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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CEBPG

Z-value: 1.97

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Transcription factors associated with CEBPG

Gene Symbol Gene ID Gene Info
CEBPG
ENSG00000153879.4 CCAAT enhancer binding protein gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPGhg19_v2_chr19_+_33865218_33865254-0.266.2e-01Click!

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_22766766 5.39 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr11_-_18270182 4.42 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr11_+_18287801 4.33 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr11_+_18287721 4.31 ENST00000356524.4
SAA1
serum amyloid A1
chr1_-_47655686 3.32 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr6_+_31895467 3.09 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_-_153321301 2.84 ENST00000368739.3
PGLYRP4
peptidoglycan recognition protein 4
chr6_+_31895480 2.79 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr11_-_18258342 2.74 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr2_-_113594279 1.90 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr19_-_6720686 1.87 ENST00000245907.6
C3
complement component 3
chr12_+_72058130 1.62 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr6_-_133055815 1.59 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr6_-_133055896 1.54 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr19_-_6670128 1.53 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr9_+_130911723 1.40 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr3_-_4793274 1.24 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr11_-_102668879 1.16 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr19_-_4540486 1.09 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr9_+_130911770 1.04 ENST00000372998.1
LCN2
lipocalin 2
chr22_-_30901637 0.99 ENST00000381982.3
ENST00000255858.7
ENST00000540456.1
ENST00000392772.2
SEC14L4
SEC14-like 4 (S. cerevisiae)
chr5_-_121413974 0.78 ENST00000231004.4
LOX
lysyl oxidase
chr14_-_23292596 0.74 ENST00000554741.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_+_39703112 0.74 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr17_-_79895097 0.66 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr10_+_26986582 0.65 ENST00000376215.5
ENST00000376203.5
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr12_+_27849378 0.60 ENST00000310791.2
REP15
RAB15 effector protein
chr7_-_112635675 0.56 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr2_-_191885686 0.54 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr17_+_812872 0.54 ENST00000576252.1
RP11-676J12.7
Uncharacterized protein
chr17_-_79895154 0.54 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1
pyrroline-5-carboxylate reductase 1
chr22_-_42765174 0.51 ENST00000432473.1
ENST00000412060.1
ENST00000424852.1
Z83851.1
Z83851.1
chr19_+_49497121 0.48 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr12_-_95510743 0.48 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr11_-_33913708 0.48 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr19_+_49496705 0.47 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr19_+_49496782 0.47 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr1_+_165864800 0.46 ENST00000469256.2
UCK2
uridine-cytidine kinase 2
chr17_+_4699439 0.45 ENST00000270586.3
PSMB6
proteasome (prosome, macropain) subunit, beta type, 6
chr19_-_49496557 0.45 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr3_-_148939598 0.44 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr6_+_31895254 0.44 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr6_+_37897735 0.43 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr21_+_33671264 0.43 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr2_-_216300784 0.42 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr21_+_33671160 0.41 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr21_+_34775181 0.41 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr20_+_361261 0.41 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chr14_-_70263979 0.40 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr20_-_48782639 0.39 ENST00000435301.2
RP11-112L6.3
RP11-112L6.3
chr3_+_157154578 0.39 ENST00000295927.3
PTX3
pentraxin 3, long
chr7_-_14026063 0.36 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr21_+_43619796 0.36 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr1_-_243326612 0.35 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr17_-_39769005 0.33 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chrX_-_100129128 0.33 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr21_-_32119551 0.33 ENST00000333892.2
KRTAP21-2
keratin associated protein 21-2
chr2_-_175711978 0.31 ENST00000409089.2
CHN1
chimerin 1
chrX_+_47082408 0.30 ENST00000518022.1
ENST00000276052.6
CDK16
cyclin-dependent kinase 16
chr5_+_125759140 0.30 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr12_+_53846612 0.29 ENST00000551104.1
PCBP2
poly(rC) binding protein 2
chr21_-_35899113 0.28 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr15_+_67813406 0.28 ENST00000342683.4
C15orf61
chromosome 15 open reading frame 61
chr7_-_107968999 0.27 ENST00000456431.1
NRCAM
neuronal cell adhesion molecule
chr12_-_57039739 0.26 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr6_+_31895287 0.25 ENST00000447952.2
C2
complement component 2
chr9_+_117085336 0.24 ENST00000259396.8
ENST00000538816.1
ORM1
orosomucoid 1
chr17_+_7477040 0.24 ENST00000581384.1
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr19_+_45394477 0.24 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr3_-_120400960 0.23 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr1_+_165864821 0.23 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr5_+_125758813 0.23 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chrX_+_46937745 0.23 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN
regucalcin
chr3_-_157221128 0.22 ENST00000392833.2
ENST00000362010.2
VEPH1
ventricular zone expressed PH domain-containing 1
chr7_-_83824449 0.22 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr14_+_45366472 0.21 ENST00000325192.3
C14orf28
chromosome 14 open reading frame 28
chr5_+_49962772 0.21 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr7_+_137761199 0.21 ENST00000411726.2
AKR1D1
aldo-keto reductase family 1, member D1
chr4_-_119274121 0.20 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr10_+_18629628 0.18 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr12_-_71551652 0.17 ENST00000546561.1
TSPAN8
tetraspanin 8
chr5_+_36152091 0.17 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr9_+_130860810 0.17 ENST00000433501.1
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr4_+_74269956 0.17 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB
albumin
chr12_-_10605929 0.16 ENST00000347831.5
ENST00000359151.3
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr22_-_31364187 0.16 ENST00000215862.4
ENST00000397641.3
MORC2
MORC family CW-type zinc finger 2
chr20_+_361890 0.16 ENST00000449710.1
ENST00000422053.2
TRIB3
tribbles pseudokinase 3
chr7_-_8276508 0.16 ENST00000401396.1
ENST00000317367.5
ICA1
islet cell autoantigen 1, 69kDa
chrX_-_73512411 0.15 ENST00000602576.1
ENST00000429124.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr3_+_186435065 0.15 ENST00000287611.2
ENST00000265023.4
KNG1
kininogen 1
chr1_-_168698433 0.15 ENST00000367817.3
DPT
dermatopontin
chr11_-_72504681 0.15 ENST00000538536.1
ENST00000543304.1
ENST00000540587.1
ENST00000334805.6
STARD10
StAR-related lipid transfer (START) domain containing 10
chr1_+_111770294 0.15 ENST00000474304.2
CHI3L2
chitinase 3-like 2
chr19_-_36822595 0.15 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
LINC00665
long intergenic non-protein coding RNA 665
chr5_-_146258205 0.15 ENST00000394413.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chrX_-_73512358 0.14 ENST00000602776.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr5_-_146258291 0.14 ENST00000394411.4
ENST00000453001.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr11_+_60048053 0.13 ENST00000337908.4
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr17_-_76124711 0.13 ENST00000306591.7
ENST00000590602.1
TMC6
transmembrane channel-like 6
chr1_+_158901329 0.12 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr18_+_33767473 0.12 ENST00000261326.5
MOCOS
molybdenum cofactor sulfurase
chr1_+_196743912 0.12 ENST00000367425.4
CFHR3
complement factor H-related 3
chr1_-_161277210 0.12 ENST00000491222.2
MPZ
myelin protein zero
chr19_-_39805976 0.12 ENST00000248668.4
LRFN1
leucine rich repeat and fibronectin type III domain containing 1
chr4_-_111120132 0.12 ENST00000506625.1
ELOVL6
ELOVL fatty acid elongase 6
chr10_-_14596140 0.12 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr10_+_17272608 0.11 ENST00000421459.2
VIM
vimentin
chr2_-_112614424 0.11 ENST00000427997.1
ANAPC1
anaphase promoting complex subunit 1
chr1_+_75594119 0.11 ENST00000294638.5
LHX8
LIM homeobox 8
chr4_+_185909970 0.11 ENST00000505053.1
RP11-386B13.4
RP11-386B13.4
chr19_-_36822551 0.10 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr1_+_111770232 0.10 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chrX_-_153775047 0.09 ENST00000433845.1
ENST00000439227.1
G6PD
glucose-6-phosphate dehydrogenase
chr11_-_40315640 0.09 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr21_-_37852359 0.09 ENST00000399137.1
ENST00000399135.1
CLDN14
claudin 14
chr12_-_71551868 0.09 ENST00000247829.3
TSPAN8
tetraspanin 8
chr1_-_114430169 0.09 ENST00000393316.3
BCL2L15
BCL2-like 15
chr7_-_14026123 0.09 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr1_+_172389821 0.08 ENST00000367727.4
C1orf105
chromosome 1 open reading frame 105
chr5_+_125758865 0.08 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr11_-_72504637 0.08 ENST00000536377.1
ENST00000359373.5
STARD10
ARAP1
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_+_43238061 0.08 ENST00000307275.3
ENST00000585340.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr11_+_60048129 0.08 ENST00000355131.3
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr3_-_148939835 0.08 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr12_+_53835508 0.08 ENST00000551003.1
ENST00000549068.1
ENST00000549740.1
ENST00000546581.1
ENST00000549581.1
ENST00000541275.1
PRR13
PCBP2
proline rich 13
poly(rC) binding protein 2
chr3_-_190580404 0.08 ENST00000442080.1
GMNC
geminin coiled-coil domain containing
chr12_-_57522813 0.07 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr12_+_53846594 0.07 ENST00000550192.1
PCBP2
poly(rC) binding protein 2
chr4_+_184020398 0.07 ENST00000403733.3
ENST00000378925.3
WWC2
WW and C2 domain containing 2
chr16_+_72088376 0.07 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr17_+_2699697 0.06 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr7_-_121944491 0.06 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr13_-_72441315 0.06 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr4_+_175839506 0.06 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM29
ADAM metallopeptidase domain 29
chr7_-_144435985 0.06 ENST00000549981.1
TPK1
thiamin pyrophosphokinase 1
chr1_-_179112173 0.05 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr22_-_50523760 0.05 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr2_+_218994002 0.05 ENST00000428565.1
CXCR2
chemokine (C-X-C motif) receptor 2
chrX_-_73511908 0.05 ENST00000455395.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr12_+_53835383 0.05 ENST00000429243.2
PRR13
proline rich 13
chr4_+_175839551 0.04 ENST00000404450.4
ENST00000514159.1
ADAM29
ADAM metallopeptidase domain 29
chr3_-_49726486 0.04 ENST00000449682.2
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr4_-_111119804 0.04 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr20_-_60294804 0.04 ENST00000317652.1
RP11-429E11.3
Uncharacterized protein
chr9_+_115913222 0.04 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr19_+_2476116 0.03 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr6_-_27799305 0.03 ENST00000357549.2
HIST1H4K
histone cluster 1, H4k
chr17_+_57287228 0.03 ENST00000578922.1
ENST00000300917.5
SMG8
SMG8 nonsense mediated mRNA decay factor
chr2_+_47454054 0.03 ENST00000426892.1
AC106869.2
AC106869.2
chr2_+_226265364 0.03 ENST00000272907.6
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr19_-_40971667 0.02 ENST00000263368.4
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr3_+_73110810 0.02 ENST00000533473.1
EBLN2
endogenous Bornavirus-like nucleoprotein 2
chr12_-_54758251 0.02 ENST00000267015.3
ENST00000551809.1
GPR84
G protein-coupled receptor 84
chr2_-_183291741 0.02 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr19_-_1155118 0.02 ENST00000590998.1
SBNO2
strawberry notch homolog 2 (Drosophila)
chr13_-_36788718 0.02 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr3_+_186330712 0.02 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr5_-_135701164 0.02 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
TRPC7
transient receptor potential cation channel, subfamily C, member 7
chr19_+_6887571 0.01 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr1_-_179112189 0.01 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr11_-_124806297 0.01 ENST00000298251.4
HEPACAM
hepatic and glial cell adhesion molecule
chr22_-_30867973 0.01 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr2_+_113825547 0.01 ENST00000341010.2
ENST00000337569.3
IL1F10
interleukin 1 family, member 10 (theta)
chr16_-_57219721 0.01 ENST00000562406.1
ENST00000568671.1
ENST00000567044.1
FAM192A
family with sequence similarity 192, member A
chr1_+_111770278 0.01 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr4_+_71600144 0.01 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr1_-_1711508 0.01 ENST00000378625.1
NADK
NAD kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 GO:1990637 response to prolactin(GO:1990637)
0.9 2.8 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.6 1.9 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.5 2.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 5.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 1.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3 1.4 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.3 1.9 GO:0031622 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.2 14.1 GO:0006953 acute-phase response(GO:0006953)
0.2 3.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.7 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 1.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.5 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.4 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.4 GO:0001878 response to yeast(GO:0001878)
0.1 0.7 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.2 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.3 GO:0045113 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.2 GO:1903625 negative regulation of sperm motility(GO:1901318) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 1.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.3 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0031638 zymogen activation(GO:0031638)
0.0 0.6 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 15.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.4 GO:0097255 R2TP complex(GO:0097255)
0.1 8.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 3.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.6 3.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 15.8 GO:0042056 chemoattractant activity(GO:0042056)
0.3 2.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 0.8 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 1.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 6.3 GO:0001848 complement binding(GO:0001848)
0.2 1.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 1.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 7.8 PID IL27 PATHWAY IL27-mediated signaling events
0.2 5.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.3 PID MYC PATHWAY C-MYC pathway
0.0 1.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.3 8.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 3.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling