Motif ID: Zfp384

Z-value: 1.271


Transcription factors associated with Zfp384:

Gene SymbolEntrez IDGene Name
Zfp384 ENSMUSG00000038346.12 Zfp384

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp384mm10_v2_chr6_+_125009261_125009317-0.152.8e-01Click!


Activity profile for motif Zfp384.

activity profile for motif Zfp384


Sorted Z-values histogram for motif Zfp384

Sorted Z-values for motif Zfp384



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp384

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 13.480 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chrX_-_60893430 8.482 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr11_+_101627942 8.474 ENSMUST00000010506.3
Rdm1
RAD52 motif 1
chr14_-_67715585 8.104 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr18_-_74207771 7.906 ENSMUST00000040188.8
ENSMUST00000177604.1
Ska1

spindle and kinetochore associated complex subunit 1

chr8_-_4779513 7.745 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr19_+_37376359 7.509 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr4_-_131838231 7.280 ENSMUST00000030741.2
ENSMUST00000105987.2
Ptpru

protein tyrosine phosphatase, receptor type, U

chr13_+_94875600 7.273 ENSMUST00000022195.10
Otp
orthopedia homolog (Drosophila)
chr2_-_26503814 7.075 ENSMUST00000028288.4
Notch1
notch 1
chr4_-_143299498 6.605 ENSMUST00000030317.7
Pdpn
podoplanin
chr17_+_85620816 6.513 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr8_-_123318553 6.495 ENSMUST00000118395.1
ENSMUST00000035495.8
Fanca

Fanconi anemia, complementation group A

chr7_-_127042420 6.349 ENSMUST00000032915.6
Kif22
kinesin family member 22
chr13_+_104229366 6.344 ENSMUST00000022227.6
Cenpk
centromere protein K
chr13_-_24761861 6.245 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr1_+_90203980 6.163 ENSMUST00000065587.4
ENSMUST00000159654.1
Ackr3

atypical chemokine receptor 3

chr2_+_5845243 6.023 ENSMUST00000127116.1
Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr7_+_80294450 5.923 ENSMUST00000163812.2
ENSMUST00000047558.7
ENSMUST00000174199.1
ENSMUST00000173824.1
ENSMUST00000174172.1
Prc1




protein regulator of cytokinesis 1




chr12_+_118846329 5.797 ENSMUST00000063918.2
Sp8
trans-acting transcription factor 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 459 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 15.8 GO:0038092 nodal signaling pathway(GO:0038092)
3.0 15.2 GO:0015671 oxygen transport(GO:0015671)
0.5 14.0 GO:0021854 hypothalamus development(GO:0021854)
2.3 11.7 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.2 10.8 GO:0006334 nucleosome assembly(GO:0006334)
0.3 10.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
3.5 10.5 GO:0097402 neuroblast migration(GO:0097402)
1.4 9.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 9.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 8.8 GO:0006270 DNA replication initiation(GO:0006270)
0.1 8.6 GO:0006342 chromatin silencing(GO:0006342)
0.8 8.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 8.3 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.4 8.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
2.0 7.9 GO:0019323 D-ribose metabolic process(GO:0006014) pentose catabolic process(GO:0019323)
0.8 7.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.5 7.3 GO:0000076 DNA replication checkpoint(GO:0000076)
2.4 7.1 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
0.7 7.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 6.9 GO:0007062 sister chromatid cohesion(GO:0007062)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 213 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 27.3 GO:0000786 nucleosome(GO:0000786)
0.3 14.8 GO:0005871 kinesin complex(GO:0005871)
0.1 13.1 GO:0044798 nuclear transcription factor complex(GO:0044798)
1.3 11.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.4 11.0 GO:0005833 hemoglobin complex(GO:0005833)
0.1 10.8 GO:0005667 transcription factor complex(GO:0005667)
0.8 9.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 8.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 8.3 GO:0000776 kinetochore(GO:0000776)
0.8 7.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.4 7.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 7.1 GO:0048786 presynaptic active zone(GO:0048786)
0.4 5.9 GO:0070938 contractile ring(GO:0070938)
0.2 5.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 5.7 GO:0001741 XY body(GO:0001741)
1.4 5.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 5.4 GO:0005844 polysome(GO:0005844)
0.3 5.3 GO:0031527 filopodium membrane(GO:0031527)
0.1 5.3 GO:0032993 protein-DNA complex(GO:0032993)
0.1 5.2 GO:0036126 sperm flagellum(GO:0036126)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 306 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 15.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
3.0 15.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 14.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 11.6 GO:0003677 DNA binding(GO:0003677)
0.4 11.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 11.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
1.1 10.6 GO:0019956 chemokine binding(GO:0019956)
0.3 10.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 9.8 GO:0001222 transcription corepressor binding(GO:0001222)
1.4 9.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.4 9.6 GO:0070410 co-SMAD binding(GO:0070410)
0.1 9.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 9.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 8.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.7 8.1 GO:0008430 selenium binding(GO:0008430)
2.6 7.9 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 7.8 GO:0051082 unfolded protein binding(GO:0051082)
2.6 7.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 7.2 GO:0042169 SH2 domain binding(GO:0042169)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 18.9 PID_PLK1_PATHWAY PLK1 signaling events
0.2 17.8 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.3 13.1 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.4 12.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 12.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.2 9.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.2 8.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 8.5 PID_ARF6_PATHWAY Arf6 signaling events
0.2 8.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.8 7.3 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.4 5.8 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.2 5.7 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 4.8 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 4.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 4.5 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 3.5 PID_E2F_PATHWAY E2F transcription factor network
0.2 3.4 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 3.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.3 PID_MYC_PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 96 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 23.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.7 17.8 REACTOME_KINESINS Genes involved in Kinesins
0.2 17.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.4 14.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.6 11.6 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.7 11.4 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.6 9.6 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.2 9.1 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 8.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.3 7.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 7.8 REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.5 7.7 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.9 7.2 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 6.9 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 6.7 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 6.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 6.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 6.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 6.1 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 5.6 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation