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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXC1

Z-value: 0.73

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Transcription factors associated with FOXC1

Gene Symbol Gene ID Gene Info
FOXC1
ENSG00000054598.5 forkhead box C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXC1hg19_v2_chr6_+_1610681_1610681-0.345.1e-01Click!

Activity profile of FOXC1 motif

Sorted Z-values of FOXC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_72374948 0.91 ENST00000546307.1
ENST00000474509.1
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr12_-_106480587 0.75 ENST00000548902.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr17_-_57229155 0.55 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr16_-_88772670 0.47 ENST00000562544.1
RNF166
ring finger protein 166
chr8_-_71157595 0.46 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr4_-_103266626 0.42 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr14_-_89960395 0.41 ENST00000555034.1
ENST00000553904.1
FOXN3
forkhead box N3
chr11_-_104480019 0.40 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr17_-_37764128 0.40 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr3_-_57326704 0.38 ENST00000487349.1
ENST00000389601.3
ASB14
ankyrin repeat and SOCS box containing 14
chr22_-_50970566 0.38 ENST00000405135.1
ENST00000401779.1
ODF3B
outer dense fiber of sperm tails 3B
chr1_+_155099927 0.38 ENST00000368407.3
EFNA1
ephrin-A1
chr1_+_239882842 0.35 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr12_-_12714006 0.35 ENST00000541207.1
DUSP16
dual specificity phosphatase 16
chr20_-_62587735 0.31 ENST00000354216.6
ENST00000369892.3
ENST00000358711.3
UCKL1
uridine-cytidine kinase 1-like 1
chr22_-_50970506 0.30 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr6_-_10747802 0.29 ENST00000606522.1
ENST00000606652.1
RP11-421M1.8
RP11-421M1.8
chr5_+_136070614 0.28 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr12_-_122018114 0.27 ENST00000539394.1
KDM2B
lysine (K)-specific demethylase 2B
chr12_+_93115281 0.26 ENST00000549856.1
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr3_-_178865747 0.26 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr16_+_2570431 0.26 ENST00000563556.1
AMDHD2
amidohydrolase domain containing 2
chr17_+_79953310 0.25 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr8_-_95449155 0.25 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr12_-_12714025 0.24 ENST00000539940.1
DUSP16
dual specificity phosphatase 16
chr16_+_2570340 0.24 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2
amidohydrolase domain containing 2
chr2_+_12858355 0.24 ENST00000405331.3
TRIB2
tribbles pseudokinase 2
chr12_-_92539614 0.23 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr9_-_4299874 0.23 ENST00000381971.3
ENST00000477901.1
GLIS3
GLIS family zinc finger 3
chr2_+_85981008 0.22 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr1_+_25664408 0.22 ENST00000374358.4
TMEM50A
transmembrane protein 50A
chr17_+_7533439 0.21 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr10_+_71561649 0.21 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr11_-_8739383 0.21 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr15_+_63188009 0.21 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr2_+_181845532 0.20 ENST00000602475.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr2_+_173724771 0.19 ENST00000538974.1
ENST00000540783.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr10_+_71561630 0.19 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr3_+_38032216 0.19 ENST00000416303.1
VILL
villin-like
chr19_+_36024310 0.19 ENST00000222286.4
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr12_+_43086018 0.18 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr3_-_135916073 0.18 ENST00000481989.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr19_+_42806250 0.18 ENST00000598490.1
ENST00000341747.3
PRR19
proline rich 19
chr15_+_74911430 0.18 ENST00000562670.1
ENST00000564096.1
CLK3
CDC-like kinase 3
chr15_+_74509530 0.17 ENST00000321288.5
CCDC33
coiled-coil domain containing 33
chr5_+_159614374 0.17 ENST00000393980.4
FABP6
fatty acid binding protein 6, ileal
chrX_+_9935392 0.17 ENST00000445307.2
AC002365.1
Homo sapiens uncharacterized LOC100288814 (LOC100288814), mRNA.
chr3_-_127455200 0.17 ENST00000398101.3
MGLL
monoglyceride lipase
chr3_-_134092561 0.17 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chr4_+_124571409 0.17 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1
long intergenic non-protein coding RNA 1091
chr10_+_71562180 0.17 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr12_+_10365082 0.17 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr22_-_50970919 0.17 ENST00000329363.4
ENST00000437588.1
ODF3B
outer dense fiber of sperm tails 3B
chr8_-_19540086 0.16 ENST00000332246.6
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr19_-_13900972 0.16 ENST00000397557.1
AC008686.1
Uncharacterized protein
chr5_-_115872124 0.16 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr6_+_134274322 0.16 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr7_+_28452130 0.16 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr4_+_28437071 0.16 ENST00000509416.1
RP11-123O22.1
RP11-123O22.1
chr16_+_4666475 0.16 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr4_-_105416039 0.16 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr2_+_58655461 0.15 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr6_+_53794780 0.15 ENST00000505762.1
ENST00000511369.1
ENST00000431554.2
MLIP
RP11-411K7.1
muscular LMNA-interacting protein
RP11-411K7.1
chr1_+_234509186 0.15 ENST00000366615.4
COA6
cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)
chr12_+_59989918 0.15 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr3_-_129279894 0.15 ENST00000506979.1
PLXND1
plexin D1
chr7_-_72972319 0.15 ENST00000223368.2
BCL7B
B-cell CLL/lymphoma 7B
chr8_-_145754428 0.15 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr20_-_62582475 0.15 ENST00000369908.5
UCKL1
uridine-cytidine kinase 1-like 1
chr3_-_49131614 0.14 ENST00000450685.1
QRICH1
glutamine-rich 1
chr12_-_29936731 0.14 ENST00000552618.1
ENST00000539277.1
ENST00000551659.1
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr14_-_24020858 0.14 ENST00000419474.3
ZFHX2
zinc finger homeobox 2
chr2_-_72375167 0.14 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr7_-_86848933 0.14 ENST00000423734.1
TMEM243
transmembrane protein 243, mitochondrial
chr8_-_123793048 0.13 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr20_+_43990576 0.13 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr2_-_207078086 0.13 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr19_-_30199516 0.13 ENST00000591243.1
C19orf12
chromosome 19 open reading frame 12
chr17_-_39165366 0.13 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr12_+_93096759 0.13 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr6_+_34204642 0.12 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr19_+_3880581 0.12 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ATCAY
ataxia, cerebellar, Cayman type
chr9_-_136933615 0.12 ENST00000371834.2
BRD3
bromodomain containing 3
chr6_-_42016385 0.12 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr10_-_4285835 0.12 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr12_+_93096619 0.12 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr16_+_30064411 0.11 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr10_+_114710425 0.11 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr12_-_122018346 0.11 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr16_-_740419 0.11 ENST00000248142.6
WDR24
WD repeat domain 24
chr6_+_15401075 0.11 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr12_+_122516626 0.11 ENST00000319080.7
MLXIP
MLX interacting protein
chr8_-_23261589 0.11 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2
lysyl oxidase-like 2
chr8_+_104384616 0.10 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr3_-_193096600 0.10 ENST00000446087.1
ENST00000342358.4
ATP13A5
ATPase type 13A5
chr12_-_49453557 0.10 ENST00000547610.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr1_-_153931052 0.10 ENST00000368630.3
ENST00000368633.1
CRTC2
CREB regulated transcription coactivator 2
chr5_+_150040403 0.10 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr15_+_42120283 0.10 ENST00000542534.2
ENST00000397299.4
ENST00000408047.1
ENST00000431823.1
ENST00000382448.4
ENST00000342159.4
PLA2G4B
JMJD7
JMJD7-PLA2G4B
phospholipase A2, group IVB (cytosolic)
jumonji domain containing 7
JMJD7-PLA2G4B readthrough
chr16_+_30064444 0.10 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA
aldolase A, fructose-bisphosphate
chr6_-_5260963 0.10 ENST00000464010.1
ENST00000468929.1
ENST00000480566.1
LYRM4
LYR motif containing 4
chr6_+_134274354 0.10 ENST00000367869.1
TBPL1
TBP-like 1
chr17_-_46688334 0.10 ENST00000239165.7
HOXB7
homeobox B7
chr16_-_740354 0.10 ENST00000293883.4
WDR24
WD repeat domain 24
chr17_+_41363854 0.10 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chrX_-_19688475 0.10 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr16_-_21875424 0.10 ENST00000541674.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr2_-_207078154 0.09 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr2_+_162272605 0.09 ENST00000389554.3
TBR1
T-box, brain, 1
chr17_+_9745786 0.09 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr16_+_22517166 0.09 ENST00000356156.3
NPIPB5
nuclear pore complex interacting protein family, member B5
chr4_+_76871883 0.09 ENST00000599764.1
AC110615.1
Uncharacterized protein
chr2_+_96257766 0.09 ENST00000272395.2
TRIM43
tripartite motif containing 43
chr2_-_224467002 0.09 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr21_+_17792672 0.08 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr19_+_782755 0.08 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr1_-_246729544 0.08 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr5_-_39425222 0.08 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr3_+_40351169 0.08 ENST00000232905.3
EIF1B
eukaryotic translation initiation factor 1B
chr5_-_39425290 0.08 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr6_-_39399087 0.08 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
KIF6
kinesin family member 6
chr16_+_8715536 0.08 ENST00000563958.1
ENST00000381920.3
ENST00000564554.1
METTL22
methyltransferase like 22
chr7_+_80231466 0.08 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr2_+_105050794 0.08 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr3_-_71632894 0.08 ENST00000493089.1
FOXP1
forkhead box P1
chr2_+_113885138 0.08 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr18_+_32073253 0.08 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chrX_+_9431324 0.08 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr1_+_199996702 0.08 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr6_+_18387570 0.08 ENST00000259939.3
RNF144B
ring finger protein 144B
chr3_-_16524357 0.07 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr10_+_71561704 0.07 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr9_-_89562104 0.07 ENST00000298743.7
GAS1
growth arrest-specific 1
chr1_-_94079648 0.07 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr5_-_146302078 0.07 ENST00000508545.2
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr15_-_76352069 0.07 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr2_+_66918558 0.07 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr6_+_10748019 0.07 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
SYCP2L
TMEM14B
synaptonemal complex protein 2-like
transmembrane protein 14B
chr5_+_40841410 0.07 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr4_-_186696636 0.07 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_214013353 0.07 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKZF2
IKAROS family zinc finger 2 (Helios)
chr3_+_189349162 0.07 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr14_+_23340822 0.07 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr12_-_116714564 0.07 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr19_-_40919271 0.07 ENST00000291825.7
ENST00000324001.7
PRX
periaxin
chr14_+_69726864 0.06 ENST00000448469.3
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr16_+_8715574 0.06 ENST00000561758.1
METTL22
methyltransferase like 22
chr7_+_79998864 0.06 ENST00000435819.1
CD36
CD36 molecule (thrombospondin receptor)
chr17_+_17685422 0.06 ENST00000395774.1
RAI1
retinoic acid induced 1
chr7_+_139529085 0.06 ENST00000539806.1
TBXAS1
thromboxane A synthase 1 (platelet)
chrX_+_135730373 0.06 ENST00000370628.2
CD40LG
CD40 ligand
chr3_-_11623804 0.06 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr1_+_73771844 0.06 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
RP4-598G3.1
chr5_+_166711804 0.06 ENST00000518659.1
ENST00000545108.1
TENM2
teneurin transmembrane protein 2
chr1_+_56046710 0.06 ENST00000422374.1
RP11-466L17.1
RP11-466L17.1
chr9_+_103340354 0.06 ENST00000307584.5
MURC
muscle-related coiled-coil protein
chr4_-_83483360 0.06 ENST00000449862.2
TMEM150C
transmembrane protein 150C
chr2_+_173792893 0.06 ENST00000535187.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr16_-_4817129 0.06 ENST00000545009.1
ENST00000219478.6
ZNF500
zinc finger protein 500
chr5_-_115872142 0.06 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr14_+_38033252 0.06 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chrX_+_135730297 0.05 ENST00000370629.2
CD40LG
CD40 ligand
chr10_+_114710211 0.05 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr3_-_187454281 0.05 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr15_+_67418047 0.05 ENST00000540846.2
SMAD3
SMAD family member 3
chr1_+_150122034 0.05 ENST00000025469.6
ENST00000369124.4
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr1_+_43855560 0.05 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr5_-_39425068 0.05 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr11_-_126870655 0.05 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr12_-_49333446 0.05 ENST00000537495.1
AC073610.5
Uncharacterized protein
chr4_+_57276661 0.05 ENST00000598320.1
AC068620.1
Uncharacterized protein
chr1_+_22778337 0.05 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr20_-_22566089 0.05 ENST00000377115.4
FOXA2
forkhead box A2
chr11_-_92930556 0.05 ENST00000529184.1
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr2_-_190044480 0.05 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr19_-_52255107 0.05 ENST00000595042.1
ENST00000304748.4
FPR1
formyl peptide receptor 1
chr3_-_49131788 0.05 ENST00000395443.2
ENST00000411682.1
QRICH1
glutamine-rich 1
chr1_+_61547894 0.05 ENST00000403491.3
NFIA
nuclear factor I/A
chr8_+_120079478 0.05 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr8_-_93107443 0.05 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_131438443 0.05 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr7_+_136553370 0.04 ENST00000445907.2
CHRM2
cholinergic receptor, muscarinic 2
chrX_-_19689106 0.04 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr1_-_94312706 0.04 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chrY_+_59100480 0.04 ENSTR0000302805.2
SPRY3
sprouty homolog 3 (Drosophila)
chr10_-_118032697 0.04 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr22_-_38699003 0.04 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chr10_+_69869237 0.04 ENST00000373675.3
MYPN
myopalladin
chr5_+_176692466 0.04 ENST00000508029.1
ENST00000503056.1
NSD1
nuclear receptor binding SET domain protein 1
chr5_+_95385819 0.04 ENST00000507997.1
RP11-254I22.1
RP11-254I22.1
chr22_+_24828087 0.04 ENST00000472248.1
ENST00000436735.1
ADORA2A
adenosine A2a receptor
chr1_+_246729724 0.04 ENST00000366513.4
ENST00000366512.3
CNST
consortin, connexin sorting protein
chr17_+_28268623 0.04 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5
EF-hand calcium binding domain 5
chr21_-_34186006 0.04 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr3_+_114012819 0.04 ENST00000383671.3
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr6_+_10747986 0.04 ENST00000379542.5
TMEM14B
transmembrane protein 14B
chr12_+_54378849 0.04 ENST00000515593.1
HOXC10
homeobox C10
chr7_-_27219632 0.04 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr11_+_93479588 0.04 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr14_+_76776957 0.04 ENST00000512784.1
ESRRB
estrogen-related receptor beta

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 0.5 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.6 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.4 GO:0014028 notochord formation(GO:0014028)
0.1 0.2 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.5 GO:0044211 CTP salvage(GO:0044211)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.4 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.3 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.0 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.0 GO:0090381 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of mesodermal cell fate specification(GO:0042662) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.0 GO:0045013 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0048625 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.5 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.1 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts