Motif ID: Zic3

Z-value: 0.896


Transcription factors associated with Zic3:

Gene SymbolEntrez IDGene Name
Zic3 ENSMUSG00000067860.5 Zic3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zic3mm10_v2_chrX_+_58030999_580310180.725.9e-10Click!


Activity profile for motif Zic3.

activity profile for motif Zic3


Sorted Z-values histogram for motif Zic3

Sorted Z-values for motif Zic3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zic3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_53159885 4.782 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr7_+_127800604 3.920 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr7_+_51879041 3.103 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr8_+_127064107 3.093 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr1_-_119053339 3.093 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr17_+_86963279 3.045 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr13_-_29984219 3.024 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr13_+_44729535 2.909 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr4_+_108165449 2.898 ENSMUST00000116309.3
ENSMUST00000116307.1
Echdc2

enoyl Coenzyme A hydratase domain containing 2

chr5_-_98030727 2.755 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr2_+_172550991 2.720 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chrX_+_56454871 2.715 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr6_-_56362356 2.700 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr7_+_51878967 2.668 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr4_+_108165432 2.611 ENSMUST00000052999.6
Echdc2
enoyl Coenzyme A hydratase domain containing 2
chr9_+_91378636 2.562 ENSMUST00000066384.5
Zic4
zinc finger protein of the cerebellum 4
chr1_+_135729147 2.474 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr5_+_135725713 2.462 ENSMUST00000127096.1
Por
P450 (cytochrome) oxidoreductase
chr5_+_137758133 2.455 ENSMUST00000141733.1
ENSMUST00000110985.1
Tsc22d4

TSC22 domain family, member 4

chr13_-_95891905 2.404 ENSMUST00000068603.6
Iqgap2
IQ motif containing GTPase activating protein 2
chr13_+_44730726 2.336 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr11_-_34833631 2.279 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr2_-_160872985 2.233 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chr2_-_180776900 2.217 ENSMUST00000108878.1
Bhlhe23
basic helix-loop-helix family, member e23
chr8_+_127064022 2.188 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr5_-_114273702 2.156 ENSMUST00000144050.1
ENSMUST00000044790.5
Foxn4

forkhead box N4

chr2_-_104816696 2.095 ENSMUST00000117237.1
Qser1
glutamine and serine rich 1
chr14_+_31217850 1.986 ENSMUST00000090180.2
Sema3g
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr12_-_27342696 1.968 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr11_-_100354040 1.935 ENSMUST00000173630.1
Hap1
huntingtin-associated protein 1
chr5_+_139543889 1.885 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr9_-_103480328 1.864 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr14_-_54926784 1.814 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr2_+_120629113 1.813 ENSMUST00000150912.1
ENSMUST00000180041.1
Stard9

START domain containing 9

chr4_+_141010644 1.790 ENSMUST00000071977.8
Mfap2
microfibrillar-associated protein 2
chr6_+_61180313 1.778 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr7_-_48881032 1.767 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chrX_-_108834303 1.761 ENSMUST00000101283.3
ENSMUST00000150434.1
Brwd3

bromodomain and WD repeat domain containing 3

chr8_+_127063893 1.748 ENSMUST00000162309.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr2_-_39190687 1.724 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr2_-_127482499 1.710 ENSMUST00000088538.5
Kcnip3
Kv channel interacting protein 3, calsenilin
chrX_+_161717498 1.709 ENSMUST00000061514.7
Rai2
retinoic acid induced 2
chr2_+_156840966 1.695 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr4_+_52439235 1.676 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
Smc2


structural maintenance of chromosomes 2


chr12_+_112620030 1.662 ENSMUST00000180015.1
ENSMUST00000021726.6
Adssl1

adenylosuccinate synthetase like 1

chr9_-_82975475 1.650 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr7_-_49636847 1.647 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chrY_-_1286563 1.554 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr4_-_62208426 1.525 ENSMUST00000068822.3
Zfp37
zinc finger protein 37
chr11_+_102604370 1.519 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr2_-_160872829 1.513 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr3_-_108415552 1.473 ENSMUST00000090558.3
Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chrX_+_137049586 1.419 ENSMUST00000047852.7
Fam199x
family with sequence similarity 199, X-linked
chr2_-_160872552 1.410 ENSMUST00000103111.2
Zhx3
zinc fingers and homeoboxes 3
chr14_-_73325773 1.409 ENSMUST00000022701.6
Rb1
retinoblastoma 1
chr14_-_31640878 1.397 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chr9_+_85842852 1.396 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr11_+_97030130 1.388 ENSMUST00000153482.1
Scrn2
secernin 2
chrX_+_140956892 1.378 ENSMUST00000112971.1
Atg4a
autophagy related 4A, cysteine peptidase
chr2_+_15055274 1.368 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr10_+_18845071 1.350 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr8_-_18950932 1.341 ENSMUST00000055503.5
ENSMUST00000095438.3
Xkr5

X Kell blood group precursor-related family, member 5

chr10_-_81349085 1.326 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr10_-_49788743 1.321 ENSMUST00000105483.1
ENSMUST00000105487.1
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chr15_-_99820072 1.315 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr13_-_81633119 1.311 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
Gpr98



G protein-coupled receptor 98



chr14_-_37098211 1.303 ENSMUST00000022337.9
Cdhr1
cadherin-related family member 1
chr11_-_98149551 1.290 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr5_+_115506668 1.283 ENSMUST00000067268.8
ENSMUST00000086523.3
Pxn

paxillin

chr4_+_108460000 1.283 ENSMUST00000097925.2
Zcchc11
zinc finger, CCHC domain containing 11
chr2_+_131234043 1.248 ENSMUST00000041362.5
ENSMUST00000110199.2
Mavs

mitochondrial antiviral signaling protein

chrX_+_71050160 1.225 ENSMUST00000082088.3
ENSMUST00000114629.3
Mamld1

mastermind-like domain containing 1

chr7_-_109439076 1.199 ENSMUST00000106745.2
ENSMUST00000090414.4
Stk33

serine/threonine kinase 33

chr19_+_7268296 1.193 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr8_+_4248188 1.189 ENSMUST00000110993.1
Gm14378
predicted gene 14378
chr7_-_4778141 1.160 ENSMUST00000094892.5
Il11
interleukin 11
chr2_+_127008711 1.156 ENSMUST00000110394.1
ENSMUST00000002063.8
Ap4e1

adaptor-related protein complex AP-4, epsilon 1

chr2_+_84840612 1.155 ENSMUST00000111625.1
Slc43a1
solute carrier family 43, member 1
chr14_+_54476100 1.148 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr7_-_70360593 1.124 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr11_+_72042455 1.110 ENSMUST00000021164.3
Fam64a
family with sequence similarity 64, member A
chrY_-_1245685 1.109 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr11_-_48826655 1.101 ENSMUST00000104959.1
Gm12184
predicted gene 12184
chr7_+_127800844 1.094 ENSMUST00000106271.1
ENSMUST00000138432.1
Hsd3b7

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

chr17_+_86963077 1.091 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr2_+_156840077 1.091 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr2_-_170427828 1.083 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr9_-_32344237 1.068 ENSMUST00000034533.5
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr11_+_97029925 1.058 ENSMUST00000021249.4
Scrn2
secernin 2
chr7_-_109438998 1.049 ENSMUST00000121378.1
Stk33
serine/threonine kinase 33
chrX_+_73639414 1.043 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr6_+_146577859 1.036 ENSMUST00000067404.6
ENSMUST00000111663.2
ENSMUST00000058245.4
Fgfr1op2


FGFR1 oncogene partner 2


chr3_-_102204576 1.035 ENSMUST00000159388.1
Vangl1
vang-like 1 (van gogh, Drosophila)
chr6_+_86404336 1.034 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr6_-_39725448 1.032 ENSMUST00000002487.8
Braf
Braf transforming gene
chr12_-_111813834 1.019 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr4_-_154097105 1.018 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
Trp73


transformation related protein 73


chr16_+_37011758 1.006 ENSMUST00000071452.5
ENSMUST00000054034.6
Polq

polymerase (DNA directed), theta

chr19_-_4615453 0.997 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chrY_-_1245753 0.996 ENSMUST00000154004.1
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr13_-_47105790 0.995 ENSMUST00000129352.1
Dek
DEK oncogene (DNA binding)
chr6_+_86404219 0.992 ENSMUST00000095754.3
ENSMUST00000095753.2
Tia1

cytotoxic granule-associated RNA binding protein 1

chr12_+_89812467 0.987 ENSMUST00000110133.2
ENSMUST00000110130.2
Nrxn3

neurexin III

chr19_+_46397009 0.984 ENSMUST00000118440.1
Sufu
suppressor of fused homolog (Drosophila)
chrX_+_10717390 0.984 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr6_-_146577825 0.978 ENSMUST00000032427.8
Asun
asunder, spermatogenesis regulator
chr9_-_77544870 0.977 ENSMUST00000183873.1
Lrrc1
leucine rich repeat containing 1
chr9_-_77544829 0.976 ENSMUST00000183734.1
Lrrc1
leucine rich repeat containing 1
chr6_+_86404257 0.972 ENSMUST00000095752.2
ENSMUST00000130967.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chrX_+_37126777 0.964 ENSMUST00000016553.4
Nkap
NFKB activating protein
chr17_+_14279506 0.958 ENSMUST00000024660.8
Smoc2
SPARC related modular calcium binding 2
chr2_-_20968526 0.953 ENSMUST00000141298.2
ENSMUST00000125783.2
Arhgap21

Rho GTPase activating protein 21

chr14_-_48665098 0.950 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr3_+_87930256 0.944 ENSMUST00000055984.6
Isg20l2
interferon stimulated exonuclease gene 20-like 2
chr6_-_101377342 0.937 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr19_+_46396885 0.934 ENSMUST00000039922.6
ENSMUST00000111867.2
ENSMUST00000120778.1
Sufu


suppressor of fused homolog (Drosophila)


chr19_+_6975048 0.930 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr8_-_87959560 0.928 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr14_-_34374617 0.920 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr10_-_63023847 0.914 ENSMUST00000119814.2
Hnrnph3
heterogeneous nuclear ribonucleoprotein H3
chr14_-_56811464 0.907 ENSMUST00000173954.1
Zmym5
zinc finger, MYM-type 5
chr3_+_103279293 0.895 ENSMUST00000029444.6
ENSMUST00000106860.1
Trim33

tripartite motif-containing 33

chr15_+_40655020 0.894 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr16_-_91044473 0.885 ENSMUST00000118522.1
Paxbp1
PAX3 and PAX7 binding protein 1
chr16_+_32332238 0.884 ENSMUST00000115151.3
Ubxn7
UBX domain protein 7
chr2_-_151009364 0.879 ENSMUST00000109896.1
Ninl
ninein-like
chr12_-_21373550 0.878 ENSMUST00000101551.3
Adam17
a disintegrin and metallopeptidase domain 17
chr3_+_86224665 0.873 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr12_-_21373606 0.869 ENSMUST00000064536.6
Adam17
a disintegrin and metallopeptidase domain 17
chrX_+_10717451 0.856 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr11_-_100759740 0.848 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr7_-_109438786 0.841 ENSMUST00000121748.1
Stk33
serine/threonine kinase 33
chr14_+_31001414 0.836 ENSMUST00000022476.7
Glt8d1
glycosyltransferase 8 domain containing 1
chr11_+_116280939 0.825 ENSMUST00000055872.2
Galr2
galanin receptor 2
chr13_+_96542727 0.815 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr14_+_31001383 0.805 ENSMUST00000168584.1
Glt8d1
glycosyltransferase 8 domain containing 1
chr5_+_92137896 0.802 ENSMUST00000031355.6
Uso1
USO1 vesicle docking factor
chr19_+_3767953 0.800 ENSMUST00000113970.1
Suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr11_+_79339792 0.785 ENSMUST00000108251.2
ENSMUST00000071325.2
Nf1

neurofibromatosis 1

chr2_-_122369130 0.782 ENSMUST00000151130.1
ENSMUST00000125826.1
Shf

Src homology 2 domain containing F

chr2_-_119477613 0.782 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr17_+_25786566 0.775 ENSMUST00000095500.4
Ccdc78
coiled-coil domain containing 78
chr1_+_166254095 0.774 ENSMUST00000111416.1
Ildr2
immunoglobulin-like domain containing receptor 2
chr4_+_131873608 0.759 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr11_+_96789118 0.757 ENSMUST00000018810.3
Cbx1
chromobox 1
chr2_-_146511899 0.756 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr6_+_48395652 0.750 ENSMUST00000077093.4
Krba1
KRAB-A domain containing 1
chr14_-_55560340 0.749 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr9_+_46012810 0.745 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr11_-_72266596 0.735 ENSMUST00000021161.6
ENSMUST00000140167.1
Slc13a5

solute carrier family 13 (sodium-dependent citrate transporter), member 5

chr14_-_56811716 0.732 ENSMUST00000039812.9
ENSMUST00000111285.2
Zmym5

zinc finger, MYM-type 5

chr4_-_129614254 0.730 ENSMUST00000106037.2
ENSMUST00000179209.1
Dcdc2b

doublecortin domain containing 2b

chr18_-_67724560 0.713 ENSMUST00000120934.1
ENSMUST00000025420.7
ENSMUST00000122412.1
Ptpn2


protein tyrosine phosphatase, non-receptor type 2


chr10_+_81137953 0.709 ENSMUST00000117956.1
Zbtb7a
zinc finger and BTB domain containing 7a
chr9_-_123678873 0.709 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr11_+_96789213 0.697 ENSMUST00000079702.3
Cbx1
chromobox 1
chr17_+_4994904 0.694 ENSMUST00000092723.4
ENSMUST00000115797.2
Arid1b

AT rich interactive domain 1B (SWI-like)

chr6_+_48395586 0.692 ENSMUST00000114571.1
ENSMUST00000114572.3
ENSMUST00000031815.5
Krba1


KRAB-A domain containing 1


chr12_+_83632208 0.690 ENSMUST00000048155.9
ENSMUST00000182618.1
ENSMUST00000183154.1
ENSMUST00000182036.1
ENSMUST00000182347.1
Rbm25




RNA binding motif protein 25




chr2_+_174110340 0.687 ENSMUST00000044415.9
Npepl1
aminopeptidase-like 1
chr8_-_47289394 0.667 ENSMUST00000079195.5
Stox2
storkhead box 2
chr11_+_96789149 0.666 ENSMUST00000093943.3
Cbx1
chromobox 1
chr11_-_70687917 0.663 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr10_-_127522428 0.662 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr11_-_109473220 0.661 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_-_105787544 0.651 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr11_+_60537978 0.651 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chrX_+_7762652 0.643 ENSMUST00000077680.3
ENSMUST00000079542.6
ENSMUST00000115679.1
ENSMUST00000137467.1
Tfe3



transcription factor E3



chr8_+_4243264 0.637 ENSMUST00000110996.1
Map2k7
mitogen-activated protein kinase kinase 7
chr5_-_115436508 0.635 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr5_+_93093428 0.633 ENSMUST00000074733.7
Sept11
septin 11
chr10_+_39732364 0.631 ENSMUST00000164763.1
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr19_-_4839286 0.629 ENSMUST00000037246.5
Ccs
copper chaperone for superoxide dismutase
chr12_-_102704896 0.602 ENSMUST00000178697.1
ENSMUST00000046518.5
Itpk1

inositol 1,3,4-triphosphate 5/6 kinase

chr1_-_58586191 0.599 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chrX_+_163909132 0.596 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr10_-_78487842 0.591 ENSMUST00000069431.4
Gm9978
predicted gene 9978
chr11_+_115900125 0.591 ENSMUST00000142089.1
ENSMUST00000131566.1
Smim5

small integral membrane protein 5

chrX_+_52791179 0.584 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr4_+_43632185 0.584 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr1_+_191906743 0.582 ENSMUST00000044954.6
Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr14_+_25607797 0.579 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chrX_+_71364901 0.578 ENSMUST00000132837.1
Mtmr1
myotubularin related protein 1
chr6_+_7844806 0.575 ENSMUST00000040159.4
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chrX_+_57053549 0.573 ENSMUST00000114751.2
ENSMUST00000088652.5
Htatsf1

HIV TAT specific factor 1

chr18_-_84951477 0.572 ENSMUST00000025547.2
Timm21
tranlocase of inner mitochondrial membrane 21
chr12_+_84316830 0.570 ENSMUST00000045931.10
Zfp410
zinc finger protein 410
chr11_+_67078293 0.570 ENSMUST00000108689.1
ENSMUST00000165221.1
ENSMUST00000007301.7
Myh3


myosin, heavy polypeptide 3, skeletal muscle, embryonic


chr7_+_90442729 0.554 ENSMUST00000061767.4
ENSMUST00000107206.1
Crebzf

CREB/ATF bZIP transcription factor

chr17_+_25951472 0.551 ENSMUST00000181174.1
D630044L22Rik
RIKEN cDNA gene D630044L22 gene
chr15_-_78803015 0.549 ENSMUST00000164826.1
Card10
caspase recruitment domain family, member 10
chr17_+_34593388 0.549 ENSMUST00000174532.1
Pbx2
pre B cell leukemia homeobox 2
chr11_+_53519871 0.548 ENSMUST00000120878.2
Sept8
septin 8
chr17_-_32788284 0.548 ENSMUST00000159086.2
Zfp871
zinc finger protein 871
chr2_-_168590315 0.540 ENSMUST00000109184.1
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr10_-_115587739 0.539 ENSMUST00000020350.8
Lgr5
leucine rich repeat containing G protein coupled receptor 5
chr12_+_112760652 0.537 ENSMUST00000063888.3
Pld4
phospholipase D family, member 4
chr13_+_6548154 0.537 ENSMUST00000021611.8
Pitrm1
pitrilysin metallepetidase 1
chr1_-_64121456 0.536 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr9_+_46012822 0.533 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0055099 response to high density lipoprotein particle(GO:0055099)
1.4 1.4 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
1.2 7.0 GO:0003383 apical constriction(GO:0003383)
0.9 2.7 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.8 3.1 GO:0060032 notochord regression(GO:0060032)
0.7 5.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.7 2.0 GO:0060023 soft palate development(GO:0060023)
0.6 2.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.6 2.5 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.6 1.8 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.5 3.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.5 1.9 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.5 1.4 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.4 1.2 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.4 5.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 1.9 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.4 0.4 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.3 0.9 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 1.8 GO:0002934 desmosome organization(GO:0002934)
0.3 1.5 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223) hard palate development(GO:0060022)
0.3 3.0 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 0.9 GO:0003195 tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 1.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 1.4 GO:0051697 protein delipidation(GO:0051697)
0.3 2.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 0.8 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.3 3.8 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.3 0.8 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.3 2.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 1.0 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 0.7 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.2 1.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.2 1.9 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 0.7 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.2 1.1 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 0.4 GO:0006167 AMP biosynthetic process(GO:0006167)
0.2 1.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 1.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 1.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.8 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2 0.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 0.6 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 1.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 1.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 2.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 0.7 GO:0015744 succinate transport(GO:0015744)
0.2 0.5 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2 0.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 1.0 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.2 0.7 GO:0010288 response to lead ion(GO:0010288)
0.2 0.7 GO:0006545 glycine biosynthetic process(GO:0006545)
0.2 4.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 1.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.2 0.7 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 2.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 0.7 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.2 0.5 GO:0014916 regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793)
0.2 1.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 2.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 2.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 1.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.0 GO:2000301 myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 1.5 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.5 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.1 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.8 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.3 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 1.0 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 1.8 GO:0030220 platelet formation(GO:0030220)
0.1 0.4 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.6 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.4 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:2001016 heparan sulfate proteoglycan catabolic process(GO:0030200) positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.1 0.8 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 1.7 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.9 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.3 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.4 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.2 GO:2000195 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) negative regulation of female gonad development(GO:2000195)
0.1 4.5 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 1.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 3.1 GO:1901998 toxin transport(GO:1901998)
0.1 5.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.6 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 0.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 2.0 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 0.5 GO:0061525 hindgut development(GO:0061525)
0.1 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.6 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.2 GO:1904938 dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
0.0 0.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 1.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 2.5 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.8 GO:0045056 transcytosis(GO:0045056)
0.0 0.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.6 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 1.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.5 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.3 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.0 1.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 1.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.6 GO:0031529 ruffle organization(GO:0031529)
0.0 0.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:1903800 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 1.5 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.6 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.5 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.8 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.6 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.3 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.4 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.0 0.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 1.0 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 1.4 GO:0051225 spindle assembly(GO:0051225)
0.0 1.0 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0090292 nuclear migration along microfilament(GO:0031022) nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 2.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691) negative regulation of interleukin-1 production(GO:0032692)
0.0 0.7 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.7 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 0.6 GO:0042254 ribosome biogenesis(GO:0042254)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.0 GO:0033269 internode region of axon(GO:0033269)
0.3 3.0 GO:0097165 nuclear stress granule(GO:0097165)
0.3 1.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.3 2.1 GO:0001940 male pronucleus(GO:0001940)
0.3 1.4 GO:0035189 Rb-E2F complex(GO:0035189)
0.3 4.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 3.1 GO:0097542 ciliary tip(GO:0097542)
0.2 1.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 1.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 4.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 2.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.7 GO:0000796 condensin complex(GO:0000796)
0.2 0.7 GO:0070552 BRISC complex(GO:0070552)
0.1 1.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.8 GO:0098536 deuterosome(GO:0098536)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.6 GO:0032982 myosin filament(GO:0032982)
0.1 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.3 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.4 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 2.7 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 3.7 GO:0005938 cell cortex(GO:0005938)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 1.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 1.9 GO:0045177 apical part of cell(GO:0045177)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.8 5.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.6 2.5 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.5 2.3 GO:0043515 kinetochore binding(GO:0043515)
0.4 5.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.4 2.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 1.8 GO:0070051 fibrinogen binding(GO:0070051)
0.3 4.1 GO:0005522 profilin binding(GO:0005522)
0.3 2.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3 1.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 1.2 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.7 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 1.9 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.2 0.7 GO:0097677 STAT family protein binding(GO:0097677)
0.2 0.7 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 1.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 2.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 1.1 GO:0045545 syndecan binding(GO:0045545)
0.2 1.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 0.8 GO:0004966 galanin receptor activity(GO:0004966)
0.2 0.6 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.5 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.5 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.2 1.5 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 2.4 GO:0016805 dipeptidase activity(GO:0016805)
0.2 0.7 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 0.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 1.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 0.9 GO:0097001 ceramide binding(GO:0097001)
0.1 7.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.0 GO:0000150 recombinase activity(GO:0000150)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.4 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 2.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 1.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.6 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 3.6 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.1 1.6 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.1 3.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 2.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.1 7.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.3 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.6 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 8.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 4.5 GO:0001047 core promoter binding(GO:0001047)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 1.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.6 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 2.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.0 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.6 GO:0008017 microtubule binding(GO:0008017)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0003774 motor activity(GO:0003774)
0.0 0.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.7 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 2.5 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.8 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 3.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 7.0 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 4.4 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 6.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 3.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.3 PID_IGF1_PATHWAY IGF1 pathway
0.1 5.0 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 0.7 PID_ALK2_PATHWAY ALK2 signaling events
0.1 2.6 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.1 2.1 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 1.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.2 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.3 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.2 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.4 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.7 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.0 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.8 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.0 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 4.8 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 7.0 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 6.1 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 3.0 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 2.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 3.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.2 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 0.7 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.5 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.0 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.7 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.7 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.8 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.0 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.2 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.3 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.2 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac