Motif ID: Zfp652

Z-value: 0.907


Transcription factors associated with Zfp652:

Gene SymbolEntrez IDGene Name
Zfp652 ENSMUSG00000075595.3 Zfp652

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp652mm10_v2_chr11_+_95712673_95712673-0.133.3e-01Click!


Activity profile for motif Zfp652.

activity profile for motif Zfp652


Sorted Z-values histogram for motif Zfp652

Sorted Z-values for motif Zfp652



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp652

PNG image of the network

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Top targets:


Showing 1 to 20 of 96 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_53707532 15.654 ENSMUST00000031093.3
 Cckar
cholecystokinin A receptor
chr4_-_63403330 10.571 ENSMUST00000035724.4
 Akna
AT-hook transcription factor
chr10_-_92165159 9.751 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
 Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr10_+_26229707 9.336 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr16_+_30065333 9.082 ENSMUST00000023171.7
 Hes1
hairy and enhancer of split 1 (Drosophila)
chr5_+_115908644 8.806 ENSMUST00000141101.1
 Cit
citron
chr1_-_138847579 7.729 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr6_+_83137089 7.373 ENSMUST00000121093.1
ENSMUST00000087938.4
 Rtkn

rhotekin

chr14_+_73237891 7.155 ENSMUST00000044405.6
 Lpar6
lysophosphatidic acid receptor 6
chr7_-_25788635 6.985 ENSMUST00000002677.4
ENSMUST00000085948.4
 Axl

AXL receptor tyrosine kinase

chr1_+_184034381 6.844 ENSMUST00000048655.7
 Dusp10
dual specificity phosphatase 10
chr3_+_87971071 6.662 ENSMUST00000090973.5
 Nes
nestin
chr3_+_87971129 6.661 ENSMUST00000160694.1
 Nes
nestin
chr1_-_118982551 5.990 ENSMUST00000159678.1
 Gli2
GLI-Kruppel family member GLI2
chr1_+_153665274 5.973 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr3_-_116129615 5.894 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1
chr6_+_137754529 5.638 ENSMUST00000087675.6
 Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr1_+_153665666 5.618 ENSMUST00000111814.1
ENSMUST00000111810.1
 Rgs8

regulator of G-protein signaling 8

chr6_+_124808885 5.279 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
 Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr14_+_55853997 4.921 ENSMUST00000100529.3
 Nynrin
NYN domain and retroviral integrase containing

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 20.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
5.2 15.7 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
3.0 9.1 GO:0021557 oculomotor nerve development(GO:0021557)
0.0 8.8 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.4 8.7 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
1.5 7.7 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 7.4 GO:0007266 Rho protein signal transduction(GO:0007266)
0.3 7.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
2.3 7.0 GO:0097350 neutrophil clearance(GO:0097350)
1.4 6.8 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
1.5 6.0 GO:0060032 notochord regression(GO:0060032)
0.5 5.9 GO:0061032 visceral serous pericardium development(GO:0061032)
1.4 5.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.6 4.9 GO:0015074 DNA integration(GO:0015074)
0.1 4.5 GO:0048747 muscle fiber development(GO:0048747)
0.4 4.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 4.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 4.1 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
1.3 3.9 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 3.9 GO:0007283 spermatogenesis(GO:0007283)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 15.7 GO:0043195 terminal bouton(GO:0043195)
0.2 13.3 GO:0005882 intermediate filament(GO:0005882)
0.3 12.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 11.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 10.6 GO:0001650 fibrillar center(GO:0001650)
0.2 9.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 7.0 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.5 6.0 GO:0097542 ciliary tip(GO:0097542)
1.0 4.1 GO:0043259 laminin-10 complex(GO:0043259)
0.2 3.4 GO:0031105 septin complex(GO:0031105)
0.0 3.3 GO:0000790 nuclear chromatin(GO:0000790)
0.2 3.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 3.1 GO:0002102 podosome(GO:0002102)
0.0 3.0 GO:0016607 nuclear speck(GO:0016607)
0.0 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.6 GO:0035097 histone methyltransferase complex(GO:0035097)
0.3 2.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.7 2.1 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.8 GO:0044327 dendritic spine head(GO:0044327)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 20.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.6 15.9 GO:0008432 JUN kinase binding(GO:0008432)
0.3 15.7 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
1.5 13.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 10.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.9 7.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.0 7.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.6 7.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 6.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.3 6.6 GO:0035497 cAMP response element binding(GO:0035497)
0.2 6.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
1.5 5.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 5.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.4 4.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 4.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 4.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 3.9 GO:0035014 retinoic acid binding(GO:0001972) phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 3.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 3.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 2.8 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in C2:CP category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 16.1 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 8.8 PID_RHOA_PATHWAY RhoA signaling pathway
0.2 6.8 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.2 6.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.3 5.9 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5 4.1 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.5 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 3.3 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 3.3 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.1 2.6 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 2.6 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 2.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 2.4 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 1.8 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.8 PID_ATM_PATHWAY ATM pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 20.1 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.2 15.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.4 12.1 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 8.8 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.8 7.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.3 5.9 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 5.3 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 4.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 4.1 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.6 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 1.8 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.8 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 1.3 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.0 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.9 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.8 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction