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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXD3_FOXI1_FOXF1

Z-value: 1.18

Motif logo

Transcription factors associated with FOXD3_FOXI1_FOXF1

Gene Symbol Gene ID Gene Info
ENSG00000187140.4 forkhead box D3
ENSG00000168269.7 forkhead box I1
ENSG00000103241.5 forkhead box F1

Activity profile of FOXD3_FOXI1_FOXF1 motif

Sorted Z-values of FOXD3_FOXI1_FOXF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_24645078 1.38 ENST00000264463.4
cadherin 10, type 2 (T2-cadherin)
chr4_+_75174180 1.05 ENST00000413830.1
epithelial mitogen
chr4_-_153303658 0.87 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_+_102200948 0.78 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
peptidylglycine alpha-amidating monooxygenase
chr3_+_178865887 0.72 ENST00000477735.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr13_-_86373536 0.70 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr21_+_17791648 0.64 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
long intergenic non-protein coding RNA 478
chr12_+_25348186 0.64 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYR motif containing 5
chr2_-_188312971 0.60 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
calcitonin receptor-like
chr15_+_76352178 0.59 ENST00000388942.3
chromosome 15 open reading frame 27
chr11_+_27076764 0.55 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr2_-_111291587 0.55 ENST00000437167.1
RANBP2-like and GRIP domain containing 6
chr8_+_97597148 0.55 ENST00000521590.1
syndecan 2
chr12_+_51318513 0.53 ENST00000332160.4
methyltransferase like 7A
chr3_+_177159744 0.52 ENST00000439009.1
long intergenic non-protein coding RNA 578
chr9_-_3469181 0.52 ENST00000366116.2
Uncharacterized protein
chr14_-_36990061 0.52 ENST00000546983.1
NK2 homeobox 1
chr2_-_152146385 0.51 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr1_+_184020830 0.51 ENST00000533373.1
ENST00000423085.2
TSEN15 tRNA splicing endonuclease subunit
chr4_-_99578776 0.50 ENST00000515287.1
tetraspanin 5
chr2_-_178129551 0.50 ENST00000430047.1
nuclear factor, erythroid 2-like 2
chr2_+_232575168 0.48 ENST00000440384.1
prothymosin, alpha
chr3_-_195310802 0.48 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr15_+_96869165 0.48 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chr7_+_106415457 0.46 ENST00000490162.2
ENST00000470135.1
RP5-884M6.1
chrX_+_22050546 0.46 ENST00000379374.4
phosphate regulating endopeptidase homolog, X-linked
chr14_-_54418598 0.46 ENST00000609748.1
ENST00000558961.1
bone morphogenetic protein 4
chr1_+_184020811 0.45 ENST00000361641.1
TSEN15 tRNA splicing endonuclease subunit
chr4_-_140544386 0.45 ENST00000561977.1
RP11-308D13.3
chr5_-_142065612 0.45 ENST00000360966.5
ENST00000411960.1
fibroblast growth factor 1 (acidic)
chr13_-_40924439 0.44 ENST00000400432.3
RP11-172E9.2
chr1_+_95616933 0.43 ENST00000604203.1
TMEM56-RWDD3 readthrough
chr7_+_129906660 0.43 ENST00000222481.4
carboxypeptidase A2 (pancreatic)
chr10_-_98031310 0.42 ENST00000427367.2
ENST00000413476.2
B-cell linker
chr8_+_79428539 0.41 ENST00000352966.5
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr5_-_111091948 0.41 ENST00000447165.2
neuronal regeneration related protein
chr3_-_168864315 0.41 ENST00000475754.1
ENST00000484519.1
MDS1 and EVI1 complex locus
chr17_+_4692230 0.40 ENST00000331264.7
glycolipid transfer protein domain containing 2
chr8_-_95449155 0.40 ENST00000481490.2
fibrinogen silencer binding protein
chr17_+_72426891 0.39 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr10_-_98031265 0.39 ENST00000224337.5
ENST00000371176.2
B-cell linker
chr1_-_57431679 0.38 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
complement component 8, beta polypeptide
chr9_-_99064386 0.38 ENST00000375262.2
hydroxysteroid (17-beta) dehydrogenase 3
chr11_-_111781554 0.38 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr2_+_28974489 0.37 ENST00000455580.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr2_-_166702601 0.37 ENST00000428888.1
AC009495.4
chr11_+_63304273 0.36 ENST00000439013.2
ENST00000255688.3
retinoic acid receptor responder (tazarotene induced) 3
chr1_+_164528866 0.36 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr15_+_96904487 0.35 ENST00000600790.1
Uncharacterized protein
chr3_-_178865747 0.34 ENST00000435560.1
RP11-360P21.2
chr12_+_25348139 0.33 ENST00000557540.2
ENST00000381356.4
LYR motif containing 5
chrX_+_105936982 0.33 ENST00000418562.1
ring finger protein 128, E3 ubiquitin protein ligase
chr2_+_171640291 0.33 ENST00000409885.1
glutamate-rich 2
chr9_-_100000957 0.33 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
chr12_+_80838126 0.32 ENST00000266688.5
protein tyrosine phosphatase, receptor type, Q
chr8_+_52730143 0.32 ENST00000415643.1
Uncharacterized protein
chr5_-_142077569 0.32 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
fibroblast growth factor 1 (acidic)
chr15_-_76352069 0.32 ENST00000305435.10
ENST00000563910.1
neuregulin 4
chr11_+_65657875 0.32 ENST00000312579.2
coiled-coil domain containing 85B
chr14_+_76776957 0.31 ENST00000512784.1
estrogen-related receptor beta
chrX_+_153769446 0.31 ENST00000422680.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr9_-_99064429 0.31 ENST00000375263.3
hydroxysteroid (17-beta) dehydrogenase 3
chr11_+_113930955 0.31 ENST00000535700.1
zinc finger and BTB domain containing 16
chr17_-_40215075 0.31 ENST00000436535.3
zinc finger protein 385C
chr3_-_168864427 0.31 ENST00000468789.1
MDS1 and EVI1 complex locus
chr13_+_97928395 0.30 ENST00000445661.2
muscleblind-like splicing regulator 2
chr11_-_108464321 0.30 ENST00000265843.4
exophilin 5
chr2_-_202222091 0.30 ENST00000405148.2
ENST00000392257.3
ENST00000439709.1
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12
chr1_+_164529004 0.30 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
pre-B-cell leukemia homeobox 1
chr4_+_165675269 0.30 ENST00000507311.1
RP11-294O2.2
chr11_+_17316870 0.30 ENST00000458064.2
nucleobindin 2
chr11_-_46639436 0.30 ENST00000532281.1
harbinger transposase derived 1
chr1_+_12524965 0.30 ENST00000471923.1
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr12_+_28605426 0.29 ENST00000542801.1
coiled-coil domain containing 91
chr13_-_36050819 0.29 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr1_-_57045228 0.28 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr9_+_26956371 0.27 ENST00000380062.5
ENST00000518614.1
intraflagellar transport 74 homolog (Chlamydomonas)
chr6_+_53794780 0.27 ENST00000505762.1
ENST00000511369.1
ENST00000431554.2
muscular LMNA-interacting protein
RP11-411K7.1
chr15_-_38519066 0.27 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
chr9_-_39239171 0.27 ENST00000358144.2
contactin associated protein-like 3
chr2_-_207078154 0.26 ENST00000447845.1
G protein-coupled receptor 1
chr4_-_147442817 0.26 ENST00000507030.1
solute carrier family 10, member 7
chr17_+_67498396 0.26 ENST00000588110.1
mitogen-activated protein kinase kinase 6
chr7_+_116654958 0.26 ENST00000449366.1
suppression of tumorigenicity 7
chr17_-_36358166 0.26 ENST00000537432.1
TBC1 domain family, member 3
chr2_+_191208791 0.26 ENST00000423767.1
ENST00000451089.1
inositol polyphosphate-1-phosphatase
chr4_-_99850243 0.26 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr13_+_52598827 0.25 ENST00000521776.2
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr1_-_101360331 0.25 ENST00000416479.1
ENST00000370113.3
exostosin-like glycosyltransferase 2
chr5_+_68665608 0.25 ENST00000509734.1
ENST00000354868.5
ENST00000521422.1
ENST00000354312.3
ENST00000345306.6
RAD17 homolog (S. pombe)
chr4_+_184365744 0.25 ENST00000504169.1
ENST00000302350.4
CDKN2A interacting protein
chr1_+_117963209 0.25 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr11_-_111781610 0.25 ENST00000525823.1
crystallin, alpha B
chr2_-_165698662 0.24 ENST00000194871.6
ENST00000445474.2
cordon-bleu WH2 repeat protein-like 1
chr4_+_166794383 0.24 ENST00000061240.2
ENST00000507499.1
tolloid-like 1
chr6_-_134861089 0.24 ENST00000606039.1
RP11-557H15.4
chr10_-_61122220 0.24 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
family with sequence similarity 13, member C
chr2_+_181988620 0.24 ENST00000428474.1
ENST00000424655.1
AC104820.2
chr14_+_51026926 0.24 ENST00000557735.1
atlastin GTPase 1
chr9_+_108006880 0.24 ENST00000374723.1
ENST00000374720.3
ENST00000374724.1
solute carrier family 44 (choline transporter), member 1
chr1_+_2258581 0.24 ENST00000600779.1
Uncharacterized protein
chr11_+_114549108 0.24 ENST00000389586.4
ENST00000375475.5
neurexophilin and PC-esterase domain family, member 2
chr2_-_211341411 0.23 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr8_-_72274467 0.23 ENST00000340726.3
eyes absent homolog 1 (Drosophila)
chr2_-_106054952 0.23 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
four and a half LIM domains 2
chr4_-_74486109 0.23 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6
chr17_-_77967433 0.23 ENST00000571872.1
TBC1 domain family, member 16
chr7_+_23637763 0.23 ENST00000410069.1
coiled-coil domain containing 126
chr10_-_4720333 0.23 ENST00000430998.2
long intergenic non-protein coding RNA 704
chr1_-_8000872 0.23 ENST00000377507.3
tumor necrosis factor receptor superfamily, member 9
chr5_-_42811986 0.22 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr1_+_239882842 0.22 ENST00000448020.1
cholinergic receptor, muscarinic 3
chr3_+_178866199 0.22 ENST00000263967.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr18_-_25616519 0.22 ENST00000399380.3
cadherin 2, type 1, N-cadherin (neuronal)
chr9_+_42671887 0.22 ENST00000456520.1
ENST00000377391.3
COBW domain containing 7
chr8_+_74903580 0.22 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chr5_+_147691979 0.22 ENST00000274565.4
serine peptidase inhibitor, Kazal type 7 (putative)
chr12_-_15865844 0.22 ENST00000543612.1
epidermal growth factor receptor pathway substrate 8
chr8_-_90993869 0.22 ENST00000517772.1
nibrin
chr20_+_9049742 0.22 ENST00000437503.1
phospholipase C, beta 4
chr7_+_116451100 0.22 ENST00000464223.1
ENST00000484325.1
capping protein (actin filament) muscle Z-line, alpha 2
chr11_-_111781454 0.22 ENST00000533280.1
crystallin, alpha B
chr15_-_59041768 0.22 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM metallopeptidase domain 10
chrX_+_24483338 0.22 ENST00000379162.4
ENST00000441463.2
pyruvate dehydrogenase kinase, isozyme 3
chr4_-_87028478 0.22 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr9_+_109685630 0.22 ENST00000451160.2
Uncharacterized protein
chr7_+_134551583 0.21 ENST00000435928.1
caldesmon 1
chr4_-_175443484 0.21 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr5_+_42756903 0.21 ENST00000361970.5
ENST00000388827.4
coiled-coil domain containing 152
chr4_+_103790462 0.21 ENST00000503643.1
CDGSH iron sulfur domain 2
chr16_-_46649905 0.21 ENST00000569702.1
SHC SH2-domain binding protein 1
chr6_-_56492816 0.21 ENST00000522360.1
dystonin
chr5_-_142782862 0.21 ENST00000415690.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr22_+_40440804 0.21 ENST00000441751.1
ENST00000301923.9
trinucleotide repeat containing 6B
chr15_+_38964048 0.21 ENST00000560203.1
ENST00000557946.1
RP11-275I4.2
chr14_+_51026844 0.20 ENST00000554886.1
atlastin GTPase 1
chr11_-_62323702 0.20 ENST00000530285.1
AHNAK nucleoprotein
chrX_-_41449204 0.20 ENST00000378179.3
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr4_+_129732419 0.20 ENST00000510308.1
jade family PHD finger 1
chr4_+_169013666 0.20 ENST00000359299.3
annexin A10
chr9_+_71986182 0.20 ENST00000303068.7
family with sequence similarity 189, member A2
chr7_+_121513374 0.20 ENST00000449182.1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr8_+_86999516 0.20 ENST00000521564.1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr9_+_67977438 0.20 ENST00000456982.1
Protein LOC644249
chr3_+_46449049 0.20 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
chemokine (C-C motif) receptor-like 2
chr12_-_68696652 0.20 ENST00000539972.1
Mdm1 nuclear protein homolog (mouse)
chr11_+_27062272 0.20 ENST00000529202.1
ENST00000533566.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr12_-_102591604 0.20 ENST00000329406.4
pro-melanin-concentrating hormone
chr22_+_46449674 0.20 ENST00000381051.2
hsa-mir-4763
chr10_+_112631699 0.20 ENST00000444997.1
programmed cell death 4 (neoplastic transformation inhibitor)
chr15_-_52944231 0.20 ENST00000546305.2
family with sequence similarity 214, member A
chr11_-_112034803 0.20 ENST00000528832.1
interleukin 18 (interferon-gamma-inducing factor)
chr16_-_67260691 0.20 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
leucine rich repeat containing 29
chr2_-_188419078 0.20 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr3_-_186857267 0.19 ENST00000455270.1
ENST00000296277.4
ribosomal protein L39-like
chr6_-_56716686 0.19 ENST00000520645.1
dystonin
chr1_-_150669500 0.19 ENST00000271732.3
golgi phosphoprotein 3-like
chr7_+_77469439 0.19 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr9_+_26956474 0.19 ENST00000429045.2
intraflagellar transport 74 homolog (Chlamydomonas)
chr14_+_56127989 0.19 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr9_+_131062367 0.19 ENST00000601297.1
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr4_+_165675197 0.19 ENST00000515485.1
RP11-294O2.2
chr6_+_89790490 0.19 ENST00000336032.3
proline-rich nuclear receptor coactivator 1
chr7_+_151791095 0.19 ENST00000422997.2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr12_+_21207503 0.19 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr1_-_109935819 0.19 ENST00000538502.1
sortilin 1
chr12_+_72061563 0.19 ENST00000551238.1
THAP domain containing, apoptosis associated protein 2
chr4_-_147443043 0.19 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
solute carrier family 10, member 7
chr13_-_33002151 0.19 ENST00000495479.1
ENST00000343281.4
ENST00000464470.1
ENST00000380139.4
ENST00000380133.2
NEDD4 binding protein 2-like 1
chr1_+_47264711 0.18 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
cytochrome P450, family 4, subfamily B, polypeptide 1
chr10_+_112631547 0.18 ENST00000280154.7
ENST00000393104.2
programmed cell death 4 (neoplastic transformation inhibitor)
chr12_-_79849240 0.18 ENST00000550268.1
RP1-78O14.1
chr6_-_88001706 0.18 ENST00000369576.2
gap junction protein, beta 7, 25kDa
chr4_+_95174445 0.18 ENST00000509418.1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr5_+_81601166 0.18 ENST00000439350.1
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr19_-_39402798 0.18 ENST00000571838.1
coiled-coil glutamate-rich protein 2
chr3_+_119316721 0.18 ENST00000488919.1
ENST00000495992.1
phospholipase A1 member A
chr10_-_4720301 0.18 ENST00000449712.1
long intergenic non-protein coding RNA 704
chr1_-_89664595 0.18 ENST00000355754.6
guanylate binding protein 4
chr6_+_47666275 0.18 ENST00000327753.3
ENST00000283303.2
G protein-coupled receptor 115
chr9_-_86432547 0.18 ENST00000376365.3
ENST00000376371.2
G kinase anchoring protein 1
chr15_-_55790515 0.18 ENST00000448430.2
ENST00000457155.2
dyslexia susceptibility 1 candidate 1
chr6_+_45296391 0.18 ENST00000371436.6
ENST00000576263.1
runt-related transcription factor 2
chr14_+_73563735 0.18 ENST00000532192.1
RNA binding motif protein 25
chr8_-_72274355 0.18 ENST00000388741.2
eyes absent homolog 1 (Drosophila)
chr5_-_149465990 0.18 ENST00000543093.1
colony stimulating factor 1 receptor
chrX_+_22056165 0.18 ENST00000535894.1
phosphate regulating endopeptidase homolog, X-linked
chr9_-_127710292 0.18 ENST00000421514.1
golgin A1
chr5_+_139027877 0.18 ENST00000302517.3
CXXC finger protein 5
chr11_-_108464465 0.18 ENST00000525344.1
exophilin 5
chr4_-_15683230 0.18 ENST00000515679.1
F-box and leucine-rich repeat protein 5
chr14_+_45464658 0.18 ENST00000555874.1
family with sequence similarity 179, member B
chr17_-_74547256 0.18 ENST00000589145.1
cytoglobin
chr1_-_156269428 0.18 ENST00000339922.3
von Hippel-Lindau tumor suppressor-like
chr3_-_12200851 0.17 ENST00000287814.4
TIMP metallopeptidase inhibitor 4
chr18_-_53070913 0.17 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr7_-_84122033 0.17 ENST00000424555.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_78470530 0.17 ENST00000370763.5
DnaJ (Hsp40) homolog, subfamily B, member 4
chr3_-_121448791 0.17 ENST00000489400.1
golgin B1
chr20_+_9049682 0.17 ENST00000334005.3
ENST00000378473.3
phospholipase C, beta 4

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD3_FOXI1_FOXF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 1.0 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.8 GO:0018032 protein amidation(GO:0018032)
0.1 0.4 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.5 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.1 0.5 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.1 0.5 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.7 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.7 GO:0008218 bioluminescence(GO:0008218)
0.1 0.6 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.5 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 0.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.7 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 1.4 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.1 0.6 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 1.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.6 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.2 GO:1905205 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.7 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.6 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 1.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.0 0.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 1.1 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.1 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.8 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.0 GO:0001934 positive regulation of protein phosphorylation(GO:0001934)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:1902571 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0002765 negative regulation of type IV hypersensitivity(GO:0001808) immune response-inhibiting signal transduction(GO:0002765)
0.0 0.0 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.0 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.1 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.7 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.0 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:1904647 response to rotenone(GO:1904647)
0.0 0.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.0 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
0.0 0.0 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0010165 response to X-ray(GO:0010165)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.0 GO:0044359 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0006997 nucleus organization(GO:0006997)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.4 GO:0072534 perineuronal net(GO:0072534)
0.1 0.9 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0043293 apoptosome(GO:0043293)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.0 GO:1990923 PET complex(GO:1990923)
0.0 0.2 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.0 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.6 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 1.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.8 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 1.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.4 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.7 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.5 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.2 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.4 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.3 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.3 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.7 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0019887 protein kinase inhibitor activity(GO:0004860) kinase regulator activity(GO:0019207) kinase inhibitor activity(GO:0019210) protein kinase regulator activity(GO:0019887)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.0 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 1.4 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling