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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ESRRB_ESRRG

Z-value: 1.21

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Transcription factors associated with ESRRB_ESRRG

Gene Symbol Gene ID Gene Info
ESRRB
ENSG00000119715.10 estrogen related receptor beta
ESRRG
ENSG00000196482.12 estrogen related receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESRRBhg19_v2_chr14_+_76776957_76777061-0.701.2e-01Click!
ESRRGhg19_v2_chr1_-_216896780_2168968000.503.1e-01Click!

Activity profile of ESRRB_ESRRG motif

Sorted Z-values of ESRRB_ESRRG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_74864386 1.38 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr6_-_72129806 1.16 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr16_+_58535372 1.04 ENST00000566656.1
ENST00000566618.1
NDRG4
NDRG family member 4
chr19_+_42824511 1.04 ENST00000601644.1
TMEM145
transmembrane protein 145
chrX_+_109602039 0.69 ENST00000520821.1
RGAG1
retrotransposon gag domain containing 1
chr15_+_67814008 0.66 ENST00000557807.1
C15orf61
chromosome 15 open reading frame 61
chr14_+_21492331 0.62 ENST00000533984.1
ENST00000532213.2
AL161668.5
AL161668.5
chr14_-_31889737 0.62 ENST00000382464.2
HEATR5A
HEAT repeat containing 5A
chr1_+_16083098 0.62 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr2_+_228678550 0.58 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr19_+_589893 0.56 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr6_+_31916733 0.51 ENST00000483004.1
CFB
complement factor B
chr17_+_76037081 0.49 ENST00000588549.1
TNRC6C
trinucleotide repeat containing 6C
chr1_-_153433120 0.48 ENST00000368723.3
S100A7
S100 calcium binding protein A7
chr17_+_73455788 0.46 ENST00000581519.1
KIAA0195
KIAA0195
chr7_+_76107444 0.45 ENST00000435861.1
DTX2
deltex homolog 2 (Drosophila)
chr15_+_67813406 0.44 ENST00000342683.4
C15orf61
chromosome 15 open reading frame 61
chr17_-_79792909 0.44 ENST00000330261.4
ENST00000570394.1
PPP1R27
protein phosphatase 1, regulatory subunit 27
chr8_-_100905925 0.43 ENST00000518171.1
COX6C
cytochrome c oxidase subunit VIc
chr10_+_112257596 0.42 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr11_-_132813566 0.41 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr6_+_43968306 0.40 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr11_-_68611721 0.40 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr7_-_127671674 0.40 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr18_-_43678241 0.39 ENST00000593152.2
ENST00000589252.1
ENST00000590665.1
ENST00000398752.6
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr11_+_10472223 0.39 ENST00000396554.3
ENST00000524866.1
AMPD3
adenosine monophosphate deaminase 3
chr8_-_100905850 0.38 ENST00000520271.1
ENST00000522940.1
ENST00000523016.1
ENST00000517682.2
ENST00000297564.2
COX6C
cytochrome c oxidase subunit VIc
chr16_+_28874345 0.37 ENST00000566209.1
SH2B1
SH2B adaptor protein 1
chr17_-_65235916 0.36 ENST00000579861.1
HELZ
helicase with zinc finger
chr5_-_150473127 0.36 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr15_-_91475706 0.36 ENST00000561036.1
HDDC3
HD domain containing 3
chr1_+_161172143 0.36 ENST00000476409.2
NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr2_+_228190066 0.35 ENST00000436237.1
ENST00000443428.2
ENST00000418961.1
MFF
mitochondrial fission factor
chr13_-_50020554 0.34 ENST00000400396.1
AL136218.1
Sarcoma antigen NY-SAR-79; Uncharacterized protein
chr8_-_100905363 0.33 ENST00000524245.1
COX6C
cytochrome c oxidase subunit VIc
chr1_-_207119738 0.31 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr21_-_46330545 0.31 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr19_+_7011509 0.31 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr3_-_52312337 0.30 ENST00000469000.1
WDR82
WD repeat domain 82
chrX_+_48620147 0.30 ENST00000303227.6
GLOD5
glyoxalase domain containing 5
chr19_+_46850320 0.30 ENST00000391919.1
PPP5C
protein phosphatase 5, catalytic subunit
chr15_+_59730348 0.29 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr14_-_91282821 0.29 ENST00000553948.1
TTC7B
tetratricopeptide repeat domain 7B
chr1_+_169077133 0.29 ENST00000494797.1
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr14_+_51026844 0.28 ENST00000554886.1
ATL1
atlastin GTPase 1
chr14_-_103987679 0.28 ENST00000553610.1
CKB
creatine kinase, brain
chr7_-_68895857 0.27 ENST00000421513.1
RP11-3P22.2
RP11-3P22.2
chrX_-_154255143 0.27 ENST00000453950.1
ENST00000423959.1
F8
coagulation factor VIII, procoagulant component
chr16_-_4588391 0.26 ENST00000586728.1
CDIP1
cell death-inducing p53 target 1
chr8_-_131028782 0.26 ENST00000519020.1
FAM49B
family with sequence similarity 49, member B
chr3_+_102153859 0.26 ENST00000306176.1
ENST00000466937.1
ZPLD1
zona pellucida-like domain containing 1
chr3_-_179322436 0.25 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr11_+_118272328 0.25 ENST00000524422.1
ATP5L
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr1_+_29213678 0.25 ENST00000347529.3
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_-_23504176 0.25 ENST00000302291.4
LUZP1
leucine zipper protein 1
chr12_+_58176525 0.24 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr22_+_37959647 0.24 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr5_+_71403280 0.24 ENST00000511641.2
MAP1B
microtubule-associated protein 1B
chr19_-_7293942 0.24 ENST00000341500.5
ENST00000302850.5
INSR
insulin receptor
chr16_-_3767551 0.24 ENST00000246957.5
TRAP1
TNF receptor-associated protein 1
chr17_+_900342 0.24 ENST00000327158.4
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr11_+_65770227 0.24 ENST00000527348.1
BANF1
barrier to autointegration factor 1
chr11_+_67798114 0.23 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr3_+_10290596 0.23 ENST00000448281.2
TATDN2
TatD DNase domain containing 2
chr10_-_76995769 0.23 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr2_+_198365095 0.23 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr8_+_110346546 0.23 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2
enhancer of yellow 2 homolog (Drosophila)
chr8_+_145149930 0.23 ENST00000318911.4
CYC1
cytochrome c-1
chr12_-_120554534 0.23 ENST00000538903.1
ENST00000534951.1
RAB35
RAB35, member RAS oncogene family
chr17_-_1463095 0.23 ENST00000575895.1
ENST00000573056.1
PITPNA
phosphatidylinositol transfer protein, alpha
chr5_+_80529104 0.22 ENST00000254035.4
ENST00000511719.1
ENST00000437669.1
ENST00000424301.2
ENST00000505060.1
CKMT2
creatine kinase, mitochondrial 2 (sarcomeric)
chr16_-_3767506 0.22 ENST00000538171.1
TRAP1
TNF receptor-associated protein 1
chr18_-_56985776 0.22 ENST00000587244.1
CPLX4
complexin 4
chr17_+_46970134 0.22 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr19_+_38308119 0.22 ENST00000592103.1
CTD-2554C21.2
CTD-2554C21.2
chr6_-_13290684 0.22 ENST00000606393.1
RP1-257A7.5
RP1-257A7.5
chr17_+_79670386 0.22 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
MRPL12
SLC25A10
SLC25A10
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr18_-_12377001 0.22 ENST00000590811.1
AFG3L2
AFG3-like AAA ATPase 2
chr19_+_46850251 0.22 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr14_-_58893832 0.21 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr15_-_91475747 0.21 ENST00000330334.3
ENST00000559898.1
ENST00000394272.3
HDDC3
HD domain containing 3
chr20_+_30458431 0.21 ENST00000375938.4
ENST00000535842.1
ENST00000310998.4
ENST00000375921.2
TTLL9
tubulin tyrosine ligase-like family, member 9
chr2_+_238875597 0.21 ENST00000272930.4
ENST00000448502.1
ENST00000416292.1
ENST00000409633.1
ENST00000414443.1
ENST00000409953.1
ENST00000409332.1
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr1_+_16083123 0.21 ENST00000510393.1
ENST00000430076.1
FBLIM1
filamin binding LIM protein 1
chr4_+_76439649 0.20 ENST00000507557.1
THAP6
THAP domain containing 6
chr8_-_90769422 0.20 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1
RP11-37B2.1
chr12_-_57039739 0.20 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr16_+_691792 0.20 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr1_+_169077172 0.20 ENST00000499679.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_-_10028366 0.20 ENST00000429759.1
EMC3
ER membrane protein complex subunit 3
chr22_+_30821784 0.20 ENST00000407550.3
MTFP1
mitochondrial fission process 1
chr4_-_140216948 0.19 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr6_+_30749649 0.19 ENST00000422944.1
HCG20
HLA complex group 20 (non-protein coding)
chr20_+_31755934 0.19 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr1_+_155179012 0.19 ENST00000609421.1
MTX1
metaxin 1
chr15_+_78441663 0.19 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr1_-_33502528 0.19 ENST00000354858.6
AK2
adenylate kinase 2
chr11_+_3968573 0.19 ENST00000532990.1
STIM1
stromal interaction molecule 1
chr8_-_102275131 0.19 ENST00000523121.1
KB-1410C5.2
KB-1410C5.2
chr2_+_172950227 0.19 ENST00000341900.6
DLX1
distal-less homeobox 1
chr9_-_130889990 0.19 ENST00000449878.1
PTGES2
prostaglandin E synthase 2
chr19_+_57742369 0.19 ENST00000415300.2
ENST00000448930.1
AURKC
aurora kinase C
chr15_+_67458861 0.19 ENST00000558428.1
ENST00000558827.1
SMAD3
SMAD family member 3
chr1_-_17380630 0.18 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr13_-_111214015 0.18 ENST00000267328.3
RAB20
RAB20, member RAS oncogene family
chr3_+_184037466 0.18 ENST00000441154.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr19_-_18314799 0.18 ENST00000481914.2
RAB3A
RAB3A, member RAS oncogene family
chr16_+_777118 0.18 ENST00000562141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr9_+_134001455 0.18 ENST00000531584.1
NUP214
nucleoporin 214kDa
chr14_-_75536182 0.18 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr11_+_57480046 0.18 ENST00000378312.4
ENST00000278422.4
TMX2
thioredoxin-related transmembrane protein 2
chr15_-_41694640 0.18 ENST00000558719.1
ENST00000260361.4
ENST00000560978.1
NDUFAF1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
chr2_-_176046391 0.17 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr1_+_161195835 0.17 ENST00000545897.1
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr3_+_184038073 0.17 ENST00000428387.1
ENST00000434061.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_+_165600436 0.17 ENST00000367888.4
ENST00000367885.1
ENST00000367884.2
MGST3
microsomal glutathione S-transferase 3
chr3_+_128968437 0.17 ENST00000314797.6
COPG1
coatomer protein complex, subunit gamma 1
chr2_+_145425573 0.17 ENST00000600064.1
ENST00000597670.1
ENST00000414256.1
ENST00000599187.1
ENST00000451774.1
ENST00000599072.1
ENST00000596589.1
ENST00000597893.1
TEX41
testis expressed 41 (non-protein coding)
chr11_-_132812987 0.17 ENST00000541867.1
OPCML
opioid binding protein/cell adhesion molecule-like
chr7_+_44836276 0.17 ENST00000451562.1
ENST00000468812.1
ENST00000489459.1
ENST00000355968.6
PPIA
peptidylprolyl isomerase A (cyclophilin A)
chr7_-_139876734 0.17 ENST00000006967.5
JHDM1D
lysine (K)-specific demethylase 7A
chr19_+_35521572 0.17 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr22_+_30792980 0.17 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr19_-_55574538 0.17 ENST00000415061.3
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr2_-_86422095 0.17 ENST00000254636.5
IMMT
inner membrane protein, mitochondrial
chr1_-_33502441 0.17 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
AK2
adenylate kinase 2
chr12_+_109915422 0.17 ENST00000280774.5
ENST00000536398.1
ENST00000539599.1
ENST00000342494.3
ENST00000340074.5
ENST00000540230.1
ENST00000537063.1
UBE3B
ubiquitin protein ligase E3B
chr9_+_112852477 0.17 ENST00000480388.1
AKAP2
A kinase (PRKA) anchor protein 2
chr8_+_119294456 0.17 ENST00000366457.2
AC023590.1
Uncharacterized protein
chrX_-_154033661 0.16 ENST00000393531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr1_-_159825137 0.16 ENST00000368102.1
C1orf204
chromosome 1 open reading frame 204
chr13_+_22245522 0.16 ENST00000382353.5
FGF9
fibroblast growth factor 9
chr12_-_30907822 0.16 ENST00000540436.1
CAPRIN2
caprin family member 2
chr3_+_179065474 0.16 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr8_+_86376081 0.16 ENST00000285379.5
CA2
carbonic anhydrase II
chr15_-_42783303 0.16 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr16_-_74734672 0.15 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr10_-_123734683 0.15 ENST00000369017.5
ENST00000369023.3
NSMCE4A
non-SMC element 4 homolog A (S. cerevisiae)
chr1_+_161195781 0.15 ENST00000367988.3
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr2_-_31030277 0.15 ENST00000534090.2
ENST00000295055.8
CAPN13
calpain 13
chr17_-_46799872 0.15 ENST00000290294.3
PRAC1
prostate cancer susceptibility candidate 1
chr17_-_49198216 0.15 ENST00000262013.7
ENST00000357122.4
SPAG9
sperm associated antigen 9
chr4_+_2470664 0.15 ENST00000314289.8
ENST00000541204.1
ENST00000502316.1
ENST00000507247.1
ENST00000509258.1
ENST00000511859.1
RNF4
ring finger protein 4
chrX_-_46187069 0.15 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr16_+_85833274 0.15 ENST00000568794.1
ENST00000253452.2
ENST00000562336.1
ENST00000561569.1
ENST00000566405.1
COX4I1
cytochrome c oxidase subunit IV isoform 1
chr2_-_220119280 0.15 ENST00000392088.2
TUBA4A
tubulin, alpha 4a
chr8_+_101349823 0.15 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr15_+_45021183 0.15 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr5_-_150537279 0.15 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
ANXA6
annexin A6
chr11_-_34379546 0.15 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr14_-_21492113 0.15 ENST00000554094.1
NDRG2
NDRG family member 2
chr1_-_154164534 0.15 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chrX_-_46618490 0.14 ENST00000328306.4
SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr20_+_58179582 0.14 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr4_-_76957214 0.14 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr2_+_145425534 0.14 ENST00000432608.1
ENST00000597655.1
ENST00000598659.1
ENST00000600679.1
ENST00000601277.1
ENST00000451027.1
ENST00000445791.1
ENST00000596540.1
ENST00000596230.1
ENST00000594471.1
ENST00000598248.1
ENST00000597469.1
ENST00000431734.1
ENST00000595686.1
TEX41
testis expressed 41 (non-protein coding)
chr4_-_108204904 0.14 ENST00000510463.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr9_-_130637244 0.14 ENST00000373156.1
AK1
adenylate kinase 1
chr7_+_129007964 0.14 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr3_-_16306432 0.14 ENST00000383775.4
ENST00000488423.1
DPH3
diphthamide biosynthesis 3
chr14_-_24729251 0.14 ENST00000559136.1
TGM1
transglutaminase 1
chr16_+_2588012 0.13 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr1_+_169075554 0.13 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr17_+_55334364 0.13 ENST00000322684.3
ENST00000579590.1
MSI2
musashi RNA-binding protein 2
chr3_+_10068095 0.13 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr11_+_77899842 0.13 ENST00000530267.1
USP35
ubiquitin specific peptidase 35
chr16_-_74734742 0.13 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr5_+_177540444 0.13 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr5_+_34757309 0.13 ENST00000397449.1
RAI14
retinoic acid induced 14
chr2_-_128432639 0.13 ENST00000545738.2
ENST00000355119.4
ENST00000409808.2
LIMS2
LIM and senescent cell antigen-like domains 2
chr3_+_16306691 0.13 ENST00000285083.5
ENST00000605932.1
ENST00000435829.2
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr19_+_57742431 0.13 ENST00000302804.7
AURKC
aurora kinase C
chrX_-_154689596 0.13 ENST00000369444.2
H2AFB3
H2A histone family, member B3
chr1_+_44444865 0.13 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr12_+_51632666 0.13 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr17_-_76778339 0.13 ENST00000591455.1
ENST00000446868.3
ENST00000361101.4
ENST00000589296.1
CYTH1
cytohesin 1
chr14_-_105262055 0.13 ENST00000349310.3
AKT1
v-akt murine thymoma viral oncogene homolog 1
chr5_+_38445641 0.13 ENST00000397210.3
ENST00000506135.1
ENST00000508131.1
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr14_-_105262016 0.12 ENST00000407796.2
AKT1
v-akt murine thymoma viral oncogene homolog 1
chr10_+_60028818 0.12 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr15_-_83621435 0.12 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2
homer homolog 2 (Drosophila)
chr16_+_718147 0.12 ENST00000561929.1
RHOT2
ras homolog family member T2
chr11_+_111957497 0.12 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr10_+_105156364 0.12 ENST00000369797.3
PDCD11
programmed cell death 11
chr3_-_167452262 0.12 ENST00000487947.2
PDCD10
programmed cell death 10
chr15_+_36887069 0.12 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr16_+_2587965 0.12 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr6_+_107349392 0.12 ENST00000443043.1
ENST00000405204.2
ENST00000311381.5
C6orf203
chromosome 6 open reading frame 203
chr17_-_67323385 0.12 ENST00000588665.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr1_+_201924619 0.12 ENST00000367287.4
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr10_+_81107271 0.12 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr22_+_30821732 0.12 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr11_+_77899920 0.12 ENST00000528910.1
ENST00000529308.1
USP35
ubiquitin specific peptidase 35
chr3_-_49377499 0.12 ENST00000265560.4
USP4
ubiquitin specific peptidase 4 (proto-oncogene)
chr19_+_38307999 0.12 ENST00000589653.1
ENST00000590433.1
CTD-2554C21.2
CTD-2554C21.2
chrX_-_154033686 0.12 ENST00000453245.1
ENST00000428488.1
ENST00000369531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr15_+_43885799 0.11 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr3_+_113465866 0.11 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr8_-_125869733 0.11 ENST00000533496.1
RP11-1082L8.3
RP11-1082L8.3
chr5_+_73109339 0.11 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28

Network of associatons between targets according to the STRING database.

First level regulatory network of ESRRB_ESRRG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.0 GO:0019236 response to pheromone(GO:0019236)
0.1 0.5 GO:0009386 translational attenuation(GO:0009386)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.6 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.2 GO:0021503 neural fold bending(GO:0021503)
0.1 0.2 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.4 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.2 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.2 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 1.9 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.1 0.3 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 1.9 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.2 GO:0042938 positive regulation of cellular pH reduction(GO:0032849) dipeptide transport(GO:0042938)
0.1 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 1.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.6 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:0006218 uridine catabolic process(GO:0006218)
0.0 1.1 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.0 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.0 0.2 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.1 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.1 GO:0050975 sensory perception of touch(GO:0050975) maintenance of synapse structure(GO:0099558) presynaptic active zone organization(GO:1990709)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.2 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 0.1 GO:0048864 stem cell development(GO:0048864)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.0 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0021644 vagus nerve morphogenesis(GO:0021644)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.6 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.4 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.3 GO:0035404 histone-serine phosphorylation(GO:0035404) mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.3 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.0 GO:0060262 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 0.1 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.0 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.2 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.3 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.0 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.0 GO:1904875 regulation of DNA ligase activity(GO:1904875)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.3 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.0 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.0 GO:0044753 amphisome(GO:0044753)
0.0 0.0 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.4 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.4 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 1.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.2 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.2 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.2 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.5 GO:0015266 protein channel activity(GO:0015266)
0.0 0.3 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.9 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.2 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 ST GAQ PATHWAY G alpha q Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling