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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GATA2

Z-value: 0.74

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Transcription factors associated with GATA2

Gene Symbol Gene ID Gene Info
GATA2
ENSG00000179348.7 GATA binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA2hg19_v2_chr3_-_128207349_128207386-0.552.6e-01Click!

Activity profile of GATA2 motif

Sorted Z-values of GATA2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_70036164 0.42 ENST00000602013.1
AC007461.1
Uncharacterized protein
chr10_+_90484301 0.39 ENST00000404190.1
LIPK
lipase, family member K
chr4_-_140544386 0.34 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr2_+_114163945 0.33 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr1_+_193028717 0.31 ENST00000415442.2
ENST00000506303.1
TROVE2
TROVE domain family, member 2
chr2_-_37501692 0.28 ENST00000443977.1
PRKD3
protein kinase D3
chr3_-_69590486 0.28 ENST00000497880.1
FRMD4B
FERM domain containing 4B
chr6_-_32557610 0.26 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr10_+_6625605 0.25 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr1_-_113160826 0.24 ENST00000538187.1
ENST00000369664.1
ST7L
suppression of tumorigenicity 7 like
chr17_+_4853442 0.23 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr12_-_8815299 0.23 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr12_+_25205155 0.22 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr4_+_89300158 0.22 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr11_-_111649074 0.22 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr10_-_75351088 0.22 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr15_-_41120896 0.22 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr4_-_69434245 0.22 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr15_+_86098670 0.21 ENST00000558811.1
AKAP13
A kinase (PRKA) anchor protein 13
chr22_-_28392227 0.21 ENST00000431039.1
TTC28
tetratricopeptide repeat domain 28
chr3_-_178969403 0.21 ENST00000314235.5
ENST00000392685.2
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr1_+_198189921 0.19 ENST00000391974.3
NEK7
NIMA-related kinase 7
chr13_+_43148281 0.19 ENST00000239849.6
ENST00000398795.2
ENST00000544862.1
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr8_-_124665190 0.19 ENST00000325995.7
KLHL38
kelch-like family member 38
chr6_+_80129989 0.19 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr14_-_61190754 0.19 ENST00000216513.4
SIX4
SIX homeobox 4
chr9_-_130700080 0.19 ENST00000373110.4
DPM2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr13_+_32838801 0.19 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr11_+_124824000 0.18 ENST00000529051.1
ENST00000344762.5
CCDC15
coiled-coil domain containing 15
chr10_-_128110441 0.18 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr9_+_2029019 0.18 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_-_142077569 0.18 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1
fibroblast growth factor 1 (acidic)
chr4_+_154073469 0.18 ENST00000441616.1
TRIM2
tripartite motif containing 2
chr11_-_10920838 0.18 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr5_-_20575959 0.17 ENST00000507958.1
CDH18
cadherin 18, type 2
chr19_+_7011509 0.17 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr5_+_36608280 0.17 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_186732892 0.16 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2
sorbin and SH3 domain containing 2
chr14_+_21249200 0.16 ENST00000304677.2
RNASE6
ribonuclease, RNase A family, k6
chr4_-_76008706 0.16 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5
RP11-44F21.5
chr22_-_45608237 0.16 ENST00000492273.1
KIAA0930
KIAA0930
chr2_-_231989808 0.16 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr2_-_169769787 0.16 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chr12_+_65996599 0.16 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr3_+_111718173 0.15 ENST00000494932.1
TAGLN3
transgelin 3
chr8_-_27468717 0.15 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr6_+_148593425 0.15 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr12_+_116985896 0.15 ENST00000547114.1
RP11-809C9.2
RP11-809C9.2
chrX_-_20074895 0.15 ENST00000543767.1
MAP7D2
MAP7 domain containing 2
chr16_+_68071816 0.15 ENST00000562246.1
DUS2
dihydrouridine synthase 2
chr18_-_53303123 0.15 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr7_-_120498357 0.15 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr7_-_117512264 0.14 ENST00000454375.1
CTTNBP2
cortactin binding protein 2
chr12_-_12509929 0.14 ENST00000381800.2
LOH12CR2
loss of heterozygosity, 12, chromosomal region 2 (non-protein coding)
chr3_-_180397256 0.14 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr9_+_82267508 0.14 ENST00000490347.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_47131521 0.14 ENST00000542495.1
ENST00000532925.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr9_-_21077939 0.14 ENST00000380232.2
IFNB1
interferon, beta 1, fibroblast
chr17_+_78010428 0.14 ENST00000397545.4
ENST00000374877.3
ENST00000269318.5
ENST00000374876.4
ENST00000576033.1
ENST00000574099.1
CCDC40
coiled-coil domain containing 40
chr13_-_52026730 0.14 ENST00000420668.2
INTS6
integrator complex subunit 6
chr9_-_14180778 0.14 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr1_+_41204506 0.14 ENST00000525290.1
ENST00000530965.1
ENST00000416859.2
ENST00000308733.5
NFYC
nuclear transcription factor Y, gamma
chr10_-_90712520 0.14 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr19_-_54106751 0.14 ENST00000600193.1
CTB-167G5.5
Uncharacterized protein
chr5_+_36606992 0.14 ENST00000505202.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_115632035 0.13 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2
tetraspanin 2
chr11_-_126174186 0.13 ENST00000524964.1
RP11-712L6.5
Uncharacterized protein
chr8_-_67525524 0.13 ENST00000517885.1
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr2_+_219472637 0.13 ENST00000417849.1
PLCD4
phospholipase C, delta 4
chr2_+_219472488 0.13 ENST00000450993.2
PLCD4
phospholipase C, delta 4
chr6_+_63921399 0.13 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr11_-_133826852 0.13 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr10_+_7860460 0.13 ENST00000344293.5
TAF3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr7_+_116660246 0.13 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr5_+_36606700 0.13 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_+_124609823 0.13 ENST00000412681.2
NRGN
neurogranin (protein kinase C substrate, RC3)
chr14_+_21569245 0.12 ENST00000556585.2
TMEM253
transmembrane protein 253
chr6_-_75953484 0.12 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr9_-_3489406 0.12 ENST00000457373.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr12_-_7596735 0.12 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr11_-_59633951 0.12 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr12_-_8815215 0.12 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr11_-_119993734 0.12 ENST00000533302.1
TRIM29
tripartite motif containing 29
chr17_+_31318886 0.12 ENST00000269053.3
ENST00000394638.1
SPACA3
sperm acrosome associated 3
chr4_+_187112674 0.12 ENST00000378802.4
CYP4V2
cytochrome P450, family 4, subfamily V, polypeptide 2
chr6_-_31080336 0.12 ENST00000259870.3
C6orf15
chromosome 6 open reading frame 15
chr17_-_4689649 0.12 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr7_+_127233689 0.12 ENST00000265825.5
ENST00000420086.2
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr3_-_131756559 0.12 ENST00000505957.1
CPNE4
copine IV
chr8_+_70404996 0.12 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr6_+_155443048 0.11 ENST00000535583.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chr16_+_58074069 0.11 ENST00000570065.1
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr12_-_95010147 0.11 ENST00000548918.1
TMCC3
transmembrane and coiled-coil domain family 3
chr10_-_51958906 0.11 ENST00000489640.1
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr8_-_123139423 0.11 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chr3_-_100566492 0.11 ENST00000528490.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr12_-_11508520 0.11 ENST00000545626.1
ENST00000500254.2
PRB1
proline-rich protein BstNI subfamily 1
chr15_+_45879964 0.11 ENST00000565409.1
ENST00000564765.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr9_-_47314222 0.11 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
AL953854.2
chr1_+_81106951 0.11 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr6_-_43496605 0.11 ENST00000455285.2
XPO5
exportin 5
chr11_-_5248294 0.11 ENST00000335295.4
HBB
hemoglobin, beta
chr16_-_72698834 0.11 ENST00000570152.1
ENST00000561611.2
ENST00000570035.1
AC004158.2
AC004158.2
chr6_+_27215494 0.11 ENST00000230582.3
PRSS16
protease, serine, 16 (thymus)
chr1_-_152552980 0.11 ENST00000368787.3
LCE3D
late cornified envelope 3D
chr11_+_124609742 0.11 ENST00000284292.6
NRGN
neurogranin (protein kinase C substrate, RC3)
chr2_+_44502597 0.11 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr12_-_58145889 0.10 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chr10_-_93669233 0.10 ENST00000311575.5
FGFBP3
fibroblast growth factor binding protein 3
chrX_-_78622805 0.10 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr1_+_222791417 0.10 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
MIA3
melanoma inhibitory activity family, member 3
chr17_-_15165854 0.10 ENST00000395936.1
ENST00000395938.2
PMP22
peripheral myelin protein 22
chr3_+_194406603 0.10 ENST00000329759.4
FAM43A
family with sequence similarity 43, member A
chr1_-_182369751 0.10 ENST00000367565.1
TEDDM1
transmembrane epididymal protein 1
chr13_+_51913819 0.10 ENST00000419898.2
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chrX_+_80457442 0.10 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr4_+_20255123 0.10 ENST00000504154.1
ENST00000273739.5
SLIT2
slit homolog 2 (Drosophila)
chr5_-_41870621 0.10 ENST00000196371.5
OXCT1
3-oxoacid CoA transferase 1
chr7_+_74379083 0.10 ENST00000361825.7
GATSL1
GATS protein-like 1
chr15_-_66790146 0.10 ENST00000316634.5
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr1_-_241799232 0.10 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chrX_+_149531524 0.10 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr11_+_111385497 0.10 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
C11orf88
chromosome 11 open reading frame 88
chr4_+_26323764 0.10 ENST00000514730.1
ENST00000507574.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr11_+_122733011 0.10 ENST00000533709.1
CRTAM
cytotoxic and regulatory T cell molecule
chr3_-_24207039 0.10 ENST00000280696.5
THRB
thyroid hormone receptor, beta
chr16_-_30023615 0.10 ENST00000564979.1
ENST00000563378.1
DOC2A
double C2-like domains, alpha
chr18_-_47017956 0.10 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr5_-_180665195 0.10 ENST00000509148.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr5_+_172483347 0.10 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr13_+_53191605 0.10 ENST00000342657.3
ENST00000398039.1
HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr11_-_96076334 0.10 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr11_-_82708519 0.10 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr22_-_46450024 0.10 ENST00000396008.2
ENST00000333761.1
C22orf26
chromosome 22 open reading frame 26
chr12_-_96336369 0.10 ENST00000546947.1
ENST00000546386.1
CCDC38
coiled-coil domain containing 38
chr12_-_47219733 0.09 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4
solute carrier family 38, member 4
chr14_-_36645674 0.09 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr1_+_78511586 0.09 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr1_-_40562908 0.09 ENST00000527311.2
ENST00000449045.2
ENST00000372779.4
PPT1
palmitoyl-protein thioesterase 1
chr1_+_183774285 0.09 ENST00000539189.1
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr17_-_26733604 0.09 ENST00000584426.1
ENST00000584995.1
SLC46A1
solute carrier family 46 (folate transporter), member 1
chrX_+_100646190 0.09 ENST00000471855.1
RPL36A
ribosomal protein L36a
chr16_-_2260834 0.09 ENST00000562360.1
ENST00000566018.1
BRICD5
BRICHOS domain containing 5
chr17_+_44803922 0.09 ENST00000465370.1
NSF
N-ethylmaleimide-sensitive factor
chr14_+_100531738 0.09 ENST00000555706.1
EVL
Enah/Vasp-like
chr2_+_201936458 0.09 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr6_-_41130841 0.09 ENST00000373122.4
TREM2
triggering receptor expressed on myeloid cells 2
chr1_+_84630053 0.09 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_102803163 0.09 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr6_+_131958436 0.09 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr2_-_207082748 0.09 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr14_-_31926623 0.09 ENST00000356180.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr14_+_74353320 0.09 ENST00000540593.1
ENST00000555730.1
ZNF410
zinc finger protein 410
chr10_+_112404132 0.09 ENST00000369519.3
RBM20
RNA binding motif protein 20
chr6_+_45296391 0.09 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr12_+_21207503 0.09 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr15_-_49913126 0.09 ENST00000561064.1
ENST00000299338.6
FAM227B
family with sequence similarity 227, member B
chr13_+_53602894 0.09 ENST00000219022.2
OLFM4
olfactomedin 4
chr9_+_125437315 0.09 ENST00000304820.2
OR1L3
olfactory receptor, family 1, subfamily L, member 3
chrX_-_38080077 0.09 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
SRPX
sushi-repeat containing protein, X-linked
chr4_-_186733363 0.09 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr2_-_70520832 0.09 ENST00000454893.1
ENST00000272348.2
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr3_-_197676740 0.09 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
IQCG
IQ motif containing G
chr15_-_51397473 0.09 ENST00000327536.5
TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr12_-_11548496 0.09 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr3_+_72937182 0.09 ENST00000389617.4
GXYLT2
glucoside xylosyltransferase 2
chr12_+_94656297 0.09 ENST00000545312.1
PLXNC1
plexin C1
chrX_-_50386648 0.09 ENST00000460112.3
SHROOM4
shroom family member 4
chr13_+_103451399 0.09 ENST00000257336.1
ENST00000448849.2
BIVM
basic, immunoglobulin-like variable motif containing
chr1_-_152131703 0.09 ENST00000316073.3
RPTN
repetin
chr15_+_45003675 0.08 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr10_+_63808970 0.08 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_-_224624730 0.08 ENST00000445239.1
WDR26
WD repeat domain 26
chr5_-_132200477 0.08 ENST00000296875.2
GDF9
growth differentiation factor 9
chr12_-_42878101 0.08 ENST00000552108.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr14_+_62462541 0.08 ENST00000430451.2
SYT16
synaptotagmin XVI
chr2_-_99485825 0.08 ENST00000423771.1
KIAA1211L
KIAA1211-like
chr9_+_117904097 0.08 ENST00000374016.1
DEC1
deleted in esophageal cancer 1
chr2_-_190446738 0.08 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr9_+_21440440 0.08 ENST00000276927.1
IFNA1
interferon, alpha 1
chr6_-_56492816 0.08 ENST00000522360.1
DST
dystonin
chr15_+_90735145 0.08 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_+_17393888 0.08 ENST00000493172.1
ENST00000465994.1
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr15_-_63449663 0.08 ENST00000439025.1
RPS27L
ribosomal protein S27-like
chr4_+_113970772 0.08 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr9_-_139258159 0.08 ENST00000371739.3
DNLZ
DNL-type zinc finger
chr2_-_120980939 0.08 ENST00000426077.2
TMEM185B
transmembrane protein 185B
chr19_+_42254885 0.08 ENST00000595740.1
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr16_+_20911174 0.08 ENST00000568663.1
LYRM1
LYR motif containing 1
chr10_-_105677886 0.08 ENST00000224950.3
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr20_-_20033052 0.08 ENST00000536226.1
CRNKL1
crooked neck pre-mRNA splicing factor 1
chr6_-_154751629 0.08 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr19_-_54726850 0.08 ENST00000245620.9
ENST00000346401.6
ENST00000424807.1
ENST00000445347.1
LILRB3
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
chr18_-_2982869 0.08 ENST00000584915.1
LPIN2
lipin 2
chr5_-_180287663 0.08 ENST00000509066.1
ENST00000504225.1
ZFP62
ZFP62 zinc finger protein
chr18_-_47018769 0.08 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17
ribosomal protein L17
chr7_-_99527243 0.08 ENST00000312891.2
GJC3
gap junction protein, gamma 3, 30.2kDa
chr2_-_197041193 0.08 ENST00000409228.1
STK17B
serine/threonine kinase 17b
chr10_+_101542462 0.08 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr5_-_42812143 0.08 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:1904435 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.2 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0042127 regulation of cell proliferation(GO:0042127)
0.0 0.1 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.3 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.1 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.3 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0002588 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0060915 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.0 0.2 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0 0.1 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0001519 peptide amidation(GO:0001519) peptide modification(GO:0031179)
0.0 0.1 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.0 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.1 GO:1903284 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.0 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.1 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.0 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.1 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.2 GO:1904847 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.0 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:1990822 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.0 0.0 GO:0060254 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.0 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.0 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.0 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.0 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.0 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0042565 nuclear RNA export factor complex(GO:0042272) RNA nuclear export complex(GO:0042565)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.0 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.0 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.0 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.0 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.0 0.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse