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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GTF2I

Z-value: 1.02

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Transcription factors associated with GTF2I

Gene Symbol Gene ID Gene Info
GTF2I
ENSG00000077809.8 general transcription factor IIi

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GTF2Ihg19_v2_chr7_+_74072011_74072119-0.843.6e-02Click!

Activity profile of GTF2I motif

Sorted Z-values of GTF2I motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_50094866 0.67 ENST00000418929.2
PRR12
proline rich 12
chr2_+_45168875 0.65 ENST00000260653.3
SIX3
SIX homeobox 3
chr19_-_50990785 0.57 ENST00000595005.1
CTD-2545M3.8
CTD-2545M3.8
chr19_-_2015699 0.52 ENST00000255608.4
BTBD2
BTB (POZ) domain containing 2
chr5_+_172484377 0.51 ENST00000523161.1
CREBRF
CREB3 regulatory factor
chr12_+_58120044 0.49 ENST00000542466.2
AGAP2-AS1
AGAP2 antisense RNA 1
chr2_-_39664206 0.48 ENST00000484274.1
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr17_-_7120525 0.47 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
DLG4
discs, large homolog 4 (Drosophila)
chr12_-_50222187 0.45 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr12_-_1703331 0.45 ENST00000339235.3
FBXL14
F-box and leucine-rich repeat protein 14
chr9_+_19408919 0.42 ENST00000380376.1
ACER2
alkaline ceramidase 2
chr1_-_27930102 0.42 ENST00000247087.5
ENST00000374011.2
AHDC1
AT hook, DNA binding motif, containing 1
chr1_+_154975258 0.38 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr5_+_92919043 0.38 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr12_+_113012831 0.36 ENST00000547686.1
ENST00000543106.2
ENST00000551593.1
ENST00000546426.1
ENST00000551748.1
RPH3A
rabphilin 3A homolog (mouse)
chr2_+_219264762 0.36 ENST00000452977.1
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr18_+_46065570 0.36 ENST00000591412.1
CTIF
CBP80/20-dependent translation initiation factor
chr9_+_8858102 0.35 ENST00000447950.1
ENST00000430766.1
RP11-75C9.1
RP11-75C9.1
chr20_+_36531499 0.35 ENST00000373458.3
ENST00000373461.4
ENST00000373459.4
VSTM2L
V-set and transmembrane domain containing 2 like
chr17_+_73472575 0.34 ENST00000375248.5
KIAA0195
KIAA0195
chr19_-_49622348 0.34 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr7_+_150758642 0.33 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr17_-_1928621 0.33 ENST00000331238.6
RTN4RL1
reticulon 4 receptor-like 1
chr15_-_59041954 0.33 ENST00000439637.1
ENST00000558004.1
ADAM10
ADAM metallopeptidase domain 10
chr12_+_57998595 0.33 ENST00000337737.3
ENST00000548198.1
ENST00000551632.1
DTX3
deltex homolog 3 (Drosophila)
chr14_+_64971438 0.32 ENST00000555321.1
ZBTB1
zinc finger and BTB domain containing 1
chrX_-_1511617 0.32 ENST00000381401.5
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr5_+_149865377 0.32 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr11_-_72385437 0.32 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr19_-_54984354 0.31 ENST00000301200.2
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr17_+_60704762 0.31 ENST00000303375.5
MRC2
mannose receptor, C type 2
chr8_+_55467072 0.30 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr12_-_124873357 0.30 ENST00000448614.1
NCOR2
nuclear receptor corepressor 2
chr17_+_38171681 0.29 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr5_-_159739483 0.29 ENST00000519673.1
ENST00000541762.1
CCNJL
cyclin J-like
chr19_-_49015050 0.29 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr1_+_26737292 0.28 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr19_-_4065730 0.28 ENST00000601588.1
ZBTB7A
zinc finger and BTB domain containing 7A
chr11_+_394145 0.28 ENST00000528036.1
PKP3
plakophilin 3
chr19_-_36499521 0.28 ENST00000397428.3
ENST00000503121.1
ENST00000340477.5
ENST00000324444.3
ENST00000490730.1
SYNE4
spectrin repeat containing, nuclear envelope family member 4
chrY_-_1461617 0.27 ENSTR0000381401.5
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr10_+_88718397 0.27 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr14_+_24837226 0.27 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr6_-_31865452 0.27 ENST00000375530.4
ENST00000375537.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr1_-_47655686 0.26 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr11_+_394196 0.26 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr20_+_44637526 0.26 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr5_+_3596168 0.26 ENST00000302006.3
IRX1
iroquois homeobox 1
chr1_+_53793885 0.26 ENST00000445039.2
RP4-784A16.5
RP4-784A16.5
chr6_+_33378517 0.26 ENST00000428274.1
PHF1
PHD finger protein 1
chr20_+_43374421 0.26 ENST00000372861.3
KCNK15
potassium channel, subfamily K, member 15
chr19_+_12944722 0.26 ENST00000591495.1
MAST1
microtubule associated serine/threonine kinase 1
chr8_-_145018080 0.25 ENST00000354589.3
PLEC
plectin
chr6_+_41514305 0.25 ENST00000409208.1
ENST00000373057.3
FOXP4
forkhead box P4
chr15_+_90544532 0.25 ENST00000268154.4
ZNF710
zinc finger protein 710
chr17_-_40828969 0.25 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr16_-_88717482 0.25 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr1_+_154975110 0.25 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr16_+_2079501 0.24 ENST00000563587.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr6_-_10412600 0.24 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr9_-_8857776 0.24 ENST00000481079.1
PTPRD
protein tyrosine phosphatase, receptor type, D
chr8_-_11058847 0.24 ENST00000297303.4
ENST00000416569.2
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr22_-_30642728 0.24 ENST00000403987.3
LIF
leukemia inhibitory factor
chr19_+_49622646 0.24 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr9_-_4299874 0.24 ENST00000381971.3
ENST00000477901.1
GLIS3
GLIS family zinc finger 3
chr1_+_110754094 0.24 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr2_+_85981008 0.24 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr15_-_41522889 0.24 ENST00000458580.2
ENST00000314992.5
ENST00000558396.1
EXD1
exonuclease 3'-5' domain containing 1
chr1_-_155658260 0.24 ENST00000368339.5
ENST00000405763.3
ENST00000368340.5
ENST00000454523.1
ENST00000443231.1
ENST00000347088.5
ENST00000361831.5
ENST00000355499.4
YY1AP1
YY1 associated protein 1
chr4_-_168155577 0.23 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr5_-_121413974 0.23 ENST00000231004.4
LOX
lysyl oxidase
chr6_-_31864977 0.23 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr19_+_46498704 0.23 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61
coiled-coil domain containing 61
chr8_-_22550815 0.23 ENST00000317216.2
EGR3
early growth response 3
chr6_-_10413112 0.23 ENST00000465858.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr19_+_45445524 0.23 ENST00000591600.1
APOC4
apolipoprotein C-IV
chr19_+_54372877 0.23 ENST00000414489.1
MYADM
myeloid-associated differentiation marker
chr1_+_27022485 0.23 ENST00000324856.7
ARID1A
AT rich interactive domain 1A (SWI-like)
chr19_-_42758040 0.23 ENST00000593944.1
ERF
Ets2 repressor factor
chr8_-_145086922 0.23 ENST00000530478.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr10_-_103874692 0.23 ENST00000361198.5
LDB1
LIM domain binding 1
chr15_+_73344911 0.23 ENST00000560262.1
ENST00000558964.1
NEO1
neogenin 1
chr19_-_14201776 0.22 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr5_+_176873789 0.22 ENST00000323249.3
ENST00000502922.1
PRR7
proline rich 7 (synaptic)
chr6_-_29600559 0.22 ENST00000476670.1
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr19_-_18314799 0.22 ENST00000481914.2
RAB3A
RAB3A, member RAS oncogene family
chr15_+_43885799 0.22 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr14_-_21562648 0.22 ENST00000555270.1
ZNF219
zinc finger protein 219
chr19_-_49243845 0.22 ENST00000222145.4
RASIP1
Ras interacting protein 1
chr1_-_155658085 0.22 ENST00000311573.5
ENST00000438245.2
YY1AP1
YY1 associated protein 1
chr5_-_180235755 0.22 ENST00000502678.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr10_+_70980051 0.22 ENST00000354624.5
ENST00000395086.2
HKDC1
hexokinase domain containing 1
chr16_+_30935418 0.22 ENST00000338343.4
FBXL19
F-box and leucine-rich repeat protein 19
chr14_-_24804269 0.21 ENST00000310677.4
ENST00000554068.2
ENST00000559167.1
ENST00000561138.1
ADCY4
adenylate cyclase 4
chr12_-_53625958 0.21 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr16_+_69140122 0.21 ENST00000219322.3
HAS3
hyaluronan synthase 3
chr10_-_75532373 0.21 ENST00000595757.1
AC022400.2
Uncharacterized protein; cDNA FLJ44715 fis, clone BRACE3021430
chr12_+_57998400 0.21 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr2_+_136499287 0.21 ENST00000415164.1
UBXN4
UBX domain protein 4
chr17_-_39942322 0.21 ENST00000449889.1
ENST00000465293.1
JUP
junction plakoglobin
chr20_-_49639631 0.20 ENST00000424171.1
ENST00000439216.1
ENST00000371571.4
KCNG1
potassium voltage-gated channel, subfamily G, member 1
chr1_-_155658518 0.20 ENST00000404643.1
ENST00000359205.5
ENST00000407221.1
YY1AP1
YY1 associated protein 1
chr17_-_48133054 0.20 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr2_-_220408260 0.20 ENST00000373891.2
CHPF
chondroitin polymerizing factor
chr18_+_46065393 0.20 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr10_+_43932553 0.20 ENST00000456416.1
ENST00000437590.2
ENST00000451167.1
ZNF487
zinc finger protein 487
chr19_-_46272106 0.20 ENST00000560168.1
SIX5
SIX homeobox 5
chr7_+_150758304 0.20 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr20_+_44098346 0.20 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr16_+_30194916 0.20 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A
coronin, actin binding protein, 1A
chr5_+_131409476 0.20 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr6_-_29600832 0.20 ENST00000377016.4
ENST00000376977.3
ENST00000377034.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_-_150946911 0.19 ENST00000457392.1
ENST00000421609.1
CERS2
ceramide synthase 2
chr19_+_54369434 0.19 ENST00000421337.1
MYADM
myeloid-associated differentiation marker
chr6_-_32920794 0.19 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr2_+_149402009 0.19 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr16_-_4323015 0.19 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr1_+_10093188 0.19 ENST00000377153.1
UBE4B
ubiquitination factor E4B
chr9_-_130693048 0.19 ENST00000388747.4
PIP5KL1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr2_+_230787201 0.19 ENST00000283946.3
FBXO36
F-box protein 36
chr8_-_57123815 0.19 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr17_-_4852332 0.19 ENST00000572383.1
PFN1
profilin 1
chr17_+_73750699 0.19 ENST00000584939.1
ITGB4
integrin, beta 4
chr16_+_29818857 0.19 ENST00000567444.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr15_-_64338521 0.19 ENST00000457488.1
ENST00000558069.1
DAPK2
death-associated protein kinase 2
chr7_+_70229899 0.19 ENST00000443672.1
AUTS2
autism susceptibility candidate 2
chr1_+_167599330 0.19 ENST00000367854.3
ENST00000361496.3
RCSD1
RCSD domain containing 1
chr6_+_30295036 0.19 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr4_-_140223614 0.18 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr12_+_107168342 0.18 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr22_+_38382163 0.18 ENST00000333418.4
ENST00000427034.1
POLR2F
polymerase (RNA) II (DNA directed) polypeptide F
chr7_-_5465045 0.18 ENST00000399434.2
TNRC18
trinucleotide repeat containing 18
chr16_+_68729719 0.18 ENST00000569080.1
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_-_46272462 0.18 ENST00000317578.6
SIX5
SIX homeobox 5
chr19_+_18496957 0.18 ENST00000252809.3
GDF15
growth differentiation factor 15
chr19_-_14316980 0.18 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr22_+_38071615 0.18 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr17_-_40829026 0.18 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr2_-_220408430 0.18 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr9_+_109625378 0.18 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr15_+_75074915 0.18 ENST00000567123.1
ENST00000569462.1
CSK
c-src tyrosine kinase
chr1_-_223537401 0.18 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
SUSD4
sushi domain containing 4
chr6_+_31515337 0.17 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr6_+_75994755 0.17 ENST00000607799.1
RP1-234P15.4
RP1-234P15.4
chrX_-_67653291 0.17 ENST00000540071.1
OPHN1
oligophrenin 1
chr11_+_64053890 0.17 ENST00000438980.2
ENST00000313074.3
ENST00000542190.1
ENST00000541952.1
GPR137
G protein-coupled receptor 137
chr19_+_35739597 0.17 ENST00000361790.3
LSR
lipolysis stimulated lipoprotein receptor
chr12_-_122018114 0.17 ENST00000539394.1
KDM2B
lysine (K)-specific demethylase 2B
chr10_+_120967072 0.17 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr7_-_130080681 0.17 ENST00000469826.1
CEP41
centrosomal protein 41kDa
chr12_-_80084333 0.17 ENST00000552637.1
PAWR
PRKC, apoptosis, WT1, regulator
chr19_+_35739782 0.17 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr1_+_167190066 0.17 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU2F1
POU class 2 homeobox 1
chr19_+_35629702 0.17 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr1_+_36024107 0.17 ENST00000437806.1
NCDN
neurochondrin
chr1_+_32538492 0.16 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr2_+_219264466 0.16 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr5_-_73936544 0.16 ENST00000509127.2
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr15_+_91411810 0.16 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr7_+_76139741 0.16 ENST00000334348.3
ENST00000419923.2
ENST00000448265.3
ENST00000443097.2
UPK3B
uroplakin 3B
chr12_+_58005204 0.16 ENST00000286494.4
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr17_-_982198 0.16 ENST00000571945.1
ENST00000536794.2
ABR
active BCR-related
chr7_-_3083472 0.16 ENST00000356408.3
CARD11
caspase recruitment domain family, member 11
chr22_-_30642782 0.16 ENST00000249075.3
LIF
leukemia inhibitory factor
chr2_-_218867711 0.16 ENST00000446903.1
TNS1
tensin 1
chr14_-_103987679 0.16 ENST00000553610.1
CKB
creatine kinase, brain
chr6_-_41908428 0.16 ENST00000505064.1
CCND3
cyclin D3
chr6_+_149638876 0.16 ENST00000392282.1
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr9_-_14314066 0.16 ENST00000397575.3
NFIB
nuclear factor I/B
chr12_-_66275350 0.16 ENST00000536648.1
RP11-366L20.2
Uncharacterized protein
chr20_-_62258394 0.16 ENST00000370077.1
GMEB2
glucocorticoid modulatory element binding protein 2
chrX_-_153363125 0.16 ENST00000407218.1
ENST00000453960.2
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr1_+_205473720 0.16 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr2_-_75788428 0.16 ENST00000432649.1
EVA1A
eva-1 homolog A (C. elegans)
chr4_-_2264015 0.16 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr19_+_35739897 0.16 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR
lipolysis stimulated lipoprotein receptor
chr19_-_47231216 0.16 ENST00000594287.2
STRN4
striatin, calmodulin binding protein 4
chr16_-_29874211 0.15 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr15_-_49170219 0.15 ENST00000558220.1
ENST00000537958.1
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr17_-_74533734 0.15 ENST00000589342.1
CYGB
cytoglobin
chr22_-_36877371 0.15 ENST00000403313.1
TXN2
thioredoxin 2
chr5_-_149682447 0.15 ENST00000328668.7
ARSI
arylsulfatase family, member I
chr19_-_14201507 0.15 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr16_+_2079637 0.15 ENST00000561844.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr7_-_102252589 0.15 ENST00000520042.1
RASA4
RAS p21 protein activator 4
chr15_+_73344791 0.15 ENST00000261908.6
NEO1
neogenin 1
chr3_-_195619579 0.15 ENST00000428187.1
TNK2
tyrosine kinase, non-receptor, 2
chr1_+_32538520 0.15 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B
transmembrane protein 39B
chr16_-_79633799 0.15 ENST00000569649.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr11_+_67806467 0.15 ENST00000265686.3
ENST00000524598.1
ENST00000529657.1
TCIRG1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr11_-_65381643 0.15 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr1_-_151138323 0.15 ENST00000368908.5
LYSMD1
LysM, putative peptidoglycan-binding, domain containing 1
chr1_+_27022839 0.15 ENST00000457599.2
ARID1A
AT rich interactive domain 1A (SWI-like)
chr9_-_139940608 0.15 ENST00000371601.4
NPDC1
neural proliferation, differentiation and control, 1
chr1_-_155948890 0.15 ENST00000471589.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_+_205473865 0.15 ENST00000506215.1
ENST00000419301.1
CDK18
cyclin-dependent kinase 18
chr4_-_105416039 0.14 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr18_-_72264805 0.14 ENST00000577806.1
LINC00909
long intergenic non-protein coding RNA 909
chr12_-_53893399 0.14 ENST00000267079.2
MAP3K12
mitogen-activated protein kinase kinase kinase 12
chr10_-_5541525 0.14 ENST00000380332.3
CALML5
calmodulin-like 5

Network of associatons between targets according to the STRING database.

First level regulatory network of GTF2I

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0052510 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.2 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.6 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.3 GO:0050975 sensory perception of touch(GO:0050975) presynaptic active zone organization(GO:1990709)
0.1 0.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.4 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.5 GO:0003404 optic vesicle morphogenesis(GO:0003404) optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.4 GO:0042412 taurine biosynthetic process(GO:0042412)
0.1 0.3 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.3 GO:0009405 pathogenesis(GO:0009405)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.1 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.3 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.5 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.1 0.3 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.1 0.2 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.4 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.2 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.3 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.2 GO:0014011 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.0 0.2 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.1 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.2 GO:0032771 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.2 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.5 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.2 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.0 GO:1900238 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 0.2 GO:0032796 uropod organization(GO:0032796)
0.0 0.1 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.0 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.2 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.0 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924) regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.0 GO:0071505 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) positive regulation of translational initiation by iron(GO:0045994)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:1901899 positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0001777 T cell homeostatic proliferation(GO:0001777)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.0 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:1990575 mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.0 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.1 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.0 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.0 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.5 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil differentiation(GO:0030222) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.1 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.2 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.4 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.0 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.0 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.0 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.0 GO:1903412 response to bile acid(GO:1903412)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.0 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.0 0.0 GO:1905026 regulation of heart looping(GO:1901207) positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.0 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.0 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.0 GO:1990764 positive regulation of platelet aggregation(GO:1901731) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.3 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.0 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.0 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.0 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:0003360 brainstem development(GO:0003360)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.2 GO:1990923 PET complex(GO:1990923)
0.1 0.2 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.9 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.0 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.6 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 0.4 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.3 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.2 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.2 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.2 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.1 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.0 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.0 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.0 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.4 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis