.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 2.4 GO:0097422 tubular endosome(GO:0097422)
0.0 2.4 GO:0005884 actin filament(GO:0005884)
0.1 2.3 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.4 2.0 GO:0036449 microtubule minus-end(GO:0036449)
0.2 1.9 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.8 GO:0000785 chromatin(GO:0000785)
0.5 1.4 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.2 1.3 GO:0072687 meiotic spindle(GO:0072687)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.1 GO:0005518 collagen binding(GO:0005518)
0.2 6.3 GO:0071837 HMG box domain binding(GO:0071837)
0.5 5.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.3 5.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.6 5.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.5 4.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 4.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 3.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.5 3.7 GO:1990239 steroid hormone binding(GO:1990239)
0.8 3.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.6 3.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5 3.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 3.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 3.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 3.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.9 2.7 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.0 2.4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.3 2.3 GO:0034452 dynactin binding(GO:0034452)
0.1 2.3 GO:0030371 translation repressor activity(GO:0030371)
0.1 2.1 GO:0043425 bHLH transcription factor binding(GO:0043425)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 5.4 PID_PLK1_PATHWAY PLK1 signaling events
0.2 5.2 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 5.1 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.2 5.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 4.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.2 3.7 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 3.4 NABA_COLLAGENS Genes encoding collagen proteins
0.1 2.7 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.4 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 2.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.9 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.7 PID_FOXO_PATHWAY FoxO family signaling
0.0 1.5 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.4 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 1.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.4 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 6.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 5.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 4.1 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 3.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.7 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.9 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 1.7 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.1 1.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.5 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.5 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.4 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.4 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.3 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.2 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis