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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GLIS3

Z-value: 0.27

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Transcription factors associated with GLIS3

Gene Symbol Gene ID Gene Info
ENSG00000107249.17 GLIS family zinc finger 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS3hg19_v2_chr9_-_4299874_4299916-0.001.0e+00Click!

Activity profile of GLIS3 motif

Sorted Z-values of GLIS3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_65958693 0.22 ENST00000445681.1
ENST00000452565.1
GS1-124K5.4
chr7_-_127032114 0.18 ENST00000436992.1
zinc finger protein 800
chr6_+_89791507 0.17 ENST00000354922.3
proline-rich nuclear receptor coactivator 1
chr19_+_40697514 0.16 ENST00000253055.3
mitogen-activated protein kinase kinase kinase 10
chr11_+_68451943 0.14 ENST00000265643.3
galanin/GMAP prepropeptide
chr12_+_132312931 0.13 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
matrix metallopeptidase 17 (membrane-inserted)
chr22_+_50628999 0.10 ENST00000395827.1
TraB domain containing
chr19_-_10613361 0.10 ENST00000591039.1
ENST00000591419.1
kelch-like ECH-associated protein 1
chr19_-_10613862 0.10 ENST00000592055.1
kelch-like ECH-associated protein 1
chr7_+_150758642 0.09 ENST00000488420.1
solute carrier family 4 (anion exchanger), member 2
chr19_-_48673552 0.09 ENST00000536218.1
ENST00000596549.1
ligase I, DNA, ATP-dependent
chr7_+_150758304 0.08 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
solute carrier family 4 (anion exchanger), member 2
chr9_+_131903916 0.07 ENST00000419582.1
protein phosphatase 2A activator, regulatory subunit 4
chr1_+_107599267 0.07 ENST00000361318.5
ENST00000370078.1
protein arginine methyltransferase 6
chr1_+_31886653 0.07 ENST00000536384.1
serine incorporator 2
chr12_+_48152774 0.07 ENST00000549243.1
solute carrier family 48 (heme transporter), member 1
chr1_+_59250815 0.07 ENST00000544621.1
ENST00000419531.2
long intergenic non-protein coding RNA 1135
chr9_+_131904233 0.06 ENST00000432651.1
ENST00000435132.1
protein phosphatase 2A activator, regulatory subunit 4
chr19_+_41281060 0.06 ENST00000594436.1
ENST00000597784.1
melanoma inhibitory activity
chr11_+_393428 0.06 ENST00000533249.1
ENST00000527442.1
plakophilin 3
chr1_-_22215192 0.06 ENST00000374673.3
heparan sulfate proteoglycan 2
chr9_+_131904295 0.06 ENST00000434095.1
protein phosphatase 2A activator, regulatory subunit 4
chr19_-_48673465 0.06 ENST00000598938.1
ligase I, DNA, ATP-dependent
chr5_+_41925325 0.05 ENST00000296812.2
ENST00000281623.3
ENST00000509134.1
F-box protein 4
chr11_-_118789613 0.05 ENST00000532899.1
B-cell CLL/lymphoma 9-like
chrX_-_132549506 0.05 ENST00000370828.3
glypican 4
chr22_-_31742218 0.04 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
POZ (BTB) and AT hook containing zinc finger 1
chr6_+_44191290 0.04 ENST00000371755.3
ENST00000371740.5
ENST00000371731.1
ENST00000393841.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr17_-_5015129 0.03 ENST00000575898.1
ENST00000416429.2
zinc finger protein 232
chr5_+_172386517 0.03 ENST00000519522.1
ribosomal protein L26-like 1
chr5_-_180671172 0.03 ENST00000512805.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr22_-_50964849 0.03 ENST00000543927.1
ENST00000423348.1
SCO2 cytochrome c oxidase assembly protein
chr19_-_41859814 0.03 ENST00000221930.5
transforming growth factor, beta 1
chr19_+_13875316 0.03 ENST00000319545.8
ENST00000593245.1
ENST00000040663.6
methylthioribose-1-phosphate isomerase 1
chr8_+_125860939 0.03 ENST00000525292.1
ENST00000528090.1
long intergenic non-protein coding RNA 964
chr15_+_91478493 0.02 ENST00000418476.2
unc-45 homolog A (C. elegans)
chr12_+_132568814 0.02 ENST00000454179.2
ENST00000389560.2
ENST00000443539.2
ENST00000392352.1
EP400 N-terminal like
chr19_-_49828438 0.02 ENST00000454748.3
ENST00000598828.1
ENST00000335875.4
solute carrier family 6, member 16
chr16_+_30006615 0.02 ENST00000563197.1
INO80 complex subunit E
chr12_-_48152611 0.02 ENST00000389212.3
Rap guanine nucleotide exchange factor (GEF) 3
chr3_-_160167301 0.02 ENST00000494486.1
tripartite motif containing 59
chr11_+_68671310 0.02 ENST00000255078.3
ENST00000539224.1
immunoglobulin mu binding protein 2
chr6_+_44191507 0.02 ENST00000371724.1
ENST00000371713.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr22_-_21482352 0.02 ENST00000329949.3
POM121 transmembrane nucleoporin-like 7
chr19_+_46850251 0.02 ENST00000012443.4
protein phosphatase 5, catalytic subunit
chr9_-_139658965 0.02 ENST00000316144.5
lipocalin 15
chr20_-_30310693 0.02 ENST00000307677.4
ENST00000420653.1
BCL2-like 1
chr20_-_30310656 0.02 ENST00000376055.4
BCL2-like 1
chr19_+_48828582 0.02 ENST00000270221.6
ENST00000596315.1
epithelial membrane protein 3
chr9_-_130742792 0.01 ENST00000373095.1
family with sequence similarity 102, member A
chr20_+_18447771 0.01 ENST00000377603.4
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr20_-_6103666 0.01 ENST00000536936.1
fermitin family member 1
chr3_+_38029462 0.01 ENST00000283713.6
villin-like
chr20_-_44718538 0.01 ENST00000290231.6
ENST00000372291.3
nuclear receptor coactivator 5
chr12_-_57400227 0.01 ENST00000300101.2
zinc finger and BTB domain containing 39
chr15_-_43882353 0.01 ENST00000453080.1
ENST00000360301.4
ENST00000360135.4
ENST00000417085.1
ENST00000431962.1
ENST00000334933.4
ENST00000381879.4
ENST00000420765.1
diphosphoinositol pentakisphosphate kinase 1
chr14_+_77228532 0.01 ENST00000167106.4
ENST00000554237.1
vasohibin 1
chr15_-_43882140 0.01 ENST00000429176.1
diphosphoinositol pentakisphosphate kinase 1
chr6_+_33172407 0.01 ENST00000374662.3
hydroxysteroid (17-beta) dehydrogenase 8
chr5_-_137090028 0.01 ENST00000314940.4
heterogeneous nuclear ribonucleoprotein A0
chrX_+_118370211 0.01 ENST00000217971.7
progesterone receptor membrane component 1
chr3_+_127348005 0.01 ENST00000342480.6
podocalyxin-like 2
chr19_+_46850320 0.01 ENST00000391919.1
protein phosphatase 5, catalytic subunit
chr8_-_12051576 0.01 ENST00000524571.2
ENST00000533852.2
ENST00000533513.1
ENST00000448228.2
ENST00000534520.1
ENST00000321602.8
family with sequence similarity 86, member B1
chr8_+_118147498 0.01 ENST00000519688.1
ENST00000456015.2
solute carrier family 30 (zinc transporter), member 8
chr3_-_160167508 0.01 ENST00000479460.1
tripartite motif containing 59
chr1_-_157108266 0.01 ENST00000326786.4
ets variant 3
chr20_+_61867235 0.00 ENST00000342412.6
ENST00000217169.3
baculoviral IAP repeat containing 7
chr2_+_220379052 0.00 ENST00000347842.3
ENST00000358078.4
acid-sensing (proton-gated) ion channel family member 4
chr7_+_23636992 0.00 ENST00000307471.3
ENST00000409765.1
coiled-coil domain containing 126
chr9_-_98279241 0.00 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
patched 1
chr7_-_50518022 0.00 ENST00000356889.4
ENST00000420829.1
ENST00000448788.1
ENST00000395556.2
ENST00000422854.1
ENST00000435566.1
ENST00000433017.1
fidgetin-like 1
chr17_-_73179046 0.00 ENST00000314523.7
ENST00000420826.2
small ubiquitin-like modifier 2

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0042756 drinking behavior(GO:0042756)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)