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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for DBX2_HLX

Z-value: 0.60

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Transcription factors associated with DBX2_HLX

Gene Symbol Gene ID Gene Info
DBX2
ENSG00000185610.6 developing brain homeobox 2
HLX
ENSG00000136630.11 H2.0 like homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HLXhg19_v2_chr1_+_221054584_2210545840.758.5e-02Click!

Activity profile of DBX2_HLX motif

Sorted Z-values of DBX2_HLX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_35013217 0.56 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr4_-_89442940 0.45 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chrX_+_3189861 0.43 ENST00000457435.1
ENST00000420429.2
CXorf28
chromosome X open reading frame 28
chr9_-_95055923 0.41 ENST00000430417.1
IARS
isoleucyl-tRNA synthetase
chr9_+_67977438 0.40 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr16_+_53412368 0.37 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr12_+_41136144 0.37 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr7_-_64023441 0.37 ENST00000309683.6
ZNF680
zinc finger protein 680
chr22_-_29107919 0.37 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr11_-_26593779 0.32 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr9_-_21482312 0.31 ENST00000448696.3
IFNE
interferon, epsilon
chr1_+_117963209 0.31 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr13_-_86373536 0.30 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chrX_+_77166172 0.30 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr2_+_161993465 0.30 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr1_-_168464875 0.29 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr3_+_38537960 0.28 ENST00000453767.1
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr5_+_67588312 0.27 ENST00000519025.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_-_100356551 0.27 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_-_8263538 0.26 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr4_+_95128748 0.25 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_-_112993808 0.24 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr8_+_42396274 0.24 ENST00000438528.3
SMIM19
small integral membrane protein 19
chr2_+_172309634 0.24 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr14_-_36990061 0.24 ENST00000546983.1
NKX2-1
NK2 homeobox 1
chr5_+_147691979 0.24 ENST00000274565.4
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr8_-_27695552 0.24 ENST00000522944.1
ENST00000301905.4
PBK
PDZ binding kinase
chr7_+_13141010 0.24 ENST00000443947.1
AC011288.2
AC011288.2
chr4_-_100356291 0.24 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_-_52859046 0.23 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr16_-_3350614 0.23 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr5_+_102200948 0.23 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr7_-_84122033 0.23 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr9_-_3469181 0.23 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr12_-_10573149 0.23 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
KLRC3
killer cell lectin-like receptor subfamily C, member 3
chr2_-_17981462 0.22 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr10_-_115904361 0.22 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr12_-_10282742 0.22 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr7_+_116654958 0.21 ENST00000449366.1
ST7
suppression of tumorigenicity 7
chr4_-_118006697 0.20 ENST00000310754.4
TRAM1L1
translocation associated membrane protein 1-like 1
chr5_+_115177178 0.20 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr16_-_28937027 0.20 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr11_-_26593677 0.19 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chrX_+_150565038 0.19 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_-_67142710 0.19 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr18_+_61445205 0.19 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_224544572 0.19 ENST00000366857.5
ENST00000366856.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chr9_+_125133315 0.18 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_42358742 0.18 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr1_+_234765057 0.18 ENST00000429269.1
LINC00184
long intergenic non-protein coding RNA 184
chr1_+_76251912 0.18 ENST00000370826.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr2_-_98972468 0.18 ENST00000454230.1
AC092675.3
Uncharacterized protein
chr11_-_559377 0.17 ENST00000486629.1
C11orf35
chromosome 11 open reading frame 35
chr1_-_54411255 0.17 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr8_-_71157595 0.17 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr17_+_17685422 0.17 ENST00000395774.1
RAI1
retinoic acid induced 1
chr1_+_84630574 0.17 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_-_22018966 0.17 ENST00000599906.1
ENST00000354959.4
ZNF43
zinc finger protein 43
chr12_-_10022735 0.17 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr14_+_55494323 0.17 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr10_-_28571015 0.17 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr9_+_125132803 0.17 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_76461249 0.17 ENST00000551524.1
NAP1L1
nucleosome assembly protein 1-like 1
chr1_+_81771806 0.16 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr1_-_160549235 0.16 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr4_+_75174180 0.16 ENST00000413830.1
EPGN
epithelial mitogen
chr1_+_152730499 0.16 ENST00000368773.1
KPRP
keratinocyte proline-rich protein
chrX_-_73072534 0.16 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr15_+_75970672 0.16 ENST00000435356.1
AC105020.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr4_+_74301880 0.16 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr6_+_153552455 0.16 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr3_+_138340067 0.16 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr2_+_183982255 0.15 ENST00000455063.1
NUP35
nucleoporin 35kDa
chr14_+_55493920 0.15 ENST00000395472.2
ENST00000555846.1
SOCS4
suppressor of cytokine signaling 4
chr16_-_47493041 0.15 ENST00000565940.2
ITFG1
integrin alpha FG-GAP repeat containing 1
chr6_-_52859968 0.15 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chr2_+_103089756 0.15 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr6_+_114178512 0.14 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr9_+_125133467 0.14 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr19_+_9296279 0.14 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr12_+_64798095 0.14 ENST00000332707.5
XPOT
exportin, tRNA
chr15_-_75748143 0.14 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3A
SIN3 transcription regulator family member A
chr15_+_92006567 0.14 ENST00000554333.1
RP11-661P17.1
RP11-661P17.1
chr17_+_68047418 0.14 ENST00000586373.1
ENST00000588782.1
LINC01028
long intergenic non-protein coding RNA 1028
chr7_+_129932974 0.13 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4
carboxypeptidase A4
chr2_+_211342400 0.13 ENST00000417946.1
ENST00000518043.1
ENST00000523702.1
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr5_+_179135246 0.13 ENST00000508787.1
CANX
calnexin
chr11_+_100784231 0.13 ENST00000531183.1
ARHGAP42
Rho GTPase activating protein 42
chr20_-_55934878 0.13 ENST00000543500.1
MTRNR2L3
MT-RNR2-like 3
chr8_-_42396185 0.13 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr2_+_201242941 0.13 ENST00000449647.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr12_+_80838126 0.13 ENST00000266688.5
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr10_-_99030395 0.13 ENST00000355366.5
ENST00000371027.1
ARHGAP19
Rho GTPase activating protein 19
chr1_-_204183071 0.12 ENST00000308302.3
GOLT1A
golgi transport 1A
chr1_-_186365908 0.12 ENST00000598663.1
AL596220.1
Uncharacterized protein
chr5_+_67588391 0.12 ENST00000523872.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_+_160370344 0.12 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr2_+_120687335 0.12 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr12_+_147052 0.12 ENST00000594563.1
AC026369.1
Uncharacterized protein
chr6_+_26087509 0.12 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr9_-_5833027 0.12 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr11_-_124670550 0.12 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr7_-_99716914 0.12 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr2_+_109204909 0.12 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_29001711 0.12 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr7_-_140482926 0.12 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr1_+_84630645 0.12 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr18_+_48918368 0.12 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
RP11-267C16.1
chr3_-_20053741 0.12 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chr3_+_82035289 0.12 ENST00000470263.1
ENST00000494340.1
RP11-260O18.1
RP11-260O18.1
chr12_-_76817036 0.11 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr5_+_54455946 0.11 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr5_+_95066823 0.11 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr19_-_44388116 0.11 ENST00000587539.1
ZNF404
zinc finger protein 404
chr8_-_133637624 0.11 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr2_+_191221240 0.11 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr20_+_19738300 0.11 ENST00000432334.1
RP1-122P22.2
RP1-122P22.2
chr2_+_149402989 0.11 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr16_-_28634874 0.11 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr14_-_92247032 0.11 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB
catsper channel auxiliary subunit beta
chr4_+_159131630 0.11 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr19_-_3557570 0.11 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr4_+_56815102 0.11 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr2_-_87248975 0.11 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chr11_-_111649074 0.11 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr4_+_41540160 0.11 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr1_-_152779104 0.11 ENST00000606576.1
ENST00000368768.1
LCE1C
late cornified envelope 1C
chr17_+_1674982 0.10 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr13_+_41363581 0.10 ENST00000338625.4
SLC25A15
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chr8_+_107630340 0.10 ENST00000497705.1
OXR1
oxidation resistance 1
chr10_+_91061712 0.10 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr19_-_19739321 0.10 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr14_+_60558627 0.10 ENST00000317623.4
ENST00000391611.2
ENST00000406854.1
ENST00000406949.1
PCNXL4
pecanex-like 4 (Drosophila)
chr4_+_139694701 0.10 ENST00000502606.1
RP11-98O2.1
RP11-98O2.1
chr15_+_66585950 0.10 ENST00000525109.1
DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chr1_-_154178803 0.10 ENST00000368525.3
C1orf189
chromosome 1 open reading frame 189
chr17_-_60142609 0.10 ENST00000397786.2
MED13
mediator complex subunit 13
chr2_+_87135076 0.10 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chrX_-_138724677 0.10 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr11_+_17281900 0.10 ENST00000530527.1
NUCB2
nucleobindin 2
chr4_-_185275104 0.10 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr1_+_62439037 0.10 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr19_+_50016610 0.10 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr17_+_67498538 0.10 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr16_+_24549014 0.10 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr3_+_44916098 0.10 ENST00000296125.4
TGM4
transglutaminase 4
chr4_+_48833183 0.10 ENST00000503016.1
OCIAD1
OCIA domain containing 1
chr13_-_45048386 0.09 ENST00000472477.1
TSC22D1
TSC22 domain family, member 1
chr4_+_123161120 0.09 ENST00000446180.1
KIAA1109
KIAA1109
chr10_-_74283694 0.09 ENST00000398763.4
ENST00000418483.2
ENST00000489666.2
MICU1
mitochondrial calcium uptake 1
chr1_-_108743471 0.09 ENST00000569674.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr12_-_8218997 0.09 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr7_-_22862406 0.09 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr7_+_39773160 0.09 ENST00000340510.4
LINC00265
long intergenic non-protein coding RNA 265
chr16_+_14802801 0.09 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr19_+_42212526 0.09 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
CEA
CEACAM5
Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chr1_+_196788887 0.09 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chrX_-_30871004 0.09 ENST00000378928.1
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr1_+_212475148 0.09 ENST00000537030.3
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr22_+_46476192 0.09 ENST00000443490.1
FLJ27365
hsa-mir-4763
chr19_+_21579908 0.09 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493
zinc finger protein 493
chr12_-_100656134 0.09 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr4_+_186990298 0.09 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr7_-_7575477 0.09 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr11_-_26593649 0.09 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr8_-_54752406 0.09 ENST00000520188.1
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chrX_-_77225135 0.09 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr10_-_116444371 0.09 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr5_+_68860949 0.09 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr11_-_7950209 0.08 ENST00000309838.2
OR10A6
olfactory receptor, family 10, subfamily A, member 6
chr6_+_55192267 0.08 ENST00000340465.2
GFRAL
GDNF family receptor alpha like
chr4_+_109571740 0.08 ENST00000361564.4
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr17_+_29664830 0.08 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr8_+_120885949 0.08 ENST00000523492.1
ENST00000286234.5
DEPTOR
DEP domain containing MTOR-interacting protein
chr2_+_29320571 0.08 ENST00000401605.1
ENST00000401617.2
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr16_+_15489603 0.08 ENST00000568766.1
ENST00000287594.7
RP11-1021N1.1
MPV17L
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chrX_-_73061339 0.08 ENST00000602863.1
XIST
X inactive specific transcript (non-protein coding)
chr3_-_123512688 0.08 ENST00000475616.1
MYLK
myosin light chain kinase
chr8_+_62200509 0.08 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1
clavesin 1
chr2_+_169312350 0.08 ENST00000305747.6
CERS6
ceramide synthase 6
chr5_+_136070614 0.08 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr5_-_74162739 0.08 ENST00000513277.1
FAM169A
family with sequence similarity 169, member A
chrX_-_131547596 0.08 ENST00000538204.1
ENST00000370849.3
MBNL3
muscleblind-like splicing regulator 3
chr22_-_24126145 0.08 ENST00000598975.1
AP000349.1
Uncharacterized protein
chr3_-_196911002 0.08 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr9_+_34652164 0.08 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr6_-_119031228 0.08 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chrX_+_56590002 0.08 ENST00000338222.5
UBQLN2
ubiquilin 2
chr12_+_28605426 0.07 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr5_+_43602750 0.07 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr8_-_145754428 0.07 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr3_-_108248169 0.07 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr14_-_53258314 0.07 ENST00000216410.3
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr3_+_195447738 0.07 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr12_-_118796910 0.07 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr12_+_122688090 0.07 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr15_+_75639372 0.07 ENST00000566313.1
ENST00000568059.1
ENST00000568881.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr4_-_74486109 0.07 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr9_-_27005686 0.07 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr12_-_46121554 0.07 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938

Network of associatons between targets according to the STRING database.

First level regulatory network of DBX2_HLX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.4 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.1 0.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.6 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0070409 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.1 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0007498 mesoderm development(GO:0007498)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.5 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.0 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.0 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.0 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.0 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation