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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EPAS1_BCL3

Z-value: 1.23

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Transcription factors associated with EPAS1_BCL3

Gene Symbol Gene ID Gene Info
EPAS1
ENSG00000116016.9 endothelial PAS domain protein 1
BCL3
ENSG00000069399.8 BCL3 transcription coactivator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EPAS1hg19_v2_chr2_+_46524537_46524553-0.853.3e-02Click!
BCL3hg19_v2_chr19_+_45254529_45254578-0.315.6e-01Click!

Activity profile of EPAS1_BCL3 motif

Sorted Z-values of EPAS1_BCL3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_46283597 1.28 ENST00000451118.1
WI2-85898F10.1
WI2-85898F10.1
chr11_+_111808119 0.95 ENST00000531396.1
DIXDC1
DIX domain containing 1
chr11_-_75062730 0.81 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr5_-_119669160 0.80 ENST00000514240.1
CTC-552D5.1
CTC-552D5.1
chr1_-_152779104 0.77 ENST00000606576.1
ENST00000368768.1
LCE1C
late cornified envelope 1C
chr14_-_81902516 0.65 ENST00000554710.1
STON2
stonin 2
chr19_-_35626104 0.62 ENST00000310123.3
ENST00000392225.3
LGI4
leucine-rich repeat LGI family, member 4
chr9_+_46390277 0.61 ENST00000426006.1
FAM27D1
family with sequence similarity 27, member D1
chr11_+_73675873 0.60 ENST00000537753.1
ENST00000542350.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chrX_+_1387693 0.59 ENST00000381529.3
ENST00000432318.2
ENST00000361536.3
ENST00000501036.2
ENST00000381524.3
ENST00000412290.1
CSF2RA
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr14_+_91709103 0.59 ENST00000553725.1
CTD-2547L24.3
HCG1816139; Uncharacterized protein
chr16_-_11367452 0.57 ENST00000327157.2
PRM3
protamine 3
chr14_-_71107921 0.54 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr16_+_82068873 0.49 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr4_+_105828492 0.47 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chrX_-_20134990 0.47 ENST00000379651.3
ENST00000443379.3
ENST00000379643.5
MAP7D2
MAP7 domain containing 2
chr19_-_47975106 0.45 ENST00000539381.1
ENST00000594353.1
ENST00000542837.1
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr4_+_105828537 0.43 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr1_-_240775447 0.40 ENST00000318160.4
GREM2
gremlin 2, DAN family BMP antagonist
chr22_-_29075853 0.40 ENST00000397906.2
TTC28
tetratricopeptide repeat domain 28
chr1_-_23751189 0.39 ENST00000374601.3
ENST00000450454.2
TCEA3
transcription elongation factor A (SII), 3
chr19_-_47975417 0.39 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr19_+_18530146 0.39 ENST00000348495.6
ENST00000270061.7
SSBP4
single stranded DNA binding protein 4
chr6_-_4347271 0.39 ENST00000437430.2
RP3-527G5.1
RP3-527G5.1
chr3_+_187957646 0.38 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chrX_-_111923145 0.38 ENST00000371968.3
ENST00000536453.1
LHFPL1
lipoma HMGIC fusion partner-like 1
chr19_-_44405623 0.38 ENST00000591815.1
RP11-15A1.3
RP11-15A1.3
chr1_+_174769006 0.38 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr5_-_142065612 0.36 ENST00000360966.5
ENST00000411960.1
FGF1
fibroblast growth factor 1 (acidic)
chr19_+_40195101 0.35 ENST00000360675.3
ENST00000601802.1
LGALS14
lectin, galactoside-binding, soluble, 14
chr1_-_150208291 0.33 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_+_121088291 0.33 ENST00000351200.2
CABP1
calcium binding protein 1
chr1_+_81106951 0.32 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr9_+_2017063 0.32 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr20_+_9049742 0.32 ENST00000437503.1
PLCB4
phospholipase C, beta 4
chr17_+_38119216 0.32 ENST00000301659.4
GSDMA
gasdermin A
chr19_+_14491948 0.31 ENST00000358600.3
CD97
CD97 molecule
chr7_-_117512264 0.30 ENST00000454375.1
CTTNBP2
cortactin binding protein 2
chr6_+_31620191 0.30 ENST00000375918.2
ENST00000375920.4
APOM
apolipoprotein M
chr21_+_35553045 0.30 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr1_+_110453514 0.28 ENST00000369802.3
ENST00000420111.2
CSF1
colony stimulating factor 1 (macrophage)
chrX_-_30871004 0.27 ENST00000378928.1
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr1_+_110198714 0.27 ENST00000336075.5
ENST00000326729.5
GSTM4
glutathione S-transferase mu 4
chr2_+_74229812 0.27 ENST00000305799.7
TET3
tet methylcytosine dioxygenase 3
chr8_+_41386725 0.27 ENST00000276533.3
ENST00000520710.1
ENST00000518671.1
GINS4
GINS complex subunit 4 (Sld5 homolog)
chr6_-_40555176 0.27 ENST00000338305.6
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr11_-_75062829 0.26 ENST00000393505.4
ARRB1
arrestin, beta 1
chr2_+_120436760 0.26 ENST00000445518.1
ENST00000409951.1
TMEM177
transmembrane protein 177
chr11_+_128761220 0.26 ENST00000529694.1
KCNJ5
potassium inwardly-rectifying channel, subfamily J, member 5
chr4_-_168155577 0.26 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr11_+_94371204 0.26 ENST00000438416.2
RP11-867G2.5
RP11-867G2.5
chr16_-_70719925 0.25 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr18_+_1099004 0.25 ENST00000581556.1
RP11-78F17.1
RP11-78F17.1
chr2_+_74881398 0.25 ENST00000339773.5
ENST00000434486.1
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr16_-_79804394 0.25 ENST00000567993.1
RP11-345M22.2
RP11-345M22.2
chr1_-_45308616 0.24 ENST00000447098.2
ENST00000372192.3
PTCH2
patched 2
chr7_+_121513374 0.24 ENST00000449182.1
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr4_+_86749045 0.24 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr9_+_34652164 0.24 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr4_-_177116772 0.23 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr19_-_52227221 0.23 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr4_-_146859623 0.23 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr9_+_125315391 0.23 ENST00000373688.2
OR1N2
olfactory receptor, family 1, subfamily N, member 2
chr12_+_56546363 0.23 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr13_-_103426081 0.23 ENST00000376022.1
ENST00000376021.4
TEX30
testis expressed 30
chr3_-_133748758 0.23 ENST00000493729.1
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr7_-_76039000 0.23 ENST00000275560.3
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr5_-_169407744 0.23 ENST00000377365.3
FAM196B
family with sequence similarity 196, member B
chr17_+_79369249 0.22 ENST00000574717.2
RP11-1055B8.6
Uncharacterized protein
chr19_-_16284286 0.22 ENST00000379859.3
ENST00000269878.4
CIB3
calcium and integrin binding family member 3
chr19_+_35741466 0.22 ENST00000599658.1
LSR
lipolysis stimulated lipoprotein receptor
chr2_+_33701684 0.22 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr20_-_61733657 0.22 ENST00000608031.1
ENST00000447910.2
HAR1B
highly accelerated region 1B (non-protein coding)
chr4_-_113627966 0.22 ENST00000505632.1
RP11-148B6.2
RP11-148B6.2
chr10_-_47222824 0.21 ENST00000355232.3
AGAP10
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr1_+_247712383 0.21 ENST00000366488.4
ENST00000536561.1
GCSAML
germinal center-associated, signaling and motility-like
chr2_+_33701707 0.21 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr13_+_51913819 0.21 ENST00000419898.2
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr17_-_75878647 0.21 ENST00000374983.2
FLJ45079
FLJ45079
chr15_-_79576156 0.21 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4
RP11-17L5.4
chr19_-_17007026 0.21 ENST00000598792.1
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr18_-_74534232 0.21 ENST00000585258.1
RP11-162A12.2
Uncharacterized protein
chr2_+_120436733 0.21 ENST00000401466.1
ENST00000424086.1
ENST00000272521.6
TMEM177
transmembrane protein 177
chr1_+_209757051 0.20 ENST00000009105.1
ENST00000423146.1
ENST00000361322.2
CAMK1G
calcium/calmodulin-dependent protein kinase IG
chrX_-_15288154 0.20 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9
ankyrin repeat and SOCS box containing 9
chr3_+_185080908 0.20 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr4_+_331578 0.20 ENST00000512994.1
ZNF141
zinc finger protein 141
chr1_+_110198689 0.20 ENST00000369836.4
GSTM4
glutathione S-transferase mu 4
chr13_+_31309645 0.20 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr1_-_31230650 0.19 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr11_-_74022658 0.19 ENST00000427714.2
ENST00000331597.4
P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr20_+_34680698 0.19 ENST00000447825.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr3_-_184870751 0.19 ENST00000335012.2
C3orf70
chromosome 3 open reading frame 70
chr21_+_37507210 0.19 ENST00000290354.5
CBR3
carbonyl reductase 3
chr3_-_9291063 0.19 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr10_-_93669233 0.18 ENST00000311575.5
FGFBP3
fibroblast growth factor binding protein 3
chr11_-_89224638 0.18 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr2_+_102618428 0.18 ENST00000457817.1
IL1R2
interleukin 1 receptor, type II
chr3_-_49459878 0.18 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr2_+_105760549 0.18 ENST00000436841.1
ENST00000452037.1
ENST00000438148.1
AC104655.3
AC104655.3
chr19_+_55795493 0.18 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr4_-_48082192 0.18 ENST00000507351.1
TXK
TXK tyrosine kinase
chrX_-_133792480 0.18 ENST00000359237.4
PLAC1
placenta-specific 1
chrX_+_3189861 0.18 ENST00000457435.1
ENST00000420429.2
CXorf28
chromosome X open reading frame 28
chr11_+_31833939 0.18 ENST00000530348.1
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr17_-_76732928 0.18 ENST00000589768.1
CYTH1
cytohesin 1
chr2_+_74881432 0.18 ENST00000453930.1
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr14_-_85996332 0.17 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr18_+_61254221 0.17 ENST00000431153.1
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr2_+_102686820 0.17 ENST00000409929.1
ENST00000424272.1
IL1R1
interleukin 1 receptor, type I
chr17_-_74533734 0.17 ENST00000589342.1
CYGB
cytoglobin
chr1_-_221915418 0.17 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr3_+_112930946 0.17 ENST00000462425.1
BOC
BOC cell adhesion associated, oncogene regulated
chr2_-_238499131 0.17 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr10_-_30348439 0.17 ENST00000375377.1
KIAA1462
KIAA1462
chr19_-_16582815 0.17 ENST00000455140.2
ENST00000248070.6
ENST00000594975.1
EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
chr1_+_61548374 0.17 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA
nuclear factor I/A
chr17_-_17109579 0.17 ENST00000321560.3
PLD6
phospholipase D family, member 6
chr19_+_45445524 0.17 ENST00000591600.1
APOC4
apolipoprotein C-IV
chr17_+_73750699 0.17 ENST00000584939.1
ITGB4
integrin, beta 4
chr8_-_41508855 0.17 ENST00000518699.2
NKX6-3
NK6 homeobox 3
chr18_+_6729725 0.17 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr17_+_1665306 0.16 ENST00000571360.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr9_-_4299874 0.16 ENST00000381971.3
ENST00000477901.1
GLIS3
GLIS family zinc finger 3
chr19_+_52848659 0.16 ENST00000327920.8
ZNF610
zinc finger protein 610
chr19_-_56988677 0.16 ENST00000504904.3
ENST00000292069.6
ZNF667
zinc finger protein 667
chr22_-_37505449 0.16 ENST00000406725.1
TMPRSS6
transmembrane protease, serine 6
chr12_-_57504975 0.16 ENST00000553397.1
ENST00000556259.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr3_-_193272741 0.16 ENST00000392443.3
ATP13A4
ATPase type 13A4
chr17_-_30185971 0.16 ENST00000378634.2
COPRS
coordinator of PRMT5, differentiation stimulator
chr1_+_32712815 0.16 ENST00000373582.3
FAM167B
family with sequence similarity 167, member B
chr22_-_37880543 0.16 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr22_+_32439019 0.16 ENST00000266088.4
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr22_+_24990746 0.16 ENST00000456869.1
ENST00000411974.1
GGT1
gamma-glutamyltransferase 1
chr3_-_195310802 0.16 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr3_-_45017609 0.16 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
ZDHHC3
zinc finger, DHHC-type containing 3
chr5_-_96143602 0.15 ENST00000443439.2
ENST00000503921.1
ENST00000508227.1
ENST00000507154.1
ERAP1
endoplasmic reticulum aminopeptidase 1
chr7_+_95401851 0.15 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr12_-_62585203 0.15 ENST00000551449.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr19_-_8675559 0.15 ENST00000597188.1
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr4_-_186732241 0.15 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr14_+_104177607 0.15 ENST00000429169.1
AL049840.1
Uncharacterized protein; cDNA FLJ53535
chrX_-_142722897 0.15 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr3_-_167813672 0.15 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr8_-_38386175 0.15 ENST00000437935.2
ENST00000358138.1
C8orf86
chromosome 8 open reading frame 86
chrX_-_119445306 0.15 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A
transmembrane protein 255A
chr12_+_4829507 0.15 ENST00000252318.2
GALNT8
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)
chr10_+_123923205 0.15 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr1_-_113160826 0.15 ENST00000538187.1
ENST00000369664.1
ST7L
suppression of tumorigenicity 7 like
chr19_+_58838369 0.15 ENST00000329665.4
ZSCAN22
zinc finger and SCAN domain containing 22
chr4_-_70626314 0.15 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr11_-_89224488 0.15 ENST00000534731.1
ENST00000527626.1
NOX4
NADPH oxidase 4
chr7_+_125078119 0.15 ENST00000458437.1
ENST00000415896.1
RP11-807H17.1
RP11-807H17.1
chr19_+_782755 0.15 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr22_+_41601209 0.14 ENST00000216237.5
L3MBTL2
l(3)mbt-like 2 (Drosophila)
chr5_-_58652788 0.14 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_+_242673994 0.14 ENST00000321264.4
ENST00000537090.1
ENST00000403782.1
ENST00000342518.6
D2HGDH
D-2-hydroxyglutarate dehydrogenase
chr3_+_174577070 0.14 ENST00000454872.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr2_+_45878407 0.14 ENST00000421201.1
PRKCE
protein kinase C, epsilon
chr3_+_154958715 0.14 ENST00000462531.1
ENST00000490497.1
RP11-451G4.1
RP11-451G4.1
chr13_-_103426112 0.14 ENST00000376032.4
ENST00000376029.3
TEX30
testis expressed 30
chr5_+_32711419 0.14 ENST00000265074.8
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr4_-_106817137 0.14 ENST00000510876.1
INTS12
integrator complex subunit 12
chr6_-_90121789 0.14 ENST00000359203.3
RRAGD
Ras-related GTP binding D
chr19_+_41509851 0.14 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr9_+_127020202 0.14 ENST00000373600.3
ENST00000320246.5
NEK6
NIMA-related kinase 6
chr1_+_223354486 0.14 ENST00000446145.1
RP11-239E10.3
RP11-239E10.3
chr2_-_42180940 0.14 ENST00000378711.2
C2orf91
chromosome 2 open reading frame 91
chr14_+_71108460 0.14 ENST00000256367.2
TTC9
tetratricopeptide repeat domain 9
chr19_-_37096139 0.14 ENST00000585983.1
ENST00000585960.1
ENST00000586115.1
ZNF529
zinc finger protein 529
chr15_+_40544749 0.14 ENST00000559617.1
ENST00000560684.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr19_+_14492247 0.14 ENST00000357355.3
ENST00000592261.2
ENST00000242786.5
CD97
CD97 molecule
chr11_+_111169565 0.14 ENST00000528846.1
COLCA2
colorectal cancer associated 2
chr10_+_115939008 0.14 ENST00000369282.1
ENST00000251864.2
ENST00000369281.2
ENST00000422662.1
TDRD1
tudor domain containing 1
chr17_-_78194147 0.13 ENST00000534910.1
ENST00000326317.6
SGSH
N-sulfoglucosamine sulfohydrolase
chr6_-_11807277 0.13 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr15_+_48009541 0.13 ENST00000536845.2
ENST00000558816.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr10_+_5566916 0.13 ENST00000315238.1
CALML3
calmodulin-like 3
chr19_-_36705547 0.13 ENST00000304116.5
ZNF565
zinc finger protein 565
chr19_+_46009837 0.13 ENST00000589627.1
VASP
vasodilator-stimulated phosphoprotein
chr19_+_46171464 0.13 ENST00000590918.1
ENST00000263281.3
ENST00000304207.8
GIPR
gastric inhibitory polypeptide receptor
chr18_-_21242833 0.13 ENST00000586087.1
ENST00000592179.1
ANKRD29
ankyrin repeat domain 29
chr4_-_70725856 0.13 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr2_-_188312971 0.13 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr5_-_142065223 0.13 ENST00000378046.1
FGF1
fibroblast growth factor 1 (acidic)
chr12_-_56326402 0.13 ENST00000547925.1
WIBG
within bgcn homolog (Drosophila)
chr12_+_4385230 0.13 ENST00000536537.1
CCND2
cyclin D2
chr8_-_143696833 0.13 ENST00000356613.2
ARC
activity-regulated cytoskeleton-associated protein
chr6_-_150212029 0.13 ENST00000529948.1
ENST00000357183.4
ENST00000367363.3
RAET1E
retinoic acid early transcript 1E
chr17_+_48243352 0.13 ENST00000344627.6
ENST00000262018.3
ENST00000543315.1
ENST00000451235.2
ENST00000511303.1
SGCA
sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
chr15_+_42694573 0.13 ENST00000397200.4
ENST00000569827.1
CAPN3
calpain 3, (p94)
chr3_-_50374869 0.13 ENST00000327761.3
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr21_-_31311818 0.13 ENST00000535441.1
ENST00000309434.7
ENST00000327783.4
ENST00000389124.2
ENST00000389125.3
ENST00000399913.1
GRIK1
glutamate receptor, ionotropic, kainate 1
chr3_-_193272874 0.13 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr9_-_101471479 0.13 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chrX_-_101397433 0.13 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr6_-_41122063 0.12 ENST00000426005.2
ENST00000437044.2
ENST00000373127.4
TREML1
triggering receptor expressed on myeloid cells-like 1
chr3_-_15563229 0.12 ENST00000383786.5
ENST00000383787.2
ENST00000383785.2
ENST00000383788.5
ENST00000603808.1
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr14_-_54420133 0.12 ENST00000559501.1
ENST00000558984.1
BMP4
bone morphogenetic protein 4
chr7_-_83824449 0.12 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.6 GO:1903974 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.1 0.5 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.1 1.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.3 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.7 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.1 0.6 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.1 0.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.2 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.2 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.2 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.2 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.2 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0072197 ureter morphogenesis(GO:0072197)
0.0 0.1 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.0 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.1 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:2000283 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.3 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0014740 regulation of muscle hyperplasia(GO:0014738) negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.3 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.2 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:1904252 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) negative regulation of bile acid biosynthetic process(GO:0070858) acinar cell differentiation(GO:0090425) negative regulation of bile acid metabolic process(GO:1904252) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.6 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.0 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.0 GO:0048880 sensory system development(GO:0048880)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.0 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.0 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.3 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.6 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.0 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.0 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.0 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.0 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.4 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0048263 determination of dorsal identity(GO:0048263)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 0.3 GO:0072534 perineuronal net(GO:0072534)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.0 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031896 vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.1 0.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.2 GO:0016826 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 0.5 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.0 0.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0030109 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.6 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.0 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.7 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac