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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EMX1

Z-value: 0.78

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Transcription factors associated with EMX1

Gene Symbol Gene ID Gene Info
EMX1
ENSG00000135638.9 empty spiracles homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX1hg19_v2_chr2_+_73144604_731446540.207.0e-01Click!

Activity profile of EMX1 motif

Sorted Z-values of EMX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_36245561 0.52 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_-_75488984 0.52 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
RP11-151D14.1
chrX_+_13671225 0.51 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr6_-_31107127 0.43 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr9_-_3469181 0.41 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr11_-_111649074 0.40 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr7_-_77427676 0.40 ENST00000257663.3
TMEM60
transmembrane protein 60
chr8_+_105235572 0.38 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr10_+_94451574 0.38 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr8_+_97773202 0.35 ENST00000519484.1
CPQ
carboxypeptidase Q
chr1_+_62439037 0.34 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr5_-_24645078 0.33 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr5_+_135394840 0.32 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr20_-_271304 0.32 ENST00000400269.3
ENST00000360321.2
C20orf96
chromosome 20 open reading frame 96
chr6_+_148593425 0.32 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr4_+_175204818 0.32 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr2_-_136678123 0.31 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr13_-_36050819 0.29 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr3_+_121774202 0.29 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr12_-_118796910 0.28 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr7_+_77428066 0.28 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr4_-_69111401 0.28 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr7_+_77428149 0.28 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr5_-_142077569 0.27 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1
fibroblast growth factor 1 (acidic)
chr2_-_203735586 0.26 ENST00000454326.1
ENST00000432273.1
ENST00000450143.1
ENST00000411681.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr6_+_139135648 0.26 ENST00000541398.1
ECT2L
epithelial cell transforming sequence 2 oncogene-like
chr4_-_74486109 0.26 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr12_+_44229846 0.26 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr17_-_46799872 0.26 ENST00000290294.3
PRAC1
prostate cancer susceptibility candidate 1
chr3_+_174158732 0.25 ENST00000434257.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr1_-_68698197 0.25 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr5_+_115177178 0.25 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr5_-_137374288 0.25 ENST00000514310.1
FAM13B
family with sequence similarity 13, member B
chr10_-_96829246 0.25 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr1_+_202317815 0.25 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr4_+_146402346 0.25 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr14_-_73360796 0.25 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr6_-_10435032 0.25 ENST00000491317.1
ENST00000496285.1
ENST00000479822.1
ENST00000487130.1
LINC00518
long intergenic non-protein coding RNA 518
chr7_+_23719749 0.24 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
FAM221A
family with sequence similarity 221, member A
chr4_-_89442940 0.24 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr2_-_227050079 0.24 ENST00000423838.1
AC068138.1
AC068138.1
chr12_+_107712173 0.24 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr4_-_147443043 0.24 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
SLC10A7
solute carrier family 10, member 7
chr10_-_93392811 0.24 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr4_+_169013666 0.23 ENST00000359299.3
ANXA10
annexin A10
chr7_+_12726623 0.23 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chr20_+_12989596 0.23 ENST00000434210.1
ENST00000399002.2
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr6_-_109702885 0.23 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr7_+_6655225 0.22 ENST00000457543.3
ZNF853
zinc finger protein 853
chrX_+_102024075 0.22 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
LINC00630
long intergenic non-protein coding RNA 630
chr2_-_102003987 0.22 ENST00000324768.5
CREG2
cellular repressor of E1A-stimulated genes 2
chr17_+_48823975 0.22 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr8_-_17533838 0.22 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr7_-_27169801 0.20 ENST00000511914.1
HOXA4
homeobox A4
chr4_+_183065793 0.20 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr2_+_171034646 0.20 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr5_+_36608422 0.20 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_15815626 0.20 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr4_-_89205879 0.20 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr7_+_130126165 0.20 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr11_-_104905840 0.20 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr1_-_68698222 0.20 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr7_+_116660246 0.19 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr14_+_67831576 0.19 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr3_-_180397256 0.19 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr12_-_118796971 0.19 ENST00000542902.1
TAOK3
TAO kinase 3
chr10_-_23633720 0.19 ENST00000323327.4
C10orf67
chromosome 10 open reading frame 67
chr14_-_70883708 0.19 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr19_+_37862054 0.19 ENST00000483919.1
ENST00000588911.1
ENST00000436120.2
ENST00000587349.1
ZNF527
zinc finger protein 527
chr8_+_70404996 0.19 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr7_-_83278322 0.19 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr17_-_39123144 0.19 ENST00000355612.2
KRT39
keratin 39
chr3_+_156799587 0.19 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr7_-_111032971 0.19 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr6_+_130339710 0.19 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr19_-_14064114 0.18 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr2_-_207082748 0.18 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr10_-_128110441 0.18 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr4_+_105828492 0.18 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr14_-_51027838 0.18 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr19_-_12889226 0.18 ENST00000589400.1
ENST00000590839.1
ENST00000592079.1
HOOK2
hook microtubule-tethering protein 2
chr3_-_123339343 0.18 ENST00000578202.1
MYLK
myosin light chain kinase
chr14_+_32798547 0.18 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr8_+_42396274 0.18 ENST00000438528.3
SMIM19
small integral membrane protein 19
chr20_+_12989895 0.18 ENST00000450297.1
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr11_-_96076334 0.18 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr12_+_16500599 0.18 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr20_+_12989822 0.17 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr12_+_16500571 0.17 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr10_+_91461337 0.17 ENST00000260753.4
ENST00000416354.1
ENST00000394289.2
ENST00000371728.3
KIF20B
kinesin family member 20B
chr3_-_151034734 0.17 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr5_+_53751445 0.17 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr1_-_151965048 0.16 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr15_+_96904487 0.16 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr7_+_93652116 0.16 ENST00000415536.1
AC003092.1
AC003092.1
chr6_+_153552455 0.16 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr19_-_58951496 0.16 ENST00000254166.3
ZNF132
zinc finger protein 132
chr12_+_16500037 0.16 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chrX_-_46187069 0.16 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr16_-_53737722 0.16 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr12_-_50616382 0.16 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr5_-_148929848 0.16 ENST00000504676.1
ENST00000515435.1
CSNK1A1
casein kinase 1, alpha 1
chrX_+_134654540 0.16 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr8_-_90996837 0.16 ENST00000519426.1
ENST00000265433.3
NBN
nibrin
chr16_-_66764119 0.16 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr7_+_36450169 0.16 ENST00000428612.1
ANLN
anillin, actin binding protein
chr12_+_64798826 0.16 ENST00000540203.1
XPOT
exportin, tRNA
chr15_-_55562451 0.15 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr4_+_86525299 0.15 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr16_-_66864806 0.15 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr14_-_21737551 0.15 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr20_-_23860373 0.15 ENST00000304710.4
CST5
cystatin D
chr5_-_74162605 0.15 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A
family with sequence similarity 169, member A
chr5_+_36606700 0.15 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_36608280 0.15 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_38670897 0.15 ENST00000373365.4
GLO1
glyoxalase I
chr1_-_151798546 0.15 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr12_+_41136144 0.15 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr10_+_5454505 0.15 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr1_-_151762943 0.14 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH
tudor and KH domain containing
chr10_+_111765562 0.14 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr3_+_152552685 0.14 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr16_-_53737795 0.14 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr17_-_74163159 0.14 ENST00000591615.1
RNF157
ring finger protein 157
chr11_-_107729887 0.14 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr4_+_169633310 0.14 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr12_-_42878101 0.14 ENST00000552108.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr12_-_25348007 0.14 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr6_-_111804905 0.14 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr14_+_85994943 0.14 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr7_-_111424462 0.14 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr11_+_112041253 0.14 ENST00000532612.1
AP002884.3
AP002884.3
chr1_+_236958554 0.14 ENST00000366577.5
ENST00000418145.2
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
chrX_-_13835147 0.13 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr7_+_130126012 0.13 ENST00000341441.5
MEST
mesoderm specific transcript
chr1_-_2461684 0.13 ENST00000378453.3
HES5
hes family bHLH transcription factor 5
chr4_-_74486347 0.13 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chrX_+_22050546 0.13 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr1_+_202317855 0.13 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr10_-_28571015 0.13 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr9_+_26956371 0.13 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr7_+_115862858 0.13 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr5_-_95297534 0.13 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chrX_+_105855160 0.13 ENST00000372544.2
ENST00000372548.4
CXorf57
chromosome X open reading frame 57
chr2_+_197577841 0.13 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chrX_-_106243451 0.13 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr11_+_100862811 0.13 ENST00000303130.2
TMEM133
transmembrane protein 133
chr11_-_118134997 0.13 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr11_+_27015628 0.13 ENST00000318627.2
FIBIN
fin bud initiation factor homolog (zebrafish)
chr11_-_118023490 0.13 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr1_-_157746909 0.13 ENST00000392274.3
ENST00000361516.3
ENST00000368181.4
FCRL2
Fc receptor-like 2
chr1_-_205719295 0.12 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr18_+_32173276 0.12 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr2_+_29320571 0.12 ENST00000401605.1
ENST00000401617.2
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr8_-_116504448 0.12 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr14_-_21737610 0.12 ENST00000320084.7
ENST00000449098.1
ENST00000336053.6
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr11_+_33061543 0.12 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr12_+_106751436 0.12 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr13_-_41593425 0.12 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr5_+_68860949 0.12 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chrX_-_107334790 0.12 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr15_-_72565340 0.12 ENST00000568360.1
PARP6
poly (ADP-ribose) polymerase family, member 6
chr3_+_186353756 0.12 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr15_-_65903407 0.12 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
VWA9
von Willebrand factor A domain containing 9
chr3_-_168865522 0.12 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr5_-_159846066 0.12 ENST00000519349.1
ENST00000520664.1
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr7_+_12727250 0.12 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr9_+_70856899 0.12 ENST00000377342.5
ENST00000478048.1
CBWD3
COBW domain containing 3
chr12_+_128399965 0.11 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr4_+_129732419 0.11 ENST00000510308.1
PHF17
jade family PHD finger 1
chr14_+_52313833 0.11 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr10_-_27529486 0.11 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr17_+_33914424 0.11 ENST00000590432.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr11_+_77532155 0.11 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
AAMDC
adipogenesis associated, Mth938 domain containing
chr12_+_32638897 0.11 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr12_-_22063787 0.11 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr19_-_56110859 0.11 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr1_-_109935819 0.11 ENST00000538502.1
SORT1
sortilin 1
chr2_+_179184955 0.11 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr1_+_160370344 0.11 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr10_-_116418053 0.11 ENST00000277895.5
ABLIM1
actin binding LIM protein 1
chr8_-_101963482 0.11 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr16_+_57279004 0.11 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr9_+_109685630 0.11 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr5_-_16509101 0.11 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr17_+_79495397 0.11 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr18_-_33709268 0.11 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr4_-_74486217 0.11 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr12_-_88974236 0.11 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr2_-_99871570 0.11 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr15_+_86087267 0.11 ENST00000558166.1
AKAP13
A kinase (PRKA) anchor protein 13
chrX_-_118986911 0.10 ENST00000276201.2
ENST00000345865.2
UPF3B
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr3_+_107364769 0.10 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr1_+_210501589 0.10 ENST00000413764.2
ENST00000541565.1
HHAT
hedgehog acyltransferase
chr9_+_26956474 0.10 ENST00000429045.2
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr10_-_71169031 0.10 ENST00000373307.1
TACR2
tachykinin receptor 2
chr4_+_146539415 0.10 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr17_-_55911970 0.10 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
RP11-60A24.3
chr14_-_23652849 0.10 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr13_+_36050881 0.10 ENST00000537702.1
NBEA
neurobeachin

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:0000921 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.0 0.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.3 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.0 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) regulation of penile erection(GO:0060405)
0.0 0.1 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:0035106 negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106)
0.0 0.6 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.4 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.3 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.0 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0043584 nose development(GO:0043584)
0.0 0.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.0 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:1903717 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.0 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.0 GO:1904640 response to methionine(GO:1904640)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.0 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.3 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.0 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway