ISMARA results: EZH2

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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EZH2

Z-value: 1.39

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Transcription factors associated with EZH2

Gene Symbol	Gene ID	Gene Info
EZH2 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000106462.6	enhancer of zeste 2 polycomb repressive complex 2 subunit

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
EZH2	hg19_v2_chr7_-_148581251_148581347	-0.90	1.4e-02	Click!

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_-_41740181 Show fit	2.14	ENST00000442711.1	INHBA Ensembl NCBI GeneCards UniProt NextProt Show fit	inhibin, beta A
chr6_-_31550192 Show fit	1.45	ENST00000429299.2 ENST00000446745.2	LTB Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphotoxin beta (TNF superfamily, member 3)
chr12_+_7167980 Show fit	1.27	ENST00000360817.5 ENST00000402681.3	C1S Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, s subcomponent
chrY_+_15418467 Show fit	1.26	ENST00000595988.1	AC010877.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Uncharacterized protein
chr6_+_31543334 Show fit	1.23	ENST00000449264.2	TNF Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor
chr2_+_228678550 Show fit	1.03	ENST00000409189.3 ENST00000358813.4	CCL20 Ensembl NCBI GeneCards UniProt NextProt Show fit	chemokine (C-C motif) ligand 20
chr5_+_92919043 Show fit	0.99	ENST00000327111.3	NR2F1 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 2, group F, member 1
chr2_+_45168875 Show fit	0.98	ENST00000260653.3	SIX3 Ensembl NCBI GeneCards UniProt NextProt Show fit	SIX homeobox 3
chr6_+_31895467 Show fit	0.94	ENST00000556679.1 ENST00000456570.1	CFB Ensembl NCBI GeneCards UniProt NextProt Show fit CFB Ensembl NCBI GeneCards UniProt NextProt Show fit	complement factor B Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31895480 Show fit	0.85	ENST00000418949.2 ENST00000383177.3 ENST00000477310.1	C2 Ensembl NCBI GeneCards UniProt NextProt Show fit CFB Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 2 Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31730773 Show fit	0.79	ENST00000415669.2 ENST00000425424.1	SAPCD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	suppressor APC domain containing 1
chr5_-_146461027 Show fit	0.76	ENST00000394410.2 ENST00000508267.1 ENST00000504198.1	PPP2R2B Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2, regulatory subunit B, beta
chr11_-_66496655 Show fit	0.72	ENST00000527010.1	SPTBN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	spectrin, beta, non-erythrocytic 2
chrX_+_28605516 Show fit	0.62	ENST00000378993.1	IL1RAPL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 1 receptor accessory protein-like 1
chr12_+_120502441 Show fit	0.62	ENST00000446727.2	CCDC64 Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 64
chr17_+_7533439 Show fit	0.60	ENST00000441599.2 ENST00000380450.4 ENST00000416273.3 ENST00000575903.1 ENST00000576830.1 ENST00000571153.1 ENST00000575618.1 ENST00000576152.1	SHBG Ensembl NCBI GeneCards UniProt NextProt Show fit	sex hormone-binding globulin
chr11_-_102826434 Show fit	0.57	ENST00000340273.4 ENST00000260302.3	MMP13 Ensembl NCBI GeneCards UniProt NextProt Show fit	matrix metallopeptidase 13 (collagenase 3)
chrX_+_48681768 Show fit	0.54	ENST00000430858.1	HDAC6 Ensembl NCBI GeneCards UniProt NextProt Show fit	histone deacetylase 6
chr5_-_40835303 Show fit	0.54	ENST00000509877.1 ENST00000508493.1 ENST00000274242.5	RPL37 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L37
chr2_-_113594279 Show fit	0.53	ENST00000416750.1 ENST00000418817.1 ENST00000263341.2	IL1B Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 1, beta
chr7_-_117512264 Show fit	0.52	ENST00000454375.1	CTTNBP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	cortactin binding protein 2
chr19_-_35626104 Show fit	0.52	ENST00000310123.3 ENST00000392225.3	LGI4 Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine-rich repeat LGI family, member 4
chrX_-_100662881 Show fit	0.51	ENST00000218516.3	GLA Ensembl NCBI GeneCards UniProt NextProt Show fit	galactosidase, alpha
chr17_-_76356148 Show fit	0.50	ENST00000587578.1 ENST00000330871.2	SOCS3 Ensembl NCBI GeneCards UniProt NextProt Show fit	suppressor of cytokine signaling 3
chr8_-_42065075 Show fit	0.49	ENST00000429089.2 ENST00000519510.1 ENST00000429710.2 ENST00000524009.1	PLAT Ensembl NCBI GeneCards UniProt NextProt Show fit	plasminogen activator, tissue
chr12_-_7244469 Show fit	0.49	ENST00000538050.1 ENST00000536053.2	C1R Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, r subcomponent
chr17_+_38334501 Show fit	0.47	ENST00000541245.1	RAPGEFL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rap guanine nucleotide exchange factor (GEF)-like 1
chr17_-_73285293 Show fit	0.47	ENST00000582778.1 ENST00000581988.1 ENST00000579207.1 ENST00000583332.1 ENST00000416858.2 ENST00000442286.2 ENST00000580151.1 ENST00000580994.1 ENST00000584438.1 ENST00000320362.3 ENST00000580273.1	SLC25A19 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr11_+_64004888 Show fit	0.46	ENST00000541681.1	VEGFB Ensembl NCBI GeneCards UniProt NextProt Show fit	vascular endothelial growth factor B
chr4_+_74735102 Show fit	0.45	ENST00000395761.3	CXCL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chrX_-_48326764 Show fit	0.45	ENST00000413668.1 ENST00000441948.1	SLC38A5 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 38, member 5
chr1_+_152881014 Show fit	0.44	ENST00000368764.3 ENST00000392667.2	IVL Ensembl NCBI GeneCards UniProt NextProt Show fit	involucrin
chr11_+_123430948 Show fit	0.44	ENST00000529432.1 ENST00000534764.1	GRAMD1B Ensembl NCBI GeneCards UniProt NextProt Show fit	GRAM domain containing 1B
chr15_-_43559055 Show fit	0.44	ENST00000220420.5 ENST00000349114.4	TGM5 Ensembl NCBI GeneCards UniProt NextProt Show fit	transglutaminase 5
chr17_-_76719638 Show fit	0.43	ENST00000587308.1	CYTH1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cytohesin 1
chr3_-_195538760 Show fit	0.43	ENST00000475231.1	MUC4 Ensembl NCBI GeneCards UniProt NextProt Show fit	mucin 4, cell surface associated
chr9_-_33402506 Show fit	0.42	ENST00000377425.4 ENST00000537089.1 ENST00000297988.1 ENST00000539936.1 ENST00000541274.1	AQP7 Ensembl NCBI GeneCards UniProt NextProt Show fit	aquaporin 7
chr12_+_113376249 Show fit	0.42	ENST00000551007.1 ENST00000548514.1	OAS3 Ensembl NCBI GeneCards UniProt NextProt Show fit	2'-5'-oligoadenylate synthetase 3, 100kDa
chr8_+_55467072 Show fit	0.42	ENST00000602362.1	RP11-53M11.3 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-53M11.3
chr12_+_113376157 Show fit	0.42	ENST00000228928.7	OAS3 Ensembl NCBI GeneCards UniProt NextProt Show fit	2'-5'-oligoadenylate synthetase 3, 100kDa
chr8_+_61592073 Show fit	0.42	ENST00000526846.1	CHD7 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromodomain helicase DNA binding protein 7
chr1_-_155112883 Show fit	0.41	ENST00000368399.1 ENST00000368400.4 ENST00000341298.3	DPM3 Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-phosphate mannosyltransferase polypeptide 3
chr2_-_31637560 Show fit	0.41	ENST00000379416.3	XDH Ensembl NCBI GeneCards UniProt NextProt Show fit	xanthine dehydrogenase
chr16_+_31483451 Show fit	0.40	ENST00000565360.1 ENST00000361773.3	TGFB1I1 Ensembl NCBI GeneCards UniProt NextProt Show fit	transforming growth factor beta 1 induced transcript 1
chr10_-_106240032 Show fit	0.40	ENST00000447860.1	RP11-127O4.3 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-127O4.3
chr16_+_58033450 Show fit	0.40	ENST00000561743.1	USB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	U6 snRNA biogenesis 1
chr12_+_7022909 Show fit	0.40	ENST00000537688.1	ENO2 Ensembl NCBI GeneCards UniProt NextProt Show fit	enolase 2 (gamma, neuronal)
chr1_+_154193643 Show fit	0.39	ENST00000456325.1	UBAP2L Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin associated protein 2-like
chr7_-_124405681 Show fit	0.39	ENST00000303921.2	GPR37 Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 37 (endothelin receptor type B-like)
chrX_-_153141783 Show fit	0.38	ENST00000458029.1	L1CAM Ensembl NCBI GeneCards UniProt NextProt Show fit	L1 cell adhesion molecule
chr12_-_116714564 Show fit	0.37	ENST00000548743.1	MED13L Ensembl NCBI GeneCards UniProt NextProt Show fit	mediator complex subunit 13-like
chr6_+_32132360 Show fit	0.37	ENST00000333845.6 ENST00000395512.1 ENST00000432129.1	EGFL8 Ensembl NCBI GeneCards UniProt NextProt Show fit	EGF-like-domain, multiple 8
chr17_+_7387677 Show fit	0.37	ENST00000322644.6	POLR2A Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr6_+_13272904 Show fit	0.36	ENST00000379335.3 ENST00000379329.1	PHACTR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatase and actin regulator 1
chr8_+_40010989 Show fit	0.36	ENST00000315792.3	C8orf4 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 8 open reading frame 4
chr6_+_12958137 Show fit	0.35	ENST00000457702.2 ENST00000379345.2	PHACTR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatase and actin regulator 1
chr15_+_90544532 Show fit	0.35	ENST00000268154.4	ZNF710 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 710
chr7_-_139756791 Show fit	0.35	ENST00000489809.1	PARP12 Ensembl NCBI GeneCards UniProt NextProt Show fit	poly (ADP-ribose) polymerase family, member 12
chr3_-_48229846 Show fit	0.35	ENST00000302506.3 ENST00000351231.3 ENST00000437972.1	CDC25A Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 25A
chr17_-_46806540 Show fit	0.35	ENST00000290295.7	HOXB13 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox B13
chr6_+_126240442 Show fit	0.34	ENST00000448104.1 ENST00000438495.1 ENST00000444128.1	NCOA7 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor coactivator 7
chr3_+_47324424 Show fit	0.34	ENST00000437353.1 ENST00000232766.5 ENST00000455924.2	KLHL18 Ensembl NCBI GeneCards UniProt NextProt Show fit	kelch-like family member 18
chr19_-_51289436 Show fit	0.34	ENST00000562076.1	CTD-2568A17.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	CTD-2568A17.1
chr3_-_197300194 Show fit	0.34	ENST00000358186.2 ENST00000431056.1	BDH1 Ensembl NCBI GeneCards UniProt NextProt Show fit	3-hydroxybutyrate dehydrogenase, type 1
chr1_+_95975672 Show fit	0.34	ENST00000440116.2 ENST00000456933.1	RP11-286B14.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-286B14.1
chr17_+_38119216 Show fit	0.34	ENST00000301659.4	GSDMA Ensembl NCBI GeneCards UniProt NextProt Show fit	gasdermin A
chr10_+_12391685 Show fit	0.34	ENST00000378845.1	CAMK1D Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium/calmodulin-dependent protein kinase ID
chr13_-_108518986 Show fit	0.33	ENST00000375915.2	FAM155A Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 155, member A
chr9_-_16870704 Show fit	0.32	ENST00000380672.4 ENST00000380667.2 ENST00000380666.2 ENST00000486514.1	BNC2 Ensembl NCBI GeneCards UniProt NextProt Show fit	basonuclin 2
chr10_-_75682535 Show fit	0.32	ENST00000409178.1	C10orf55 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 10 open reading frame 55
chr15_+_84906338 Show fit	0.32	ENST00000512109.1	GOLGA6L4 Ensembl NCBI GeneCards UniProt NextProt Show fit	golgin A6 family-like 4
chr9_+_130911723 Show fit	0.32	ENST00000277480.2 ENST00000373013.2 ENST00000540948.1	LCN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	lipocalin 2
chr5_+_149865377 Show fit	0.32	ENST00000522491.1	NDST1 Ensembl NCBI GeneCards UniProt NextProt Show fit	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr6_-_134639180 Show fit	0.32	ENST00000367858.5	SGK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	serum/glucocorticoid regulated kinase 1
chr10_+_91152303 Show fit	0.32	ENST00000371804.3	IFIT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon-induced protein with tetratricopeptide repeats 1
chr5_-_147162078 Show fit	0.31	ENST00000507386.1	JAKMIP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	janus kinase and microtubule interacting protein 2
chr14_-_45431091 Show fit	0.31	ENST00000579157.1 ENST00000396128.4 ENST00000556500.1	KLHL28 Ensembl NCBI GeneCards UniProt NextProt Show fit	kelch-like family member 28
chr12_-_58159361 Show fit	0.31	ENST00000546567.1	CYP27B1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome P450, family 27, subfamily B, polypeptide 1
chrX_-_24665353 Show fit	0.31	ENST00000379144.2	PCYT1B Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphate cytidylyltransferase 1, choline, beta
chr1_+_209859510 Show fit	0.31	ENST00000367028.2 ENST00000261465.1	HSD11B1 Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid (11-beta) dehydrogenase 1
chr5_-_20575959 Show fit	0.31	ENST00000507958.1	CDH18 Ensembl NCBI GeneCards UniProt NextProt Show fit	cadherin 18, type 2
chr16_-_11367452 Show fit	0.30	ENST00000327157.2	PRM3 Ensembl NCBI GeneCards UniProt NextProt Show fit	protamine 3
chr17_+_27047570 Show fit	0.30	ENST00000472628.1 ENST00000578181.1	RPL23A Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L23a
chr6_-_131277510 Show fit	0.30	ENST00000525193.1 ENST00000527659.1	EPB41L2 Ensembl NCBI GeneCards UniProt NextProt Show fit	erythrocyte membrane protein band 4.1-like 2
chr9_+_133971909 Show fit	0.30	ENST00000247291.3 ENST00000372302.1 ENST00000372300.1 ENST00000372298.1	AIF1L Ensembl NCBI GeneCards UniProt NextProt Show fit	allograft inflammatory factor 1-like
chr3_+_109128961 Show fit	0.30	ENST00000489670.1	RP11-702L6.4 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-702L6.4
chr9_-_116061476 Show fit	0.30	ENST00000441031.3	RNF183 Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 183
chr14_-_94443105 Show fit	0.30	ENST00000555019.1	ASB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat and SOCS box containing 2
chr6_+_12290586 Show fit	0.29	ENST00000379375.5	EDN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	endothelin 1
chr1_+_154193325 Show fit	0.29	ENST00000428931.1 ENST00000441890.1 ENST00000271877.7 ENST00000412596.1 ENST00000368504.1 ENST00000437652.1	UBAP2L Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin associated protein 2-like
chr15_-_65117807 Show fit	0.29	ENST00000559239.1 ENST00000268043.4 ENST00000333425.6	PIF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	PIF1 5'-to-3' DNA helicase
chr12_-_49582978 Show fit	0.29	ENST00000301071.7	TUBA1A Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin, alpha 1a
chr16_-_58033762 Show fit	0.29	ENST00000299237.2	ZNF319 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 319
chr17_-_40134339 Show fit	0.29	ENST00000587727.1	DNAJC7 Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily C, member 7
chr3_+_109128837 Show fit	0.29	ENST00000497996.1	RP11-702L6.4 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-702L6.4
chr11_+_114168773 Show fit	0.29	ENST00000542647.1 ENST00000545255.1	NNMT Ensembl NCBI GeneCards UniProt NextProt Show fit	nicotinamide N-methyltransferase
chr19_-_7698599 Show fit	0.28	ENST00000311069.5	PCP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	Purkinje cell protein 2
chr5_-_180235755 Show fit	0.28	ENST00000502678.1	MGAT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr8_+_128748308 Show fit	0.28	ENST00000377970.2	MYC Ensembl NCBI GeneCards UniProt NextProt Show fit	v-myc avian myelocytomatosis viral oncogene homolog
chr6_-_31613280 Show fit	0.28	ENST00000453833.1	BAG6 Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-associated athanogene 6
chr6_-_167276033 Show fit	0.28	ENST00000503859.1 ENST00000506565.1	RPS6KA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_+_30848829 Show fit	0.28	ENST00000508317.1	DDR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	discoidin domain receptor tyrosine kinase 1
chr2_+_217363559 Show fit	0.28	ENST00000600880.1 ENST00000446558.1	RPL37A Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L37a
chr19_-_39881669 Show fit	0.28	ENST00000221266.7	PAF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr9_+_131902283 Show fit	0.28	ENST00000436883.1 ENST00000414510.1	PPP2R4 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2A activator, regulatory subunit 4
chr10_+_30723105 Show fit	0.28	ENST00000375322.2	MAP3K8 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr12_-_49582593 Show fit	0.28	ENST00000295766.5	TUBA1A Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin, alpha 1a
chrX_-_19688475 Show fit	0.28	ENST00000541422.1	SH3KBP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3-domain kinase binding protein 1
chr15_+_44084503 Show fit	0.28	ENST00000409960.2 ENST00000409646.1 ENST00000594896.1 ENST00000339624.5 ENST00000409291.1 ENST00000402131.1 ENST00000403425.1 ENST00000430901.1	SERF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	small EDRK-rich factor 2
chr4_+_160188889 Show fit	0.28	ENST00000264431.4	RAPGEF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rap guanine nucleotide exchange factor (GEF) 2
chr9_+_104296163 Show fit	0.27	ENST00000374819.2 ENST00000479306.1	RNF20 Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 20, E3 ubiquitin protein ligase
chr5_+_175298674 Show fit	0.27	ENST00000514150.1	CPLX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	complexin 2
chr12_-_7245018 Show fit	0.27	ENST00000543835.1 ENST00000535233.2	C1R Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, r subcomponent
chr11_-_66496430 Show fit	0.26	ENST00000533211.1	SPTBN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	spectrin, beta, non-erythrocytic 2
chr5_+_147582348 Show fit	0.26	ENST00000514389.1	SPINK6 Ensembl NCBI GeneCards UniProt NextProt Show fit	serine peptidase inhibitor, Kazal type 6
chr17_-_7123021 Show fit	0.26	ENST00000399510.2	DLG4 Ensembl NCBI GeneCards UniProt NextProt Show fit	discs, large homolog 4 (Drosophila)
chr21_+_17792672 Show fit	0.26	ENST00000602620.1	LINC00478 Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 478
chr4_+_156588115 Show fit	0.26	ENST00000455639.2	GUCY1A3 Ensembl NCBI GeneCards UniProt NextProt Show fit	guanylate cyclase 1, soluble, alpha 3
chr5_+_175298487 Show fit	0.26	ENST00000393745.3	CPLX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	complexin 2
chrX_+_133941218 Show fit	0.26	ENST00000370784.4 ENST00000370785.3	FAM122C Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 122C
chr19_+_19303720 Show fit	0.26	ENST00000392324.4	RFXANK Ensembl NCBI GeneCards UniProt NextProt Show fit	regulatory factor X-associated ankyrin-containing protein
chr4_+_156588249 Show fit	0.26	ENST00000393832.3	GUCY1A3 Ensembl NCBI GeneCards UniProt NextProt Show fit	guanylate cyclase 1, soluble, alpha 3
chr6_-_79944336 Show fit	0.26	ENST00000344726.5 ENST00000275036.7	HMGN3 Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group nucleosomal binding domain 3
chr16_+_30075783 Show fit	0.26	ENST00000412304.2	ALDOA Ensembl NCBI GeneCards UniProt NextProt Show fit	aldolase A, fructose-bisphosphate
chr20_-_35580240 Show fit	0.26	ENST00000262878.4	SAMHD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	SAM domain and HD domain 1
chr2_+_220462560 Show fit	0.26	ENST00000456909.1 ENST00000295641.10	STK11IP Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/threonine kinase 11 interacting protein
chr16_+_30709530 Show fit	0.26	ENST00000411466.2	SRCAP Ensembl NCBI GeneCards UniProt NextProt Show fit	Snf2-related CREBBP activator protein
chr11_-_132813627 Show fit	0.25	ENST00000374778.4	OPCML Ensembl NCBI GeneCards UniProt NextProt Show fit	opioid binding protein/cell adhesion molecule-like
chr16_-_58034357 Show fit	0.25	ENST00000562909.1	ZNF319 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 319
chr10_+_1102303 Show fit	0.25	ENST00000381329.1	WDR37 Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 37
chr19_-_54604083 Show fit	0.25	ENST00000391761.1 ENST00000356532.3 ENST00000359649.4 ENST00000358375.4 ENST00000391760.1 ENST00000351806.4	OSCAR Ensembl NCBI GeneCards UniProt NextProt Show fit	osteoclast associated, immunoglobulin-like receptor
chr5_+_140571902 Show fit	0.25	ENST00000239446.4	PCDHB10 Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin beta 10
chr9_-_112970436 Show fit	0.25	ENST00000400613.4	C9orf152 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 9 open reading frame 152
chr13_-_72441315 Show fit	0.25	ENST00000305425.4 ENST00000313174.7 ENST00000354591.4	DACH1 Ensembl NCBI GeneCards UniProt NextProt Show fit	dachshund homolog 1 (Drosophila)
chr3_-_47324242 Show fit	0.24	ENST00000456548.1 ENST00000432493.1 ENST00000335044.2 ENST00000444589.2	KIF9 Ensembl NCBI GeneCards UniProt NextProt Show fit	kinesin family member 9
chr19_-_39881777 Show fit	0.24	ENST00000595564.1 ENST00000221265.3	PAF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr16_-_30569584 Show fit	0.24	ENST00000252797.2 ENST00000568114.1	ZNF764 Ensembl NCBI GeneCards UniProt NextProt Show fit AC002310.13 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 764 Uncharacterized protein
chr20_+_62795827 Show fit	0.24	ENST00000328439.1 ENST00000536311.1	MYT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin transcription factor 1
chr6_-_75915757 Show fit	0.24	ENST00000322507.8	COL12A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen, type XII, alpha 1
chr3_-_120400960 Show fit	0.24	ENST00000476082.2	HGD Ensembl NCBI GeneCards UniProt NextProt Show fit	homogentisate 1,2-dioxygenase
chr16_-_19725899 Show fit	0.24	ENST00000567367.1	KNOP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine-rich nucleolar protein 1
chr5_+_145317356 Show fit	0.24	ENST00000511217.1	SH3RF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3 domain containing ring finger 2
chr16_-_69419473 Show fit	0.24	ENST00000566750.1	TERF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	telomeric repeat binding factor 2
chr11_-_65667884 Show fit	0.24	ENST00000448083.2 ENST00000531493.1 ENST00000532401.1	FOSL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	FOS-like antigen 1
chr14_-_81408031 Show fit	0.23	ENST00000216517.6	CEP128 Ensembl NCBI GeneCards UniProt NextProt Show fit	centrosomal protein 128kDa
chr10_+_18629628 Show fit	0.23	ENST00000377329.4	CACNB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium channel, voltage-dependent, beta 2 subunit
chr9_-_71869642 Show fit	0.23	ENST00000600472.1	AL358113.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Tight junction protein 2 (Zona occludens 2) isoform 1 variant; Uncharacterized protein
chr15_+_43885799 Show fit	0.23	ENST00000449946.1 ENST00000417289.1	CKMT1B Ensembl NCBI GeneCards UniProt NextProt Show fit	creatine kinase, mitochondrial 1B
chr17_+_77030267 Show fit	0.23	ENST00000581774.1	C1QTNF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	C1q and tumor necrosis factor related protein 1
chr1_+_214161272 Show fit	0.23	ENST00000498508.2 ENST00000366958.4	PROX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	prospero homeobox 1
chrY_-_15591485 Show fit	0.23	ENST00000382896.4 ENST00000537580.1 ENST00000540140.1 ENST00000545955.1 ENST00000538878.1	UTY Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr10_+_30723045 Show fit	0.23	ENST00000542547.1 ENST00000415139.1	MAP3K8 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase kinase kinase 8
chrX_+_69488174 Show fit	0.23	ENST00000480877.2 ENST00000307959.8	ARR3 Ensembl NCBI GeneCards UniProt NextProt Show fit	arrestin 3, retinal (X-arrestin)
chr11_+_60614946 Show fit	0.23	ENST00000545580.1	CCDC86 Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 86
chr14_+_39703112 Show fit	0.23	ENST00000555143.1 ENST00000280082.3	MIA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma inhibitory activity 2
chr16_+_30075595 Show fit	0.23	ENST00000563060.2	ALDOA Ensembl NCBI GeneCards UniProt NextProt Show fit	aldolase A, fructose-bisphosphate
chr3_-_114173530 Show fit	0.23	ENST00000470311.1	ZBTB20 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger and BTB domain containing 20
chr4_-_80994471 Show fit	0.23	ENST00000295465.4	ANTXR2 Ensembl NCBI GeneCards UniProt NextProt Show fit	anthrax toxin receptor 2
chr16_+_54964740 Show fit	0.22	ENST00000394636.4	IRX5 Ensembl NCBI GeneCards UniProt NextProt Show fit	iroquois homeobox 5
chr17_+_18218587 Show fit	0.22	ENST00000406438.3	SMCR8 Ensembl NCBI GeneCards UniProt NextProt Show fit	Smith-Magenis syndrome chromosome region, candidate 8
chr8_+_128748466 Show fit	0.22	ENST00000524013.1 ENST00000520751.1	MYC Ensembl NCBI GeneCards UniProt NextProt Show fit	v-myc avian myelocytomatosis viral oncogene homolog
chr12_-_49582837 Show fit	0.22	ENST00000547939.1 ENST00000546918.1 ENST00000552924.1	TUBA1A Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin, alpha 1a
chr12_+_93965451 Show fit	0.22	ENST00000548537.1	SOCS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	suppressor of cytokine signaling 2
chr7_+_100271355 Show fit	0.22	ENST00000436220.1 ENST00000424361.1	GNB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein (G protein), beta polypeptide 2
chrX_-_152989798 Show fit	0.22	ENST00000441714.1 ENST00000442093.1 ENST00000429550.1 ENST00000345046.6	BCAP31 Ensembl NCBI GeneCards UniProt NextProt Show fit	B-cell receptor-associated protein 31
chr19_-_4338783 Show fit	0.22	ENST00000601482.1 ENST00000600324.1	STAP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	signal transducing adaptor family member 2
chr8_+_99956759 Show fit	0.21	ENST00000522510.1 ENST00000457907.2	OSR2 Ensembl NCBI GeneCards UniProt NextProt Show fit	odd-skipped related transciption factor 2
chr17_-_38928414 Show fit	0.21	ENST00000335552.4	KRT26 Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 26
chr10_+_75668916 Show fit	0.21	ENST00000481390.1	PLAU Ensembl NCBI GeneCards UniProt NextProt Show fit	plasminogen activator, urokinase
chr3_-_116164306 Show fit	0.21	ENST00000490035.2	LSAMP Ensembl NCBI GeneCards UniProt NextProt Show fit	limbic system-associated membrane protein
chr15_-_60695071 Show fit	0.21	ENST00000557904.1	ANXA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	annexin A2
chr11_+_64053890 Show fit	0.21	ENST00000438980.2 ENST00000313074.3 ENST00000542190.1 ENST00000541952.1	GPR137 Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 137
chr17_-_45918539 Show fit	0.21	ENST00000584123.1 ENST00000578323.1 ENST00000407215.3 ENST00000290216.9	SCRN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	secernin 2
chr3_-_157823839 Show fit	0.21	ENST00000425436.3 ENST00000389589.4 ENST00000441443.2	SHOX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	short stature homeobox 2
chr16_-_29934558 Show fit	0.21	ENST00000568995.1 ENST00000566413.1	KCTD13 Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium channel tetramerization domain containing 13
chr4_+_84457250 Show fit	0.21	ENST00000395226.2	AGPAT9 Ensembl NCBI GeneCards UniProt NextProt Show fit	1-acylglycerol-3-phosphate O-acyltransferase 9
chr8_+_11666649 Show fit	0.21	ENST00000528643.1 ENST00000525777.1	FDFT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	farnesyl-diphosphate farnesyltransferase 1
chr16_+_56782118 Show fit	0.21	ENST00000566678.1	NUP93 Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 93kDa
chr17_-_46692287 Show fit	0.21	ENST00000239144.4	HOXB8 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox B8
chr14_+_23305760 Show fit	0.21	ENST00000311852.6	MMP14 Ensembl NCBI GeneCards UniProt NextProt Show fit	matrix metallopeptidase 14 (membrane-inserted)
chr16_+_30662085 Show fit	0.21	ENST00000569864.1	PRR14 Ensembl NCBI GeneCards UniProt NextProt Show fit	proline rich 14
chr16_+_30406423 Show fit	0.21	ENST00000524644.1	ZNF48 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 48
chr6_+_30848771 Show fit	0.21	ENST00000503180.1	DDR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	discoidin domain receptor tyrosine kinase 1
chr4_-_54457783 Show fit	0.21	ENST00000263925.7 ENST00000512247.1	LNX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr14_+_92789498 Show fit	0.21	ENST00000531433.1	SLC24A4 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_-_24489842 Show fit	0.20	ENST00000230036.1	GPLD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	glycosylphosphatidylinositol specific phospholipase D1
chr2_+_89952792 Show fit	0.20	ENST00000390265.2	IGKV1D-33 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin kappa variable 1D-33
chr6_-_42713792 Show fit	0.20	ENST00000372876.1	TBCC Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin folding cofactor C
chr7_+_129251531 Show fit	0.20	ENST00000393232.1 ENST00000353868.4 ENST00000539636.1 ENST00000454688.1 ENST00000223190.4 ENST00000311967.2	NRF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear respiratory factor 1
chrX_-_48815633 Show fit	0.20	ENST00000428668.2	OTUD5 Ensembl NCBI GeneCards UniProt NextProt Show fit	OTU domain containing 5
chr12_+_72058130 Show fit	0.20	ENST00000547843.1	THAP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	THAP domain containing, apoptosis associated protein 2
chr7_+_18330035 Show fit	0.20	ENST00000413509.2	HDAC9 Ensembl NCBI GeneCards UniProt NextProt Show fit	histone deacetylase 9
chr13_-_33859819 Show fit	0.20	ENST00000336934.5	STARD13 Ensembl NCBI GeneCards UniProt NextProt Show fit	StAR-related lipid transfer (START) domain containing 13
chr15_+_44084040 Show fit	0.19	ENST00000249786.4	SERF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	small EDRK-rich factor 2
chr18_-_46784778 Show fit	0.19	ENST00000582399.1	DYM Ensembl NCBI GeneCards UniProt NextProt Show fit	dymeclin
chr8_+_22857048 Show fit	0.19	ENST00000251822.6	RHOBTB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho-related BTB domain containing 2
chr11_-_115630900 Show fit	0.19	ENST00000537070.1 ENST00000499809.1 ENST00000514294.2 ENST00000535683.1	LINC00900 Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 900
chr6_+_3259148 Show fit	0.19	ENST00000419065.2 ENST00000473000.2 ENST00000451246.2 ENST00000454610.2	PSMG4 Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) assembly chaperone 4
chr1_+_45265897 Show fit	0.19	ENST00000372201.4	PLK3 Ensembl NCBI GeneCards UniProt NextProt Show fit	polo-like kinase 3
chr10_+_75670862 Show fit	0.19	ENST00000446342.1 ENST00000372764.3 ENST00000372762.4	PLAU Ensembl NCBI GeneCards UniProt NextProt Show fit	plasminogen activator, urokinase

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4	1.2	GO:0045994	positive regulation of translational initiation by iron(GO:0045994)
0.4	1.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.3	1.0	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2	1.4	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1	1.3	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.4	GO:0021553	olfactory nerve development(GO:0021553)
0.1	0.5	GO:0070845	misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1	0.8	GO:0052565	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1	0.5	GO:0090095	regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1	0.7	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.1	0.3	GO:1900215	pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1	0.5	GO:0071934	thiamine transmembrane transport(GO:0071934)
0.1	0.3	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.1	0.4	GO:0046110	xanthine metabolic process(GO:0046110)
0.1	0.5	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.1	0.7	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.1	1.9	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.3	GO:1902396	protein localization to bicellular tight junction(GO:1902396)
0.1	0.2	GO:1900368	regulation of RNA interference(GO:1900368)
0.1	0.4	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.1	0.4	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.1	0.4	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1	0.2	GO:0019836	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1	0.4	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.3	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.2	GO:2001280	myoblast migration involved in skeletal muscle regeneration(GO:0014839) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1	0.3	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.1	0.2	GO:0072194	positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194)
0.1	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1	0.8	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.1	0.6	GO:0014805	smooth muscle adaptation(GO:0014805)
0.1	0.3	GO:0046061	dATP catabolic process(GO:0046061)
0.1	0.4	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1	0.3	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1	0.2	GO:0007113	endomitotic cell cycle(GO:0007113)
0.1	1.0	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1	0.2	GO:0045726	regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1	0.5	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.2	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	0.2	GO:0032207	regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1	0.4	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1	0.2	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1	0.1	GO:1904862	inhibitory synapse assembly(GO:1904862)
0.1	0.2	GO:0052416	multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1	0.4	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1	0.4	GO:0015793	glycerol transport(GO:0015793)
0.1	0.5	GO:0016584	nucleosome positioning(GO:0016584)
0.1	0.6	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	0.5	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.1	0.3	GO:0072619	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1	0.2	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0	0.2	GO:0006540	glutamate decarboxylation to succinate(GO:0006540)
0.0	0.8	GO:0035641	locomotory exploration behavior(GO:0035641)
0.0	0.5	GO:0051001	glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477) negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.2	GO:0002118	aggressive behavior(GO:0002118)
0.0	0.1	GO:1900365	positive regulation of mRNA polyadenylation(GO:1900365)
0.0	0.3	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.0	0.3	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.2	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.3	GO:0046886	positive regulation of hormone biosynthetic process(GO:0046886)
0.0	0.2	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
0.0	0.1	GO:0021569	rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0042660	positive regulation of cell fate specification(GO:0042660)
0.0	0.2	GO:0008204	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0	0.3	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.3	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.0	0.4	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0	0.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.1	GO:1904640	response to methionine(GO:1904640)
0.0	0.4	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.7	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.2	GO:0050925	negative regulation of negative chemotaxis(GO:0050925)
0.0	0.2	GO:1904044	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.0	0.4	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.5	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:1900276	regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0	0.3	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.1	GO:0071474	hyperosmotic response(GO:0006972) cellular hyperosmotic response(GO:0071474)
0.0	0.1	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0	0.6	GO:0015816	glycine transport(GO:0015816)
0.0	0.4	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.3	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.4	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.2	GO:0003185	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0	0.5	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	1.3	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.2	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.2	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.1	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891)
0.0	0.5	GO:1901898	negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	0.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.1	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.0	0.3	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.3	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.1	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.2	GO:1903281	positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0	0.2	GO:0045007	depurination(GO:0045007)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.2	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.2	GO:1904879	membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0	0.6	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.2	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.3	GO:1904327	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0	0.1	GO:0015840	urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.0	0.3	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.0	0.1	GO:0003404	optic vesicle morphogenesis(GO:0003404) optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.0	0.3	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:1904808	regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0019249	lactate biosynthetic process(GO:0019249)
0.0	0.2	GO:1902952	positive regulation of dendritic spine maintenance(GO:1902952)
0.0	0.2	GO:0061588	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0	0.1	GO:0000706	meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0	0.4	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.3	GO:1901185	negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.1	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) pathway-restricted SMAD protein phosphorylation(GO:0060389) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)
0.0	0.1	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.1	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0002368	B cell cytokine production(GO:0002368)
0.0	0.1	GO:1903412	response to bile acid(GO:1903412)
0.0	0.5	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.1	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.2	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.0	0.1	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0	0.3	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.2	GO:0043163	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0	0.1	GO:0097535	lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0	0.1	GO:0036060	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0	0.2	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.3	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.1	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.1	GO:0001555	oocyte growth(GO:0001555)
0.0	0.3	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0	0.2	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.0	0.1	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.3	GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0	0.1	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0002625	regulation of T cell antigen processing and presentation(GO:0002625)
0.0	0.1	GO:1901993	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0	0.1	GO:0072156	distal tubule morphogenesis(GO:0072156)
0.0	0.1	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
0.0	0.3	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0	0.1	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.4	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.4	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.2	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0	0.4	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0	0.1	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0	0.1	GO:1904158	axonemal central apparatus assembly(GO:1904158)
0.0	0.1	GO:1903575	cornified envelope assembly(GO:1903575)
0.0	0.3	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.4	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.8	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.3	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.1	GO:0032690	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0	0.3	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.0	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0	0.2	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.2	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.4	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.0	0.1	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586)
0.0	0.1	GO:0000432	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0	0.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	0.2	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.1	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0042048	olfactory behavior(GO:0042048)
0.0	0.0	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.1	GO:0010669	epithelial structure maintenance(GO:0010669)
0.0	0.1	GO:1990834	response to odorant(GO:1990834)
0.0	0.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.2	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.3	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.1	GO:1990009	retinal cell apoptotic process(GO:1990009)
0.0	0.2	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.0	0.2	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.0	0.1	GO:0055129	L-proline biosynthetic process(GO:0055129)
0.0	0.1	GO:0021861	forebrain radial glial cell differentiation(GO:0021861)
0.0	0.1	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.2	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.3	GO:0051412	response to corticosterone(GO:0051412)
0.0	0.1	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.4	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0098886	modification of dendritic spine(GO:0098886)
0.0	0.1	GO:1990785	response to water-immersion restraint stress(GO:1990785)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0021590	cerebellum maturation(GO:0021590) cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:2001303	lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0	0.2	GO:2001205	negative regulation of osteoclast development(GO:2001205)
0.0	0.0	GO:0071624	positive regulation of granulocyte chemotaxis(GO:0071624)
0.0	0.0	GO:0030073	insulin secretion(GO:0030073)
0.0	0.0	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0	0.2	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.2	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0	0.1	GO:0035640	exploration behavior(GO:0035640)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019) negative regulation of gap junction assembly(GO:1903597)
0.0	0.2	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.2	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.0	GO:0010958	regulation of amino acid import(GO:0010958) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0	0.0	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.1	GO:0099551	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0	0.1	GO:1901631	postsynaptic membrane assembly(GO:0097104) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0	0.1	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.1	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.6	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.1	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0	0.0	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.2	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.1	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.0	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.0	GO:1903445	intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0	0.0	GO:0061055	myotome development(GO:0061055)
0.0	0.4	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	0.1	GO:0010819	regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820)
0.0	0.2	GO:0006929	substrate-dependent cell migration(GO:0006929)
0.0	0.2	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.1	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.4	GO:0061718	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1	0.4	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.6	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1	0.3	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.1	0.2	GO:0005595	collagen type XII trimer(GO:0005595)
0.1	1.4	GO:0008091	spectrin(GO:0008091)
0.1	0.3	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1	0.2	GO:0042565	nuclear RNA export factor complex(GO:0042272) RNA nuclear export complex(GO:0042565)
0.1	0.4	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	0.1	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
0.1	0.2	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.1	0.2	GO:0097598	sperm cytoplasmic droplet(GO:0097598)
0.1	0.5	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	0.2	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.1	0.2	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	1.6	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
0.0	0.3	GO:0070435	Shc-EGFR complex(GO:0070435)
0.0	0.4	GO:0098839	postsynaptic density membrane(GO:0098839)
0.0	0.1	GO:0072517	viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0	0.1	GO:0043257	laminin-8 complex(GO:0043257)
0.0	0.3	GO:0070695	FHF complex(GO:0070695)
0.0	0.3	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.4	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.0	0.1	GO:0034665	integrin alpha1-beta1 complex(GO:0034665)
0.0	0.7	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.9	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.2	GO:0002177	manchette(GO:0002177)
0.0	0.2	GO:0061617	MICOS complex(GO:0061617)
0.0	0.1	GO:0031905	early endosome lumen(GO:0031905)
0.0	0.1	GO:0097444	spine apparatus(GO:0097444)
0.0	0.2	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.3	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.4	GO:0000974	Prp19 complex(GO:0000974)
0.0	4.0	GO:0072562	blood microparticle(GO:0072562)
0.0	0.3	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:1990423	RZZ complex(GO:1990423)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.3	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0044305	calyx of Held(GO:0044305)
0.0	0.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.4	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	0.4	GO:0031932	TORC2 complex(GO:0031932)
0.0	1.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.2	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	1.2	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.1	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0000835	ER ubiquitin ligase complex(GO:0000835)
0.0	0.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.9	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.8	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.1	GO:0038201	TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.0	0.6	GO:0000786	nucleosome(GO:0000786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.2	GO:0034711	inhibin binding(GO:0034711)
0.3	1.0	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.1	0.5	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1	0.9	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.3	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1	0.5	GO:0015234	thiamine transmembrane transporter activity(GO:0015234)
0.1	0.4	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	0.3	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1	0.3	GO:0031705	bombesin receptor binding(GO:0031705)
0.1	0.3	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.1	0.4	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1	0.5	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1	0.3	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1	0.5	GO:0016936	galactoside binding(GO:0016936)
0.1	0.4	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.3	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.1	0.4	GO:0002046	opsin binding(GO:0002046)
0.1	0.5	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	0.5	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.1	0.3	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.1	0.8	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	0.2	GO:0005174	CD40 receptor binding(GO:0005174)
0.1	0.2	GO:0090631	pre-miRNA transporter activity(GO:0090631)
0.1	0.2	GO:0032408	MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1	0.6	GO:0005497	androgen binding(GO:0005497)
0.1	0.2	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	2.0	GO:0001848	complement binding(GO:0001848)
0.1	0.3	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.1	0.7	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.2	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	0.2	GO:0004310	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0	0.6	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.5	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.3	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.2	GO:0016211	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0	0.3	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.0	0.6	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.4	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.3	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.6	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.5	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0	0.7	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.3	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.3	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.9	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.2	GO:0016403	dimethylargininase activity(GO:0016403)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.5	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0	0.3	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.0	0.1	GO:0035651	AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0	0.2	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.3	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.2	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.2	GO:0030171	voltage-gated proton channel activity(GO:0030171)
0.0	0.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.0	1.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.1	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.9	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.5	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.5	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.2	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.9	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0090541	MIT domain binding(GO:0090541)
0.0	0.1	GO:0050436	microfibril binding(GO:0050436)
0.0	0.1	GO:0086040	sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0	0.2	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.3	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.1	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0	0.2	GO:0016015	morphogen activity(GO:0016015) laminin-1 binding(GO:0043237)
0.0	0.1	GO:0016749	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0	0.2	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.0	0.1	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.2	GO:0042835	BRE binding(GO:0042835)
0.0	0.2	GO:0097108	hedgehog family protein binding(GO:0097108)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.3	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.2	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.2	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	0.2	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.0	GO:0035034	histone acetyltransferase regulator activity(GO:0035034)
0.0	0.3	GO:0031432	titin binding(GO:0031432)
0.0	3.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0050115	myosin-light-chain-phosphatase activity(GO:0050115)
0.0	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.2	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.4	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.2	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.0	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0047977	linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0	0.0	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	0.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.3	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.3	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0	0.6	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.0	GO:0016005	phospholipase A2 activator activity(GO:0016005)
0.0	0.2	GO:0001055	RNA polymerase II activity(GO:0001055)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	2.1	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	2.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.6	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.7	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.8	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.4	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.5	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	1.0	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.6	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.8	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.4	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.9	PID ATR PATHWAY	ATR signaling pathway
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.7	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.2	2.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.9	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	1.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	1.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	1.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	1.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	1.2	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	1.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	1.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.4	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)

Results for EZH2

Z-value: 1.39

Motif logo

Transcription factors associated with EZH2

Activity-expression correlation:

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: