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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EGR1_EGR4

Z-value: 0.77

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Transcription factors associated with EGR1_EGR4

Gene Symbol Gene ID Gene Info
EGR1
ENSG00000120738.7 early growth response 1
EGR4
ENSG00000135625.6 early growth response 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR1hg19_v2_chr5_+_137801160_137801179-0.542.7e-01Click!

Activity profile of EGR1_EGR4 motif

Sorted Z-values of EGR1_EGR4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_96928516 1.08 ENST00000602703.1
RP11-2B6.3
RP11-2B6.3
chr21_+_37529055 0.84 ENST00000270190.4
DOPEY2
dopey family member 2
chr19_+_589893 0.53 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr7_-_44365020 0.46 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr1_+_35734616 0.44 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr15_-_80263506 0.41 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr12_+_105724613 0.39 ENST00000549934.2
C12orf75
chromosome 12 open reading frame 75
chr2_+_86116396 0.35 ENST00000455121.3
AC105053.4
AC105053.4
chrX_-_154033793 0.32 ENST00000369534.3
ENST00000413259.3
MPP1
membrane protein, palmitoylated 1, 55kDa
chr11_+_35965531 0.31 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
LDLRAD3
low density lipoprotein receptor class A domain containing 3
chr6_-_4135825 0.30 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
ECI2
enoyl-CoA delta isomerase 2
chrX_-_154033686 0.28 ENST00000453245.1
ENST00000428488.1
ENST00000369531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr2_+_191513959 0.27 ENST00000337386.5
ENST00000357215.5
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr6_-_110500826 0.27 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr17_+_47439733 0.26 ENST00000507337.1
RP11-1079K10.3
RP11-1079K10.3
chr12_+_105724414 0.26 ENST00000443585.1
ENST00000552457.1
ENST00000549893.1
C12orf75
chromosome 12 open reading frame 75
chr12_+_130822606 0.26 ENST00000546060.1
ENST00000539400.1
PIWIL1
piwi-like RNA-mediated gene silencing 1
chr19_-_39360561 0.24 ENST00000593809.1
ENST00000593424.1
RINL
Ras and Rab interactor-like
chr7_-_32931623 0.24 ENST00000452926.1
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr6_+_12012170 0.24 ENST00000487103.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr2_-_128145498 0.23 ENST00000409179.2
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr17_-_56065540 0.23 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr7_-_127032363 0.22 ENST00000393312.1
ZNF800
zinc finger protein 800
chr19_+_37096194 0.21 ENST00000460670.1
ENST00000292928.2
ENST00000439428.1
ZNF382
zinc finger protein 382
chr1_-_38273840 0.21 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr2_+_99758161 0.21 ENST00000409684.1
C2ORF15
Uncharacterized protein C2orf15
chr14_+_100070869 0.21 ENST00000502101.2
RP11-543C4.1
RP11-543C4.1
chr15_-_71146347 0.21 ENST00000559140.2
LARP6
La ribonucleoprotein domain family, member 6
chr13_-_37494391 0.21 ENST00000379826.4
SMAD9
SMAD family member 9
chr5_-_142784003 0.20 ENST00000416954.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr8_+_26149274 0.20 ENST00000522535.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr2_-_202316169 0.19 ENST00000430254.1
TRAK2
trafficking protein, kinesin binding 2
chr8_-_63951730 0.19 ENST00000260118.6
GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr7_-_100493744 0.19 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chrX_-_108976410 0.19 ENST00000504980.1
ACSL4
acyl-CoA synthetase long-chain family member 4
chr17_+_44668387 0.19 ENST00000576040.1
NSF
N-ethylmaleimide-sensitive factor
chr22_+_38597889 0.19 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr5_+_63461642 0.18 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
RNF180
ring finger protein 180
chrX_-_108976521 0.18 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4
acyl-CoA synthetase long-chain family member 4
chr6_-_4135693 0.18 ENST00000495548.1
ENST00000380125.2
ENST00000465828.1
ECI2
enoyl-CoA delta isomerase 2
chr9_+_129986734 0.18 ENST00000444677.1
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr2_+_191513789 0.18 ENST00000409581.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr16_+_23847339 0.18 ENST00000303531.7
PRKCB
protein kinase C, beta
chr1_+_65886262 0.18 ENST00000371065.4
LEPROT
leptin receptor overlapping transcript
chr12_+_107349606 0.17 ENST00000547242.1
ENST00000551489.1
ENST00000550344.1
C12orf23
chromosome 12 open reading frame 23
chr5_-_145214848 0.17 ENST00000505416.1
ENST00000334744.4
ENST00000358004.2
ENST00000511435.1
PRELID2
PRELI domain containing 2
chr8_-_102217515 0.17 ENST00000520347.1
ENST00000523922.1
ENST00000520984.1
ZNF706
zinc finger protein 706
chr21_-_44527613 0.17 ENST00000380276.2
ENST00000398137.1
ENST00000291552.4
U2AF1
U2 small nuclear RNA auxiliary factor 1
chr1_+_212458834 0.17 ENST00000261461.2
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr10_-_75255724 0.17 ENST00000342558.3
ENST00000360663.5
ENST00000394829.2
ENST00000394828.2
ENST00000394822.2
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr15_+_52311398 0.17 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr21_+_17102311 0.16 ENST00000285679.6
ENST00000351097.5
ENST00000285681.2
ENST00000400183.2
USP25
ubiquitin specific peptidase 25
chr12_-_64616019 0.16 ENST00000311915.8
ENST00000398055.3
ENST00000544871.1
C12orf66
chromosome 12 open reading frame 66
chr5_-_145214893 0.16 ENST00000394450.2
PRELID2
PRELI domain containing 2
chr1_+_6845578 0.16 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr19_-_49622348 0.16 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr16_-_31021717 0.16 ENST00000565419.1
STX1B
syntaxin 1B
chr9_+_91003271 0.16 ENST00000375859.3
ENST00000541629.1
SPIN1
spindlin 1
chr12_-_109125285 0.15 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr1_+_65886326 0.15 ENST00000371059.3
ENST00000371060.3
ENST00000349533.6
ENST00000406510.3
LEPR
leptin receptor
chr16_+_23847267 0.15 ENST00000321728.7
PRKCB
protein kinase C, beta
chr3_+_37903432 0.15 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chrX_+_107068959 0.15 ENST00000451923.1
MID2
midline 2
chr15_+_84116106 0.15 ENST00000535412.1
ENST00000324537.5
SH3GL3
SH3-domain GRB2-like 3
chr19_-_38714847 0.15 ENST00000420980.2
ENST00000355526.4
DPF1
D4, zinc and double PHD fingers family 1
chr1_+_6052700 0.15 ENST00000378092.1
ENST00000445501.1
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr19_-_51568324 0.15 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
KLK13
kallikrein-related peptidase 13
chr9_+_19230433 0.14 ENST00000434457.2
ENST00000602925.1
DENND4C
DENN/MADD domain containing 4C
chr22_-_29137771 0.14 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr13_+_76123883 0.14 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr16_+_29817841 0.14 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_+_46185111 0.14 ENST00000582104.1
ENST00000584335.1
SNX11
sorting nexin 11
chr13_-_37494365 0.14 ENST00000350148.5
SMAD9
SMAD family member 9
chr1_+_6845497 0.14 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr18_-_51750948 0.14 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr9_+_114659046 0.14 ENST00000374279.3
UGCG
UDP-glucose ceramide glucosyltransferase
chr1_-_85156417 0.14 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr18_+_12948000 0.14 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1L
SEH1-like (S. cerevisiae)
chr17_-_15466850 0.14 ENST00000438826.3
ENST00000225576.3
ENST00000519970.1
ENST00000518321.1
ENST00000428082.2
ENST00000522212.2
TVP23C
TVP23C-CDRT4
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TVP23C-CDRT4 readthrough
chr7_+_33169142 0.14 ENST00000242067.6
ENST00000350941.3
ENST00000396127.2
ENST00000355070.2
ENST00000354265.4
ENST00000425508.2
BBS9
Bardet-Biedl syndrome 9
chr14_-_51027838 0.14 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr14_-_53619816 0.14 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1
DDHD domain containing 1
chr6_+_138188378 0.13 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr9_-_13279589 0.13 ENST00000319217.7
MPDZ
multiple PDZ domain protein
chr4_+_26859300 0.13 ENST00000494628.2
STIM2
stromal interaction molecule 2
chr7_-_35840198 0.13 ENST00000412856.1
ENST00000437235.3
ENST00000424194.1
AC007551.3
AC007551.3
chr6_+_43739697 0.13 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr22_+_29469100 0.13 ENST00000327813.5
ENST00000407188.1
KREMEN1
kringle containing transmembrane protein 1
chr2_+_191513587 0.13 ENST00000416973.1
ENST00000426601.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr3_-_185542761 0.13 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_-_93426998 0.13 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr13_+_41635617 0.13 ENST00000542082.1
WBP4
WW domain binding protein 4
chr11_-_46142948 0.13 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr4_-_819901 0.13 ENST00000304062.6
CPLX1
complexin 1
chr16_+_2588012 0.13 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr17_-_4269768 0.13 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr2_+_191745560 0.13 ENST00000338435.4
GLS
glutaminase
chr18_-_5295679 0.12 ENST00000582388.1
ZBTB14
zinc finger and BTB domain containing 14
chr9_+_131451480 0.12 ENST00000322030.8
SET
SET nuclear oncogene
chrX_-_107334790 0.12 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr5_-_137878887 0.12 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr1_+_65886244 0.12 ENST00000344610.8
LEPR
leptin receptor
chr19_+_52800410 0.12 ENST00000595962.1
ENST00000598016.1
ENST00000334564.7
ENST00000490272.1
ZNF480
zinc finger protein 480
chr3_+_196366616 0.12 ENST00000426755.1
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr20_+_31350184 0.12 ENST00000328111.2
ENST00000353855.2
ENST00000348286.2
DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr11_+_95523823 0.12 ENST00000538658.1
CEP57
centrosomal protein 57kDa
chrX_+_21959108 0.12 ENST00000457085.1
SMS
spermine synthase
chr9_-_86432547 0.12 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr4_-_185395191 0.12 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr18_+_22006646 0.12 ENST00000585067.1
ENST00000578221.1
IMPACT
impact RWD domain protein
chr7_+_43803790 0.12 ENST00000424330.1
BLVRA
biliverdin reductase A
chr7_+_100797726 0.12 ENST00000429457.1
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr12_-_96794330 0.12 ENST00000261211.3
CDK17
cyclin-dependent kinase 17
chr12_+_12510045 0.12 ENST00000314565.4
LOH12CR1
loss of heterozygosity, 12, chromosomal region 1
chr14_-_45603657 0.12 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr13_-_52026730 0.12 ENST00000420668.2
INTS6
integrator complex subunit 6
chr5_+_172483347 0.12 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr21_+_38445539 0.12 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr12_+_95867919 0.12 ENST00000261220.9
ENST00000549502.1
ENST00000553151.1
ENST00000550777.1
ENST00000551840.1
METAP2
methionyl aminopeptidase 2
chr17_+_55334364 0.12 ENST00000322684.3
ENST00000579590.1
MSI2
musashi RNA-binding protein 2
chr1_+_150898733 0.12 ENST00000525956.1
SETDB1
SET domain, bifurcated 1
chr9_+_129987488 0.11 ENST00000446764.1
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr12_-_118498911 0.11 ENST00000544233.1
WSB2
WD repeat and SOCS box containing 2
chr22_-_39548511 0.11 ENST00000434260.1
CBX7
chromobox homolog 7
chr2_-_27341765 0.11 ENST00000405600.1
CGREF1
cell growth regulator with EF-hand domain 1
chr6_+_111195973 0.11 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr14_-_102553371 0.11 ENST00000553585.1
ENST00000216281.8
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr1_+_201924619 0.11 ENST00000367287.4
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr3_+_3168600 0.11 ENST00000251607.6
ENST00000339437.6
ENST00000280591.6
ENST00000420393.1
TRNT1
tRNA nucleotidyl transferase, CCA-adding, 1
chr15_+_86087267 0.11 ENST00000558166.1
AKAP13
A kinase (PRKA) anchor protein 13
chr5_+_179921344 0.11 ENST00000261951.4
CNOT6
CCR4-NOT transcription complex, subunit 6
chr16_+_21610879 0.11 ENST00000396014.4
METTL9
methyltransferase like 9
chr18_-_658244 0.11 ENST00000585033.1
ENST00000323813.3
C18orf56
chromosome 18 open reading frame 56
chr2_+_153191706 0.11 ENST00000288670.9
FMNL2
formin-like 2
chr11_-_123525289 0.11 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr16_+_1203194 0.11 ENST00000348261.5
ENST00000358590.4
CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr1_-_23694794 0.11 ENST00000374608.3
ZNF436
zinc finger protein 436
chr6_+_12012536 0.11 ENST00000379388.2
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr1_-_38471156 0.11 ENST00000373016.3
FHL3
four and a half LIM domains 3
chr3_-_32612263 0.11 ENST00000432458.2
ENST00000424991.1
ENST00000273130.4
DYNC1LI1
dynein, cytoplasmic 1, light intermediate chain 1
chr3_+_134514093 0.11 ENST00000398015.3
EPHB1
EPH receptor B1
chr16_-_54962415 0.11 ENST00000501177.3
ENST00000559598.2
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chrX_-_101410762 0.11 ENST00000543160.1
ENST00000333643.3
BEX5
brain expressed, X-linked 5
chr4_-_36246060 0.11 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_+_48112371 0.11 ENST00000594866.1
GLTSCR1
glioma tumor suppressor candidate region gene 1
chr14_-_21945057 0.11 ENST00000397762.1
RAB2B
RAB2B, member RAS oncogene family
chr17_-_15466742 0.11 ENST00000584811.1
ENST00000419890.2
TVP23C
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
chr3_-_135915401 0.11 ENST00000491050.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr14_-_69658127 0.11 ENST00000556182.1
RP11-363J20.1
RP11-363J20.1
chr21_+_44394742 0.11 ENST00000432907.2
PKNOX1
PBX/knotted 1 homeobox 1
chr11_+_102980126 0.11 ENST00000375735.2
DYNC2H1
dynein, cytoplasmic 2, heavy chain 1
chr1_-_197744763 0.11 ENST00000422998.1
DENND1B
DENN/MADD domain containing 1B
chrX_-_154033661 0.11 ENST00000393531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr3_+_11196206 0.11 ENST00000431010.2
HRH1
histamine receptor H1
chr2_-_98612379 0.10 ENST00000425805.2
TMEM131
transmembrane protein 131
chr6_+_12008986 0.10 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr1_+_35734562 0.10 ENST00000314607.6
ENST00000373297.2
ZMYM4
zinc finger, MYM-type 4
chrX_+_135579238 0.10 ENST00000535601.1
ENST00000448450.1
ENST00000425695.1
HTATSF1
HIV-1 Tat specific factor 1
chr3_-_185542817 0.10 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr14_+_23352374 0.10 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr5_+_179921430 0.10 ENST00000393356.1
CNOT6
CCR4-NOT transcription complex, subunit 6
chr2_+_30370382 0.10 ENST00000402708.1
YPEL5
yippee-like 5 (Drosophila)
chr3_+_75721428 0.10 ENST00000463183.1
LINC00960
long intergenic non-protein coding RNA 960
chr17_+_36508826 0.10 ENST00000580660.1
SOCS7
suppressor of cytokine signaling 7
chr5_-_54523143 0.10 ENST00000513312.1
MCIDAS
multiciliate differentiation and DNA synthesis associated cell cycle protein
chr10_+_98592009 0.10 ENST00000540664.1
ENST00000371103.3
LCOR
ligand dependent nuclear receptor corepressor
chr2_+_64068074 0.10 ENST00000394417.2
ENST00000484142.1
ENST00000482668.1
ENST00000467648.2
UGP2
UDP-glucose pyrophosphorylase 2
chr2_-_38829768 0.10 ENST00000378915.3
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr1_-_204119009 0.10 ENST00000444817.1
ETNK2
ethanolamine kinase 2
chr10_-_95462265 0.10 ENST00000536233.1
ENST00000359204.4
ENST00000371430.2
ENST00000394100.2
FRA10AC1
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
chr1_+_235490659 0.10 ENST00000488594.1
GGPS1
geranylgeranyl diphosphate synthase 1
chr12_-_112856623 0.10 ENST00000551291.2
RPL6
ribosomal protein L6
chr9_-_13279563 0.10 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr2_-_148778323 0.10 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr22_-_24181174 0.10 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr2_+_191208601 0.10 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr14_-_64971288 0.10 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr8_+_57124245 0.10 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
CHCHD7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr14_-_23822080 0.10 ENST00000397267.1
ENST00000354772.3
SLC22A17
solute carrier family 22, member 17
chr1_+_226250379 0.10 ENST00000366815.3
ENST00000366814.3
H3F3A
H3 histone, family 3A
chr8_-_74791051 0.10 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr18_+_12947981 0.10 ENST00000262124.11
SEH1L
SEH1-like (S. cerevisiae)
chr11_-_46638720 0.10 ENST00000326737.3
HARBI1
harbinger transposase derived 1
chr2_+_191208196 0.10 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr11_-_10315741 0.10 ENST00000256190.8
SBF2
SET binding factor 2
chr9_+_96338647 0.10 ENST00000359246.4
PHF2
PHD finger protein 2
chr12_-_49351148 0.10 ENST00000398092.4
ENST00000539611.1
RP11-302B13.5
ARF3
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr22_+_19706958 0.10 ENST00000395109.2
SEPT5
septin 5
chr1_+_51434357 0.10 ENST00000396148.1
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr15_-_65282232 0.10 ENST00000416889.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr1_-_98386543 0.09 ENST00000423006.2
ENST00000370192.3
ENST00000306031.5
DPYD
dihydropyrimidine dehydrogenase
chr4_-_100867864 0.09 ENST00000442697.2
DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr5_+_145583156 0.09 ENST00000265271.5
RBM27
RNA binding motif protein 27
chr4_+_103790120 0.09 ENST00000273986.4
CISD2
CDGSH iron sulfur domain 2
chr6_+_31543334 0.09 ENST00000449264.2
TNF
tumor necrosis factor
chr11_+_95523621 0.09 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
CEP57
centrosomal protein 57kDa
chr15_-_65282274 0.09 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr21_+_34602377 0.09 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr8_-_144679602 0.09 ENST00000526710.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr19_-_50836762 0.09 ENST00000474951.1
ENST00000391818.2
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR1_EGR4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.2 GO:0060733 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.1 0.1 GO:2000049 regulation of cell-cell adhesion mediated by cadherin(GO:2000047) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.6 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.5 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.1 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.1 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.1 GO:0051462 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.0 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.1 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0042414 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.1 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:1905073 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787)
0.0 0.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.7 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.0 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.3 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.0 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0014744 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of muscle adaptation(GO:0014744) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.0 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.0 GO:0061441 renal artery morphogenesis(GO:0061441)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0030862 positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.0 0.0 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.0 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.1 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0055048 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.0 GO:0098700 sequestering of neurotransmitter(GO:0042137) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.0 GO:0060129 forebrain dorsal/ventral pattern formation(GO:0021798) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.0 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.0 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.0 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.0 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.0 GO:2001302 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.0 GO:2000230 pancreatic stellate cell proliferation(GO:0072343) response to metformin(GO:1901558) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.0 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.0 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.1 GO:0071389 cellular response to mineralocorticoid stimulus(GO:0071389)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.3 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.2 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.3 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.3 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.2 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.0 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.0 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.0 0.1 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.0 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.0 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.0 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.0 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID VEGFR1 PATHWAY VEGFR1 specific signals

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex