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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EOMES

Z-value: 0.86

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Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
EOMES
ENSG00000163508.8 eomesodermin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EOMEShg19_v2_chr3_-_27763803_27763822-0.572.4e-01Click!

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_30948600 0.64 ENST00000550292.1
LINC00941
long intergenic non-protein coding RNA 941
chr17_-_18585131 0.59 ENST00000443457.1
ENST00000583002.1
ZNF286B
zinc finger protein 286B
chr6_-_86303833 0.58 ENST00000505648.1
SNX14
sorting nexin 14
chr5_+_443280 0.58 ENST00000508022.1
EXOC3
exocyst complex component 3
chr10_+_103986085 0.56 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr6_-_86303523 0.50 ENST00000513865.1
ENST00000369627.2
ENST00000514419.1
ENST00000509338.1
ENST00000314673.3
ENST00000346348.3
SNX14
sorting nexin 14
chr1_-_167906277 0.49 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr5_+_56205878 0.42 ENST00000423328.1
SETD9
SET domain containing 9
chr3_-_143567262 0.39 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr2_-_192015697 0.37 ENST00000409995.1
STAT4
signal transducer and activator of transcription 4
chr16_+_24550857 0.35 ENST00000568015.1
RBBP6
retinoblastoma binding protein 6
chr1_+_219347186 0.33 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr17_+_47439733 0.31 ENST00000507337.1
RP11-1079K10.3
RP11-1079K10.3
chr1_+_60280458 0.31 ENST00000455990.1
ENST00000371208.3
HOOK1
hook microtubule-tethering protein 1
chr2_+_230787213 0.29 ENST00000409992.1
FBXO36
F-box protein 36
chr14_-_55658323 0.29 ENST00000554067.1
ENST00000247191.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chrX_-_119695279 0.29 ENST00000336592.6
CUL4B
cullin 4B
chr19_+_39897943 0.28 ENST00000600033.1
ZFP36
ZFP36 ring finger protein
chr15_+_63414017 0.28 ENST00000413507.2
LACTB
lactamase, beta
chrX_+_106045891 0.27 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1D8B
TBC1 domain family, member 8B (with GRAM domain)
chr14_+_57857262 0.27 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr4_-_54930790 0.26 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr9_-_72374848 0.26 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
PTAR1
protein prenyltransferase alpha subunit repeat containing 1
chr2_-_99224915 0.26 ENST00000328709.3
ENST00000409997.1
COA5
cytochrome c oxidase assembly factor 5
chr14_+_32546145 0.26 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr2_-_148778258 0.26 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4
origin recognition complex, subunit 4
chr8_+_117778736 0.26 ENST00000309822.2
ENST00000357148.3
ENST00000517814.1
ENST00000517820.1
UTP23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr14_-_55658252 0.26 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr1_+_178694408 0.25 ENST00000324778.5
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr19_-_42894420 0.25 ENST00000597255.1
ENST00000222032.5
CNFN
cornifelin
chr11_-_102323489 0.25 ENST00000361236.3
TMEM123
transmembrane protein 123
chr6_-_73935163 0.25 ENST00000370388.3
KHDC1L
KH homology domain containing 1-like
chr14_-_64108125 0.24 ENST00000267522.3
WDR89
WD repeat domain 89
chr14_+_61995722 0.24 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr5_+_139028510 0.23 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5
CXXC finger protein 5
chr18_-_33047039 0.23 ENST00000591141.1
ENST00000586741.1
RP11-322E11.5
RP11-322E11.5
chr10_-_134145321 0.23 ENST00000368625.4
ENST00000368619.3
ENST00000456004.1
ENST00000368620.2
STK32C
serine/threonine kinase 32C
chr8_-_90996837 0.23 ENST00000519426.1
ENST00000265433.3
NBN
nibrin
chr5_+_32531893 0.23 ENST00000512913.1
SUB1
SUB1 homolog (S. cerevisiae)
chr1_+_27668505 0.23 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr12_+_65996599 0.22 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr1_+_100435535 0.22 ENST00000427993.2
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr8_-_90996459 0.22 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr17_-_4463856 0.22 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
GGT6
gamma-glutamyltransferase 6
chr11_-_66056596 0.21 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr2_-_152118352 0.21 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr9_+_132044730 0.21 ENST00000455981.1
RP11-344B5.2
RP11-344B5.2
chr1_-_146644122 0.21 ENST00000254101.3
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr14_-_53162361 0.21 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr1_-_244615425 0.20 ENST00000366535.3
ADSS
adenylosuccinate synthase
chr2_-_40006289 0.20 ENST00000260619.6
ENST00000454352.2
THUMPD2
THUMP domain containing 2
chr1_-_146644036 0.20 ENST00000425272.2
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr4_-_4291761 0.20 ENST00000513174.1
LYAR
Ly1 antibody reactive
chr8_+_86089619 0.20 ENST00000256117.5
ENST00000416274.2
E2F5
E2F transcription factor 5, p130-binding
chr2_+_45878407 0.19 ENST00000421201.1
PRKCE
protein kinase C, epsilon
chr11_+_1860832 0.19 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr2_-_148778323 0.19 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr5_+_110073853 0.19 ENST00000513807.1
ENST00000509442.2
SLC25A46
solute carrier family 25, member 46
chr3_-_88108192 0.19 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr6_-_116989916 0.19 ENST00000368576.3
ENST00000368573.1
ZUFSP
zinc finger with UFM1-specific peptidase domain
chr14_+_32546485 0.19 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr22_-_37545972 0.18 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr1_+_150229554 0.18 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr5_-_93447333 0.18 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr11_-_64052111 0.18 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BAD
BCL2-associated agonist of cell death
chr1_-_193029192 0.18 ENST00000417752.1
ENST00000367452.4
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr6_+_154360616 0.17 ENST00000229768.5
ENST00000419506.2
ENST00000524163.1
ENST00000414028.2
ENST00000435918.2
ENST00000337049.4
OPRM1
opioid receptor, mu 1
chr1_-_228291136 0.17 ENST00000272139.4
C1orf35
chromosome 1 open reading frame 35
chr14_+_32546274 0.17 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr3_-_43663519 0.17 ENST00000427171.1
ENST00000292246.3
ANO10
anoctamin 10
chr15_+_63413990 0.17 ENST00000261893.4
LACTB
lactamase, beta
chr1_-_109203997 0.17 ENST00000370032.5
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr3_-_43147431 0.17 ENST00000441964.1
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr10_-_13342051 0.17 ENST00000479604.1
PHYH
phytanoyl-CoA 2-hydroxylase
chr12_-_6579808 0.17 ENST00000535180.1
ENST00000400911.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr17_-_8066843 0.17 ENST00000404970.3
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr21_-_47604318 0.17 ENST00000291672.5
ENST00000330205.6
SPATC1L
spermatogenesis and centriole associated 1-like
chr7_-_91875358 0.17 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1
KRIT1, ankyrin repeat containing
chr1_+_196788887 0.17 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr1_+_15256230 0.16 ENST00000376028.4
ENST00000400798.2
KAZN
kazrin, periplakin interacting protein
chr19_-_36499521 0.16 ENST00000397428.3
ENST00000503121.1
ENST00000340477.5
ENST00000324444.3
ENST00000490730.1
SYNE4
spectrin repeat containing, nuclear envelope family member 4
chr3_-_49893907 0.16 ENST00000482582.1
TRAIP
TRAF interacting protein
chr12_+_65563329 0.16 ENST00000308330.2
LEMD3
LEM domain containing 3
chrX_-_54070388 0.16 ENST00000415025.1
PHF8
PHD finger protein 8
chr22_-_46373004 0.15 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr1_+_172502244 0.15 ENST00000610051.1
SUCO
SUN domain containing ossification factor
chr19_-_18391708 0.15 ENST00000600972.1
JUND
jun D proto-oncogene
chr6_-_109703634 0.15 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164
CD164 molecule, sialomucin
chr15_-_52970820 0.15 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr19_+_49956426 0.15 ENST00000293350.4
ENST00000540132.1
ENST00000455361.2
ENST00000433981.2
ALDH16A1
aldehyde dehydrogenase 16 family, member A1
chr2_-_179315786 0.15 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr17_-_17723746 0.15 ENST00000577897.1
SREBF1
sterol regulatory element binding transcription factor 1
chr11_+_47270475 0.15 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr8_-_8318847 0.15 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr1_+_186344945 0.14 ENST00000419367.3
ENST00000287859.6
C1orf27
chromosome 1 open reading frame 27
chr19_+_41107249 0.14 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr17_-_60005365 0.14 ENST00000444766.3
INTS2
integrator complex subunit 2
chr17_+_74723031 0.14 ENST00000586200.1
METTL23
methyltransferase like 23
chr9_+_2017063 0.14 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_44379944 0.14 ENST00000396078.3
ENST00000342649.4
TCAIM
T cell activation inhibitor, mitochondrial
chr18_+_76829441 0.14 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr1_-_226065330 0.14 ENST00000436966.1
TMEM63A
transmembrane protein 63A
chr4_+_8321882 0.14 ENST00000509453.1
ENST00000503186.1
RP11-774O3.2
RP11-774O3.1
RP11-774O3.2
RP11-774O3.1
chr1_+_172502336 0.14 ENST00000263688.3
SUCO
SUN domain containing ossification factor
chr18_+_2655849 0.14 ENST00000261598.8
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr20_-_35274548 0.14 ENST00000262866.4
SLA2
Src-like-adaptor 2
chr15_-_43029252 0.14 ENST00000563260.1
ENST00000356231.3
CDAN1
codanin 1
chr4_+_17812525 0.14 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr1_-_43751230 0.14 ENST00000523677.1
C1orf210
chromosome 1 open reading frame 210
chr2_+_61108650 0.13 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr9_+_37800758 0.13 ENST00000242323.7
DCAF10
DDB1 and CUL4 associated factor 10
chr5_+_61708582 0.13 ENST00000325324.6
IPO11
importin 11
chr3_-_182698381 0.13 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr10_-_103454876 0.13 ENST00000331272.7
FBXW4
F-box and WD repeat domain containing 4
chr2_+_201171268 0.13 ENST00000423749.1
ENST00000428692.1
ENST00000457757.1
ENST00000453663.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr2_-_161350305 0.13 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr18_+_2655692 0.13 ENST00000320876.6
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr19_+_7599597 0.13 ENST00000414982.3
ENST00000450331.3
PNPLA6
patatin-like phospholipase domain containing 6
chr7_-_66460563 0.13 ENST00000246868.2
SBDS
Shwachman-Bodian-Diamond syndrome
chr15_+_40532723 0.13 ENST00000558878.1
ENST00000558183.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr11_+_63655987 0.13 ENST00000509502.2
ENST00000512060.1
MARK2
MAP/microtubule affinity-regulating kinase 2
chr2_-_101767715 0.13 ENST00000376840.4
ENST00000409318.1
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr16_+_3162557 0.13 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
ZNF205
zinc finger protein 205
chr3_+_132379154 0.13 ENST00000468022.1
ENST00000473651.1
ENST00000494238.2
UBA5
ubiquitin-like modifier activating enzyme 5
chr1_+_162760513 0.12 ENST00000367915.1
ENST00000367917.3
ENST00000254521.3
ENST00000367913.1
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr3_+_111805182 0.12 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
C3orf52
chromosome 3 open reading frame 52
chr5_+_133562095 0.12 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr17_-_27949911 0.12 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6
coronin 6
chr4_-_129208030 0.12 ENST00000503872.1
PGRMC2
progesterone receptor membrane component 2
chr15_-_65426174 0.12 ENST00000204549.4
PDCD7
programmed cell death 7
chr1_+_26438289 0.12 ENST00000374271.4
ENST00000374269.1
PDIK1L
PDLIM1 interacting kinase 1 like
chr8_+_96037255 0.12 ENST00000286687.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr21_+_38445539 0.12 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr20_-_18038521 0.12 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chr2_-_74875432 0.12 ENST00000536235.1
ENST00000421985.1
M1AP
meiosis 1 associated protein
chr19_+_55897699 0.12 ENST00000558131.1
ENST00000558752.1
ENST00000458349.2
RPL28
ribosomal protein L28
chr2_-_235405168 0.12 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr17_-_17740287 0.12 ENST00000355815.4
ENST00000261646.5
SREBF1
sterol regulatory element binding transcription factor 1
chr14_-_89259080 0.12 ENST00000554922.1
ENST00000352093.5
EML5
echinoderm microtubule associated protein like 5
chr6_-_82957433 0.12 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr18_+_48556470 0.12 ENST00000589076.1
ENST00000590061.1
ENST00000591914.1
ENST00000342988.3
SMAD4
SMAD family member 4
chr16_-_3086927 0.12 ENST00000572449.1
CCDC64B
coiled-coil domain containing 64B
chr3_-_131221790 0.12 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
MRPL3
mitochondrial ribosomal protein L3
chr12_-_6579833 0.12 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr2_-_97523721 0.12 ENST00000393537.4
ANKRD39
ankyrin repeat domain 39
chr22_-_37584321 0.12 ENST00000397110.2
ENST00000337843.2
C1QTNF6
C1q and tumor necrosis factor related protein 6
chr17_-_62493131 0.12 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr17_-_77813186 0.12 ENST00000448310.1
ENST00000269397.4
CBX4
chromobox homolog 4
chr20_-_43150601 0.12 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
SERINC3
serine incorporator 3
chr8_+_81397846 0.12 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr3_-_122102065 0.12 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58
coiled-coil domain containing 58
chr12_+_54378849 0.12 ENST00000515593.1
HOXC10
homeobox C10
chr5_-_145483932 0.12 ENST00000311450.4
PLAC8L1
PLAC8-like 1
chr17_-_74533734 0.11 ENST00000589342.1
CYGB
cytoglobin
chr11_+_706595 0.11 ENST00000531348.1
ENST00000530636.1
EPS8L2
EPS8-like 2
chr12_+_31812121 0.11 ENST00000395763.3
METTL20
methyltransferase like 20
chr2_-_170430277 0.11 ENST00000438035.1
ENST00000453929.2
FASTKD1
FAST kinase domains 1
chr10_+_135340859 0.11 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr11_+_1860682 0.11 ENST00000381906.1
TNNI2
troponin I type 2 (skeletal, fast)
chr16_-_1429010 0.11 ENST00000513783.1
UNKL
unkempt family zinc finger-like
chr19_-_38085633 0.11 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
ZNF571
zinc finger protein 571
chr17_+_79989937 0.11 ENST00000580965.1
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr14_-_77843390 0.11 ENST00000216468.7
TMED8
transmembrane emp24 protein transport domain containing 8
chr5_-_94620239 0.11 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr20_+_327668 0.11 ENST00000382291.3
ENST00000609504.1
ENST00000382285.2
NRSN2
neurensin 2
chr19_-_34012674 0.11 ENST00000436370.3
ENST00000397032.4
ENST00000244137.7
PEPD
peptidase D
chr3_+_9944303 0.11 ENST00000421412.1
ENST00000295980.3
IL17RE
interleukin 17 receptor E
chr1_-_93426998 0.11 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr4_-_129207942 0.11 ENST00000503588.1
PGRMC2
progesterone receptor membrane component 2
chr11_+_47270436 0.11 ENST00000395397.3
ENST00000405576.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr3_-_43147549 0.10 ENST00000344697.2
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr9_+_139846708 0.10 ENST00000371633.3
LCN12
lipocalin 12
chr17_+_27895045 0.10 ENST00000580183.2
ENST00000578749.1
ENST00000582829.2
TP53I13
tumor protein p53 inducible protein 13
chr8_+_22429205 0.10 ENST00000520207.1
SORBS3
sorbin and SH3 domain containing 3
chr11_+_117947724 0.10 ENST00000534111.1
TMPRSS4
transmembrane protease, serine 4
chr7_+_87505544 0.10 ENST00000265728.1
DBF4
DBF4 homolog (S. cerevisiae)
chr1_-_184943610 0.10 ENST00000367511.3
FAM129A
family with sequence similarity 129, member A
chr18_+_76829385 0.10 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr13_-_73301819 0.10 ENST00000377818.3
MZT1
mitotic spindle organizing protein 1
chr11_+_65686728 0.10 ENST00000312515.2
ENST00000525501.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr17_-_79269067 0.10 ENST00000288439.5
ENST00000374759.3
SLC38A10
solute carrier family 38, member 10
chr19_+_55795493 0.10 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr3_-_135915401 0.10 ENST00000491050.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr19_-_3500635 0.10 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr22_-_50970506 0.10 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr1_-_149814478 0.10 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr19_+_49838653 0.10 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr1_+_28099700 0.10 ENST00000440806.2
STX12
syntaxin 12
chr19_+_7598890 0.10 ENST00000221249.6
ENST00000601668.1
ENST00000601001.1
PNPLA6
patatin-like phospholipase domain containing 6
chr6_+_74405501 0.10 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr17_-_38256973 0.10 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr11_-_66056478 0.10 ENST00000431556.2
ENST00000528575.1
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr16_-_21452040 0.10 ENST00000521589.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr7_+_30323923 0.09 ENST00000323037.4
ZNRF2
zinc and ring finger 2
chr3_-_183735651 0.09 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr11_+_537494 0.09 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr15_-_56757329 0.09 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr17_-_48133054 0.09 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr3_+_44379611 0.09 ENST00000383746.3
ENST00000417237.1
TCAIM
T cell activation inhibitor, mitochondrial
chr6_+_45389893 0.09 ENST00000371432.3
RUNX2
runt-related transcription factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.3 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 0.2 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1 0.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.2 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0035262 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) gonad morphogenesis(GO:0035262)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.2 GO:0060535 trachea cartilage morphogenesis(GO:0060535) inner medullary collecting duct development(GO:0072061)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.3 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0010728 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 1.1 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.3 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.3 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.2 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.0 GO:1901291 negative regulation of double-strand break repair via single-strand annealing(GO:1901291)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.4 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0034678 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.2 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.2 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.3 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.0 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.0 GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity(GO:0034039)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks