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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for E4F1

Z-value: 0.50

Motif logo

Transcription factors associated with E4F1

Gene Symbol Gene ID Gene Info
ENSG00000167967.11 E4F transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E4F1hg19_v2_chr16_+_2273558_2273637-0.621.9e-01Click!

Activity profile of E4F1 motif

Sorted Z-values of E4F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_32812420 0.23 ENST00000374881.2
proteasome (prosome, macropain) subunit, beta type, 8
chr19_+_45504688 0.22 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr20_+_33146510 0.20 ENST00000397709.1
microtubule-associated protein 1 light chain 3 alpha
chr6_+_32812568 0.18 ENST00000414474.1
proteasome (prosome, macropain) subunit, beta type, 9
chr16_+_68057179 0.17 ENST00000567100.1
ENST00000432752.1
ENST00000569289.1
ENST00000564781.1
dihydrouridine synthase 2
chr6_+_30029008 0.17 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
zinc ribbon domain containing 1
chr14_-_23388338 0.17 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
RNA binding motif protein 23
chr6_+_26204825 0.16 ENST00000360441.4
histone cluster 1, H4e
chr22_+_39101728 0.14 ENST00000216044.5
ENST00000484657.1
GTP binding protein 1
chr9_-_99381660 0.13 ENST00000375240.3
ENST00000463569.1
cell division cycle 14B
chr14_+_94492674 0.13 ENST00000203664.5
ENST00000553723.1
OTU domain, ubiquitin aldehyde binding 2
chr1_+_212208919 0.13 ENST00000366991.4
ENST00000542077.1
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr16_+_68057153 0.13 ENST00000358896.6
ENST00000568099.2
dihydrouridine synthase 2
chr20_+_34203794 0.12 ENST00000374273.3
sperm associated antigen 4
chr1_-_151254362 0.12 ENST00000447795.2
Uncharacterized protein
chr20_+_33292068 0.12 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
tumor protein p53 inducible nuclear protein 2
chr8_-_29208183 0.11 ENST00000240100.2
dual specificity phosphatase 4
chr2_-_216300784 0.11 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr9_-_99382065 0.11 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
cell division cycle 14B
chr1_-_8086343 0.11 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERBB receptor feedback inhibitor 1
chr17_+_7476136 0.11 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr19_-_10024496 0.11 ENST00000593091.1
olfactomedin 2
chr12_-_107168696 0.11 ENST00000551505.1
Uncharacterized protein
chr17_-_4643114 0.10 ENST00000293778.6
chemokine (C-X-C motif) ligand 16
chr1_+_70820451 0.10 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HERV-H LTR-associating 3
chr12_-_93835665 0.10 ENST00000552442.1
ENST00000550657.1
ubiquitin-conjugating enzyme E2N
chr12_-_51566592 0.10 ENST00000257915.5
ENST00000548115.1
transcription factor CP2
chr22_-_38902300 0.10 ENST00000403230.1
DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr7_+_30174574 0.10 ENST00000409688.1
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr17_-_685559 0.10 ENST00000301329.6
glyoxalase domain containing 4
chr22_+_32340481 0.10 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr22_+_32340447 0.09 ENST00000248975.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr6_-_34664612 0.09 ENST00000374023.3
ENST00000374026.3
chromosome 6 open reading frame 106
chr12_-_51566562 0.09 ENST00000548108.1
transcription factor CP2
chr2_-_62115659 0.09 ENST00000544185.1
chaperonin containing TCP1, subunit 4 (delta)
chr12_+_107168418 0.09 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8 guanine nucleotide exchange factor B
chr12_+_122150646 0.09 ENST00000449592.2
transmembrane protein 120B
chr16_-_3767506 0.09 ENST00000538171.1
TNF receptor-associated protein 1
chr17_-_7165662 0.09 ENST00000571881.2
ENST00000360325.7
claudin 7
chr15_-_41047421 0.09 ENST00000560460.1
ENST00000338376.3
ENST00000560905.1
regulator of microtubule dynamics 3
chr11_+_111411384 0.09 ENST00000375615.3
ENST00000525126.1
ENST00000436913.2
ENST00000533265.1
layilin
chr9_+_125027127 0.09 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
mitochondrial ribosome recycling factor
chr17_+_53342311 0.08 ENST00000226067.5
hepatic leukemia factor
chr16_-_3767551 0.08 ENST00000246957.5
TNF receptor-associated protein 1
chr19_+_52693259 0.07 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
protein phosphatase 2, regulatory subunit A, alpha
chr12_-_51566849 0.07 ENST00000549867.1
ENST00000307660.4
transcription factor CP2
chr10_+_119000604 0.07 ENST00000298472.5
solute carrier family 18 (vesicular monoamine transporter), member 2
chr3_+_38206975 0.07 ENST00000446845.1
ENST00000311806.3
oxidative stress responsive 1
chr1_-_16482554 0.07 ENST00000358432.5
EPH receptor A2
chr5_-_138211051 0.07 ENST00000518785.1
leucine rich repeat transmembrane neuronal 2
chr22_-_41252962 0.07 ENST00000216218.3
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr17_-_80231557 0.07 ENST00000392334.2
ENST00000314028.6
casein kinase 1, delta
chr8_-_66754172 0.07 ENST00000401827.3
phosphodiesterase 7A
chr8_+_94929168 0.07 ENST00000518107.1
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr16_+_29911864 0.07 ENST00000308748.5
aspartate beta-hydroxylase domain containing 1
chr17_-_685493 0.07 ENST00000536578.1
ENST00000301328.5
ENST00000576419.1
glyoxalase domain containing 4
chr17_-_4643161 0.07 ENST00000574412.1
chemokine (C-X-C motif) ligand 16
chr6_-_163148700 0.06 ENST00000366894.1
ENST00000338468.3
parkin RBR E3 ubiquitin protein ligase
chr2_+_220408724 0.06 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
transmembrane protein 198
chr17_+_18087553 0.06 ENST00000399138.4
alkB, alkylation repair homolog 5 (E. coli)
chr2_-_62115725 0.06 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
chaperonin containing TCP1, subunit 4 (delta)
chr5_+_122424816 0.06 ENST00000407847.4
PR domain containing 6
chr16_+_68056844 0.06 ENST00000565263.1
dihydrouridine synthase 2
chr9_+_125026882 0.06 ENST00000297908.3
ENST00000373730.3
ENST00000546115.1
ENST00000344641.3
mitochondrial ribosome recycling factor
chr4_+_1873100 0.06 ENST00000508803.1
Wolf-Hirschhorn syndrome candidate 1
chr21_-_40720995 0.05 ENST00000380749.5
high mobility group nucleosome binding domain 1
chr6_+_44355257 0.05 ENST00000371477.3
cell division cycle 5-like
chr8_+_94929077 0.05 ENST00000297598.4
ENST00000520614.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr6_-_163148780 0.05 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
parkin RBR E3 ubiquitin protein ligase
chr5_-_138210977 0.05 ENST00000274711.6
ENST00000521094.2
leucine rich repeat transmembrane neuronal 2
chrX_+_153672468 0.05 ENST00000393600.3
family with sequence similarity 50, member A
chr5_-_132948216 0.05 ENST00000265342.7
follistatin-like 4
chr3_+_185304059 0.05 ENST00000427465.2
SUMO1/sentrin/SMT3 specific peptidase 2
chrX_-_13835398 0.05 ENST00000475307.1
glycoprotein M6B
chr16_+_27561449 0.05 ENST00000261588.4
KIAA0556
chr19_-_59066452 0.04 ENST00000312547.2
charged multivesicular body protein 2A
chr4_+_75311019 0.04 ENST00000502307.1
amphiregulin
chr2_+_202899310 0.04 ENST00000286201.1
frizzled family receptor 7
chr3_-_107941230 0.04 ENST00000264538.3
intraflagellar transport 57 homolog (Chlamydomonas)
chr4_-_186456652 0.04 ENST00000284767.5
ENST00000284770.5
PDZ and LIM domain 3
chr21_-_40720974 0.04 ENST00000380748.1
high mobility group nucleosome binding domain 1
chr3_+_185303962 0.04 ENST00000296257.5
SUMO1/sentrin/SMT3 specific peptidase 2
chr6_-_53213780 0.04 ENST00000304434.6
ENST00000370918.4
ELOVL fatty acid elongase 5
chr12_+_111471828 0.04 ENST00000261726.6
cut-like homeobox 2
chr11_+_111410998 0.04 ENST00000533999.1
layilin
chr1_-_150602035 0.04 ENST00000503241.1
ENST00000369016.4
ENST00000339643.5
ENST00000271690.8
ENST00000356527.5
ENST00000362052.7
ENST00000503345.1
ENST00000369014.5
ENST00000369009.3
endosulfine alpha
chr2_-_75426826 0.04 ENST00000305249.5
tachykinin receptor 1
chr11_+_66188475 0.04 ENST00000311034.2
neuronal PAS domain protein 4
chr4_-_186456766 0.04 ENST00000284771.6
PDZ and LIM domain 3
chr5_-_133706695 0.04 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr7_+_30174426 0.04 ENST00000324453.8
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr15_-_53082178 0.04 ENST00000305901.5
one cut homeobox 1
chr11_-_33183048 0.04 ENST00000438862.2
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr6_+_127588020 0.04 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
ring finger protein 146
chr7_+_30174668 0.04 ENST00000415604.1
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr17_-_40540377 0.03 ENST00000404395.3
ENST00000389272.3
ENST00000585517.1
ENST00000588065.1
signal transducer and activator of transcription 3 (acute-phase response factor)
chr1_+_2005126 0.03 ENST00000495347.1
protein kinase C, zeta
chr6_+_163148973 0.03 ENST00000366888.2
PARK2 co-regulated
chrX_+_152224766 0.03 ENST00000370265.4
ENST00000447306.1
paraneoplastic Ma antigen 3
chr12_+_122516626 0.03 ENST00000319080.7
MLX interacting protein
chr2_+_75185619 0.03 ENST00000483063.1
polymerase (DNA-directed), epsilon 4, accessory subunit
chr17_+_61851157 0.03 ENST00000578681.1
ENST00000583590.1
DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr17_-_36831156 0.03 ENST00000325814.5
chromosome 17 open reading frame 96
chr17_+_4643337 0.03 ENST00000592813.1
zinc finger, MYND-type containing 15
chr17_+_685513 0.03 ENST00000304478.4
RNA methyltransferase like 1
chr17_+_39845134 0.03 ENST00000591776.1
ENST00000469257.1
eukaryotic translation initiation factor 1
chr1_+_39456895 0.03 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
akirin 1
chr6_-_31774714 0.03 ENST00000375661.5
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_-_70820357 0.03 ENST00000370944.4
ENST00000262346.6
ankyrin repeat domain 13C
chr17_-_40540484 0.03 ENST00000588969.1
signal transducer and activator of transcription 3 (acute-phase response factor)
chr1_-_32110467 0.03 ENST00000440872.2
ENST00000373703.4
penta-EF-hand domain containing 1
chr11_-_6633799 0.03 ENST00000299424.4
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr16_-_46782221 0.02 ENST00000394809.4
myosin light chain kinase 3
chr6_+_15249128 0.02 ENST00000397311.3
jumonji, AT rich interactive domain 2
chr17_+_4643300 0.02 ENST00000433935.1
zinc finger, MYND-type containing 15
chr22_+_18121356 0.02 ENST00000317582.5
ENST00000543133.1
ENST00000538149.1
ENST00000337612.5
ENST00000493680.1
BCL2-like 13 (apoptosis facilitator)
chr20_-_44600810 0.02 ENST00000322927.2
ENST00000426788.1
zinc finger protein 335
chr11_-_67276100 0.02 ENST00000301488.3
cyclin-dependent kinase 2 associated protein 2
chr16_+_29973351 0.02 ENST00000602948.1
ENST00000279396.6
ENST00000575829.2
ENST00000561899.2
transmembrane protein 219
chr11_-_3818688 0.02 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
nucleoporin 98kDa
chr20_+_44420617 0.02 ENST00000449078.1
ENST00000456939.1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr20_+_33292507 0.02 ENST00000414082.1
tumor protein p53 inducible nuclear protein 2
chr20_+_44420570 0.02 ENST00000372622.3
deoxynucleotidyltransferase, terminal, interacting protein 1
chr1_+_2005425 0.02 ENST00000461106.2
protein kinase C, zeta
chr9_-_131644306 0.02 ENST00000302586.3
cysteine conjugate-beta lyase, cytoplasmic
chr6_-_47445214 0.02 ENST00000604014.1
RP11-385F7.1
chr5_-_95297678 0.02 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chr3_+_139654018 0.01 ENST00000458420.3
calsyntenin 2
chr12_+_107168342 0.01 ENST00000392837.4
RIC8 guanine nucleotide exchange factor B
chr17_+_71161140 0.01 ENST00000357585.2
somatostatin receptor 2
chr11_-_3818932 0.01 ENST00000324932.7
ENST00000359171.4
nucleoporin 98kDa
chr11_-_8680383 0.01 ENST00000299550.6
tripartite motif containing 66
chr6_+_28048753 0.01 ENST00000377325.1
zinc finger protein 165
chr12_-_110011288 0.01 ENST00000540016.1
ENST00000266839.5
methylmalonic aciduria (cobalamin deficiency) cblB type
chr20_-_62258394 0.01 ENST00000370077.1
glucocorticoid modulatory element binding protein 2
chr3_-_185655795 0.01 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
transformer 2 beta homolog (Drosophila)
chr11_+_3819049 0.01 ENST00000396986.2
ENST00000300730.6
ENST00000532535.1
ENST00000396993.4
ENST00000396991.2
ENST00000532523.1
ENST00000459679.1
ENST00000464261.1
ENST00000464906.2
ENST00000464441.1
post-GPI attachment to proteins 2
chr17_+_41476327 0.01 ENST00000320033.4
ADP-ribosylation factor-like 4D
chr7_-_129592471 0.01 ENST00000473814.2
ENST00000490974.1
ubiquitin-conjugating enzyme E2H
chr8_-_94928861 0.01 ENST00000607097.1
microRNA 378d-2
chr7_-_140624499 0.01 ENST00000288602.6
v-raf murine sarcoma viral oncogene homolog B
chr3_-_107941209 0.01 ENST00000492106.1
intraflagellar transport 57 homolog (Chlamydomonas)
chr2_-_240964716 0.01 ENST00000404554.1
ENST00000407129.3
ENST00000307300.4
ENST00000443626.1
ENST00000252711.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr6_-_29595779 0.01 ENST00000355973.3
ENST00000377012.4
gamma-aminobutyric acid (GABA) B receptor, 1
chr2_-_157189180 0.01 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
nuclear receptor subfamily 4, group A, member 2
chr19_+_13858593 0.01 ENST00000221554.8
coiled-coil domain containing 130
chr11_+_66059339 0.01 ENST00000327259.4
transmembrane protein 151A
chr17_+_35294075 0.01 ENST00000254457.5
LIM homeobox 1
chr17_-_40540586 0.01 ENST00000264657.5
signal transducer and activator of transcription 3 (acute-phase response factor)
chr19_+_45349432 0.00 ENST00000252485.4
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr19_-_59066327 0.00 ENST00000596708.1
ENST00000601220.1
ENST00000597848.1
charged multivesicular body protein 2A
chr12_-_93836028 0.00 ENST00000318066.2
ubiquitin-conjugating enzyme E2N
chr8_+_94929273 0.00 ENST00000518573.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_-_80231300 0.00 ENST00000398519.5
ENST00000580446.1
casein kinase 1, delta
chr16_-_27561209 0.00 ENST00000356183.4
ENST00000561623.1
general transcription factor IIIC, polypeptide 1, alpha 220kDa
chr4_+_75310851 0.00 ENST00000395748.3
ENST00000264487.2
amphiregulin

Network of associatons between targets according to the STRING database.

First level regulatory network of E4F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.4 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.1 GO:0014028 notochord formation(GO:0014028) axial mesoderm formation(GO:0048320)
0.0 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.0 GO:0035106 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051) operant conditioning(GO:0035106)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.0 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)