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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ATF5

Z-value: 0.83

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Transcription factors associated with ATF5

Gene Symbol Gene ID Gene Info
ATF5
ENSG00000169136.4 activating transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF5hg19_v2_chr19_+_50431959_50431998-0.522.9e-01Click!

Activity profile of ATF5 motif

Sorted Z-values of ATF5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_52612705 0.74 ENST00000434986.2
BCAS1
breast carcinoma amplified sequence 1
chr14_+_32546145 0.63 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr2_-_188419078 0.41 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr19_+_42773371 0.38 ENST00000571942.2
CIC
capicua transcriptional repressor
chr14_+_32547434 0.37 ENST00000556191.1
ENST00000554090.1
ARHGAP5
Rho GTPase activating protein 5
chr18_-_19748379 0.36 ENST00000579431.1
GATA6-AS1
GATA6 antisense RNA 1 (head to head)
chr8_-_95449155 0.36 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr20_-_52612468 0.34 ENST00000422805.1
BCAS1
breast carcinoma amplified sequence 1
chrX_-_19983260 0.34 ENST00000340625.3
CXorf23
chromosome X open reading frame 23
chr14_+_32546274 0.31 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr2_-_114514181 0.27 ENST00000409342.1
SLC35F5
solute carrier family 35, member F5
chr3_-_101232019 0.26 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr3_+_119814070 0.26 ENST00000469070.1
RP11-18H7.1
RP11-18H7.1
chr6_-_100016492 0.26 ENST00000369217.4
ENST00000369220.4
ENST00000482541.2
CCNC
cyclin C
chr1_+_61869748 0.26 ENST00000357977.5
NFIA
nuclear factor I/A
chr8_+_95731904 0.26 ENST00000522422.1
DPY19L4
dpy-19-like 4 (C. elegans)
chr12_-_52967600 0.25 ENST00000549343.1
ENST00000305620.2
KRT74
keratin 74
chr1_-_205053645 0.24 ENST00000367167.3
TMEM81
transmembrane protein 81
chr2_-_188419200 0.23 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr1_+_223354486 0.22 ENST00000446145.1
RP11-239E10.3
RP11-239E10.3
chr12_-_72057571 0.22 ENST00000548100.1
ZFC3H1
zinc finger, C3H1-type containing
chr16_-_72128270 0.21 ENST00000426362.2
TXNL4B
thioredoxin-like 4B
chr6_-_88411911 0.21 ENST00000257787.5
AKIRIN2
akirin 2
chr12_+_32655048 0.21 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr9_+_19230433 0.21 ENST00000434457.2
ENST00000602925.1
DENND4C
DENN/MADD domain containing 4C
chrX_+_123095546 0.20 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chrX_-_44402231 0.20 ENST00000378045.4
FUNDC1
FUN14 domain containing 1
chr6_+_87865262 0.20 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr11_-_117102768 0.20 ENST00000532301.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr6_-_100016527 0.19 ENST00000523985.1
ENST00000518714.1
ENST00000520371.1
CCNC
cyclin C
chr3_-_183145873 0.19 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF2L2
MCF.2 cell line derived transforming sequence-like 2
chr14_+_50065459 0.19 ENST00000318317.4
LRR1
leucine rich repeat protein 1
chr12_-_100656134 0.19 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr21_-_35773370 0.19 ENST00000410005.1
AP000322.54
chromosome 21 open reading frame 140
chr6_-_100016678 0.19 ENST00000523799.1
ENST00000520429.1
CCNC
cyclin C
chr7_-_127672146 0.18 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr1_-_46598371 0.18 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr4_-_84376953 0.18 ENST00000510985.1
ENST00000295488.3
HELQ
helicase, POLQ-like
chr12_-_72057638 0.18 ENST00000552037.1
ENST00000378743.3
ZFC3H1
zinc finger, C3H1-type containing
chrX_+_123095860 0.18 ENST00000428941.1
STAG2
stromal antigen 2
chr5_-_39219705 0.18 ENST00000351578.6
FYB
FYN binding protein
chr8_+_95732095 0.17 ENST00000414645.2
DPY19L4
dpy-19-like 4 (C. elegans)
chrX_+_123095890 0.16 ENST00000435215.1
STAG2
stromal antigen 2
chr3_-_88108192 0.16 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr1_+_101361626 0.16 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr6_+_76599809 0.16 ENST00000430435.1
MYO6
myosin VI
chr17_+_38337491 0.16 ENST00000538981.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr8_+_67344710 0.15 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr4_+_2800722 0.15 ENST00000508385.1
SH3BP2
SH3-domain binding protein 2
chr9_-_6007787 0.14 ENST00000399933.3
ENST00000381461.2
ENST00000513355.2
KIAA2026
KIAA2026
chr17_+_38219063 0.14 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA
thyroid hormone receptor, alpha
chrX_+_123095155 0.14 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chr11_-_6462210 0.14 ENST00000265983.3
HPX
hemopexin
chrX_-_47489244 0.14 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr3_+_193853927 0.14 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr14_+_50065376 0.13 ENST00000298288.6
LRR1
leucine rich repeat protein 1
chr2_+_173724771 0.13 ENST00000538974.1
ENST00000540783.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr6_+_114178512 0.13 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_+_206137237 0.13 ENST00000468509.1
ENST00000367129.2
FAM72A
family with sequence similarity 72, member A
chr8_+_79428539 0.13 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr10_+_104178946 0.12 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr11_-_108408895 0.12 ENST00000443411.1
ENST00000533052.1
EXPH5
exophilin 5
chr4_-_122085469 0.12 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr3_+_112930306 0.12 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr14_-_36988882 0.12 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr7_-_100061869 0.11 ENST00000332375.3
C7orf61
chromosome 7 open reading frame 61
chr5_+_50678921 0.11 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr16_+_57438679 0.11 ENST00000219244.4
CCL17
chemokine (C-C motif) ligand 17
chr2_-_87248975 0.11 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chr5_+_110559312 0.11 ENST00000508074.1
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr12_-_115121962 0.11 ENST00000349155.2
TBX3
T-box 3
chr15_+_63481668 0.11 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B
RAB8B, member RAS oncogene family
chr1_-_27930102 0.11 ENST00000247087.5
ENST00000374011.2
AHDC1
AT hook, DNA binding motif, containing 1
chr4_+_84377115 0.11 ENST00000295491.4
ENST00000507019.1
MRPS18C
mitochondrial ribosomal protein S18C
chr19_+_41509851 0.11 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr17_+_44790515 0.10 ENST00000576346.1
NSF
N-ethylmaleimide-sensitive factor
chr16_-_72127456 0.10 ENST00000562153.1
TXNL4B
thioredoxin-like 4B
chr14_-_54420133 0.10 ENST00000559501.1
ENST00000558984.1
BMP4
bone morphogenetic protein 4
chr1_+_160321120 0.10 ENST00000424754.1
NCSTN
nicastrin
chr5_-_39219641 0.10 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYB
FYN binding protein
chr3_+_19988736 0.10 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr18_-_812517 0.10 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr11_+_27076764 0.10 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr15_+_78556428 0.10 ENST00000394855.3
ENST00000489435.2
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr3_+_101504200 0.09 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr12_+_32655110 0.09 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr5_+_82767487 0.09 ENST00000343200.5
ENST00000342785.4
VCAN
versican
chr8_+_145294015 0.09 ENST00000544576.1
MROH1
maestro heat-like repeat family member 1
chr22_+_37678505 0.09 ENST00000402997.1
ENST00000405206.3
CYTH4
cytohesin 4
chr18_-_53089723 0.09 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr2_+_217498105 0.09 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr16_+_31271274 0.08 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr8_+_38677850 0.08 ENST00000518809.1
ENST00000520611.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr10_+_111765562 0.08 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr18_-_812231 0.08 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr12_-_120884175 0.08 ENST00000546954.1
TRIAP1
TP53 regulated inhibitor of apoptosis 1
chr4_+_84377198 0.08 ENST00000507349.1
ENST00000509970.1
ENST00000505719.1
MRPS18C
mitochondrial ribosomal protein S18C
chr5_+_82767284 0.08 ENST00000265077.3
VCAN
versican
chr19_-_44285401 0.08 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr16_+_28943260 0.08 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19
CD19 molecule
chr19_-_15090488 0.08 ENST00000594383.1
ENST00000598504.1
ENST00000597262.1
SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chrX_-_13835461 0.08 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr16_-_57513657 0.07 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr10_-_7453445 0.07 ENST00000379713.3
ENST00000397167.1
ENST00000397160.3
SFMBT2
Scm-like with four mbt domains 2
chr5_+_175223313 0.07 ENST00000359546.4
CPLX2
complexin 2
chr19_-_38916839 0.07 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4
RAS guanyl releasing protein 4
chr3_-_182698381 0.07 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr3_+_19988885 0.07 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr2_+_191334212 0.07 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr3_-_127441406 0.07 ENST00000487473.1
ENST00000484451.1
MGLL
monoglyceride lipase
chr12_-_54778444 0.07 ENST00000551771.1
ZNF385A
zinc finger protein 385A
chr12_+_120884222 0.07 ENST00000551765.1
ENST00000229384.5
GATC
glutamyl-tRNA(Gln) amidotransferase, subunit C
chr8_+_37553261 0.07 ENST00000331569.4
ZNF703
zinc finger protein 703
chr6_-_31514333 0.07 ENST00000376151.4
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr17_+_41005283 0.07 ENST00000592999.1
AOC3
amine oxidase, copper containing 3
chr3_+_19988566 0.07 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr2_-_225434538 0.07 ENST00000409096.1
CUL3
cullin 3
chr7_-_115670792 0.07 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr2_-_214016314 0.06 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr16_-_30537839 0.06 ENST00000380412.5
ZNF768
zinc finger protein 768
chr17_+_33474826 0.06 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B
unc-45 homolog B (C. elegans)
chr5_+_125967372 0.06 ENST00000357147.3
C5orf48
chromosome 5 open reading frame 48
chr5_+_82767583 0.06 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN
versican
chr11_+_124735282 0.06 ENST00000397801.1
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr22_-_26875345 0.06 ENST00000398141.1
HPS4
Hermansky-Pudlak syndrome 4
chr8_+_100025476 0.06 ENST00000355155.1
ENST00000357162.2
ENST00000358544.2
ENST00000395996.1
ENST00000441350.2
VPS13B
vacuolar protein sorting 13 homolog B (yeast)
chr11_-_18956556 0.06 ENST00000302797.3
MRGPRX1
MAS-related GPR, member X1
chr14_-_21567009 0.06 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr2_-_197036289 0.05 ENST00000263955.4
STK17B
serine/threonine kinase 17b
chr12_+_104680659 0.05 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1
thioredoxin reductase 1
chr19_+_15160130 0.05 ENST00000427043.3
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr17_+_55055466 0.05 ENST00000262288.3
ENST00000572710.1
ENST00000575395.1
SCPEP1
serine carboxypeptidase 1
chrX_+_131157609 0.05 ENST00000496850.1
MST4
Serine/threonine-protein kinase MST4
chr9_+_131902283 0.05 ENST00000436883.1
ENST00000414510.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chrX_-_122866874 0.05 ENST00000245838.8
ENST00000355725.4
THOC2
THO complex 2
chr14_-_39901618 0.05 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr7_-_115670804 0.05 ENST00000320239.7
TFEC
transcription factor EC
chr9_+_109625378 0.04 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr3_-_99569821 0.04 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr4_+_48807155 0.04 ENST00000504654.1
OCIAD1
OCIA domain containing 1
chr10_-_99531709 0.04 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr14_+_96968707 0.04 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA
poly(A) polymerase alpha
chr2_+_189839046 0.04 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr11_-_33891362 0.04 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr22_-_26875631 0.04 ENST00000402105.3
HPS4
Hermansky-Pudlak syndrome 4
chr2_-_209118974 0.04 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chrX_+_133930798 0.04 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr9_+_2621798 0.04 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr19_-_18366182 0.04 ENST00000355502.3
PDE4C
phosphodiesterase 4C, cAMP-specific
chr15_-_90222610 0.04 ENST00000300055.5
PLIN1
perilipin 1
chr14_-_21566731 0.04 ENST00000360947.3
ZNF219
zinc finger protein 219
chr19_+_55795493 0.03 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr12_-_1920886 0.03 ENST00000536846.2
ENST00000538027.2
ENST00000538450.1
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr19_-_10491234 0.03 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chr2_-_190927447 0.03 ENST00000260950.4
MSTN
myostatin
chr16_-_72127550 0.03 ENST00000268483.3
TXNL4B
thioredoxin-like 4B
chr1_-_22109484 0.03 ENST00000529637.1
USP48
ubiquitin specific peptidase 48
chr1_+_206579736 0.03 ENST00000439126.1
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr12_-_24103954 0.03 ENST00000441133.2
ENST00000545921.1
SOX5
SRY (sex determining region Y)-box 5
chr9_-_116065551 0.03 ENST00000297894.5
RNF183
ring finger protein 183
chr15_-_90222642 0.03 ENST00000430628.2
PLIN1
perilipin 1
chrX_+_122318318 0.03 ENST00000371251.1
ENST00000371256.5
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr19_-_10491130 0.03 ENST00000530829.1
ENST00000529370.1
TYK2
tyrosine kinase 2
chr1_-_151804222 0.03 ENST00000392697.3
RORC
RAR-related orphan receptor C
chr5_+_137203465 0.03 ENST00000239926.4
MYOT
myotilin
chr5_+_34757309 0.03 ENST00000397449.1
RAI14
retinoic acid induced 14
chr5_+_158527630 0.03 ENST00000523301.1
RP11-175K6.1
RP11-175K6.1
chr17_+_33474860 0.03 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr8_+_107738343 0.03 ENST00000521592.1
OXR1
oxidation resistance 1
chr3_+_23958470 0.03 ENST00000434031.2
ENST00000413699.1
ENST00000456530.2
RPL15
ribosomal protein L15
chr3_-_23958402 0.03 ENST00000415901.2
ENST00000416026.2
ENST00000412028.1
ENST00000388759.3
ENST00000437230.1
NKIRAS1
NFKB inhibitor interacting Ras-like 1
chr8_+_107738240 0.02 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr1_+_36023370 0.02 ENST00000356090.4
ENST00000373243.2
NCDN
neurochondrin
chr12_-_12491608 0.02 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr1_-_11863571 0.02 ENST00000376583.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr17_-_46691990 0.02 ENST00000576562.1
HOXB8
homeobox B8
chr11_+_57310114 0.02 ENST00000527972.1
ENST00000399154.2
SMTNL1
smoothelin-like 1
chr14_+_79746249 0.02 ENST00000428277.2
NRXN3
neurexin 3
chr5_-_132200477 0.02 ENST00000296875.2
GDF9
growth differentiation factor 9
chr1_-_54872059 0.02 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr16_-_72206034 0.02 ENST00000537465.1
ENST00000237353.10
PMFBP1
polyamine modulated factor 1 binding protein 1
chr17_+_33914424 0.02 ENST00000590432.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr7_-_78400364 0.02 ENST00000535697.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_156887027 0.02 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr14_+_79745746 0.02 ENST00000281127.7
NRXN3
neurexin 3
chr1_-_11863171 0.02 ENST00000376592.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr5_+_132009675 0.02 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr12_-_54778244 0.02 ENST00000549937.1
ZNF385A
zinc finger protein 385A
chr18_-_24128496 0.02 ENST00000417602.1
KCTD1
potassium channel tetramerization domain containing 1
chr22_-_36236623 0.02 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_+_16083123 0.02 ENST00000510393.1
ENST00000430076.1
FBLIM1
filamin binding LIM protein 1
chr16_+_30075463 0.02 ENST00000562168.1
ENST00000569545.1
ALDOA
aldolase A, fructose-bisphosphate
chr11_+_28724129 0.01 ENST00000513853.1
RP11-115J23.1
RP11-115J23.1
chr5_-_156390230 0.01 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr12_-_54778471 0.01 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A
zinc finger protein 385A
chr1_-_202776392 0.01 ENST00000235790.4
KDM5B
lysine (K)-specific demethylase 5B
chr7_+_73498118 0.01 ENST00000336180.2
LIMK1
LIM domain kinase 1
chr1_-_156460391 0.01 ENST00000360595.3
MEF2D
myocyte enhancer factor 2D
chr12_-_54652060 0.01 ENST00000552562.1
CBX5
chromobox homolog 5
chr15_+_77287426 0.01 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:2000974 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 0.4 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0017055 female courtship behavior(GO:0008050) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.1 GO:0061151 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887) thyroid hormone binding(GO:0070324)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine