Motif ID: Zfp691

Z-value: 0.465


Transcription factors associated with Zfp691:

Gene SymbolEntrez IDGene Name
Zfp691 ENSMUSG00000045268.7 Zfp691

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp691mm10_v2_chr4_-_119174178_119174221-0.665.5e-08Click!


Activity profile for motif Zfp691.

activity profile for motif Zfp691


Sorted Z-values histogram for motif Zfp691

Sorted Z-values for motif Zfp691



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp691

PNG image of the network

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Top targets:


Showing 1 to 20 of 100 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_86732409 2.814 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr14_+_119138415 2.622 ENSMUST00000065904.3
 Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr5_+_37050854 2.038 ENSMUST00000043794.4
 Jakmip1
janus kinase and microtubule interacting protein 1
chr9_-_103761820 1.795 ENSMUST00000049452.8
 Tmem108
transmembrane protein 108
chr15_-_12592556 1.595 ENSMUST00000075317.5
 Pdzd2
PDZ domain containing 2
chr10_+_81183263 1.465 ENSMUST00000047665.6
 Dapk3
death-associated protein kinase 3
chr3_-_82074639 1.454 ENSMUST00000029635.8
 Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr8_+_72319033 1.388 ENSMUST00000067912.7
 Klf2
Kruppel-like factor 2 (lung)
chr1_+_134193432 1.304 ENSMUST00000038445.6
 Mybph
myosin binding protein H
chr9_-_58202281 1.286 ENSMUST00000163897.1
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr2_-_10130638 1.250 ENSMUST00000042290.7
 Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr2_+_181715005 1.065 ENSMUST00000071585.3
ENSMUST00000148334.1
ENSMUST00000108763.1
 Oprl1


opioid receptor-like 1


chr13_-_34130345 1.042 ENSMUST00000075774.3
 Tubb2b
tubulin, beta 2B class IIB
chr4_-_129623870 1.017 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
 Ccdc28b


coiled coil domain containing 28B


chr15_+_82252397 1.008 ENSMUST00000136948.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr8_+_69808672 0.957 ENSMUST00000036074.8
ENSMUST00000123453.1
 Gmip

Gem-interacting protein

chr10_+_81183000 0.897 ENSMUST00000178422.1
 Dapk3
death-associated protein kinase 3
chr9_+_62858085 0.857 ENSMUST00000034777.6
ENSMUST00000163820.1
 Calml4

calmodulin-like 4

chr11_-_75422586 0.837 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr8_-_22805596 0.826 ENSMUST00000163739.1
 Ap3m2
adaptor-related protein complex 3, mu 2 subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.8 2.4 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.3 1.8 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.5 1.5 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 1.4 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.3 1.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.4 1.1 GO:1904059 positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059)
0.1 1.0 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.2 0.8 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.8 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.8 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.8 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.7 GO:0001881 receptor recycling(GO:0001881)
0.2 0.6 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.2 0.6 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.5 GO:0072562 blood microparticle(GO:0072562)
0.2 1.3 GO:0005859 muscle myosin complex(GO:0005859)
0.2 0.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.8 GO:0043203 axon hillock(GO:0043203)
0.1 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0045177 apical part of cell(GO:0045177)
0.1 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 2.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 2.0 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.5 GO:0042923 neuropeptide binding(GO:0042923)
0.1 1.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.3 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 0.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.8 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.6 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.5 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.1 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.6 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 2.4 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 2.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.5 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.0 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.6 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis