Motif ID: Zfp282

Z-value: 0.474


Transcription factors associated with Zfp282:

Gene SymbolEntrez IDGene Name
Zfp282 ENSMUSG00000025821.9 Zfp282

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp282mm10_v2_chr6_+_47877204_478772040.133.5e-01Click!


Activity profile for motif Zfp282.

activity profile for motif Zfp282


Sorted Z-values histogram for motif Zfp282

Sorted Z-values for motif Zfp282



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp282

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_80000292 2.958 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr14_+_75955003 2.789 ENSMUST00000050120.2
Kctd4
potassium channel tetramerisation domain containing 4
chr18_-_35722330 2.603 ENSMUST00000133064.1
Ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr6_-_29507946 2.465 ENSMUST00000101614.3
ENSMUST00000078112.6
Kcp

kielin/chordin-like protein

chr9_+_34904913 2.232 ENSMUST00000045091.6
Kirrel3
kin of IRRE like 3 (Drosophila)
chr11_+_35121126 1.862 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr16_-_85803106 1.767 ENSMUST00000023610.8
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr7_-_28766469 1.611 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr7_+_28766747 1.588 ENSMUST00000170068.1
ENSMUST00000072965.4
Sirt2

sirtuin 2

chr7_-_35556304 1.573 ENSMUST00000040962.5
Nudt19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr17_-_50094277 1.466 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr14_-_70627008 1.464 ENSMUST00000110984.2
Dmtn
dematin actin binding protein
chr9_-_105131775 1.401 ENSMUST00000035179.6
Nudt16
nudix (nucleoside diphosphate linked moiety X)-type motif 16
chr1_+_195017399 1.339 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr9_+_18427543 1.159 ENSMUST00000053326.9
Gm5612
predicted gene 5612
chr4_-_40239779 1.077 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_-_25005895 0.942 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr11_-_109298066 0.926 ENSMUST00000106706.1
Rgs9
regulator of G-protein signaling 9
chr5_+_137569851 0.919 ENSMUST00000031729.8
Tfr2
transferrin receptor 2
chr12_+_9574437 0.891 ENSMUST00000057021.7
Osr1
odd-skipped related 1 (Drosophila)
chr3_-_88950401 0.863 ENSMUST00000090938.4
Dap3
death associated protein 3
chr12_+_111538101 0.780 ENSMUST00000166123.1
Eif5
eukaryotic translation initiation factor 5
chr2_+_3770673 0.727 ENSMUST00000177037.1
Fam107b
family with sequence similarity 107, member B
chr12_+_69241832 0.710 ENSMUST00000063445.6
Klhdc1
kelch domain containing 1
chr8_-_70776650 0.681 ENSMUST00000034296.8
Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr8_-_71395794 0.674 ENSMUST00000049184.7
Ushbp1
Usher syndrome 1C binding protein 1
chr19_-_5085483 0.670 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr5_+_24685815 0.667 ENSMUST00000068825.6
Nub1
negative regulator of ubiquitin-like proteins 1
chr14_+_31336633 0.648 ENSMUST00000022451.7
Capn7
calpain 7
chr7_+_6371364 0.639 ENSMUST00000086323.4
ENSMUST00000108559.2
Zfp78

zinc finger protein 78

chr16_+_11066292 0.614 ENSMUST00000089011.4
Snn
stannin
chr6_+_70844499 0.604 ENSMUST00000034093.8
ENSMUST00000162950.1
Eif2ak3

eukaryotic translation initiation factor 2 alpha kinase 3

chr1_+_134455524 0.581 ENSMUST00000112232.1
ENSMUST00000027725.4
ENSMUST00000116528.1
Klhl12


kelch-like 12


chr7_+_16738410 0.570 ENSMUST00000086112.6
Ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr3_+_90669063 0.543 ENSMUST00000069927.8
S100a8
S100 calcium binding protein A8 (calgranulin A)
chr11_-_109298090 0.513 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chrX_+_166344692 0.510 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr17_-_46680870 0.502 ENSMUST00000165007.1
ENSMUST00000071841.5
Klhdc3

kelch domain containing 3

chr7_-_30072801 0.498 ENSMUST00000183115.1
ENSMUST00000182919.1
ENSMUST00000183190.1
ENSMUST00000080834.8
Zfp82



zinc finger protein 82



chr12_+_70974621 0.490 ENSMUST00000160027.1
ENSMUST00000160864.1
Psma3

proteasome (prosome, macropain) subunit, alpha type 3

chr8_+_25808474 0.459 ENSMUST00000033979.4
Star
steroidogenic acute regulatory protein
chr12_+_72536342 0.438 ENSMUST00000044352.6
Pcnxl4
pecanex-like 4 (Drosophila)
chr8_+_3676299 0.438 ENSMUST00000044857.3
Trappc5
trafficking protein particle complex 5
chrX_+_135993820 0.417 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr3_-_88951146 0.392 ENSMUST00000173135.1
Dap3
death associated protein 3
chr9_+_45430293 0.391 ENSMUST00000034592.8
Dscaml1
Down syndrome cell adhesion molecule like 1
chr10_-_42018363 0.377 ENSMUST00000162405.1
ENSMUST00000095729.4
ENSMUST00000161081.1
ENSMUST00000160262.2
Armc2



armadillo repeat containing 2



chr13_+_96542602 0.336 ENSMUST00000179226.1
Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr13_-_108158584 0.330 ENSMUST00000163558.1
Ndufaf2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2
chr13_+_96542727 0.318 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr2_-_91444622 0.287 ENSMUST00000064652.7
ENSMUST00000102594.4
ENSMUST00000094835.2
1110051M20Rik


RIKEN cDNA 1110051M20 gene


chr1_+_151344472 0.271 ENSMUST00000023918.6
ENSMUST00000097543.1
ENSMUST00000111887.3
Ivns1abp


influenza virus NS1A binding protein


chr12_+_87443896 0.253 ENSMUST00000161023.1
ENSMUST00000160488.1
ENSMUST00000077462.7
ENSMUST00000160880.1
Slirp



SRA stem-loop interacting RNA binding protein



chr19_-_5488271 0.248 ENSMUST00000124334.1
Mus81
MUS81 endonuclease homolog (yeast)
chr3_-_88951090 0.247 ENSMUST00000173021.1
Dap3
death associated protein 3
chr13_-_53377355 0.243 ENSMUST00000021920.6
Sptlc1
serine palmitoyltransferase, long chain base subunit 1
chr7_-_90457167 0.233 ENSMUST00000032844.5
Tmem126a
transmembrane protein 126A
chr7_-_105640308 0.231 ENSMUST00000133519.1
ENSMUST00000084782.2
ENSMUST00000131446.1
Arfip2


ADP-ribosylation factor interacting protein 2


chr17_+_26941420 0.230 ENSMUST00000081285.3
ENSMUST00000177932.1
Syngap1

synaptic Ras GTPase activating protein 1 homolog (rat)

chr7_-_46919915 0.227 ENSMUST00000143413.1
ENSMUST00000014546.8
Tsg101

tumor susceptibility gene 101

chr19_+_18631927 0.210 ENSMUST00000159572.1
ENSMUST00000042392.7
Nmrk1

nicotinamide riboside kinase 1

chr4_-_53262547 0.207 ENSMUST00000098075.2
AI427809
expressed sequence AI427809
chr15_+_103272893 0.187 ENSMUST00000100162.3
Copz1
coatomer protein complex, subunit zeta 1
chr9_+_120571498 0.181 ENSMUST00000165532.1
Rpl14
ribosomal protein L14
chr2_+_35622160 0.176 ENSMUST00000112992.2
Dab2ip
disabled 2 interacting protein
chr3_-_88950271 0.172 ENSMUST00000174402.1
ENSMUST00000174077.1
Dap3

death associated protein 3

chr13_+_67779754 0.160 ENSMUST00000164936.2
ENSMUST00000181319.1
Zfp493

zinc finger protein 493

chr3_-_121283096 0.138 ENSMUST00000135818.1
ENSMUST00000137234.1
Tmem56

transmembrane protein 56

chr4_-_148160031 0.135 ENSMUST00000057907.3
Fbxo44
F-box protein 44
chr13_-_9765137 0.122 ENSMUST00000062658.8
ENSMUST00000130151.1
ENSMUST00000110636.1
ENSMUST00000152725.1
Zmynd11



zinc finger, MYND domain containing 11



chr2_+_35622010 0.107 ENSMUST00000091010.5
Dab2ip
disabled 2 interacting protein
chr9_-_85749308 0.105 ENSMUST00000039213.8
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr5_+_65391497 0.096 ENSMUST00000031101.3
ENSMUST00000122026.1
Lias

lipoic acid synthetase

chr7_+_105640522 0.089 ENSMUST00000106785.1
ENSMUST00000106786.1
ENSMUST00000106780.1
ENSMUST00000106784.1
Timm10b



translocase of inner mitochondrial membrane 10B



chr14_+_118937925 0.061 ENSMUST00000022734.7
Dnajc3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr7_-_12818837 0.053 ENSMUST00000121215.1
ENSMUST00000108546.1
ENSMUST00000072222.7
Zfp329


zinc finger protein 329


chr16_+_87454976 0.049 ENSMUST00000119504.1
ENSMUST00000131356.1
Usp16

ubiquitin specific peptidase 16

chr16_-_34514084 0.031 ENSMUST00000089655.5
Kalrn
kalirin, RhoGEF kinase
chr7_+_105640448 0.018 ENSMUST00000058333.3
Timm10b
translocase of inner mitochondrial membrane 10B
chr7_-_143740316 0.010 ENSMUST00000119499.1
Osbpl5
oxysterol binding protein-like 5
chr5_-_65391408 0.010 ENSMUST00000057885.6
Rpl9
ribosomal protein L9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.5 1.5 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.4 2.2 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.4 1.4 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.3 1.9 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 0.9 GO:0048389 signal transduction by trans-phosphorylation(GO:0023016) limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098) mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180) kidney smooth muscle tissue development(GO:0072194)
0.3 1.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 1.1 GO:0009597 detection of virus(GO:0009597)
0.3 1.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 1.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.2 0.5 GO:0070488 neutrophil aggregation(GO:0070488)
0.2 2.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.7 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.9 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.5 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.9 GO:0036376 sodium ion export from cell(GO:0036376)
0.1 0.6 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.6 GO:0097264 self proteolysis(GO:0097264)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 3.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.3 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 2.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0021554 optic nerve development(GO:0021554)
0.0 0.7 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.2 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.0 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 1.6 GO:0033010 paranodal junction(GO:0033010)
0.2 3.0 GO:0042581 specific granule(GO:0042581)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 1.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.3 0.9 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 1.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2 1.9 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.7 GO:0097001 ceramide binding(GO:0097001)
0.1 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.9 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 2.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.8 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 1.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.4 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 1.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 3.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.5 PID_AURORA_B_PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 2.9 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 1.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.9 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.4 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)