Motif ID: Zfp691
Z-value: 0.465
Transcription factors associated with Zfp691:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zfp691 | ENSMUSG00000045268.7 | Zfp691 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zfp691 | mm10_v2_chr4_-_119174178_119174221 | -0.66 | 5.5e-08 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.4 | GO:0031038 | myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519) |
| 0.5 | 1.5 | GO:0099548 | trans-synaptic signaling by nitric oxide(GO:0099548) |
| 0.4 | 2.6 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.4 | 1.1 | GO:1904059 | positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059) |
| 0.3 | 1.3 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.3 | 1.8 | GO:1990416 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.2 | 1.4 | GO:0071499 | response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499) |
| 0.2 | 0.6 | GO:0032829 | regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) |
| 0.2 | 0.5 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
| 0.2 | 0.8 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.2 | 0.6 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 0.1 | 0.4 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
| 0.1 | 0.4 | GO:1902022 | ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of activation of Janus kinase activity(GO:0010533) L-lysine transport(GO:1902022) |
| 0.1 | 0.4 | GO:1904154 | trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 0.1 | 0.8 | GO:0051461 | protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 0.1 | 1.0 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
| 0.1 | 0.5 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.1 | 0.4 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.1 | 0.8 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.1 | 0.4 | GO:0070417 | cellular response to cold(GO:0070417) |
| 0.1 | 0.7 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.1 | 0.3 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.1 | 0.2 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.1 | 0.3 | GO:0097503 | sialylation(GO:0097503) |
| 0.0 | 1.3 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.6 | GO:0034312 | diol biosynthetic process(GO:0034312) |
| 0.0 | 0.5 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
| 0.0 | 0.1 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.6 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 0.3 | GO:2000348 | protein linear polyubiquitination(GO:0097039) regulation of CD40 signaling pathway(GO:2000348) |
| 0.0 | 0.8 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.0 | 0.3 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.2 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.0 | 0.4 | GO:0097186 | amelogenesis(GO:0097186) |
| 0.0 | 0.8 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
| 0.0 | 1.3 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.0 | 0.8 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.0 | 0.2 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.0 | 0.1 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.0 | 0.1 | GO:1903719 | regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) |
| 0.0 | 0.6 | GO:0006801 | superoxide metabolic process(GO:0006801) |
| 0.0 | 0.2 | GO:1903541 | regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543) |
| 0.0 | 0.6 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.0 | 0.1 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.0 | 0.7 | GO:0001881 | receptor recycling(GO:0001881) |
| 0.0 | 0.4 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.3 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.2 | 0.8 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.1 | 0.5 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.1 | 0.6 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.1 | 1.5 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.3 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.1 | 0.3 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.1 | 0.8 | GO:0043203 | axon hillock(GO:0043203) |
| 0.1 | 0.8 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.8 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 0.6 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.5 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 0.6 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 1.5 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.1 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.0 | 0.1 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.6 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
| 0.3 | 1.3 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 2.0 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.2 | 0.8 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.1 | 0.5 | GO:0035514 | DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515) |
| 0.1 | 0.8 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 1.5 | GO:0042923 | neuropeptide binding(GO:0042923) |
| 0.1 | 1.5 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.1 | 0.6 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.1 | 2.0 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 0.4 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.1 | 0.6 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
| 0.1 | 0.4 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.1 | 0.7 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.8 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.1 | 2.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.2 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.0 | 0.4 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.1 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 0.1 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.0 | 0.8 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.1 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
| 0.0 | 0.2 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.0 | 0.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 1.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.6 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 0.6 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.0 | 0.2 | GO:0004312 | fatty acid synthase activity(GO:0004312) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.0 | 0.4 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.4 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.0 | 0.8 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.8 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.4 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 2.6 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 1.0 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 0.6 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 1.5 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 0.4 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.3 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 2.0 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.6 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.7 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.4 | REACTOME_PERK_REGULATED_GENE_EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.0 | 0.8 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 1.8 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
