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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ETV4_ETS2

Z-value: 1.20

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Transcription factors associated with ETV4_ETS2

Gene Symbol Gene ID Gene Info
ETV4
ENSG00000175832.8 ETS variant transcription factor 4
ETS2
ENSG00000157557.7 ETS proto-oncogene 2, transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETV4hg19_v2_chr17_-_41623691_416237150.681.4e-01Click!
ETS2hg19_v2_chr21_+_40181520_40181560-0.364.8e-01Click!

Activity profile of ETV4_ETS2 motif

Sorted Z-values of ETV4_ETS2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_47324008 1.12 ENST00000425853.1
KIF9
kinesin family member 9
chr16_-_67260901 1.05 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29
AC040160.1
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr1_+_153330322 0.92 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr11_-_64885111 0.87 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr3_-_47324242 0.87 ENST00000456548.1
ENST00000432493.1
ENST00000335044.2
ENST00000444589.2
KIF9
kinesin family member 9
chr2_+_74212073 0.87 ENST00000441217.1
AC073046.25
AC073046.25
chr15_-_80263506 0.87 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr6_+_31515337 0.84 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr2_+_228678550 0.83 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr11_+_313503 0.77 ENST00000528780.1
ENST00000328221.5
IFITM1
interferon induced transmembrane protein 1
chr9_-_139268068 0.69 ENST00000371734.3
ENST00000371732.5
ENST00000315908.7
CARD9
caspase recruitment domain family, member 9
chr17_+_38171681 0.67 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr1_-_209792111 0.67 ENST00000455193.1
LAMB3
laminin, beta 3
chr15_-_71184724 0.67 ENST00000560604.1
THAP10
THAP domain containing 10
chr17_+_6918093 0.65 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr17_+_6918064 0.64 ENST00000546760.1
ENST00000552402.1
C17orf49
chromosome 17 open reading frame 49
chr5_+_159895275 0.63 ENST00000517927.1
MIR146A
microRNA 146a
chr17_+_4843594 0.63 ENST00000570328.1
RNF167
ring finger protein 167
chr1_+_156698708 0.59 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr3_-_142720267 0.58 ENST00000597953.1
RP11-91G21.1
RP11-91G21.1
chr17_-_48277552 0.58 ENST00000507689.1
COL1A1
collagen, type I, alpha 1
chr19_-_10230562 0.57 ENST00000587146.1
ENST00000588709.1
ENST00000253108.4
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr20_-_48532046 0.55 ENST00000543716.1
SPATA2
spermatogenesis associated 2
chr2_+_138721850 0.54 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr14_-_45431091 0.54 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr22_+_30752963 0.54 ENST00000445005.1
ENST00000430839.1
CCDC157
coiled-coil domain containing 157
chr20_-_48532019 0.54 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr17_+_38171614 0.54 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr17_-_6917755 0.53 ENST00000593646.1
AC040977.1
Uncharacterized protein
chr5_-_176730676 0.53 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr15_+_75074410 0.52 ENST00000439220.2
CSK
c-src tyrosine kinase
chr11_-_62389577 0.50 ENST00000534715.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr2_+_234160340 0.50 ENST00000417017.1
ENST00000392020.4
ENST00000392018.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr17_+_45908974 0.48 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr22_+_30752606 0.48 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
CCDC157
coiled-coil domain containing 157
chr17_+_6918354 0.46 ENST00000552775.1
C17orf49
chromosome 17 open reading frame 49
chr3_-_51975942 0.46 ENST00000232888.6
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr1_+_152881014 0.46 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr3_-_47324060 0.45 ENST00000452770.2
KIF9
kinesin family member 9
chr6_+_126240442 0.45 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr12_+_7053172 0.44 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr19_+_15218180 0.44 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr2_+_37458904 0.44 ENST00000416653.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr4_+_110736659 0.44 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chr17_+_4843352 0.43 ENST00000573404.1
ENST00000576452.1
RNF167
ring finger protein 167
chr15_-_85197501 0.43 ENST00000434634.2
WDR73
WD repeat domain 73
chr3_+_47324424 0.42 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18
kelch-like family member 18
chr16_-_66968265 0.42 ENST00000567511.1
ENST00000422424.2
FAM96B
family with sequence similarity 96, member B
chr3_-_47324079 0.42 ENST00000352910.4
KIF9
kinesin family member 9
chr11_-_9336117 0.42 ENST00000527813.1
ENST00000533723.1
TMEM41B
transmembrane protein 41B
chr15_-_55488817 0.42 ENST00000569386.1
RSL24D1
ribosomal L24 domain containing 1
chrX_-_48937684 0.41 ENST00000465382.1
ENST00000423215.2
WDR45
WD repeat domain 45
chr11_+_46722368 0.41 ENST00000311764.2
ZNF408
zinc finger protein 408
chr1_-_209957882 0.41 ENST00000294811.1
C1orf74
chromosome 1 open reading frame 74
chr14_+_75988851 0.41 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr3_+_52321827 0.40 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
GLYCTK
glycerate kinase
chr15_+_90744533 0.40 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr7_-_5569588 0.40 ENST00000417101.1
ACTB
actin, beta
chr11_-_47270341 0.40 ENST00000529444.1
ENST00000530453.1
ENST00000537863.1
ENST00000529788.1
ENST00000444355.2
ENST00000527256.1
ENST00000529663.1
ENST00000256997.3
ACP2
acid phosphatase 2, lysosomal
chr1_+_156698743 0.39 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr2_+_234160217 0.39 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr6_-_31620455 0.39 ENST00000437771.1
ENST00000404765.2
ENST00000375964.6
ENST00000211379.5
BAG6
BCL2-associated athanogene 6
chr16_-_2097787 0.39 ENST00000566380.1
ENST00000219066.1
NTHL1
nth endonuclease III-like 1 (E. coli)
chr6_+_31620191 0.38 ENST00000375918.2
ENST00000375920.4
APOM
apolipoprotein M
chr11_+_2421718 0.38 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4
tumor suppressing subtransferable candidate 4
chr20_+_34287364 0.37 ENST00000374072.1
ENST00000397416.1
ENST00000336695.4
ROMO1
reactive oxygen species modulator 1
chr14_+_24630465 0.37 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9
interferon regulatory factor 9
chr17_+_45331184 0.37 ENST00000559488.1
ENST00000571680.1
ENST00000435993.2
ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr22_+_37678505 0.37 ENST00000402997.1
ENST00000405206.3
CYTH4
cytohesin 4
chr15_+_75074385 0.36 ENST00000220003.9
CSK
c-src tyrosine kinase
chr11_-_46722117 0.36 ENST00000311956.4
ARHGAP1
Rho GTPase activating protein 1
chr15_+_75074915 0.35 ENST00000567123.1
ENST00000569462.1
CSK
c-src tyrosine kinase
chr11_+_63655987 0.35 ENST00000509502.2
ENST00000512060.1
MARK2
MAP/microtubule affinity-regulating kinase 2
chr19_-_11039261 0.35 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
YIPF2
Yip1 domain family, member 2
chr17_-_4843316 0.34 ENST00000544061.2
SLC25A11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr1_-_151254362 0.34 ENST00000447795.2
RP11-126K1.2
Uncharacterized protein
chr6_-_34524049 0.34 ENST00000374037.3
SPDEF
SAM pointed domain containing ETS transcription factor
chr6_-_31620403 0.34 ENST00000451898.1
ENST00000439687.2
ENST00000362049.6
ENST00000424480.1
BAG6
BCL2-associated athanogene 6
chr5_+_93954358 0.34 ENST00000504099.1
ANKRD32
ankyrin repeat domain 32
chr12_-_94673956 0.33 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr6_-_11382478 0.33 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr17_+_18218587 0.33 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr16_-_57513657 0.32 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr1_-_156698591 0.32 ENST00000368219.1
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr9_-_138987115 0.32 ENST00000277554.2
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr3_-_178865747 0.32 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr17_-_7760779 0.32 ENST00000335155.5
ENST00000575071.1
LSMD1
LSM domain containing 1
chr17_+_4843413 0.32 ENST00000572430.1
ENST00000262482.6
RNF167
ring finger protein 167
chr20_-_2451395 0.32 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr12_+_7052974 0.32 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr4_+_8201091 0.32 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr19_-_11039188 0.32 ENST00000588347.1
YIPF2
Yip1 domain family, member 2
chr20_+_3767547 0.31 ENST00000344256.6
ENST00000379598.5
CDC25B
cell division cycle 25B
chr1_-_894620 0.31 ENST00000327044.6
NOC2L
nucleolar complex associated 2 homolog (S. cerevisiae)
chr19_-_51289436 0.31 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chr11_-_102401469 0.31 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr1_-_114429997 0.31 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr1_-_109618566 0.31 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr17_+_7942424 0.31 ENST00000573359.1
ALOX15B
arachidonate 15-lipoxygenase, type B
chr12_+_7053228 0.31 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr13_-_33760216 0.31 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr16_+_4666475 0.30 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr17_+_67590125 0.30 ENST00000591334.1
AC003051.1
AC003051.1
chr16_+_2732476 0.30 ENST00000301738.4
ENST00000564195.1
KCTD5
potassium channel tetramerization domain containing 5
chr2_-_242556900 0.30 ENST00000402545.1
ENST00000402136.1
THAP4
THAP domain containing 4
chr8_-_104427313 0.30 ENST00000297578.4
SLC25A32
solute carrier family 25 (mitochondrial folate carrier), member 32
chr17_+_4843679 0.29 ENST00000576229.1
RNF167
ring finger protein 167
chr17_+_26662679 0.29 ENST00000578158.1
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr8_-_38034192 0.29 ENST00000520755.1
LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_-_79269067 0.29 ENST00000288439.5
ENST00000374759.3
SLC38A10
solute carrier family 38, member 10
chr1_-_156698181 0.29 ENST00000313146.6
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr17_+_48351785 0.28 ENST00000507382.1
TMEM92
transmembrane protein 92
chr14_-_37051798 0.28 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr16_-_66968055 0.28 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chr2_+_37571717 0.28 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr11_+_65408273 0.28 ENST00000394227.3
SIPA1
signal-induced proliferation-associated 1
chr17_-_39093672 0.28 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr1_+_16767167 0.28 ENST00000337132.5
NECAP2
NECAP endocytosis associated 2
chr14_+_23341513 0.28 ENST00000546834.1
LRP10
low density lipoprotein receptor-related protein 10
chr5_+_176730769 0.28 ENST00000303204.4
ENST00000503216.1
PRELID1
PRELI domain containing 1
chr17_+_7942335 0.28 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
ALOX15B
arachidonate 15-lipoxygenase, type B
chr2_+_37458928 0.28 ENST00000439218.1
ENST00000432075.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr14_+_65170820 0.28 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_-_55515400 0.27 ENST00000497027.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr17_-_62493131 0.27 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr16_-_28503080 0.27 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr20_+_48884002 0.27 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr14_-_103989033 0.27 ENST00000553878.1
ENST00000557530.1
CKB
creatine kinase, brain
chr2_+_220462560 0.27 ENST00000456909.1
ENST00000295641.10
STK11IP
serine/threonine kinase 11 interacting protein
chr5_+_66300464 0.27 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr11_+_844406 0.27 ENST00000397404.1
TSPAN4
tetraspanin 4
chr18_+_3261883 0.27 ENST00000237500.5
MYL12B
myosin, light chain 12B, regulatory
chr22_+_38004723 0.27 ENST00000381756.5
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr6_-_41908428 0.27 ENST00000505064.1
CCND3
cyclin D3
chr19_+_40854559 0.27 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
PLD3
phospholipase D family, member 3
chr4_-_103266626 0.27 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr6_-_33385854 0.27 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr5_-_140070897 0.27 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
HARS
histidyl-tRNA synthetase
chr11_+_65407331 0.27 ENST00000527525.1
SIPA1
signal-induced proliferation-associated 1
chr2_+_239335636 0.26 ENST00000409297.1
ASB1
ankyrin repeat and SOCS box containing 1
chr19_-_10341948 0.26 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr14_+_93389425 0.26 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr6_+_26156551 0.26 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr17_-_76123101 0.26 ENST00000392467.3
TMC6
transmembrane channel-like 6
chr19_-_49243845 0.26 ENST00000222145.4
RASIP1
Ras interacting protein 1
chr5_+_61874562 0.26 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr7_-_100888313 0.26 ENST00000442303.1
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr6_-_43595039 0.26 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr20_+_34287194 0.26 ENST00000374078.1
ENST00000374077.3
ROMO1
reactive oxygen species modulator 1
chr3_-_170626376 0.26 ENST00000487522.1
ENST00000474417.1
EIF5A2
eukaryotic translation initiation factor 5A2
chr11_+_93754513 0.26 ENST00000315765.9
HEPHL1
hephaestin-like 1
chr18_-_47813940 0.25 ENST00000586837.1
ENST00000412036.2
ENST00000589940.1
CXXC1
CXXC finger protein 1
chr1_-_183560011 0.25 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr9_-_130617029 0.25 ENST00000373203.4
ENG
endoglin
chr12_+_96588143 0.25 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr19_+_56186606 0.25 ENST00000085079.7
EPN1
epsin 1
chr9_-_91793675 0.25 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr11_+_65337901 0.25 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
SSSCA1
Sjogren syndrome/scleroderma autoantigen 1
chr6_-_33290580 0.25 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
DAXX
death-domain associated protein
chr17_+_27895609 0.25 ENST00000581411.2
ENST00000301057.7
TP53I13
tumor protein p53 inducible protein 13
chr19_-_12792585 0.25 ENST00000351660.5
DHPS
deoxyhypusine synthase
chr5_-_150466692 0.25 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chrX_+_115567767 0.25 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr5_+_149380256 0.24 ENST00000502717.1
HMGXB3
HMG box domain containing 3
chr19_+_56186557 0.24 ENST00000270460.6
EPN1
epsin 1
chr19_-_16653325 0.24 ENST00000546361.2
CHERP
calcium homeostasis endoplasmic reticulum protein
chr6_+_30524663 0.24 ENST00000376560.3
PRR3
proline rich 3
chr8_+_95565947 0.24 ENST00000523011.1
RP11-267M23.4
RP11-267M23.4
chr16_-_30204987 0.24 ENST00000569282.1
ENST00000567436.1
BOLA2B
bolA family member 2B
chr17_+_1944790 0.24 ENST00000575162.1
DPH1
diphthamide biosynthesis 1
chr16_-_28503357 0.24 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr5_+_141303461 0.24 ENST00000508751.1
KIAA0141
KIAA0141
chr16_+_3185125 0.24 ENST00000576416.1
ZNF213
zinc finger protein 213
chr6_-_112575758 0.24 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr10_-_99161033 0.24 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr6_-_42110342 0.24 ENST00000356542.5
C6orf132
chromosome 6 open reading frame 132
chr2_-_96811170 0.24 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr17_-_76356148 0.24 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chr4_+_76439095 0.24 ENST00000506261.1
THAP6
THAP domain containing 6
chr20_+_55967129 0.24 ENST00000371219.2
RBM38
RNA binding motif protein 38
chr5_-_40835303 0.24 ENST00000509877.1
ENST00000508493.1
ENST00000274242.5
RPL37
ribosomal protein L37
chr1_+_1260147 0.24 ENST00000343938.4
GLTPD1
glycolipid transfer protein domain containing 1
chr17_+_80009330 0.24 ENST00000580716.1
ENST00000583961.1
GPS1
G protein pathway suppressor 1
chr7_-_130080681 0.23 ENST00000469826.1
CEP41
centrosomal protein 41kDa
chr3_-_50340996 0.23 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr16_+_31085714 0.23 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646
zinc finger protein 646
chr19_-_10230540 0.23 ENST00000589454.1
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr16_+_3184924 0.23 ENST00000574902.1
ENST00000396878.3
ZNF213
zinc finger protein 213
chr22_+_38004832 0.23 ENST00000405147.3
ENST00000429218.1
ENST00000325180.8
ENST00000337437.4
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr6_-_31620149 0.23 ENST00000435080.1
ENST00000375976.4
ENST00000441054.1
BAG6
BCL2-associated athanogene 6
chr17_+_4843654 0.23 ENST00000575111.1
RNF167
ring finger protein 167
chr5_-_150467221 0.23 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr17_+_74723031 0.23 ENST00000586200.1
METTL23
methyltransferase like 23
chr10_-_98031155 0.23 ENST00000495266.1
BLNK
B-cell linker
chr3_+_109128837 0.23 ENST00000497996.1
RP11-702L6.4
RP11-702L6.4
chr1_+_114522049 0.22 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr5_-_137090028 0.22 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr19_-_16653226 0.22 ENST00000198939.6
CHERP
calcium homeostasis endoplasmic reticulum protein
chr16_-_31519691 0.22 ENST00000567994.1
ENST00000430477.2
ENST00000570164.1
ENST00000327237.2
C16orf58
chromosome 16 open reading frame 58
chr19_+_11546440 0.22 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV4_ETS2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 0.9 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.1 GO:0036343 psychomotor behavior(GO:0036343)
0.2 0.8 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 1.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 0.5 GO:0042631 cellular response to water deprivation(GO:0042631)
0.2 0.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 0.5 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.9 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.6 GO:0044691 tooth eruption(GO:0044691)
0.1 0.4 GO:0001300 chronological cell aging(GO:0001300)
0.1 1.4 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.4 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.8 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.6 GO:0046203 spermidine catabolic process(GO:0046203)
0.1 0.5 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 1.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.5 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.4 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.5 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.5 GO:0060481 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.1 0.3 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.3 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.2 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 0.8 GO:0051715 cytolysis in other organism(GO:0051715)
0.1 0.6 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 3.1 GO:0071801 regulation of podosome assembly(GO:0071801)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.2 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.3 GO:0036517 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.1 0.2 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.6 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.1 0.7 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.2 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.3 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 0.3 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.2 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 0.2 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.5 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.3 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.2 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.1 0.2 GO:0016598 protein arginylation(GO:0016598)
0.0 0.2 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.2 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.2 GO:0044010 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0 0.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.2 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.9 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.7 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.2 GO:0033590 response to cobalamin(GO:0033590)
0.0 0.2 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.0 GO:1990564 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.3 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.3 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0031346 positive regulation of cell projection organization(GO:0031346)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.5 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.9 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0014744 positive regulation of muscle adaptation(GO:0014744)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216) DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:1902362 melanocyte proliferation(GO:0097325) melanocyte apoptotic process(GO:1902362)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) regulation of single strand break repair(GO:1903516) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.0 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.3 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.0 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0060058 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.5 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:2000397 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0035697 CD8-positive, alpha-beta T cell extravasation(GO:0035697) CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of T cell extravasation(GO:2000407) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0045073 chemokine biosynthetic process(GO:0042033) regulation of chemokine biosynthetic process(GO:0045073)
0.0 0.5 GO:0044804 nucleophagy(GO:0044804)
0.0 0.0 GO:0072708 response to sorbitol(GO:0072708)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:1903147 negative regulation of mitophagy(GO:1903147)
0.0 0.1 GO:1990029 pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.0 0.2 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.7 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.3 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.0 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.0 GO:0046070 dGTP metabolic process(GO:0046070)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.0 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:0033320 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0060971 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593) negative regulation of lamellipodium organization(GO:1902744)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.1 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.0 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0008355 olfactory learning(GO:0008355)
0.0 0.0 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.4 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.0 GO:1990709 presynaptic active zone organization(GO:1990709)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:1903362 regulation of cellular protein catabolic process(GO:1903362)
0.0 0.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.1 GO:1904796 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) regulation of core promoter binding(GO:1904796)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.1 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.0 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:1903301 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.7 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.1 GO:1904338 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.0 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.0 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.1 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0061141 lung ciliated cell differentiation(GO:0061141)
0.0 0.0 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.0 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.0 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.0 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330) positive regulation of cell cycle arrest(GO:0071158)
0.0 0.0 GO:1902214 regulation of interleukin-4-mediated signaling pathway(GO:1902214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.4 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.8 GO:0071817 MMXD complex(GO:0071817)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.1 0.6 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 1.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.3 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.5 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.1 GO:0000785 chromatin(GO:0000785)
0.1 1.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0042565 nuclear RNA export factor complex(GO:0042272) RNA nuclear export complex(GO:0042565)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 3.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.2 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.4 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.0 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.0 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0005874 microtubule(GO:0005874)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 0.6 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.2 0.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 1.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.5 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.6 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.3 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.2 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.3 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 0.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.4 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.2 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.1 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.4 GO:0005534 galactose binding(GO:0005534)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 1.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.2 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.1 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.2 GO:0004057 arginyltransferase activity(GO:0004057)
0.1 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.3 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 1.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.9 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 2.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.0 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0015227 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.0 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.0 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.0 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.0 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.0 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.0 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.6 ST GAQ PATHWAY G alpha q Pathway
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 1.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME KINESINS Genes involved in Kinesins
0.1 0.3 REACTOME MITOTIC G2 G2 M PHASES Genes involved in Mitotic G2-G2/M phases
0.0 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 1.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway