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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GMEB2

Z-value: 2.25

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Transcription factors associated with GMEB2

Gene Symbol Gene ID Gene Info
GMEB2
ENSG00000101216.6 glucocorticoid modulatory element binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GMEB2hg19_v2_chr20_-_62258394_62258464-0.404.3e-01Click!

Activity profile of GMEB2 motif

Sorted Z-values of GMEB2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_57261859 2.08 ENST00000495803.1
ENST00000444459.1
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr8_+_103876528 1.98 ENST00000522939.1
ENST00000524007.1
KB-1507C5.2
HCG15011, isoform CRA_a; Protein LOC100996457
chr2_+_28974489 1.53 ENST00000455580.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr1_+_42921761 1.36 ENST00000372562.1
PPCS
phosphopantothenoylcysteine synthetase
chr11_-_2906979 1.35 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr7_+_120590803 1.35 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chr19_-_40562063 1.34 ENST00000598845.1
ENST00000593605.1
ENST00000221355.6
ENST00000434248.1
ZNF780B
zinc finger protein 780B
chr17_+_4046964 1.30 ENST00000573984.1
CYB5D2
cytochrome b5 domain containing 2
chr18_+_2571510 1.30 ENST00000261597.4
ENST00000575515.1
NDC80
NDC80 kinetochore complex component
chr5_+_162887556 1.26 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR
hyaluronan-mediated motility receptor (RHAMM)
chr2_+_99758161 1.25 ENST00000409684.1
C2ORF15
Uncharacterized protein C2orf15
chr7_+_72742178 1.20 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr4_+_26859300 1.20 ENST00000494628.2
STIM2
stromal interaction molecule 2
chr18_-_2571210 1.12 ENST00000577166.1
METTL4
methyltransferase like 4
chr19_+_10527449 1.04 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr17_-_15903002 1.03 ENST00000399277.1
ZSWIM7
zinc finger, SWIM-type containing 7
chr3_+_180319918 0.99 ENST00000296015.4
ENST00000491380.1
ENST00000412756.2
ENST00000382584.4
TTC14
tetratricopeptide repeat domain 14
chr15_+_45879595 0.96 ENST00000565216.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr12_+_21654714 0.95 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr14_-_53258180 0.95 ENST00000554230.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr15_-_65282045 0.94 ENST00000558765.1
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr4_-_76439483 0.94 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chrX_+_148622138 0.90 ENST00000450602.2
ENST00000441248.1
CXorf40A
chromosome X open reading frame 40A
chr13_-_33112899 0.90 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
N4BP2L2
NEDD4 binding protein 2-like 2
chr15_-_65281775 0.88 ENST00000433215.2
ENST00000558415.1
ENST00000557795.1
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr15_-_35280426 0.88 ENST00000559564.1
ENST00000356321.4
ZNF770
zinc finger protein 770
chr14_-_53258314 0.88 ENST00000216410.3
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr15_-_52861029 0.86 ENST00000561650.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr8_+_109455830 0.86 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr21_+_38445539 0.85 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr1_+_28099700 0.83 ENST00000440806.2
STX12
syntaxin 12
chr16_-_3493528 0.82 ENST00000301744.4
ZNF597
zinc finger protein 597
chr13_-_33112823 0.82 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr21_-_30365136 0.81 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr17_-_15902903 0.81 ENST00000486655.1
ZSWIM7
zinc finger, SWIM-type containing 7
chr2_+_223726281 0.79 ENST00000413316.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr7_-_108209897 0.79 ENST00000313516.5
THAP5
THAP domain containing 5
chrX_-_119693745 0.77 ENST00000371323.2
CUL4B
cullin 4B
chrX_-_54069253 0.77 ENST00000425862.1
ENST00000433120.1
PHF8
PHD finger protein 8
chr1_+_74663896 0.77 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
FPGT
FPGT-TNNI3K
TNNI3K
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr14_+_75536335 0.76 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr19_-_52097613 0.76 ENST00000301439.3
AC018755.1
HCG2008157; Uncharacterized protein; cDNA FLJ30403 fis, clone BRACE2008480
chr1_-_229644034 0.75 ENST00000366678.3
ENST00000261396.3
ENST00000537506.1
NUP133
nucleoporin 133kDa
chr2_+_189156586 0.74 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr13_-_33112956 0.74 ENST00000505213.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr2_+_109403193 0.73 ENST00000412964.2
ENST00000295124.4
CCDC138
coiled-coil domain containing 138
chr2_+_46769798 0.73 ENST00000238738.4
RHOQ
ras homolog family member Q
chr10_+_22610876 0.73 ENST00000442508.1
BMI1
BMI1 polycomb ring finger oncogene
chr12_-_44200146 0.72 ENST00000395510.2
ENST00000325127.4
TWF1
twinfilin actin-binding protein 1
chr2_-_128145498 0.72 ENST00000409179.2
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr6_-_109703634 0.71 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164
CD164 molecule, sialomucin
chr10_+_35416223 0.69 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr2_+_189156721 0.69 ENST00000409927.1
ENST00000409805.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr4_+_170541678 0.69 ENST00000360642.3
ENST00000512813.1
CLCN3
chloride channel, voltage-sensitive 3
chr4_-_76439596 0.68 ENST00000451788.1
ENST00000512706.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr1_+_6845578 0.68 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr4_-_39460496 0.68 ENST00000449470.2
RPL9
ribosomal protein L9
chr17_-_58469591 0.68 ENST00000589335.1
USP32
ubiquitin specific peptidase 32
chr7_-_35840198 0.66 ENST00000412856.1
ENST00000437235.3
ENST00000424194.1
AC007551.3
AC007551.3
chr5_-_89825328 0.66 ENST00000500869.2
ENST00000315948.6
ENST00000509384.1
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr13_-_76111945 0.66 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr14_-_54908043 0.64 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr1_-_67142710 0.64 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr3_-_170587974 0.64 ENST00000463836.1
RPL22L1
ribosomal protein L22-like 1
chr1_+_42922173 0.64 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS
phosphopantothenoylcysteine synthetase
chrX_+_95939638 0.63 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr13_-_108867846 0.63 ENST00000442234.1
LIG4
ligase IV, DNA, ATP-dependent
chr16_-_89768035 0.63 ENST00000569918.1
SPATA2L
spermatogenesis associated 2-like
chr12_+_133707570 0.63 ENST00000416488.1
ENST00000540096.2
ZNF268
CTD-2140B24.4
zinc finger protein 268
Zinc finger protein 268
chr5_+_68665608 0.63 ENST00000509734.1
ENST00000354868.5
ENST00000521422.1
ENST00000354312.3
ENST00000345306.6
RAD17
RAD17 homolog (S. pombe)
chr1_-_100598444 0.62 ENST00000535161.1
ENST00000287482.5
SASS6
spindle assembly 6 homolog (C. elegans)
chr4_-_73935409 0.61 ENST00000507544.2
ENST00000295890.4
COX18
COX18 cytochrome C oxidase assembly factor
chr10_-_70092671 0.61 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD
phenazine biosynthesis-like protein domain containing
chr1_+_100435535 0.61 ENST00000427993.2
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr6_-_121655850 0.61 ENST00000422369.1
TBC1D32
TBC1 domain family, member 32
chr4_+_39460659 0.60 ENST00000513731.1
LIAS
lipoic acid synthetase
chr6_-_52860171 0.60 ENST00000370963.4
GSTA4
glutathione S-transferase alpha 4
chr2_+_71357744 0.60 ENST00000498451.2
MPHOSPH10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr6_+_75994709 0.60 ENST00000438676.1
ENST00000607221.1
RP1-234P15.4
RP1-234P15.4
chr3_-_101395936 0.60 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr10_-_70092635 0.60 ENST00000309049.4
PBLD
phenazine biosynthesis-like protein domain containing
chr14_-_39901618 0.59 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr3_-_20227619 0.59 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
SGOL1
shugoshin-like 1 (S. pombe)
chr10_+_91461337 0.58 ENST00000260753.4
ENST00000416354.1
ENST00000394289.2
ENST00000371728.3
KIF20B
kinesin family member 20B
chr11_+_31531291 0.58 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr15_-_23034322 0.57 ENST00000539711.2
ENST00000560039.1
ENST00000398013.3
ENST00000337451.3
ENST00000359727.4
ENST00000398014.2
NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
chr14_+_53196872 0.57 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr5_+_128301189 0.57 ENST00000395266.1
ENST00000506176.1
SLC27A6
solute carrier family 27 (fatty acid transporter), member 6
chr2_+_183989157 0.56 ENST00000541912.1
NUP35
nucleoporin 35kDa
chr2_-_222436988 0.56 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4
EPH receptor A4
chr8_+_117778736 0.56 ENST00000309822.2
ENST00000357148.3
ENST00000517814.1
ENST00000517820.1
UTP23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr2_+_99771418 0.55 ENST00000393473.2
ENST00000393477.3
ENST00000393474.3
ENST00000340066.1
ENST00000393471.2
ENST00000449211.1
ENST00000434566.1
ENST00000410042.1
LIPT1
MRPL30
lipoyltransferase 1
39S ribosomal protein L30, mitochondrial
chr10_+_60145155 0.55 ENST00000373895.3
TFAM
transcription factor A, mitochondrial
chr6_-_136571400 0.55 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
MTFR2
mitochondrial fission regulator 2
chr6_-_109703600 0.55 ENST00000512821.1
CD164
CD164 molecule, sialomucin
chr3_-_149688502 0.55 ENST00000481767.1
ENST00000475518.1
PFN2
profilin 2
chr18_+_13726645 0.55 ENST00000543302.2
ENST00000383314.2
ENST00000535051.1
ENST00000592764.1
ENST00000591746.1
RNMT
RNA (guanine-7-) methyltransferase
chr5_+_94890840 0.54 ENST00000504763.1
ARSK
arylsulfatase family, member K
chr3_-_170587815 0.54 ENST00000466674.1
RPL22L1
ribosomal protein L22-like 1
chr6_-_121655552 0.54 ENST00000275159.6
TBC1D32
TBC1 domain family, member 32
chr3_-_45883558 0.54 ENST00000445698.1
ENST00000296135.6
LZTFL1
leucine zipper transcription factor-like 1
chr15_+_45879964 0.54 ENST00000565409.1
ENST00000564765.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr2_-_188419078 0.54 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr1_+_92495528 0.54 ENST00000370383.4
EPHX4
epoxide hydrolase 4
chr18_-_2571437 0.54 ENST00000574676.1
ENST00000574538.1
ENST00000319888.6
METTL4
methyltransferase like 4
chr4_-_87813566 0.53 ENST00000504008.1
ENST00000506308.1
C4orf36
chromosome 4 open reading frame 36
chr6_+_126661253 0.53 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW
centromere protein W
chr12_+_102513950 0.53 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chr10_-_27444143 0.52 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr16_+_50059182 0.52 ENST00000562576.1
CNEP1R1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr1_+_206809113 0.52 ENST00000441486.1
ENST00000367106.1
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr4_+_25378912 0.52 ENST00000510092.1
ENST00000505991.1
ANAPC4
anaphase promoting complex subunit 4
chrX_+_133594168 0.52 ENST00000298556.7
HPRT1
hypoxanthine phosphoribosyltransferase 1
chr2_+_109335929 0.51 ENST00000283195.6
RANBP2
RAN binding protein 2
chr3_-_170588163 0.51 ENST00000295830.8
RPL22L1
ribosomal protein L22-like 1
chr2_+_189156389 0.51 ENST00000409843.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr5_+_94890778 0.51 ENST00000380009.4
ARSK
arylsulfatase family, member K
chr8_-_82598067 0.51 ENST00000523942.1
ENST00000522997.1
IMPA1
inositol(myo)-1(or 4)-monophosphatase 1
chr2_+_28974603 0.51 ENST00000441461.1
ENST00000358506.2
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr15_-_52861157 0.51 ENST00000564163.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr10_-_33625154 0.51 ENST00000265371.4
NRP1
neuropilin 1
chr3_-_134204815 0.50 ENST00000514612.1
ENST00000510994.1
ENST00000354910.5
ANAPC13
anaphase promoting complex subunit 13
chr17_-_58469329 0.50 ENST00000393003.3
USP32
ubiquitin specific peptidase 32
chr4_+_113152978 0.50 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr9_-_77643307 0.50 ENST00000376834.3
ENST00000376830.3
C9orf41
chromosome 9 open reading frame 41
chr4_+_113066552 0.50 ENST00000309733.5
C4orf32
chromosome 4 open reading frame 32
chr10_+_99079008 0.49 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr8_-_80680078 0.48 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr18_+_61143994 0.48 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr15_-_66084428 0.48 ENST00000443035.3
ENST00000431932.2
DENND4A
DENN/MADD domain containing 4A
chr1_+_236557569 0.47 ENST00000334232.4
EDARADD
EDAR-associated death domain
chr19_+_56989485 0.47 ENST00000585445.1
ENST00000586091.1
ENST00000594783.1
ENST00000592146.1
ENST00000588158.1
ENST00000299997.4
ENST00000591797.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr22_+_29469100 0.47 ENST00000327813.5
ENST00000407188.1
KREMEN1
kringle containing transmembrane protein 1
chr5_+_138940742 0.47 ENST00000398733.3
ENST00000253815.2
ENST00000505007.1
UBE2D2
ubiquitin-conjugating enzyme E2D 2
chr7_+_12726474 0.47 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ARL4A
ADP-ribosylation factor-like 4A
chr6_-_135375986 0.47 ENST00000525067.1
ENST00000367822.5
ENST00000367837.5
HBS1L
HBS1-like (S. cerevisiae)
chr8_+_38243721 0.47 ENST00000527334.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr1_-_193075180 0.46 ENST00000367440.3
GLRX2
glutaredoxin 2
chr1_-_185126037 0.46 ENST00000367506.5
ENST00000367504.3
TRMT1L
tRNA methyltransferase 1 homolog (S. cerevisiae)-like
chr13_-_33002151 0.46 ENST00000495479.1
ENST00000343281.4
ENST00000464470.1
ENST00000380139.4
ENST00000380133.2
N4BP2L1
NEDD4 binding protein 2-like 1
chr15_+_78832747 0.46 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr7_+_12726623 0.46 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chr1_-_112281875 0.45 ENST00000527621.1
ENST00000534365.1
ENST00000357260.5
FAM212B
family with sequence similarity 212, member B
chr5_-_82373260 0.45 ENST00000502346.1
TMEM167A
transmembrane protein 167A
chr2_+_183989083 0.45 ENST00000295119.4
NUP35
nucleoporin 35kDa
chr12_-_21654479 0.45 ENST00000421138.2
ENST00000444129.2
ENST00000539672.1
ENST00000542432.1
ENST00000536964.1
ENST00000536240.1
ENST00000396093.3
ENST00000314748.6
RECQL
RecQ protein-like (DNA helicase Q1-like)
chr11_-_95523500 0.45 ENST00000540054.1
FAM76B
family with sequence similarity 76, member B
chr11_+_61583968 0.45 ENST00000517839.1
FADS2
fatty acid desaturase 2
chr6_-_82957433 0.45 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr19_-_38210622 0.45 ENST00000591664.1
ENST00000355202.4
ZNF607
zinc finger protein 607
chr9_+_139846708 0.45 ENST00000371633.3
LCN12
lipocalin 12
chr2_-_44588893 0.45 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
PREPL
prolyl endopeptidase-like
chr9_+_88556444 0.45 ENST00000376040.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr2_+_153574428 0.44 ENST00000326446.5
ARL6IP6
ADP-ribosylation-like factor 6 interacting protein 6
chr1_-_220220000 0.44 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr7_+_120591170 0.44 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr18_+_61144160 0.44 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr6_-_75994536 0.44 ENST00000475111.2
ENST00000230461.6
TMEM30A
transmembrane protein 30A
chrX_-_109561294 0.44 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr4_-_129209221 0.44 ENST00000512483.1
PGRMC2
progesterone receptor membrane component 2
chr8_-_42396185 0.44 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr6_+_88032299 0.44 ENST00000608353.1
ENST00000392863.1
ENST00000229570.5
ENST00000608525.1
ENST00000608868.1
SMIM8
small integral membrane protein 8
chrX_+_133507327 0.44 ENST00000332070.3
ENST00000394292.1
ENST00000370799.1
ENST00000416404.2
PHF6
PHD finger protein 6
chr10_+_70883908 0.44 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr2_+_131369054 0.44 ENST00000409602.1
POTEJ
POTE ankyrin domain family, member J
chr4_+_159131630 0.43 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr11_-_8615687 0.43 ENST00000534493.1
ENST00000422559.2
STK33
serine/threonine kinase 33
chr11_-_73472096 0.43 ENST00000541588.1
ENST00000336083.3
ENST00000540771.1
ENST00000310653.6
RAB6A
RAB6A, member RAS oncogene family
chr2_+_189156638 0.43 ENST00000410051.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr4_+_76439665 0.42 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6
THAP domain containing 6
chr5_-_137368726 0.42 ENST00000420893.2
ENST00000425075.2
FAM13B
family with sequence similarity 13, member B
chr15_+_45879779 0.42 ENST00000566801.1
ENST00000568816.1
ENST00000565323.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr10_+_60144782 0.42 ENST00000487519.1
TFAM
transcription factor A, mitochondrial
chr6_-_121655593 0.42 ENST00000398212.2
TBC1D32
TBC1 domain family, member 32
chrX_+_95939711 0.41 ENST00000373049.4
ENST00000324765.8
DIAPH2
diaphanous-related formin 2
chr1_-_91487013 0.41 ENST00000347275.5
ENST00000370440.1
ZNF644
zinc finger protein 644
chr7_+_102715315 0.41 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10
armadillo repeat containing 10
chr12_+_102514019 0.41 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARPBP
PARP1 binding protein
chr5_-_74162605 0.41 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A
family with sequence similarity 169, member A
chr7_-_102985035 0.41 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr10_-_96122682 0.41 ENST00000371361.3
NOC3L
nucleolar complex associated 3 homolog (S. cerevisiae)
chr1_+_186344945 0.40 ENST00000419367.3
ENST00000287859.6
C1orf27
chromosome 1 open reading frame 27
chr4_+_170541660 0.40 ENST00000513761.1
ENST00000347613.4
CLCN3
chloride channel, voltage-sensitive 3
chr22_+_42017123 0.40 ENST00000360079.3
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr10_+_18948311 0.40 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr2_-_61244550 0.40 ENST00000421319.1
PUS10
pseudouridylate synthase 10
chr2_-_86790472 0.40 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr15_+_52311398 0.40 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr1_-_36916066 0.40 ENST00000315643.9
OSCP1
organic solute carrier partner 1
chr4_+_39460620 0.40 ENST00000340169.2
ENST00000261434.3
LIAS
lipoic acid synthetase
chr20_-_49575058 0.40 ENST00000371584.4
ENST00000371583.5
ENST00000413082.1
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr8_+_109455845 0.39 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr12_-_120884175 0.39 ENST00000546954.1
TRIAP1
TP53 regulated inhibitor of apoptosis 1
chr16_-_46655538 0.39 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr14_-_77495007 0.39 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr17_-_15902951 0.39 ENST00000472495.1
ZSWIM7
zinc finger, SWIM-type containing 7
chr2_-_222437049 0.39 ENST00000541600.1
EPHA4
EPH receptor A4
chr8_-_125384927 0.39 ENST00000297632.6
TMEM65
transmembrane protein 65
chr11_+_102980126 0.39 ENST00000375735.2
DYNC2H1
dynein, cytoplasmic 2, heavy chain 1
chr5_-_34008179 0.39 ENST00000426255.2
ENST00000502637.1
ENST00000335606.6
ENST00000441713.2
AMACR
alpha-methylacyl-CoA racemase

Network of associatons between targets according to the STRING database.

First level regulatory network of GMEB2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.3 1.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.3 0.8 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.3 1.0 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.3 1.8 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 1.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 1.2 GO:0035617 stress granule disassembly(GO:0035617)
0.2 0.7 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.2 1.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 1.6 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.2 1.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.6 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.2 0.6 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.2 0.6 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 0.8 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 1.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.2 0.8 GO:0051664 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.2 0.5 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 0.9 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.2 0.7 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.2 0.5 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.2 1.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 1.5 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 1.9 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
0.1 2.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.6 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.5 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.6 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.7 GO:0030047 actin modification(GO:0030047)
0.1 0.2 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.6 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 1.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) sensory neuron axon guidance(GO:0097374) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.3 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.3 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.1 0.3 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.1 0.6 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.7 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.1 GO:0018307 enzyme active site formation(GO:0018307)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 1.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 1.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.3 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 2.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.5 GO:0042126 nitrate metabolic process(GO:0042126)
0.1 0.7 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 1.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.8 GO:0042262 DNA protection(GO:0042262)
0.1 0.6 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.5 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.3 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.3 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.2 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.3 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.2 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1 0.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.3 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 1.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.1 GO:2000452 CD8-positive, alpha-beta T cell extravasation(GO:0035697) CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of T cell extravasation(GO:2000407) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0 0.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.2 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.3 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.0 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.2 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.3 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.5 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.9 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.4 GO:2001138 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.7 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0090656 t-circle formation(GO:0090656)
0.0 1.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.8 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.0 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.5 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0007498 mesoderm development(GO:0007498)
0.0 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.3 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.4 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.3 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.8 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.0 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 3.3 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.2 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.4 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.1 GO:2000255 regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.7 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.3 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0070206 protein trimerization(GO:0070206)
0.0 2.4 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.2 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.7 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.7 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.6 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 1.0 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.5 GO:0071901 negative regulation of protein serine/threonine kinase activity(GO:0071901)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.0 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 1.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.7 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.2 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 2.2 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.3 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.0 0.7 GO:0007099 centriole replication(GO:0007099)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.6 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.5 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 1.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.5 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:1901224 activation of NF-kappaB-inducing kinase activity(GO:0007250) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:1901189 arterial endothelial cell fate commitment(GO:0060844) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 2.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.6 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0051608 histamine transport(GO:0051608)
0.0 0.7 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.0 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.2 GO:0051014 actin filament fragmentation(GO:0030043) actin filament severing(GO:0051014)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.6 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.6 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.1 GO:0009887 organ morphogenesis(GO:0009887)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.3 GO:0050776 regulation of immune response(GO:0050776)
0.0 0.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0097196 Shu complex(GO:0097196)
0.2 1.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 2.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 2.7 GO:0042587 glycogen granule(GO:0042587)
0.2 0.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.5 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.9 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 1.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.6 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.4 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.6 GO:0098536 deuterosome(GO:0098536)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.2 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.3 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.1 0.2 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.7 GO:0000796 condensin complex(GO:0000796)
0.1 0.3 GO:0044423 virion(GO:0019012) virion part(GO:0044423)
0.0 0.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.5 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.4 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 1.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 1.2 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.6 GO:0070938 contractile ring(GO:0070938)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0000806 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 3.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.5 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 2.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.4 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0098559 cytoplasmic side of endosome membrane(GO:0010009) cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.7 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0005840 ribosome(GO:0005840)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.4 1.2 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.3 0.6 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.3 1.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 0.7 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.2 0.7 GO:0031685 adenosine receptor binding(GO:0031685)
0.2 1.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.0 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.2 0.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 0.7 GO:0032427 GBD domain binding(GO:0032427)
0.2 0.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 0.7 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.2 0.6 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 1.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.7 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.6 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.9 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.6 GO:0031403 lithium ion binding(GO:0031403)
0.1 1.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.3 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 2.5 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.4 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.3 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 1.0 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.3 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.2 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.1 0.2 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.8 GO:0031013 troponin I binding(GO:0031013)
0.1 0.5 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.3 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 0.2 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.2 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.2 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.1 0.3 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 1.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.2 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.1 0.5 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1 2.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 1.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.2 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.6 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.9 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.4 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 1.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.3 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 2.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.3 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 3.4 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.5 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.2 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 2.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 3.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 1.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 2.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 2.3 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.6 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
0.0 0.2 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)