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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ETV6

Z-value: 1.20

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Transcription factors associated with ETV6

Gene Symbol Gene ID Gene Info
ETV6
ENSG00000139083.6 ETS variant transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETV6hg19_v2_chr12_+_11802753_118028340.295.7e-01Click!

Activity profile of ETV6 motif

Sorted Z-values of ETV6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153066998 1.71 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr15_-_80263506 1.14 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr1_-_153044083 1.10 ENST00000341611.2
SPRR2B
small proline-rich protein 2B
chr17_+_77020325 1.06 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_77020224 1.02 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr5_-_150473127 0.81 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr6_+_26156551 0.65 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr17_+_77020146 0.55 ENST00000579760.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr16_+_67226019 0.53 ENST00000379378.3
E2F4
E2F transcription factor 4, p107/p130-binding
chr1_-_54518865 0.51 ENST00000371337.3
TMEM59
transmembrane protein 59
chr11_-_67205538 0.50 ENST00000326294.3
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr12_+_64846129 0.48 ENST00000540417.1
ENST00000539810.1
TBK1
TANK-binding kinase 1
chr20_+_2821366 0.46 ENST00000453689.1
ENST00000417508.1
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr17_+_45908974 0.45 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr6_-_11382478 0.44 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr2_+_239335636 0.42 ENST00000409297.1
ASB1
ankyrin repeat and SOCS box containing 1
chr12_-_58329819 0.41 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr22_+_38004723 0.40 ENST00000381756.5
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr19_+_52693259 0.40 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr1_-_2323140 0.40 ENST00000378531.3
ENST00000378529.3
MORN1
MORN repeat containing 1
chr1_-_246729544 0.39 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr6_-_31620095 0.39 ENST00000424176.1
ENST00000456622.1
BAG6
BCL2-associated athanogene 6
chr12_+_64845864 0.38 ENST00000538890.1
TBK1
TANK-binding kinase 1
chr3_-_16555150 0.36 ENST00000334133.4
RFTN1
raftlin, lipid raft linker 1
chr3_-_52739670 0.36 ENST00000497953.1
GLT8D1
glycosyltransferase 8 domain containing 1
chr19_-_11669960 0.36 ENST00000589171.1
ENST00000590700.1
ENST00000586683.1
ENST00000593077.1
ENST00000252445.3
ELOF1
elongation factor 1 homolog (S. cerevisiae)
chr5_+_159656437 0.35 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr1_-_43855444 0.35 ENST00000372455.4
MED8
mediator complex subunit 8
chr19_-_9929484 0.35 ENST00000586651.1
ENST00000586073.1
FBXL12
F-box and leucine-rich repeat protein 12
chr17_-_61904420 0.34 ENST00000580272.1
FTSJ3
FtsJ homolog 3 (E. coli)
chr19_-_54618650 0.34 ENST00000391757.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr6_-_31620403 0.34 ENST00000451898.1
ENST00000439687.2
ENST00000362049.6
ENST00000424480.1
BAG6
BCL2-associated athanogene 6
chr1_+_150266256 0.34 ENST00000309092.7
ENST00000369084.5
MRPS21
mitochondrial ribosomal protein S21
chr14_+_100842735 0.34 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WDR25
WD repeat domain 25
chr16_+_69373471 0.33 ENST00000569637.2
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr2_+_38152462 0.33 ENST00000354545.2
RMDN2
regulator of microtubule dynamics 2
chr20_+_58713514 0.32 ENST00000432910.1
RP5-1043L13.1
RP5-1043L13.1
chr14_-_24711865 0.31 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr22_+_38004832 0.31 ENST00000405147.3
ENST00000429218.1
ENST00000325180.8
ENST00000337437.4
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr10_+_44101850 0.31 ENST00000361807.3
ENST00000374437.2
ENST00000430885.1
ENST00000374435.3
ZNF485
zinc finger protein 485
chr9_-_100684769 0.30 ENST00000455506.1
ENST00000375117.4
C9orf156
chromosome 9 open reading frame 156
chr19_-_59066452 0.30 ENST00000312547.2
CHMP2A
charged multivesicular body protein 2A
chr22_+_38005033 0.30 ENST00000447515.1
ENST00000406772.1
ENST00000431745.1
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr6_-_31620455 0.30 ENST00000437771.1
ENST00000404765.2
ENST00000375964.6
ENST00000211379.5
BAG6
BCL2-associated athanogene 6
chr6_-_43496605 0.29 ENST00000455285.2
XPO5
exportin 5
chr19_+_49497121 0.29 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr20_-_34542548 0.29 ENST00000305978.2
SCAND1
SCAN domain containing 1
chr1_+_15736359 0.29 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr19_+_49496782 0.29 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr19_-_9938480 0.28 ENST00000585379.1
FBXL12
F-box and leucine-rich repeat protein 12
chr19_-_10230562 0.28 ENST00000587146.1
ENST00000588709.1
ENST00000253108.4
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr7_+_155090271 0.28 ENST00000476756.1
INSIG1
insulin induced gene 1
chr12_-_123459105 0.28 ENST00000543935.1
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr6_-_31620149 0.27 ENST00000435080.1
ENST00000375976.4
ENST00000441054.1
BAG6
BCL2-associated athanogene 6
chr16_-_420338 0.27 ENST00000450882.1
ENST00000441883.1
ENST00000447696.1
ENST00000389675.2
MRPL28
mitochondrial ribosomal protein L28
chr16_+_30406423 0.27 ENST00000524644.1
ZNF48
zinc finger protein 48
chr6_-_31619892 0.26 ENST00000454165.1
ENST00000428326.1
ENST00000452994.1
BAG6
BCL2-associated athanogene 6
chr7_-_91509972 0.26 ENST00000425936.1
MTERF
mitochondrial transcription termination factor
chr16_+_69373323 0.26 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr14_-_24711470 0.25 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr2_-_27632390 0.25 ENST00000350803.4
ENST00000344034.4
PPM1G
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr9_+_97021572 0.25 ENST00000395395.2
ENST00000340911.4
ZNF169
zinc finger protein 169
chr1_+_24069952 0.25 ENST00000609199.1
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr6_-_42946888 0.25 ENST00000244546.4
PEX6
peroxisomal biogenesis factor 6
chr2_+_172543919 0.24 ENST00000452242.1
ENST00000340296.4
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr16_-_54963026 0.24 ENST00000560208.1
ENST00000557792.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr19_+_49496705 0.24 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr7_-_99756293 0.24 ENST00000316937.3
ENST00000456769.1
C7orf43
chromosome 7 open reading frame 43
chr14_-_24711764 0.24 ENST00000557921.1
ENST00000558476.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr19_-_19302931 0.24 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr6_-_91296737 0.24 ENST00000369332.3
ENST00000369329.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr14_-_24711806 0.24 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr3_-_10362725 0.24 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
SEC13
SEC13 homolog (S. cerevisiae)
chr19_-_56826157 0.23 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
ZSCAN5A
zinc finger and SCAN domain containing 5A
chr1_-_1208851 0.23 ENST00000488418.1
UBE2J2
ubiquitin-conjugating enzyme E2, J2
chr19_+_49375649 0.23 ENST00000200453.5
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr5_+_73109339 0.23 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr7_+_44240520 0.23 ENST00000496112.1
ENST00000223369.2
YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr15_+_91427726 0.23 ENST00000452243.1
FES
feline sarcoma oncogene
chr1_+_32687971 0.23 ENST00000373586.1
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr12_-_120907374 0.22 ENST00000550458.1
SRSF9
serine/arginine-rich splicing factor 9
chr16_-_74330612 0.22 ENST00000569389.1
ENST00000562888.1
AC009120.4
AC009120.4
chr15_+_74908228 0.22 ENST00000566126.1
CLK3
CDC-like kinase 3
chr3_-_16554881 0.22 ENST00000451036.1
RFTN1
raftlin, lipid raft linker 1
chr10_-_99161033 0.22 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr1_+_43855560 0.22 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr19_-_3971050 0.22 ENST00000545797.2
ENST00000596311.1
DAPK3
death-associated protein kinase 3
chr1_+_24069642 0.22 ENST00000418390.2
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr14_-_21852119 0.21 ENST00000555943.1
SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr15_-_43559055 0.21 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr17_+_79935464 0.21 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr14_-_45431091 0.20 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr19_-_45737469 0.20 ENST00000413988.1
EXOC3L2
exocyst complex component 3-like 2
chr19_-_16682987 0.20 ENST00000431408.1
ENST00000436553.2
ENST00000595753.1
SLC35E1
solute carrier family 35, member E1
chr2_-_96971232 0.20 ENST00000323853.5
SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr16_-_67694129 0.20 ENST00000602320.1
ACD
adrenocortical dysplasia homolog (mouse)
chr2_+_113885138 0.20 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr19_+_56186606 0.20 ENST00000085079.7
EPN1
epsin 1
chr17_-_48450534 0.20 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
MRPL27
mitochondrial ribosomal protein L27
chr2_+_239335449 0.20 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr9_-_139268068 0.20 ENST00000371734.3
ENST00000371732.5
ENST00000315908.7
CARD9
caspase recruitment domain family, member 9
chr22_+_40742497 0.20 ENST00000216194.7
ADSL
adenylosuccinate lyase
chr22_-_42084863 0.19 ENST00000401959.1
ENST00000355257.3
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr6_-_33256664 0.19 ENST00000444176.1
WDR46
WD repeat domain 46
chr2_+_172543967 0.19 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr12_-_120907459 0.19 ENST00000229390.3
SRSF9
serine/arginine-rich splicing factor 9
chr11_+_65770227 0.19 ENST00000527348.1
BANF1
barrier to autointegration factor 1
chr19_-_10514184 0.19 ENST00000589629.1
ENST00000222005.2
CDC37
cell division cycle 37
chr21_-_46340770 0.19 ENST00000397854.3
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr8_+_104427581 0.19 ENST00000521716.1
ENST00000521971.1
ENST00000519682.1
DCAF13
DDB1 and CUL4 associated factor 13
chr3_+_111805262 0.19 ENST00000484828.1
C3orf52
chromosome 3 open reading frame 52
chr6_-_91296602 0.19 ENST00000369325.3
ENST00000369327.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr5_+_36152091 0.19 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr6_+_30294612 0.19 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
TRIM39
tripartite motif containing 39
chr19_-_54619006 0.19 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr14_+_24701870 0.19 ENST00000561035.1
ENST00000559409.1
ENST00000558865.1
ENST00000558279.1
GMPR2
guanosine monophosphate reductase 2
chr15_+_75074915 0.19 ENST00000567123.1
ENST00000569462.1
CSK
c-src tyrosine kinase
chr17_+_18218587 0.19 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr4_-_185269050 0.19 ENST00000511465.1
RP11-290F5.2
RP11-290F5.2
chr2_+_99771527 0.19 ENST00000415142.1
ENST00000436234.1
LIPT1
lipoyltransferase 1
chr6_-_31619697 0.19 ENST00000434444.1
BAG6
BCL2-associated athanogene 6
chr11_+_70244510 0.19 ENST00000346329.3
ENST00000301843.8
ENST00000376561.3
CTTN
cortactin
chr15_+_91427691 0.18 ENST00000559355.1
ENST00000394302.1
FES
feline sarcoma oncogene
chr19_-_13044494 0.18 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr6_-_656963 0.18 ENST00000380907.2
HUS1B
HUS1 checkpoint homolog b (S. pombe)
chr6_-_31697563 0.18 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr4_-_10118469 0.18 ENST00000499869.2
WDR1
WD repeat domain 1
chr11_-_116658758 0.18 ENST00000227322.3
ZNF259
zinc finger protein 259
chr19_+_56186557 0.18 ENST00000270460.6
EPN1
epsin 1
chr3_-_169482840 0.18 ENST00000602385.1
TERC
telomerase RNA component
chr19_+_50919056 0.18 ENST00000599632.1
CTD-2545M3.6
CTD-2545M3.6
chr1_-_55266865 0.18 ENST00000371274.4
TTC22
tetratricopeptide repeat domain 22
chr17_-_55927370 0.18 ENST00000578444.1
ENST00000313608.8
ENST00000579380.1
MRPS23
mitochondrial ribosomal protein S23
chr6_+_30295036 0.17 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr2_+_96931834 0.17 ENST00000488633.1
CIAO1
cytosolic iron-sulfur protein assembly 1
chr11_+_7041677 0.17 ENST00000299481.4
NLRP14
NLR family, pyrin domain containing 14
chr1_-_43855479 0.17 ENST00000290663.6
ENST00000372457.4
MED8
mediator complex subunit 8
chr17_-_26989136 0.17 ENST00000247020.4
SDF2
stromal cell-derived factor 2
chr5_+_147763498 0.17 ENST00000340253.5
FBXO38
F-box protein 38
chr17_+_46048497 0.17 ENST00000583352.1
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr2_-_95831158 0.17 ENST00000447814.1
ZNF514
zinc finger protein 514
chr21_-_46340884 0.17 ENST00000302347.5
ENST00000517819.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr17_+_46048471 0.17 ENST00000578018.1
ENST00000579175.1
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr11_+_47600562 0.17 ENST00000263774.4
ENST00000529276.1
ENST00000528192.1
ENST00000530295.1
ENST00000534208.1
ENST00000534716.2
NDUFS3
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
chr11_+_68671310 0.17 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr12_+_27863706 0.17 ENST00000081029.3
ENST00000538315.1
ENST00000542791.1
MRPS35
mitochondrial ribosomal protein S35
chr6_+_43603552 0.17 ENST00000372171.4
MAD2L1BP
MAD2L1 binding protein
chr11_+_64851666 0.17 ENST00000525509.1
ENST00000294258.3
ENST00000526334.1
ZFPL1
zinc finger protein-like 1
chr6_-_125623046 0.17 ENST00000608295.1
ENST00000398153.2
ENST00000608284.1
ENST00000368377.4
HDDC2
HD domain containing 2
chr14_+_105864847 0.16 ENST00000451127.2
TEX22
testis expressed 22
chr8_-_104427313 0.16 ENST00000297578.4
SLC25A32
solute carrier family 25 (mitochondrial folate carrier), member 32
chr15_+_75074410 0.16 ENST00000439220.2
CSK
c-src tyrosine kinase
chr17_-_76836729 0.16 ENST00000587783.1
ENST00000542802.3
ENST00000586531.1
ENST00000589424.1
ENST00000590546.2
USP36
ubiquitin specific peptidase 36
chr16_-_67693846 0.16 ENST00000602850.1
ACD
adrenocortical dysplasia homolog (mouse)
chr19_-_6393216 0.16 ENST00000595047.1
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
chr11_+_327171 0.16 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr5_+_34839260 0.16 ENST00000505624.1
TTC23L
tetratricopeptide repeat domain 23-like
chr11_-_6704513 0.16 ENST00000532203.1
ENST00000288937.6
MRPL17
mitochondrial ribosomal protein L17
chr8_-_145980808 0.16 ENST00000525191.1
ZNF251
zinc finger protein 251
chr4_-_10118573 0.16 ENST00000382452.2
ENST00000382451.2
WDR1
WD repeat domain 1
chr17_-_2239729 0.16 ENST00000576112.2
TSR1
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
chr1_+_156698743 0.16 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr17_+_30813576 0.16 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr10_+_26986582 0.16 ENST00000376215.5
ENST00000376203.5
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr17_+_4843303 0.16 ENST00000571816.1
RNF167
ring finger protein 167
chr17_-_61777459 0.16 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr16_-_15736953 0.16 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
KIAA0430
chr21_+_46654249 0.16 ENST00000584169.1
ENST00000328344.2
LINC00334
long intergenic non-protein coding RNA 334
chr6_+_31633833 0.16 ENST00000375882.2
ENST00000375880.2
CSNK2B
CSNK2B-LY6G5B-1181
casein kinase 2, beta polypeptide
Uncharacterized protein
chr11_-_18548426 0.15 ENST00000357193.3
ENST00000536719.1
TSG101
tumor susceptibility 101
chr10_+_75504105 0.15 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24C
SEC24 family member C
chr6_-_31697255 0.15 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr11_-_116658695 0.15 ENST00000429220.1
ENST00000444935.1
ZNF259
zinc finger protein 259
chr19_+_1275917 0.15 ENST00000469144.1
C19orf24
chromosome 19 open reading frame 24
chr1_-_202858227 0.15 ENST00000367262.3
RABIF
RAB interacting factor
chr11_-_65625014 0.15 ENST00000534784.1
CFL1
cofilin 1 (non-muscle)
chr17_-_57784755 0.15 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
PTRH2
peptidyl-tRNA hydrolase 2
chr1_-_38325256 0.15 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr17_-_15587602 0.15 ENST00000416464.2
ENST00000578237.1
ENST00000581200.1
TRIM16
tripartite motif containing 16
chr7_+_44084262 0.15 ENST00000456905.1
ENST00000440166.1
ENST00000452943.1
ENST00000468694.1
ENST00000494774.1
ENST00000490734.2
DBNL
drebrin-like
chr8_-_124054484 0.15 ENST00000419562.2
DERL1
derlin 1
chr6_+_30524663 0.15 ENST00000376560.3
PRR3
proline rich 3
chr18_-_45456930 0.15 ENST00000262160.6
ENST00000587269.1
SMAD2
SMAD family member 2
chr4_-_5710257 0.15 ENST00000344938.1
ENST00000344408.5
EVC2
Ellis van Creveld syndrome 2
chr3_+_45635661 0.15 ENST00000440097.1
LIMD1
LIM domains containing 1
chr2_+_241544834 0.15 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
GPR35
G protein-coupled receptor 35
chr1_+_84944926 0.15 ENST00000370656.1
ENST00000370654.5
RPF1
ribosome production factor 1 homolog (S. cerevisiae)
chr1_+_154193643 0.15 ENST00000456325.1
UBAP2L
ubiquitin associated protein 2-like
chr14_-_100842588 0.15 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
WARS
tryptophanyl-tRNA synthetase
chr19_+_56166360 0.15 ENST00000308924.4
U2AF2
U2 small nuclear RNA auxiliary factor 2
chr1_-_19811962 0.15 ENST00000375142.1
ENST00000264202.6
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr6_-_31619742 0.15 ENST00000433828.1
ENST00000456286.1
BAG6
BCL2-associated athanogene 6
chr19_+_11546440 0.15 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr6_+_57182400 0.15 ENST00000607273.1
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr6_-_31697977 0.15 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_-_1876156 0.15 ENST00000565797.1
CTB-31O20.2
CTB-31O20.2
chr19_-_10230540 0.15 ENST00000589454.1
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr2_+_201981119 0.14 ENST00000395148.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr10_+_102729249 0.14 ENST00000519649.1
ENST00000518124.1
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_-_43638168 0.14 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 1.9 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.2 0.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 0.8 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 0.8 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.4 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 1.0 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.5 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.4 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.5 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 1.0 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.2 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.7 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.3 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.2 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 0.2 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.2 GO:2000397 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.3 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0032618 interleukin-15 production(GO:0032618)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 3.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.5 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.4 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0052363 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.3 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 1.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) synaptic transmission involved in micturition(GO:0060084)
0.0 0.6 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.6 GO:0030539 male genitalia development(GO:0030539)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.4 GO:0007252 activation of NF-kappaB-inducing kinase activity(GO:0007250) I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 1.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.0 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation(GO:0060051) negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.2 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.2 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.8 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.0 GO:1903423 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0048757 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.2 1.9 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:0042565 nuclear RNA export factor complex(GO:0042272) RNA nuclear export complex(GO:0042565)
0.1 0.5 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.8 GO:0097255 R2TP complex(GO:0097255)
0.1 0.2 GO:0035101 FACT complex(GO:0035101)
0.1 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 1.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 2.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.5 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0000776 kinetochore(GO:0000776)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.0 GO:0044753 amphisome(GO:0044753)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.5 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.7 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.3 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.2 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 1.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.6 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.4 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 2.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.0 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.0 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.0 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 1.0 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.7 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 0.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing