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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for DUXA

Z-value: 0.75

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Transcription factors associated with DUXA

Gene Symbol Gene ID Gene Info
DUXA
ENSG00000258873.2 double homeobox A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DUXAhg19_v2_chr19_-_57678811_576788110.118.3e-01Click!

Activity profile of DUXA motif

Sorted Z-values of DUXA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_228678550 1.14 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr1_-_153113927 0.68 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr15_-_80263506 0.66 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr22_-_30642728 0.53 ENST00000403987.3
LIF
leukemia inhibitory factor
chr6_-_133055896 0.48 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr6_-_133055815 0.39 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr22_+_31518938 0.39 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr13_-_30683005 0.38 ENST00000413591.1
ENST00000432770.1
LINC00365
long intergenic non-protein coding RNA 365
chr11_+_93754513 0.36 ENST00000315765.9
HEPHL1
hephaestin-like 1
chr12_-_49259643 0.33 ENST00000309739.5
RND1
Rho family GTPase 1
chr4_-_112993808 0.32 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr1_-_27998689 0.32 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6
interferon, alpha-inducible protein 6
chr12_+_27619743 0.28 ENST00000298876.4
ENST00000416383.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr2_-_175629164 0.27 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr19_-_57967854 0.26 ENST00000321039.3
VN1R1
vomeronasal 1 receptor 1
chr18_+_61554932 0.24 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr12_+_120740119 0.24 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr1_+_44514040 0.24 ENST00000431800.1
ENST00000437643.1
RP5-1198O20.4
RP5-1198O20.4
chr4_-_87770416 0.23 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr1_-_12908578 0.23 ENST00000317869.6
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chr7_+_134331550 0.23 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
BPGM
2,3-bisphosphoglycerate mutase
chr3_-_12587055 0.22 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chrX_+_154444643 0.22 ENST00000286428.5
VBP1
von Hippel-Lindau binding protein 1
chr10_-_112255945 0.22 ENST00000609514.1
ENST00000607952.1
RP11-525A16.4
RP11-525A16.4
chr8_-_29605625 0.21 ENST00000506121.3
LINC00589
long intergenic non-protein coding RNA 589
chr5_-_115872124 0.20 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr17_-_39553844 0.20 ENST00000251645.2
KRT31
keratin 31
chr10_+_118349920 0.20 ENST00000531984.1
PNLIPRP1
pancreatic lipase-related protein 1
chrX_+_64708615 0.20 ENST00000338957.4
ENST00000423889.3
ZC3H12B
zinc finger CCCH-type containing 12B
chr2_+_201994042 0.20 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr9_-_19065082 0.19 ENST00000415524.1
HAUS6
HAUS augmin-like complex, subunit 6
chr12_-_51422017 0.19 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr18_-_59415987 0.18 ENST00000590199.1
ENST00000590968.1
RP11-879F14.1
RP11-879F14.1
chr10_+_69865866 0.18 ENST00000354393.2
MYPN
myopalladin
chr8_-_91095099 0.17 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr1_+_104615595 0.17 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chr18_+_44812072 0.17 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1
CTD-2130O13.1
chr1_+_218683438 0.17 ENST00000443836.1
C1orf143
chromosome 1 open reading frame 143
chr9_-_75695323 0.17 ENST00000419959.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr20_+_58571419 0.16 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26
cadherin 26
chr6_+_89791507 0.16 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr1_+_41447609 0.16 ENST00000543104.1
CTPS1
CTP synthase 1
chrX_+_69501943 0.16 ENST00000509895.1
ENST00000374473.2
ENST00000276066.4
RAB41
RAB41, member RAS oncogene family
chr15_-_65407524 0.15 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr12_-_49581152 0.15 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr7_+_102196256 0.15 ENST00000341656.4
SPDYE2
speedy/RINGO cell cycle regulator family member E2
chr12_-_111395610 0.15 ENST00000548329.1
ENST00000546852.1
RP1-46F2.3
RP1-46F2.3
chrX_-_46759138 0.15 ENST00000377879.3
CXorf31
chromosome X open reading frame 31
chr7_+_102295340 0.15 ENST00000455020.2
SPDYE2B
speedy/RINGO cell cycle regulator family member E2B
chr21_-_19858196 0.14 ENST00000422787.1
TMPRSS15
transmembrane protease, serine 15
chr12_+_25348186 0.14 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5
LYR motif containing 5
chr18_+_68002675 0.14 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr17_-_57158523 0.14 ENST00000581468.1
TRIM37
tripartite motif containing 37
chr6_-_150346607 0.14 ENST00000367341.1
ENST00000286380.2
RAET1L
retinoic acid early transcript 1L
chr6_+_3259148 0.14 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr12_-_75784669 0.14 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2
calcyphosine 2
chr12_-_114211444 0.13 ENST00000510694.2
ENST00000550223.1
RP11-438N16.1
RP11-438N16.1
chr12_+_25348139 0.13 ENST00000557540.2
ENST00000381356.4
LYRM5
LYR motif containing 5
chr2_+_54342533 0.13 ENST00000406041.1
ACYP2
acylphosphatase 2, muscle type
chr3_+_167582561 0.13 ENST00000463642.1
ENST00000464514.1
RP11-298O21.6
RP11-298O21.7
RP11-298O21.6
RP11-298O21.7
chr6_+_3259122 0.13 ENST00000438998.2
ENST00000380305.4
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr12_-_114211474 0.13 ENST00000550905.1
ENST00000547963.1
RP11-438N16.1
RP11-438N16.1
chr16_-_18911366 0.12 ENST00000565224.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr14_+_20937538 0.12 ENST00000361505.5
ENST00000553591.1
PNP
purine nucleoside phosphorylase
chr7_-_34978980 0.12 ENST00000428054.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr11_-_114271139 0.12 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr19_-_47349395 0.12 ENST00000597020.1
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
chrX_-_148571884 0.12 ENST00000537071.1
IDS
iduronate 2-sulfatase
chr1_-_224624730 0.11 ENST00000445239.1
WDR26
WD repeat domain 26
chr17_+_34842473 0.11 ENST00000490126.2
ENST00000225410.4
ZNHIT3
zinc finger, HIT-type containing 3
chrX_+_133733457 0.11 ENST00000440614.1
RP11-308B5.2
RP11-308B5.2
chr19_-_2090131 0.11 ENST00000591326.1
MOB3A
MOB kinase activator 3A
chr12_-_68835991 0.11 ENST00000546086.1
RP11-81H14.2
RP11-81H14.2
chr7_-_93520191 0.11 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr11_+_114270752 0.11 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr7_+_93690435 0.11 ENST00000438538.1
AC003092.1
AC003092.1
chr3_+_118892411 0.11 ENST00000479520.1
ENST00000494855.1
UPK1B
uroplakin 1B
chrX_-_138072729 0.11 ENST00000455663.1
FGF13
fibroblast growth factor 13
chr15_+_66679155 0.11 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr14_+_22600515 0.10 ENST00000390456.3
TRAV8-7
T cell receptor alpha variable 8-7 (non-functional)
chr11_+_5775923 0.10 ENST00000317254.3
OR52N4
olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)
chr16_-_21875424 0.10 ENST00000541674.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr16_-_57836321 0.10 ENST00000569112.1
ENST00000562311.1
ENST00000445690.2
ENST00000379655.4
KIFC3
kinesin family member C3
chr1_+_153003671 0.10 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr1_+_209929494 0.10 ENST00000367026.3
TRAF3IP3
TRAF3 interacting protein 3
chr7_-_93520259 0.10 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr3_+_118892362 0.10 ENST00000497685.1
ENST00000264234.3
UPK1B
uroplakin 1B
chr5_-_115872142 0.10 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr21_-_23058648 0.10 ENST00000416182.1
AF241725.6
AF241725.6
chr6_-_66417107 0.10 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr6_-_10838710 0.10 ENST00000313243.2
MAK
male germ cell-associated kinase
chr2_-_10587897 0.10 ENST00000405333.1
ENST00000443218.1
ODC1
ornithine decarboxylase 1
chr17_-_79849438 0.10 ENST00000331204.4
ENST00000505490.2
ALYREF
Aly/REF export factor
chr5_+_32585605 0.09 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1
SUB1 homolog (S. cerevisiae)
chr3_-_194188956 0.09 ENST00000256031.4
ENST00000446356.1
ATP13A3
ATPase type 13A3
chr17_-_74733404 0.09 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2
serine/arginine-rich splicing factor 2
chr7_+_135611542 0.09 ENST00000416501.1
AC015987.2
AC015987.2
chr5_-_150537279 0.09 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
ANXA6
annexin A6
chr3_-_120461353 0.09 ENST00000483733.1
RABL3
RAB, member of RAS oncogene family-like 3
chr11_-_18610246 0.09 ENST00000379387.4
ENST00000541984.1
UEVLD
UEV and lactate/malate dehyrogenase domains
chr1_+_152975488 0.09 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr11_+_62496114 0.09 ENST00000532583.1
TTC9C
tetratricopeptide repeat domain 9C
chr4_+_147145709 0.09 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr15_-_34447023 0.09 ENST00000560310.1
KATNBL1
katanin p80 subunit B-like 1
chr5_+_172571445 0.09 ENST00000231668.9
ENST00000351486.5
ENST00000352523.6
ENST00000393770.4
BNIP1
BCL2/adenovirus E1B 19kDa interacting protein 1
chr8_-_125577940 0.09 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr1_-_198906528 0.08 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr6_+_12717892 0.08 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr16_+_57220193 0.08 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
RSPRY1
ring finger and SPRY domain containing 1
chr12_-_110434096 0.08 ENST00000320063.9
ENST00000457474.2
ENST00000547815.1
ENST00000361006.5
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr20_+_22034809 0.08 ENST00000449427.1
RP11-125P18.1
RP11-125P18.1
chr10_+_6821545 0.08 ENST00000436383.1
LINC00707
long intergenic non-protein coding RNA 707
chr5_+_154237778 0.08 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr6_+_35996859 0.08 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chr6_-_10838736 0.07 ENST00000536370.1
ENST00000474039.1
MAK
male germ cell-associated kinase
chr11_-_5526834 0.07 ENST00000380237.1
ENST00000396895.1
ENST00000380252.1
HBE1
HBG2
hemoglobin, epsilon 1
hemoglobin, gamma G
chr10_+_134150835 0.07 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr19_+_56187987 0.07 ENST00000411543.2
EPN1
epsin 1
chr4_-_69536346 0.07 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr1_+_50459990 0.07 ENST00000448346.1
AL645730.2
AL645730.2
chr12_-_110434183 0.07 ENST00000360185.4
ENST00000354574.4
ENST00000338373.5
ENST00000343646.5
ENST00000356259.4
ENST00000553118.1
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr4_-_106629796 0.07 ENST00000416543.1
ENST00000515819.1
ENST00000420368.2
ENST00000503746.1
ENST00000340139.5
ENST00000433009.1
INTS12
integrator complex subunit 12
chr2_-_224467002 0.07 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr15_+_78830023 0.07 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr16_+_57220049 0.07 ENST00000562439.1
RSPRY1
ring finger and SPRY domain containing 1
chr6_+_86195088 0.07 ENST00000437581.1
NT5E
5'-nucleotidase, ecto (CD73)
chr3_-_33759699 0.07 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
CLASP2
cytoplasmic linker associated protein 2
chr3_+_45927994 0.07 ENST00000357632.2
ENST00000395963.2
CCR9
chemokine (C-C motif) receptor 9
chr8_-_130587237 0.07 ENST00000520048.1
CCDC26
coiled-coil domain containing 26
chr18_+_61445007 0.07 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr5_-_16742330 0.07 ENST00000505695.1
ENST00000427430.2
MYO10
myosin X
chrX_+_100878079 0.07 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr8_-_86290333 0.07 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1
carbonic anhydrase I
chr11_-_6704513 0.07 ENST00000532203.1
ENST00000288937.6
MRPL17
mitochondrial ribosomal protein L17
chr2_-_175629135 0.07 ENST00000409542.1
ENST00000409219.1
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr2_-_207078086 0.07 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr2_+_201994208 0.07 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_-_232651312 0.07 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr19_+_29456034 0.07 ENST00000589921.1
LINC00906
long intergenic non-protein coding RNA 906
chr9_+_136325149 0.07 ENST00000542192.1
CACFD1
calcium channel flower domain containing 1
chr17_+_61271355 0.06 ENST00000583356.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr8_+_24151553 0.06 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr5_-_89705537 0.06 ENST00000522864.1
ENST00000522083.1
ENST00000522565.1
ENST00000522842.1
ENST00000283122.3
CETN3
centrin, EF-hand protein, 3
chr6_-_73935163 0.06 ENST00000370388.3
KHDC1L
KH homology domain containing 1-like
chrX_+_135614293 0.06 ENST00000370634.3
VGLL1
vestigial like 1 (Drosophila)
chr5_-_152069089 0.06 ENST00000506723.2
AC091969.1
AC091969.1
chr6_+_31126291 0.06 ENST00000376257.3
ENST00000376255.4
TCF19
transcription factor 19
chr18_+_19192228 0.06 ENST00000300413.5
ENST00000579618.1
ENST00000582475.1
SNRPD1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr4_+_79567057 0.06 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr5_+_154238149 0.06 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr12_-_90049828 0.06 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr6_-_71666732 0.06 ENST00000230053.6
B3GAT2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr5_+_67535647 0.06 ENST00000520675.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_-_76817036 0.06 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr21_+_47013566 0.06 ENST00000441095.1
ENST00000424569.1
AL133493.2
AL133493.2
chr8_-_123440779 0.06 ENST00000533992.1
RP11-94A24.1
RP11-94A24.1
chr6_+_53883708 0.06 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP
muscular LMNA-interacting protein
chr5_-_75919253 0.06 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr5_+_125758865 0.06 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr12_-_110434021 0.06 ENST00000355312.3
ENST00000551209.1
ENST00000550186.1
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr7_+_18330035 0.06 ENST00000413509.2
HDAC9
histone deacetylase 9
chr4_-_111563076 0.06 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr6_-_74104856 0.06 ENST00000441145.1
OOEP
oocyte expressed protein
chr17_-_5321549 0.06 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr1_-_154941350 0.06 ENST00000444179.1
ENST00000414115.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr11_-_11374904 0.06 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr2_+_198380763 0.06 ENST00000448447.2
ENST00000409360.1
MOB4
MOB family member 4, phocein
chr12_-_118628315 0.06 ENST00000540561.1
TAOK3
TAO kinase 3
chr12_-_49245936 0.06 ENST00000308025.3
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr5_+_125758813 0.06 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr11_-_123525289 0.06 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr2_-_198062758 0.06 ENST00000328737.2
ANKRD44
ankyrin repeat domain 44
chr4_-_89951028 0.05 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr1_-_21377383 0.05 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr5_-_75919217 0.05 ENST00000504899.1
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr17_+_34842512 0.05 ENST00000588253.1
ENST00000592616.1
ENST00000590858.1
ENST00000588357.1
ZNHIT3
zinc finger, HIT-type containing 3
chr15_-_43398274 0.05 ENST00000382177.2
ENST00000290650.4
UBR1
ubiquitin protein ligase E3 component n-recognin 1
chr1_-_26633480 0.05 ENST00000450041.1
UBXN11
UBX domain protein 11
chr13_+_76362974 0.05 ENST00000497947.2
LMO7
LIM domain 7
chr2_+_86333340 0.05 ENST00000409783.2
ENST00000409277.3
PTCD3
pentatricopeptide repeat domain 3
chr13_-_76111945 0.05 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr19_-_19302931 0.05 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr5_+_154238042 0.05 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
CNOT8
CCR4-NOT transcription complex, subunit 8
chr20_-_44600810 0.05 ENST00000322927.2
ENST00000426788.1
ZNF335
zinc finger protein 335
chr1_+_74701062 0.05 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr12_+_31812121 0.05 ENST00000395763.3
METTL20
methyltransferase like 20
chr17_+_7476136 0.05 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr16_+_67226019 0.05 ENST00000379378.3
E2F4
E2F transcription factor 4, p107/p130-binding
chr15_-_42749711 0.05 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106
zinc finger protein 106
chr8_+_67104323 0.05 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
LINC00967
long intergenic non-protein coding RNA 967
chr5_+_154238096 0.05 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CNOT8
CCR4-NOT transcription complex, subunit 8
chr10_+_78078088 0.05 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr12_-_49245916 0.05 ENST00000552512.1
ENST00000551468.1
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr18_+_61445205 0.05 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_92632542 0.05 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr3_-_58419537 0.04 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
PDHB
pyruvate dehydrogenase (lipoamide) beta
chr8_-_10512569 0.04 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr2_-_55237484 0.04 ENST00000394609.2
RTN4
reticulon 4
chr16_+_21623392 0.04 ENST00000562961.1
METTL9
methyltransferase like 9
chr12_+_28299014 0.04 ENST00000538586.1
ENST00000536154.1
CCDC91
coiled-coil domain containing 91

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.2 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.9 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.3 GO:1904180 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.0 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.0 GO:0006710 androgen catabolic process(GO:0006710)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 0.5 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 0.9 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.7 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters