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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXL1

Z-value: 0.79

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Transcription factors associated with FOXL1

Gene Symbol Gene ID Gene Info
FOXL1
ENSG00000176678.4 forkhead box L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXL1hg19_v2_chr16_+_86612112_866121230.814.9e-02Click!

Activity profile of FOXL1 motif

Sorted Z-values of FOXL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_181988620 0.82 ENST00000428474.1
ENST00000424655.1
AC104820.2
AC104820.2
chr6_+_71104588 0.66 ENST00000418403.1
RP11-462G2.1
RP11-462G2.1
chr8_-_82598067 0.63 ENST00000523942.1
ENST00000522997.1
IMPA1
inositol(myo)-1(or 4)-monophosphatase 1
chr1_+_160709055 0.62 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7
SLAM family member 7
chr12_-_10601963 0.61 ENST00000543893.1
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr4_-_100356551 0.56 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_-_104916034 0.54 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr1_+_95616933 0.52 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr11_-_59633951 0.51 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr1_+_104615595 0.45 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chr19_-_44384291 0.44 ENST00000324394.6
ZNF404
zinc finger protein 404
chr14_+_73563735 0.42 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr7_+_116654958 0.41 ENST00000449366.1
ST7
suppression of tumorigenicity 7
chr9_-_95055923 0.39 ENST00000430417.1
IARS
isoleucyl-tRNA synthetase
chr4_-_112993808 0.39 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr2_+_114163945 0.36 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr18_+_158327 0.36 ENST00000582707.1
USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr9_+_67968793 0.35 ENST00000417488.1
RP11-195B21.3
Protein LOC644249
chr6_+_63921351 0.35 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr4_-_100356291 0.35 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr13_+_20268547 0.34 ENST00000601204.1
AL354808.2
AL354808.2
chr15_-_83224682 0.33 ENST00000562833.1
RP11-152F13.10
RP11-152F13.10
chr1_+_174670143 0.32 ENST00000367687.1
ENST00000347255.2
RABGAP1L
RAB GTPase activating protein 1-like
chr22_-_29107919 0.32 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr9_-_99064386 0.32 ENST00000375262.2
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr1_+_219347203 0.31 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr20_-_14318248 0.31 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr21_+_35107346 0.31 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr22_-_18923655 0.30 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
PRODH
proline dehydrogenase (oxidase) 1
chrX_-_117119243 0.30 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr10_-_98031265 0.30 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr1_-_186365908 0.30 ENST00000598663.1
AL596220.1
Uncharacterized protein
chr7_+_33168856 0.29 ENST00000432983.1
BBS9
Bardet-Biedl syndrome 9
chr11_-_18062335 0.29 ENST00000341556.2
TPH1
tryptophan hydroxylase 1
chr7_+_6121296 0.29 ENST00000428901.1
AC004895.4
AC004895.4
chr9_-_21482312 0.28 ENST00000448696.3
IFNE
interferon, epsilon
chr19_+_9203855 0.28 ENST00000429566.3
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr4_+_78829479 0.28 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr20_+_12989895 0.28 ENST00000450297.1
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr12_+_21207503 0.27 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr2_+_145780767 0.27 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr3_-_93747425 0.27 ENST00000315099.2
STX19
syntaxin 19
chr4_-_100356844 0.27 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_76076793 0.27 ENST00000370859.3
SLC44A5
solute carrier family 44, member 5
chr13_+_53030107 0.27 ENST00000490903.1
ENST00000480747.1
CKAP2
cytoskeleton associated protein 2
chr6_-_56492816 0.27 ENST00000522360.1
DST
dystonin
chr12_+_69742121 0.27 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr1_+_85527987 0.27 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr4_+_74301880 0.27 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr16_-_3422283 0.27 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr4_+_146402346 0.26 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr5_+_147691979 0.26 ENST00000274565.4
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr6_+_127898312 0.25 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr13_-_86373536 0.25 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr9_-_47314222 0.25 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
AL953854.2
chr4_-_76008706 0.24 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5
RP11-44F21.5
chr1_-_115301235 0.24 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr1_+_89829610 0.24 ENST00000370456.4
ENST00000535065.1
GBP6
guanylate binding protein family, member 6
chr1_-_145382362 0.23 ENST00000419817.1
ENST00000421937.3
ENST00000433081.2
RP11-458D21.1
RP11-458D21.1
chr1_+_219347186 0.23 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr1_+_78470530 0.23 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr5_+_115420688 0.23 ENST00000274458.4
COMMD10
COMM domain containing 10
chr12_+_28605426 0.23 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr2_-_55237484 0.23 ENST00000394609.2
RTN4
reticulon 4
chr2_+_190722119 0.23 ENST00000452382.1
PMS1
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
chr1_-_247171347 0.23 ENST00000339986.7
ENST00000487338.2
ZNF695
zinc finger protein 695
chr7_-_56119156 0.23 ENST00000421312.1
ENST00000416592.1
PSPH
phosphoserine phosphatase
chr15_+_69373210 0.22 ENST00000435479.1
ENST00000559870.1
LINC00277
RP11-809H16.5
long intergenic non-protein coding RNA 277
RP11-809H16.5
chr10_+_118349920 0.22 ENST00000531984.1
PNLIPRP1
pancreatic lipase-related protein 1
chr11_+_27015628 0.22 ENST00000318627.2
FIBIN
fin bud initiation factor homolog (zebrafish)
chr14_+_50291993 0.22 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr17_-_59668550 0.22 ENST00000521764.1
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr10_+_5238793 0.22 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr4_-_87515202 0.21 ENST00000502302.1
ENST00000513186.1
MAPK10
mitogen-activated protein kinase 10
chr4_+_165675269 0.21 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr6_-_26189304 0.21 ENST00000340756.2
HIST1H4D
histone cluster 1, H4d
chr13_-_38172863 0.21 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr2_+_187371440 0.21 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr7_-_105221898 0.21 ENST00000486180.1
ENST00000485614.1
ENST00000480514.1
EFCAB10
EF-hand calcium binding domain 10
chr3_+_186742464 0.21 ENST00000416235.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr9_+_135937365 0.21 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr3_-_165555200 0.21 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr5_-_42887494 0.21 ENST00000514218.1
SEPP1
selenoprotein P, plasma, 1
chr4_+_178230985 0.21 ENST00000264596.3
NEIL3
nei endonuclease VIII-like 3 (E. coli)
chr6_-_20212630 0.20 ENST00000324607.7
ENST00000541730.1
ENST00000536798.1
MBOAT1
membrane bound O-acyltransferase domain containing 1
chr2_-_176867534 0.20 ENST00000445472.1
KIAA1715
KIAA1715
chr5_+_39105358 0.20 ENST00000593965.1
AC008964.1
AC008964.1
chr9_-_27005686 0.20 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr9_-_127710292 0.20 ENST00000421514.1
GOLGA1
golgin A1
chr2_+_183989157 0.20 ENST00000541912.1
NUP35
nucleoporin 35kDa
chr21_+_25801041 0.20 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr15_-_54267147 0.20 ENST00000558866.1
ENST00000558920.1
RP11-643A5.2
RP11-643A5.2
chr12_-_79849240 0.20 ENST00000550268.1
RP1-78O14.1
RP1-78O14.1
chr7_+_64126535 0.20 ENST00000344930.3
ZNF107
zinc finger protein 107
chr4_-_84035905 0.20 ENST00000311507.4
PLAC8
placenta-specific 8
chr1_+_84630053 0.20 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_149459549 0.20 ENST00000369175.3
FAM72C
family with sequence similarity 72, member C
chr15_+_63414760 0.19 ENST00000557972.1
LACTB
lactamase, beta
chr3_-_100551141 0.19 ENST00000478235.1
ENST00000471901.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr1_+_117963209 0.19 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr1_+_160709076 0.19 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7
chr12_-_68696652 0.19 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr10_-_98031310 0.19 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr3_+_161214596 0.19 ENST00000327928.4
OTOL1
otolin 1
chr12_+_133614062 0.19 ENST00000540031.1
ENST00000536123.1
ZNF84
zinc finger protein 84
chr2_+_183982255 0.19 ENST00000455063.1
NUP35
nucleoporin 35kDa
chr7_+_12726474 0.19 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ARL4A
ADP-ribosylation factor-like 4A
chr2_+_109403193 0.19 ENST00000412964.2
ENST00000295124.4
CCDC138
coiled-coil domain containing 138
chr1_-_113615699 0.19 ENST00000421157.1
RP11-31F15.2
RP11-31F15.2
chrX_+_37865804 0.18 ENST00000297875.2
ENST00000357972.5
SYTL5
synaptotagmin-like 5
chr2_+_54342574 0.18 ENST00000303536.4
ENST00000394666.3
ACYP2
acylphosphatase 2, muscle type
chr2_+_29353520 0.18 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr2_-_188419078 0.18 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr8_+_104831472 0.18 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr1_+_156308403 0.18 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chr15_+_49913201 0.18 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
DTWD1
DTW domain containing 1
chr11_-_26593677 0.18 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr7_-_112430647 0.18 ENST00000312814.6
TMEM168
transmembrane protein 168
chr9_-_69229650 0.18 ENST00000416428.1
CBWD6
COBW domain containing 6
chr4_+_76871883 0.17 ENST00000599764.1
AC110615.1
Uncharacterized protein
chr18_+_61445205 0.17 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr13_+_37581115 0.17 ENST00000481013.1
EXOSC8
exosome component 8
chrX_+_102192200 0.17 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chr6_-_113953705 0.17 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr7_-_83278322 0.17 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr12_+_133757995 0.17 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
ZNF268
zinc finger protein 268
chr6_-_41006928 0.17 ENST00000244565.3
UNC5CL
unc-5 homolog C (C. elegans)-like
chr9_-_39239171 0.17 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr14_+_57671888 0.17 ENST00000391612.1
AL391152.1
AL391152.1
chr11_-_104972158 0.17 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr1_-_145382434 0.17 ENST00000610154.1
RP11-458D21.1
RP11-458D21.1
chr3_-_155524049 0.17 ENST00000534941.1
ENST00000340171.2
C3orf33
chromosome 3 open reading frame 33
chr4_-_14889791 0.16 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr6_-_135271219 0.16 ENST00000367847.2
ENST00000367845.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chrX_-_138790348 0.16 ENST00000414978.1
ENST00000519895.1
MCF2
MCF.2 cell line derived transforming sequence
chr4_+_41540160 0.16 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr5_+_68860949 0.16 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr9_+_123884038 0.16 ENST00000373847.1
CNTRL
centriolin
chr6_+_106988986 0.16 ENST00000457437.1
ENST00000535438.1
AIM1
absent in melanoma 1
chr4_+_113066552 0.16 ENST00000309733.5
C4orf32
chromosome 4 open reading frame 32
chr1_+_84630574 0.16 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_+_94451574 0.16 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr11_-_112034831 0.16 ENST00000280357.7
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr1_-_59012365 0.16 ENST00000456980.1
ENST00000482274.2
ENST00000453710.1
ENST00000419242.1
ENST00000358603.2
ENST00000371226.3
ENST00000426139.1
OMA1
OMA1 zinc metallopeptidase
chr7_-_108209897 0.16 ENST00000313516.5
THAP5
THAP domain containing 5
chr7_-_34978980 0.16 ENST00000428054.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr12_+_80838126 0.16 ENST00000266688.5
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr19_+_9296279 0.15 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr4_+_95128748 0.15 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr12_-_15114658 0.15 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_84630645 0.15 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_+_106631966 0.15 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr11_-_6640585 0.15 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
TPP1
tripeptidyl peptidase I
chr6_-_114194483 0.15 ENST00000434296.2
RP1-249H1.4
RP1-249H1.4
chr12_-_22063787 0.15 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr2_+_171036635 0.15 ENST00000484338.2
ENST00000334231.6
MYO3B
myosin IIIB
chr3_+_44916098 0.15 ENST00000296125.4
TGM4
transglutaminase 4
chr2_+_161993465 0.15 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr19_+_15752088 0.15 ENST00000585846.1
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr11_+_7559485 0.15 ENST00000527790.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_-_57967854 0.15 ENST00000321039.3
VN1R1
vomeronasal 1 receptor 1
chr11_-_18062872 0.15 ENST00000250018.2
TPH1
tryptophan hydroxylase 1
chr13_-_76111945 0.15 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr12_-_15815626 0.15 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr9_-_99064429 0.15 ENST00000375263.3
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr1_+_87012922 0.15 ENST00000263723.5
CLCA4
chloride channel accessory 4
chr16_-_47493041 0.15 ENST00000565940.2
ITFG1
integrin alpha FG-GAP repeat containing 1
chr12_-_53601055 0.15 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
ITGB7
integrin, beta 7
chr7_+_37960163 0.14 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1
ependymin related 1
chr6_+_7590413 0.14 ENST00000342415.5
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr12_-_100656134 0.14 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr1_+_43424698 0.14 ENST00000431759.1
SLC2A1-AS1
SLC2A1 antisense RNA 1
chr19_-_44388116 0.14 ENST00000587539.1
ZNF404
zinc finger protein 404
chr2_-_74007193 0.14 ENST00000377706.4
ENST00000443070.1
ENST00000272444.3
DUSP11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr8_+_82066514 0.14 ENST00000519412.1
ENST00000521953.1
RP11-1149M10.2
RP11-1149M10.2
chr4_+_165675197 0.14 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr12_+_119772502 0.14 ENST00000536742.1
ENST00000327554.2
CCDC60
coiled-coil domain containing 60
chr15_+_23255242 0.14 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr2_-_134326009 0.14 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr9_-_40792063 0.14 ENST00000377626.3
ENST00000441795.1
ENST00000602553.1
ZNF658
zinc finger protein 658
chr4_+_126315091 0.14 ENST00000335110.5
FAT4
FAT atypical cadherin 4
chr3_-_158390282 0.14 ENST00000264265.3
LXN
latexin
chr3_-_170588163 0.14 ENST00000295830.8
RPL22L1
ribosomal protein L22-like 1
chr14_+_56127989 0.14 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr18_+_29027696 0.14 ENST00000257189.4
DSG3
desmoglein 3
chr4_+_141264597 0.14 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr12_+_119772734 0.14 ENST00000539847.1
CCDC60
coiled-coil domain containing 60
chr18_+_61445007 0.14 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr8_+_97597148 0.14 ENST00000521590.1
SDC2
syndecan 2
chr8_+_109455830 0.14 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr1_+_196621156 0.14 ENST00000359637.2
CFH
complement factor H
chr8_-_42358742 0.14 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chrX_-_30877837 0.14 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr7_-_92146729 0.14 ENST00000541751.1
PEX1
peroxisomal biogenesis factor 1
chr4_+_78804393 0.14 ENST00000502384.1
MRPL1
mitochondrial ribosomal protein L1
chr2_-_88285309 0.14 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr5_+_67588391 0.13 ENST00000523872.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr8_+_42911552 0.13 ENST00000525699.1
ENST00000529687.1
FNTA
farnesyltransferase, CAAX box, alpha
chr10_-_116418053 0.13 ENST00000277895.5
ABLIM1
actin binding LIM protein 1
chr3_-_149095652 0.13 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.4 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 0.3 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.7 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.3 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.1 0.6 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 0.4 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.6 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.1 GO:0050904 diapedesis(GO:0050904)
0.1 0.6 GO:0097338 response to clozapine(GO:0097338)
0.1 0.2 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.2 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.5 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.3 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0071047 nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.3 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.2 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:0060915 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:1903249 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.4 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 0.7 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.1 GO:0097325 melanocyte proliferation(GO:0097325) melanocyte apoptotic process(GO:1902362)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106)
0.0 0.1 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305)
0.0 0.3 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0033007 negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.0 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0048806 genitalia development(GO:0048806)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.0 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.0 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:1901558 pancreatic stellate cell proliferation(GO:0072343) response to metformin(GO:1901558) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.4 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.6 GO:0031403 lithium ion binding(GO:0031403)
0.1 0.4 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.6 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.2 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.2 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.1 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.0 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters