Motif ID: Zfp282

Z-value: 0.474


Transcription factors associated with Zfp282:

Gene SymbolEntrez IDGene Name
Zfp282 ENSMUSG00000025821.9 Zfp282

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp282mm10_v2_chr6_+_47877204_478772040.133.5e-01Click!


Activity profile for motif Zfp282.

activity profile for motif Zfp282


Sorted Z-values histogram for motif Zfp282

Sorted Z-values for motif Zfp282



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp282

PNG image of the network

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Top targets:


Showing 1 to 20 of 81 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_80000292 2.958 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr14_+_75955003 2.789 ENSMUST00000050120.2
 Kctd4
potassium channel tetramerisation domain containing 4
chr18_-_35722330 2.603 ENSMUST00000133064.1
 Ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr6_-_29507946 2.465 ENSMUST00000101614.3
ENSMUST00000078112.6
 Kcp

kielin/chordin-like protein

chr9_+_34904913 2.232 ENSMUST00000045091.6
 Kirrel3
kin of IRRE like 3 (Drosophila)
chr11_+_35121126 1.862 ENSMUST00000069837.3
 Slit3
slit homolog 3 (Drosophila)
chr16_-_85803106 1.767 ENSMUST00000023610.8
 Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr7_-_28766469 1.611 ENSMUST00000085851.5
ENSMUST00000032815.4
 Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr7_+_28766747 1.588 ENSMUST00000170068.1
ENSMUST00000072965.4
 Sirt2

sirtuin 2

chr7_-_35556304 1.573 ENSMUST00000040962.5
 Nudt19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr17_-_50094277 1.466 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr14_-_70627008 1.464 ENSMUST00000110984.2
 Dmtn
dematin actin binding protein
chr9_-_105131775 1.401 ENSMUST00000035179.6
 Nudt16
nudix (nucleoside diphosphate linked moiety X)-type motif 16
chr1_+_195017399 1.339 ENSMUST00000181273.1
 A330023F24Rik
RIKEN cDNA A330023F24 gene
chr9_+_18427543 1.159 ENSMUST00000053326.9
 Gm5612
predicted gene 5612
chr4_-_40239779 1.077 ENSMUST00000037907.6
 Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_-_25005895 0.942 ENSMUST00000102858.3
ENSMUST00000080882.6
 Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr11_-_109298066 0.926 ENSMUST00000106706.1
 Rgs9
regulator of G-protein signaling 9
chr5_+_137569851 0.919 ENSMUST00000031729.8
 Tfr2
transferrin receptor 2
chr12_+_9574437 0.891 ENSMUST00000057021.7
 Osr1
odd-skipped related 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 2.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 2.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.4 2.2 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.3 1.9 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.2 1.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.5 1.6 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.3 1.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.5 1.5 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.3 1.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.4 1.4 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 1.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.3 1.1 GO:0009597 detection of virus(GO:0009597)
0.3 0.9 GO:0048389 signal transduction by trans-phosphorylation(GO:0023016) limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098) mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180) kidney smooth muscle tissue development(GO:0072194)
0.1 0.9 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.9 GO:0036376 sodium ion export from cell(GO:0036376)
0.1 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 0.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1 0.7 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.7 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.0 GO:0042581 specific granule(GO:0042581)
0.0 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.8 GO:0005604 basement membrane(GO:0005604)
0.0 1.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 1.6 GO:0033010 paranodal junction(GO:0033010)
0.4 1.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 1.9 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 1.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.2 1.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2 1.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.3 0.9 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.9 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.7 GO:0097001 ceramide binding(GO:0097001)
0.1 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0048256 flap endonuclease activity(GO:0048256)

Gene overrepresentation in C2:CP category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.4 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 1.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.6 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.5 PID_AURORA_B_PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 2.7 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 1.4 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport