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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ATF6

Z-value: 0.88

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Transcription factors associated with ATF6

Gene Symbol Gene ID Gene Info
ATF6
ENSG00000118217.5 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF6hg19_v2_chr1_+_161736072_1617360930.602.1e-01Click!

Activity profile of ATF6 motif

Sorted Z-values of ATF6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_38445011 0.60 ENST00000464265.1
ENST00000399102.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr8_+_9009296 0.55 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr7_+_12726623 0.46 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chr11_-_14521349 0.42 ENST00000534234.1
COPB1
coatomer protein complex, subunit beta 1
chr21_-_38445297 0.41 ENST00000430792.1
ENST00000399103.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr2_+_223725723 0.37 ENST00000535678.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr4_+_39640787 0.35 ENST00000532680.1
RP11-539G18.2
RP11-539G18.2
chr22_-_39548443 0.33 ENST00000401405.3
CBX7
chromobox homolog 7
chr14_+_65016620 0.33 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr19_-_48673465 0.32 ENST00000598938.1
LIG1
ligase I, DNA, ATP-dependent
chr12_+_1100710 0.30 ENST00000589132.1
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr1_-_94344686 0.30 ENST00000528680.1
DNTTIP2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr16_+_53164833 0.29 ENST00000564845.1
CHD9
chromodomain helicase DNA binding protein 9
chr17_+_18684563 0.29 ENST00000476139.1
TVP23B
trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
chr2_-_55276320 0.29 ENST00000357376.3
RTN4
reticulon 4
chr21_+_38445539 0.28 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr10_+_35416223 0.28 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr11_-_46638720 0.26 ENST00000326737.3
HARBI1
harbinger transposase derived 1
chr9_+_114393581 0.26 ENST00000313525.3
DNAJC25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr1_+_185126291 0.25 ENST00000367500.4
SWT1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr1_+_185126207 0.25 ENST00000367501.3
SWT1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr11_+_20409227 0.24 ENST00000437750.2
PRMT3
protein arginine methyltransferase 3
chr14_-_35183755 0.24 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr7_+_12726474 0.24 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ARL4A
ADP-ribosylation factor-like 4A
chr5_+_94890840 0.24 ENST00000504763.1
ARSK
arylsulfatase family, member K
chr17_-_15466742 0.24 ENST00000584811.1
ENST00000419890.2
TVP23C
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
chr17_-_77967433 0.23 ENST00000571872.1
TBC1D16
TBC1 domain family, member 16
chr17_-_15466850 0.23 ENST00000438826.3
ENST00000225576.3
ENST00000519970.1
ENST00000518321.1
ENST00000428082.2
ENST00000522212.2
TVP23C
TVP23C-CDRT4
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TVP23C-CDRT4 readthrough
chr10_-_22292675 0.23 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr7_+_92861653 0.22 ENST00000251739.5
ENST00000305866.5
ENST00000544910.1
ENST00000541136.1
ENST00000458530.1
ENST00000535481.1
ENST00000317751.6
CCDC132
coiled-coil domain containing 132
chr4_-_4544061 0.22 ENST00000507908.1
STX18
syntaxin 18
chr22_-_38577782 0.22 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr1_-_185126037 0.22 ENST00000367506.5
ENST00000367504.3
TRMT1L
tRNA methyltransferase 1 homolog (S. cerevisiae)-like
chr5_+_78532003 0.21 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr15_+_23255242 0.21 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr1_-_211752073 0.20 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr4_-_99850243 0.20 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E
eukaryotic translation initiation factor 4E
chr9_-_77643307 0.20 ENST00000376834.3
ENST00000376830.3
C9orf41
chromosome 9 open reading frame 41
chr2_-_98612379 0.19 ENST00000425805.2
TMEM131
transmembrane protein 131
chr9_+_114393634 0.19 ENST00000556107.1
ENST00000374294.3
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr17_+_49337881 0.19 ENST00000225298.7
UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr6_-_86353510 0.19 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr14_-_35183886 0.19 ENST00000298159.6
CFL2
cofilin 2 (muscle)
chr7_+_97910962 0.19 ENST00000539286.1
BRI3
brain protein I3
chr3_-_156272924 0.19 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr1_+_222791417 0.19 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
MIA3
melanoma inhibitory activity family, member 3
chr8_+_109455830 0.19 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr19_-_52227221 0.18 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr20_+_37590942 0.18 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr3_-_101395936 0.18 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr7_-_86849836 0.18 ENST00000455575.1
TMEM243
transmembrane protein 243, mitochondrial
chr11_-_35547151 0.18 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr7_-_27169801 0.18 ENST00000511914.1
HOXA4
homeobox A4
chr3_-_49933249 0.18 ENST00000434765.1
MST1R
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr19_+_10527449 0.18 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr3_-_139108463 0.18 ENST00000512242.1
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr4_-_169931393 0.18 ENST00000504480.1
ENST00000306193.3
CBR4
carbonyl reductase 4
chrX_-_119693745 0.17 ENST00000371323.2
CUL4B
cullin 4B
chr4_+_141264597 0.17 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr3_+_3168600 0.17 ENST00000251607.6
ENST00000339437.6
ENST00000280591.6
ENST00000420393.1
TRNT1
tRNA nucleotidyl transferase, CCA-adding, 1
chr22_-_39096981 0.17 ENST00000427389.1
JOSD1
Josephin domain containing 1
chr6_+_26204825 0.17 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr3_+_170075436 0.17 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKIL
SKI-like oncogene
chr1_-_193028426 0.17 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr22_-_39096925 0.17 ENST00000456626.1
ENST00000412832.1
JOSD1
Josephin domain containing 1
chr7_-_100493744 0.17 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chrX_+_102862834 0.17 ENST00000372627.5
ENST00000243286.3
TCEAL3
transcription elongation factor A (SII)-like 3
chr15_-_50978965 0.17 ENST00000560955.1
ENST00000313478.7
TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr8_+_29953163 0.16 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr14_+_64970662 0.16 ENST00000556965.1
ENST00000554015.1
ZBTB1
zinc finger and BTB domain containing 1
chr9_-_77643189 0.16 ENST00000376837.3
C9orf41
chromosome 9 open reading frame 41
chr19_-_39523165 0.16 ENST00000509137.2
ENST00000292853.4
FBXO27
F-box protein 27
chr12_-_76953453 0.16 ENST00000549570.1
OSBPL8
oxysterol binding protein-like 8
chr2_-_197036289 0.16 ENST00000263955.4
STK17B
serine/threonine kinase 17b
chr19_-_13710678 0.16 ENST00000592864.1
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr20_+_44421137 0.16 ENST00000415790.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr3_+_184529948 0.16 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr12_+_110562135 0.16 ENST00000361948.4
ENST00000552912.1
ENST00000242591.5
ENST00000546374.1
IFT81
intraflagellar transport 81 homolog (Chlamydomonas)
chr1_+_110527308 0.16 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr6_+_151773583 0.16 ENST00000545879.1
C6orf211
chromosome 6 open reading frame 211
chr2_+_223726281 0.16 ENST00000413316.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr11_-_35547277 0.16 ENST00000527605.1
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr3_-_150264272 0.15 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr2_+_118846008 0.15 ENST00000245787.4
INSIG2
insulin induced gene 2
chr14_+_64970427 0.15 ENST00000553583.1
ZBTB1
zinc finger and BTB domain containing 1
chr12_+_50497784 0.15 ENST00000548814.1
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr7_+_116593536 0.15 ENST00000417919.1
ST7
suppression of tumorigenicity 7
chr2_+_216946589 0.15 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chr3_+_184529929 0.15 ENST00000287546.4
ENST00000437079.3
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_-_193028621 0.15 ENST00000367455.4
ENST00000367454.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr10_+_27444268 0.15 ENST00000375940.4
ENST00000342386.6
MASTL
microtubule associated serine/threonine kinase-like
chr3_+_49236910 0.15 ENST00000452691.2
ENST00000366429.2
CCDC36
coiled-coil domain containing 36
chr9_-_123476612 0.15 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr11_+_20409070 0.15 ENST00000331079.6
PRMT3
protein arginine methyltransferase 3
chr2_-_182521823 0.15 ENST00000410087.3
ENST00000409440.3
CERKL
ceramide kinase-like
chr20_-_44420507 0.14 ENST00000243938.4
WFDC3
WAP four-disulfide core domain 3
chr15_+_96869165 0.14 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr6_+_159290917 0.14 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr20_-_34638841 0.14 ENST00000565493.1
LINC00657
long intergenic non-protein coding RNA 657
chr6_-_90062543 0.14 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr3_-_156877997 0.14 ENST00000295926.3
CCNL1
cyclin L1
chr7_-_98467543 0.14 ENST00000345589.4
TMEM130
transmembrane protein 130
chr3_-_197024965 0.14 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr3_+_184530173 0.14 ENST00000453056.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr2_+_219745020 0.14 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr7_-_6746474 0.14 ENST00000394917.3
ENST00000405858.1
ENST00000342651.5
ZNF12
zinc finger protein 12
chr8_-_38126635 0.14 ENST00000529359.1
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
chr5_-_78809950 0.14 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr7_-_98467629 0.13 ENST00000339375.4
TMEM130
transmembrane protein 130
chr4_+_128982416 0.13 ENST00000326639.6
LARP1B
La ribonucleoprotein domain family, member 1B
chr7_-_86849883 0.13 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr7_+_6522922 0.13 ENST00000601673.1
FLJ20306
CDNA FLJ20306 fis, clone HEP06881; Putative uncharacterized protein FLJ20306; Uncharacterized protein
chr9_-_88356789 0.13 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
AGTPBP1
ATP/GTP binding protein 1
chr10_-_27444143 0.13 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr4_+_85504075 0.13 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr17_+_42977062 0.13 ENST00000410006.2
ENST00000357776.2
ENST00000410027.1
CCDC103
coiled-coil domain containing 103
chr1_+_87170577 0.13 ENST00000482504.1
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr19_-_44097188 0.13 ENST00000594374.1
L34079.2
L34079.2
chr5_+_122110691 0.13 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2
sorting nexin 2
chr9_-_123476719 0.13 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chrX_-_100914781 0.12 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
ARMCX2
armadillo repeat containing, X-linked 2
chr3_-_197024394 0.12 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr11_-_28129656 0.12 ENST00000263181.6
KIF18A
kinesin family member 18A
chr12_+_1100449 0.12 ENST00000360905.4
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr2_-_40006289 0.12 ENST00000260619.6
ENST00000454352.2
THUMPD2
THUMP domain containing 2
chr8_+_109455845 0.12 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr16_+_19729586 0.12 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQCK
IQ motif containing K
chr14_+_57857262 0.12 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr2_+_183580954 0.12 ENST00000264065.7
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr8_+_98656693 0.12 ENST00000519934.1
MTDH
metadherin
chr17_-_49337392 0.12 ENST00000376381.2
ENST00000586178.1
MBTD1
mbt domain containing 1
chr12_-_49463620 0.12 ENST00000550675.1
RHEBL1
Ras homolog enriched in brain like 1
chr11_+_58910295 0.12 ENST00000420244.1
FAM111A
family with sequence similarity 111, member A
chr13_-_36920615 0.12 ENST00000494062.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr2_-_40006357 0.12 ENST00000505747.1
THUMPD2
THUMP domain containing 2
chr1_-_113498616 0.12 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr12_+_1100370 0.12 ENST00000543086.3
ENST00000546231.2
ENST00000397203.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr3_-_121468602 0.11 ENST00000340645.5
GOLGB1
golgin B1
chr15_+_76135622 0.11 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
UBE2Q2
ubiquitin-conjugating enzyme E2Q family member 2
chrX_-_100872911 0.11 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
ARMCX6
armadillo repeat containing, X-linked 6
chr19_-_42759300 0.11 ENST00000222329.4
ERF
Ets2 repressor factor
chr17_+_6554971 0.11 ENST00000391428.2
C17orf100
chromosome 17 open reading frame 100
chr8_+_29952914 0.11 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr19_-_9811347 0.11 ENST00000585964.1
ENST00000457674.2
ENST00000590544.1
ZNF812
zinc finger protein 812
chr2_+_242254507 0.11 ENST00000391973.2
SEPT2
septin 2
chr4_+_25235597 0.11 ENST00000264864.6
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr1_-_113498943 0.11 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr5_-_99870890 0.11 ENST00000499025.1
CTD-2001C12.1
CTD-2001C12.1
chr6_-_86352982 0.11 ENST00000369622.3
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr13_+_114238997 0.11 ENST00000538138.1
ENST00000375370.5
TFDP1
transcription factor Dp-1
chr17_+_30348024 0.11 ENST00000327564.7
ENST00000584368.1
ENST00000394713.3
ENST00000341671.7
LRRC37B
leucine rich repeat containing 37B
chr5_+_99871004 0.11 ENST00000312637.4
FAM174A
family with sequence similarity 174, member A
chr13_-_49107303 0.11 ENST00000344532.3
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr3_+_52740094 0.11 ENST00000602728.1
SPCS1
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chrX_-_101397433 0.11 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr18_-_12377001 0.11 ENST00000590811.1
AFG3L2
AFG3-like AAA ATPase 2
chr22_-_39548511 0.11 ENST00000434260.1
CBX7
chromobox homolog 7
chr8_-_17104099 0.11 ENST00000524358.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr19_+_5904866 0.11 ENST00000339485.3
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chr13_+_53226963 0.10 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SUGT1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr3_-_129158850 0.10 ENST00000503197.1
ENST00000249910.1
ENST00000429544.2
ENST00000507208.1
MBD4
methyl-CpG binding domain protein 4
chr6_+_159291090 0.10 ENST00000367073.4
ENST00000608817.1
C6orf99
chromosome 6 open reading frame 99
chr5_-_114961858 0.10 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2
TMED7
TICAM2
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr12_+_117176113 0.10 ENST00000319176.7
RNFT2
ring finger protein, transmembrane 2
chrX_+_100663243 0.10 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr3_-_121468513 0.10 ENST00000494517.1
ENST00000393667.3
GOLGB1
golgin B1
chr1_-_78149041 0.10 ENST00000414381.1
ENST00000370798.1
ZZZ3
zinc finger, ZZ-type containing 3
chr12_+_56661033 0.10 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr2_-_211036051 0.10 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L
KAT8 regulatory NSL complex subunit 1-like
chr5_+_34656450 0.10 ENST00000514527.1
RAI14
retinoic acid induced 14
chr8_-_98290087 0.10 ENST00000322128.3
TSPYL5
TSPY-like 5
chr8_+_97657531 0.10 ENST00000519900.1
ENST00000517742.1
CPQ
carboxypeptidase Q
chr1_-_78148324 0.10 ENST00000370801.3
ENST00000433749.1
ZZZ3
zinc finger, ZZ-type containing 3
chrX_+_24167828 0.10 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
ZFX
zinc finger protein, X-linked
chr3_+_3168692 0.09 ENST00000402675.1
ENST00000413000.1
TRNT1
tRNA nucleotidyl transferase, CCA-adding, 1
chr11_-_57417405 0.09 ENST00000524669.1
ENST00000300022.3
YPEL4
yippee-like 4 (Drosophila)
chr13_-_36920420 0.09 ENST00000438666.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr7_-_98467489 0.09 ENST00000416379.2
TMEM130
transmembrane protein 130
chr17_+_33914424 0.09 ENST00000590432.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr17_+_4046964 0.09 ENST00000573984.1
CYB5D2
cytochrome b5 domain containing 2
chr4_+_128982490 0.09 ENST00000394288.3
ENST00000432347.2
ENST00000264584.5
ENST00000441387.1
ENST00000427266.1
ENST00000354456.3
LARP1B
La ribonucleoprotein domain family, member 1B
chr10_-_31320840 0.09 ENST00000375311.1
ZNF438
zinc finger protein 438
chr10_-_74856608 0.09 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr7_+_30811004 0.09 ENST00000265299.6
FAM188B
family with sequence similarity 188, member B
chr2_+_242254679 0.09 ENST00000428282.1
ENST00000360051.3
SEPT2
septin 2
chr11_-_113746212 0.09 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
USP28
ubiquitin specific peptidase 28
chrX_+_134478706 0.09 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
ZNF449
zinc finger protein 449
chr15_+_30844183 0.09 ENST00000333156.5
ENST00000562783.1
GOLGA8Q
golgin A8 family, member Q
chr18_-_46987000 0.09 ENST00000442713.2
ENST00000269445.6
DYM
dymeclin
chr4_-_54930790 0.09 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr11_+_61717842 0.09 ENST00000449131.2
BEST1
bestrophin 1
chr8_-_144099795 0.09 ENST00000522060.1
ENST00000517833.1
ENST00000502167.2
ENST00000518831.1
RP11-273G15.2
RP11-273G15.2
chr10_+_89622870 0.09 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr5_+_34656529 0.08 ENST00000513974.1
ENST00000512629.1
RAI14
retinoic acid induced 14
chrX_-_128977364 0.08 ENST00000371064.3
ZDHHC9
zinc finger, DHHC-type containing 9
chr6_+_116692102 0.08 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr15_-_23414193 0.08 ENST00000558241.1
RP11-467N20.5
Protein LOC440233
chr5_-_56247935 0.08 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
MIER3
mesoderm induction early response 1, family member 3
chr14_+_105190514 0.08 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr9_+_6758109 0.08 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.1 0.3 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.2 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.2 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961) calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.3 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 0.2 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.0 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 1.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.4 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0039008 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.0 GO:1902230 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.1 GO:1903121 negative regulation of ribosome biogenesis(GO:0090071) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.3 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.2 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.4 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0007135 meiosis II(GO:0007135)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.0 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
0.0 0.0 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0075341 host cell PML body(GO:0075341)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.4 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.0 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0044423 virion(GO:0019012) virion part(GO:0044423)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.2 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.1 GO:0031896 vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.0 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.0 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters