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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for E2F8

Z-value: 0.62

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Transcription factors associated with E2F8

Gene Symbol Gene ID Gene Info
E2F8
ENSG00000129173.8 E2F transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F8hg19_v2_chr11_-_19263145_19263176-0.049.4e-01Click!

Activity profile of E2F8 motif

Sorted Z-values of E2F8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_136633940 0.43 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr17_-_6915616 0.35 ENST00000575889.1
AC027763.2
Uncharacterized protein
chr8_-_25281747 0.31 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr8_-_120868078 0.28 ENST00000313655.4
DSCC1
DNA replication and sister chromatid cohesion 1
chr19_+_57874835 0.25 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
TRAPPC2P1
ZNF547
AC003002.4
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr2_+_24346324 0.25 ENST00000407625.1
ENST00000420135.2
FAM228B
family with sequence similarity 228, member B
chr4_+_1714548 0.25 ENST00000605571.1
RP11-572O17.1
RP11-572O17.1
chr7_-_21985489 0.25 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L
cell division cycle associated 7-like
chr3_+_122296443 0.22 ENST00000464300.2
PARP15
poly (ADP-ribose) polymerase family, member 15
chr1_+_197871854 0.22 ENST00000436652.1
C1orf53
chromosome 1 open reading frame 53
chr12_-_48499826 0.22 ENST00000551798.1
SENP1
SUMO1/sentrin specific peptidase 1
chr14_-_51135005 0.20 ENST00000556735.1
SAV1
salvador homolog 1 (Drosophila)
chr9_-_8857776 0.18 ENST00000481079.1
PTPRD
protein tyrosine phosphatase, receptor type, D
chr19_+_37464440 0.18 ENST00000455817.1
ENST00000588596.1
ZNF568
zinc finger protein 568
chr19_+_47760777 0.17 ENST00000599398.1
ENST00000595659.1
CCDC9
coiled-coil domain containing 9
chr9_+_8858102 0.17 ENST00000447950.1
ENST00000430766.1
RP11-75C9.1
RP11-75C9.1
chr3_-_123168551 0.17 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr19_+_12203069 0.16 ENST00000430298.2
ENST00000339302.4
ZNF788
ZNF788
zinc finger family member 788
Zinc finger protein 788
chr7_-_56118981 0.16 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
PSPH
phosphoserine phosphatase
chr19_-_51845378 0.16 ENST00000335624.4
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr6_+_26204825 0.15 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr3_+_44754126 0.15 ENST00000449836.1
ENST00000436624.2
ENST00000296091.4
ENST00000411443.1
ZNF502
zinc finger protein 502
chr22_+_19467261 0.15 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45
cell division cycle 45
chr12_+_107168418 0.14 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr15_-_100258029 0.14 ENST00000378904.2
DKFZP779J2370
DKFZP779J2370
chr5_+_172483347 0.14 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chrX_-_53449593 0.14 ENST00000375340.6
ENST00000322213.4
SMC1A
structural maintenance of chromosomes 1A
chr4_-_174255400 0.14 ENST00000506267.1
HMGB2
high mobility group box 2
chr5_-_132166303 0.14 ENST00000440118.1
SHROOM1
shroom family member 1
chr17_-_15165854 0.13 ENST00000395936.1
ENST00000395938.2
PMP22
peripheral myelin protein 22
chr19_+_12203100 0.13 ENST00000596883.1
ZNF788
zinc finger family member 788
chr17_+_38444115 0.13 ENST00000580824.1
ENST00000577249.1
CDC6
cell division cycle 6
chr2_+_63816126 0.13 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr10_-_74385811 0.13 ENST00000603011.1
ENST00000401998.3
ENST00000361114.5
ENST00000604238.1
MICU1
mitochondrial calcium uptake 1
chr7_-_21985656 0.13 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr10_+_35416223 0.13 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr15_-_57025728 0.13 ENST00000559352.1
ZNF280D
zinc finger protein 280D
chr21_+_37477164 0.13 ENST00000422473.1
AP000688.29
AP000688.29
chr11_+_47236489 0.13 ENST00000256996.4
ENST00000378603.3
ENST00000378600.3
ENST00000378601.3
DDB2
damage-specific DNA binding protein 2, 48kDa
chr3_+_14058794 0.13 ENST00000424053.1
ENST00000528067.1
ENST00000429201.1
TPRXL
tetra-peptide repeat homeobox-like
chr6_+_135502501 0.13 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr18_-_47018897 0.12 ENST00000418495.1
RPL17
ribosomal protein L17
chr7_+_128379449 0.12 ENST00000479257.1
CALU
calumenin
chr12_-_8815299 0.12 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr1_+_7844312 0.12 ENST00000377541.1
PER3
period circadian clock 3
chr3_+_14989186 0.12 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr10_-_17659234 0.12 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr9_+_114287433 0.12 ENST00000358151.4
ENST00000355824.3
ENST00000374374.3
ENST00000309235.5
ZNF483
zinc finger protein 483
chr9_-_37904084 0.12 ENST00000377716.2
ENST00000242275.6
SLC25A51
solute carrier family 25, member 51
chr3_+_181429704 0.11 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr1_+_48688357 0.11 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
SLC5A9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr8_+_118532937 0.11 ENST00000297347.3
MED30
mediator complex subunit 30
chr7_-_152373216 0.11 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr10_-_46167722 0.11 ENST00000374366.3
ENST00000344646.5
ZFAND4
zinc finger, AN1-type domain 4
chr2_+_10263298 0.11 ENST00000474701.1
RRM2
ribonucleotide reductase M2
chr7_-_100026280 0.11 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr10_-_74385876 0.11 ENST00000398761.4
MICU1
mitochondrial calcium uptake 1
chr17_-_9479128 0.11 ENST00000574431.1
STX8
syntaxin 8
chr7_+_116593433 0.11 ENST00000323984.3
ENST00000393449.1
ST7
suppression of tumorigenicity 7
chr3_-_107596910 0.11 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
LINC00635
long intergenic non-protein coding RNA 635
chr2_-_113993020 0.11 ENST00000465084.1
PAX8
paired box 8
chr12_-_107168696 0.11 ENST00000551505.1
RP11-144F15.1
Uncharacterized protein
chr11_+_125495862 0.11 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
CHEK1
checkpoint kinase 1
chr6_-_85473156 0.11 ENST00000606784.1
ENST00000606325.1
TBX18
T-box 18
chr20_-_45142154 0.11 ENST00000347606.4
ENST00000457685.2
ZNF334
zinc finger protein 334
chr1_+_33283043 0.10 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP
S100P binding protein
chr12_-_15942309 0.10 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
EPS8
epidermal growth factor receptor pathway substrate 8
chrX_-_135338503 0.10 ENST00000370663.5
MAP7D3
MAP7 domain containing 3
chr17_+_61904766 0.10 ENST00000581842.1
ENST00000582130.1
ENST00000584320.1
ENST00000585123.1
ENST00000580864.1
PSMC5
proteasome (prosome, macropain) 26S subunit, ATPase, 5
chr19_-_58446721 0.10 ENST00000396147.1
ENST00000595569.1
ENST00000599852.1
ENST00000425570.3
ENST00000601593.1
ZNF418
zinc finger protein 418
chr14_-_61190754 0.10 ENST00000216513.4
SIX4
SIX homeobox 4
chr1_-_26232522 0.10 ENST00000399728.1
STMN1
stathmin 1
chr1_-_205719295 0.10 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr15_+_84116106 0.10 ENST00000535412.1
ENST00000324537.5
SH3GL3
SH3-domain GRB2-like 3
chr13_-_41345277 0.10 ENST00000323563.6
MRPS31
mitochondrial ribosomal protein S31
chr18_-_47018869 0.10 ENST00000583036.1
ENST00000580261.1
RPL17
ribosomal protein L17
chr1_-_110052302 0.10 ENST00000369864.4
ENST00000369862.1
AMIGO1
adhesion molecule with Ig-like domain 1
chr4_-_39367949 0.10 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chr4_-_174254823 0.10 ENST00000438704.2
HMGB2
high mobility group box 2
chr7_+_116593292 0.10 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
ST7
suppression of tumorigenicity 7
chr8_+_69242957 0.09 ENST00000518698.1
ENST00000539993.1
C8orf34
chromosome 8 open reading frame 34
chr12_+_111051902 0.09 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1
tectonic family member 1
chr16_-_103572 0.09 ENST00000293860.5
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr22_+_42086547 0.09 ENST00000402966.1
C22orf46
chromosome 22 open reading frame 46
chr16_-_30134441 0.09 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr1_-_27709793 0.09 ENST00000374027.3
ENST00000374025.3
CD164L2
CD164 sialomucin-like 2
chr10_-_17659357 0.09 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr12_+_104682667 0.09 ENST00000527335.1
TXNRD1
thioredoxin reductase 1
chr16_+_58074069 0.09 ENST00000570065.1
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr6_-_28973037 0.09 ENST00000377179.3
ZNF311
zinc finger protein 311
chr6_+_117002339 0.09 ENST00000413340.1
ENST00000368564.1
ENST00000356348.1
KPNA5
karyopherin alpha 5 (importin alpha 6)
chr3_-_125313934 0.09 ENST00000296220.5
OSBPL11
oxysterol binding protein-like 11
chr12_-_123011476 0.09 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2
arginine/serine-rich coiled-coil 2
chr6_+_135502466 0.09 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr16_-_18812746 0.09 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ARL6IP1
RP11-1035H13.3
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr12_-_110939870 0.09 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr16_-_30134266 0.09 ENST00000484663.1
ENST00000478356.1
MAPK3
mitogen-activated protein kinase 3
chr6_+_43603552 0.09 ENST00000372171.4
MAD2L1BP
MAD2L1 binding protein
chr19_+_4402659 0.09 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr2_+_238395879 0.08 ENST00000445024.2
ENST00000338530.4
ENST00000409373.1
MLPH
melanophilin
chr18_+_21719018 0.08 ENST00000585037.1
ENST00000415309.2
ENST00000399481.2
ENST00000577705.1
ENST00000327201.6
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr15_+_84115868 0.08 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr1_+_43637996 0.08 ENST00000528956.1
ENST00000529956.1
WDR65
WD repeat domain 65
chr7_-_56119156 0.08 ENST00000421312.1
ENST00000416592.1
PSPH
phosphoserine phosphatase
chr2_+_238395803 0.08 ENST00000264605.3
MLPH
melanophilin
chr11_-_107729287 0.08 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr16_-_82045049 0.08 ENST00000532128.1
ENST00000328945.5
SDR42E1
short chain dehydrogenase/reductase family 42E, member 1
chr1_-_43638168 0.08 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr6_-_143832793 0.08 ENST00000438118.2
FUCA2
fucosidase, alpha-L- 2, plasma
chr1_+_172745006 0.08 ENST00000432694.2
RP1-15D23.2
RP1-15D23.2
chr18_+_59992527 0.08 ENST00000586569.1
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr6_-_85473073 0.08 ENST00000606621.1
TBX18
T-box 18
chr16_-_67185117 0.08 ENST00000449549.3
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr2_-_86790472 0.08 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr17_-_60005329 0.08 ENST00000251334.6
INTS2
integrator complex subunit 2
chr12_-_48499591 0.08 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr18_+_21718924 0.08 ENST00000399496.3
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr17_+_66243715 0.08 ENST00000359904.3
AMZ2
archaelysin family metallopeptidase 2
chr1_+_224803995 0.08 ENST00000272133.3
CNIH3
cornichon family AMPA receptor auxiliary protein 3
chr2_+_218989991 0.08 ENST00000453237.1
CXCR2
chemokine (C-X-C motif) receptor 2
chr4_+_152330409 0.08 ENST00000513086.1
FAM160A1
family with sequence similarity 160, member A1
chr4_-_129209221 0.08 ENST00000512483.1
PGRMC2
progesterone receptor membrane component 2
chr7_+_116593568 0.08 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr12_-_123011536 0.08 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr4_-_84406218 0.08 ENST00000515303.1
FAM175A
family with sequence similarity 175, member A
chr2_-_70780572 0.07 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr9_+_124088860 0.07 ENST00000373806.1
GSN
gelsolin
chr20_-_524340 0.07 ENST00000400227.3
CSNK2A1
casein kinase 2, alpha 1 polypeptide
chr12_-_8815215 0.07 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chrX_-_7895755 0.07 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
PNPLA4
patatin-like phospholipase domain containing 4
chr3_+_197677047 0.07 ENST00000448864.1
RPL35A
ribosomal protein L35a
chr11_+_9595180 0.07 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr11_-_107729504 0.07 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr5_-_132166579 0.07 ENST00000378679.3
SHROOM1
shroom family member 1
chr15_+_44719394 0.07 ENST00000260327.4
ENST00000396780.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr8_+_71383312 0.07 ENST00000520259.1
RP11-333A23.4
RP11-333A23.4
chr12_-_6772249 0.07 ENST00000467678.1
ENST00000493873.1
ENST00000423703.2
ENST00000412586.2
ENST00000444704.2
ING4
inhibitor of growth family, member 4
chr22_-_30925150 0.07 ENST00000437871.1
SEC14L6
SEC14-like 6 (S. cerevisiae)
chr2_+_10262857 0.07 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr7_+_114562909 0.07 ENST00000423503.1
ENST00000427207.1
MDFIC
MyoD family inhibitor domain containing
chr10_+_35416090 0.07 ENST00000354759.3
CREM
cAMP responsive element modulator
chr8_-_81083618 0.07 ENST00000520795.1
TPD52
tumor protein D52
chr10_+_118083919 0.07 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chr4_+_96012585 0.07 ENST00000502683.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr6_-_30899924 0.07 ENST00000359086.3
SFTA2
surfactant associated 2
chr6_-_90348440 0.07 ENST00000520441.1
ENST00000520318.1
ENST00000523377.1
LYRM2
LYR motif containing 2
chr1_-_43637915 0.07 ENST00000236051.2
EBNA1BP2
EBNA1 binding protein 2
chr12_+_111051832 0.06 ENST00000550703.2
ENST00000551590.1
TCTN1
tectonic family member 1
chr15_-_57025675 0.06 ENST00000558320.1
ZNF280D
zinc finger protein 280D
chr14_-_23624511 0.06 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr10_-_43892279 0.06 ENST00000443950.2
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr12_-_6772303 0.06 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4
inhibitor of growth family, member 4
chr12_+_111843749 0.06 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr22_+_24105394 0.06 ENST00000305199.5
ENST00000382821.3
C22orf15
chromosome 22 open reading frame 15
chr15_-_77712477 0.06 ENST00000560626.2
PEAK1
pseudopodium-enriched atypical kinase 1
chr22_+_20104947 0.06 ENST00000402752.1
RANBP1
RAN binding protein 1
chr1_+_170501270 0.06 ENST00000367763.3
ENST00000367762.1
GORAB
golgin, RAB6-interacting
chr19_+_6740888 0.06 ENST00000596673.1
TRIP10
thyroid hormone receptor interactor 10
chr2_-_24583314 0.06 ENST00000443927.1
ENST00000406921.3
ENST00000412011.1
ITSN2
intersectin 2
chr2_-_37193606 0.06 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr12_+_123011776 0.06 ENST00000450485.2
ENST00000333479.7
KNTC1
kinetochore associated 1
chr1_-_55230165 0.06 ENST00000371279.3
PARS2
prolyl-tRNA synthetase 2, mitochondrial (putative)
chr22_+_20105012 0.06 ENST00000331821.3
ENST00000411892.1
RANBP1
RAN binding protein 1
chr11_+_47586982 0.06 ENST00000426530.2
ENST00000534775.1
PTPMT1
protein tyrosine phosphatase, mitochondrial 1
chr1_-_6295975 0.06 ENST00000343813.5
ENST00000362035.3
ICMT
isoprenylcysteine carboxyl methyltransferase
chr9_-_123639304 0.06 ENST00000436309.1
PHF19
PHD finger protein 19
chr8_+_128426535 0.06 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr21_+_39644305 0.06 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr7_+_128379346 0.06 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chrX_+_131157322 0.06 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chr14_-_61747949 0.06 ENST00000355702.2
TMEM30B
transmembrane protein 30B
chr2_-_230787879 0.06 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr3_-_57113314 0.06 ENST00000338458.4
ENST00000468727.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr3_-_25824925 0.06 ENST00000396649.3
ENST00000428257.1
ENST00000280700.5
NGLY1
N-glycanase 1
chr10_-_12238071 0.06 ENST00000491614.1
ENST00000537776.1
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr8_-_131455835 0.06 ENST00000518721.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr15_+_44719970 0.06 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr11_+_47587129 0.06 ENST00000326656.8
ENST00000326674.9
PTPMT1
protein tyrosine phosphatase, mitochondrial 1
chr17_+_21030260 0.05 ENST00000579303.1
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr2_+_172543967 0.05 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr7_+_114562616 0.05 ENST00000448022.1
MDFIC
MyoD family inhibitor domain containing
chr18_-_47017956 0.05 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr16_+_84875609 0.05 ENST00000563066.1
CRISPLD2
cysteine-rich secretory protein LCCL domain containing 2
chr17_-_29151794 0.05 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr2_+_148778570 0.05 ENST00000407073.1
MBD5
methyl-CpG binding domain protein 5
chr4_+_20255123 0.05 ENST00000504154.1
ENST00000273739.5
SLIT2
slit homolog 2 (Drosophila)
chr11_+_327171 0.05 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr22_+_40742512 0.05 ENST00000454266.2
ENST00000342312.6
ADSL
adenylosuccinate lyase
chr16_-_71264558 0.05 ENST00000448089.2
ENST00000393550.2
ENST00000448691.1
ENST00000393567.2
ENST00000321489.5
ENST00000539973.1
ENST00000288168.10
ENST00000545267.1
ENST00000541601.1
ENST00000538248.1
HYDIN
HYDIN, axonemal central pair apparatus protein
chr3_-_185542761 0.05 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr2_-_63815860 0.05 ENST00000272321.7
ENST00000431065.1
WDPCP
WD repeat containing planar cell polarity effector
chr1_+_25599018 0.05 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD
Rh blood group, D antigen
chr11_-_13484713 0.05 ENST00000526841.1
ENST00000529708.1
ENST00000278174.5
ENST00000528120.1
BTBD10
BTB (POZ) domain containing 10
chr11_+_17298297 0.05 ENST00000529010.1
NUCB2
nucleobindin 2
chr14_-_100841670 0.05 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS
tryptophanyl-tRNA synthetase
chr1_-_20834586 0.05 ENST00000264198.3
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr1_+_201798269 0.05 ENST00000361565.4
IPO9
importin 9
chr6_+_127588020 0.05 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146
ring finger protein 146
chr6_+_10585979 0.05 ENST00000265012.4
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr10_-_12237820 0.05 ENST00000378937.3
ENST00000378927.3
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990637 response to prolactin(GO:1990637)
0.1 0.2 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.2 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:1900214 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0071810 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0071623 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.0 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.0 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.0 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.0 GO:0031436 BRCA1-BARD1 complex(GO:0031436)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0004918 interleukin-8 receptor activity(GO:0004918)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation