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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EVX2

Z-value: 0.25

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Transcription factors associated with EVX2

Gene Symbol Gene ID Gene Info
EVX2
ENSG00000174279.4 even-skipped homeobox 2

Activity profile of EVX2 motif

Sorted Z-values of EVX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_111718173 0.11 ENST00000494932.1
TAGLN3
transgelin 3
chr17_+_37809333 0.09 ENST00000443521.1
STARD3
StAR-related lipid transfer (START) domain containing 3
chr15_+_41057818 0.07 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr4_-_41884620 0.07 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr3_+_111717511 0.06 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr13_+_78315528 0.06 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr3_+_111717600 0.06 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_111718036 0.06 ENST00000455401.2
TAGLN3
transgelin 3
chr12_+_64798826 0.06 ENST00000540203.1
XPOT
exportin, tRNA
chr6_-_62996066 0.05 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr15_-_55562582 0.04 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55563072 0.04 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr20_+_43990576 0.04 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr1_+_28261533 0.03 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr13_+_78315466 0.03 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr19_+_11071546 0.03 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr15_-_55562479 0.03 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr4_+_144354644 0.02 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr4_+_144312659 0.02 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr17_-_40337470 0.02 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr17_-_9929581 0.01 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr1_-_159832438 0.01 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr3_+_115342349 0.01 ENST00000393780.3
GAP43
growth associated protein 43
chr20_+_30467600 0.01 ENST00000375934.4
ENST00000375922.4
TTLL9
tubulin tyrosine ligase-like family, member 9
chr1_+_28261492 0.01 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr11_+_65554493 0.01 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr6_-_111927062 0.00 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr1_-_151431674 0.00 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr12_+_15699286 0.00 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O

Network of associatons between targets according to the STRING database.

First level regulatory network of EVX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)