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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HIF1A

Z-value: 1.36

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Transcription factors associated with HIF1A

Gene Symbol Gene ID Gene Info
HIF1A
ENSG00000100644.12 hypoxia inducible factor 1 subunit alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIF1Ahg19_v2_chr14_+_62164340_621644430.777.6e-02Click!

Activity profile of HIF1A motif

Sorted Z-values of HIF1A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_100436065 1.27 ENST00000370153.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr1_+_100435535 1.18 ENST00000427993.2
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr14_+_64970427 1.09 ENST00000553583.1
ZBTB1
zinc finger and BTB domain containing 1
chr16_-_81129845 1.02 ENST00000569885.1
ENST00000566566.1
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr6_+_89791507 0.99 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr14_+_64970662 0.92 ENST00000556965.1
ENST00000554015.1
ZBTB1
zinc finger and BTB domain containing 1
chr8_+_26240414 0.81 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr8_+_6566206 0.73 ENST00000518327.1
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5
chr16_-_81129951 0.73 ENST00000315467.3
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr8_-_54755789 0.71 ENST00000359530.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr7_-_127032363 0.70 ENST00000393312.1
ZNF800
zinc finger protein 800
chr3_-_156272924 0.69 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr1_-_8939265 0.69 ENST00000489867.1
ENO1
enolase 1, (alpha)
chr13_-_45151259 0.69 ENST00000493016.1
TSC22D1
TSC22 domain family, member 1
chr14_-_54908043 0.67 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr1_+_92495528 0.63 ENST00000370383.4
EPHX4
epoxide hydrolase 4
chr14_-_24685246 0.63 ENST00000396833.2
ENST00000288087.7
MDP1
magnesium-dependent phosphatase 1
chrX_+_47077680 0.63 ENST00000522883.1
CDK16
cyclin-dependent kinase 16
chr8_+_109455830 0.62 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr11_-_73471655 0.60 ENST00000400470.2
RAB6A
RAB6A, member RAS oncogene family
chr3_-_145878954 0.55 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr8_-_97273807 0.54 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERFD1
MTERF domain containing 1
chr7_-_27170352 0.54 ENST00000428284.2
ENST00000360046.5
HOXA4
homeobox A4
chr8_-_54755459 0.54 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr17_+_17942684 0.53 ENST00000376345.3
GID4
GID complex subunit 4
chr2_+_171627597 0.53 ENST00000429172.1
ENST00000426475.1
AC007405.6
AC007405.6
chr16_+_30418910 0.52 ENST00000566625.1
ZNF771
zinc finger protein 771
chr4_-_104119528 0.52 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr10_+_120789223 0.51 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chr14_-_64010006 0.49 ENST00000555899.1
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr2_+_216946589 0.49 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chr8_-_125551278 0.48 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TATDN1
TatD DNase domain containing 1
chr2_-_220083076 0.47 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_+_232575168 0.47 ENST00000440384.1
PTMA
prothymosin, alpha
chr4_-_76649546 0.47 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr15_+_41056255 0.47 ENST00000561160.1
ENST00000559445.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr7_-_83278322 0.47 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr2_+_111878483 0.44 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr4_-_4291761 0.44 ENST00000513174.1
LYAR
Ly1 antibody reactive
chr12_+_6977323 0.44 ENST00000462761.1
TPI1
triosephosphate isomerase 1
chr2_+_170683979 0.43 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr7_+_26331541 0.43 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr2_-_40006289 0.43 ENST00000260619.6
ENST00000454352.2
THUMPD2
THUMP domain containing 2
chr14_+_23025534 0.43 ENST00000557595.1
AE000662.92
Uncharacterized protein
chr10_+_98592009 0.43 ENST00000540664.1
ENST00000371103.3
LCOR
ligand dependent nuclear receptor corepressor
chr14_+_56046990 0.42 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
KTN1
kinectin 1 (kinesin receptor)
chr9_+_88556444 0.42 ENST00000376040.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr3_+_19988736 0.41 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr5_+_61602055 0.41 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr5_+_49962495 0.41 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr19_-_17622269 0.41 ENST00000595116.1
CTD-3131K8.2
CTD-3131K8.2
chr1_+_74663896 0.40 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
FPGT
FPGT-TNNI3K
TNNI3K
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr14_-_64010046 0.40 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr12_+_28343353 0.40 ENST00000539107.1
CCDC91
coiled-coil domain containing 91
chr17_-_67323305 0.39 ENST00000392677.2
ENST00000593153.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr12_-_48213735 0.39 ENST00000417902.1
ENST00000417107.1
HDAC7
histone deacetylase 7
chr16_+_53164956 0.39 ENST00000563410.1
CHD9
chromodomain helicase DNA binding protein 9
chr16_+_66914264 0.38 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr1_+_186798073 0.38 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr2_+_173420697 0.38 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr14_-_62217779 0.38 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr7_+_72848092 0.38 ENST00000344575.3
FZD9
frizzled family receptor 9
chr10_-_93392811 0.38 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr14_-_39901618 0.37 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr1_-_220101944 0.37 ENST00000366926.3
ENST00000536992.1
SLC30A10
solute carrier family 30, member 10
chr1_-_231376836 0.36 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr6_-_153304148 0.36 ENST00000229758.3
FBXO5
F-box protein 5
chr19_-_17622684 0.36 ENST00000596643.1
CTD-3131K8.2
CTD-3131K8.2
chr5_+_61601965 0.36 ENST00000401507.3
KIF2A
kinesin heavy chain member 2A
chr7_-_127032114 0.36 ENST00000436992.1
ZNF800
zinc finger protein 800
chrX_+_24483338 0.35 ENST00000379162.4
ENST00000441463.2
PDK3
pyruvate dehydrogenase kinase, isozyme 3
chr3_+_133292759 0.35 ENST00000431519.2
CDV3
CDV3 homolog (mouse)
chr1_-_6259641 0.35 ENST00000234875.4
RPL22
ribosomal protein L22
chr7_+_26331678 0.35 ENST00000446848.2
SNX10
sorting nexin 10
chr17_+_34890807 0.34 ENST00000429467.2
ENST00000592983.1
PIGW
phosphatidylinositol glycan anchor biosynthesis, class W
chr17_+_66287628 0.34 ENST00000581639.1
ENST00000452479.2
ARSG
arylsulfatase G
chr17_+_7608511 0.34 ENST00000226091.2
EFNB3
ephrin-B3
chr9_-_94186131 0.33 ENST00000297689.3
NFIL3
nuclear factor, interleukin 3 regulated
chr9_+_4490394 0.33 ENST00000262352.3
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr4_-_54930790 0.33 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chrX_-_13956497 0.33 ENST00000398361.3
GPM6B
glycoprotein M6B
chr2_+_30370382 0.33 ENST00000402708.1
YPEL5
yippee-like 5 (Drosophila)
chr3_+_19988566 0.32 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr20_+_33464368 0.32 ENST00000484354.1
ENST00000493805.2
ENST00000473172.1
ACSS2
acyl-CoA synthetase short-chain family member 2
chr4_-_39529049 0.32 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UGDH
UDP-glucose 6-dehydrogenase
chr1_-_167522982 0.32 ENST00000370509.4
CREG1
cellular repressor of E1A-stimulated genes 1
chr14_-_77495007 0.32 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr6_-_33679452 0.32 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
UQCC2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr2_-_74648702 0.32 ENST00000518863.1
C2orf81
chromosome 2 open reading frame 81
chr10_+_23728198 0.32 ENST00000376495.3
OTUD1
OTU domain containing 1
chr4_+_91048706 0.32 ENST00000509176.1
CCSER1
coiled-coil serine-rich protein 1
chrX_-_41782683 0.31 ENST00000378163.1
ENST00000378154.1
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr7_+_86781916 0.31 ENST00000579592.1
ENST00000434534.1
DMTF1
cyclin D binding myb-like transcription factor 1
chr5_+_78532003 0.31 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr5_+_61602236 0.31 ENST00000514082.1
ENST00000407818.3
KIF2A
kinesin heavy chain member 2A
chrX_-_57163430 0.30 ENST00000374908.1
SPIN2A
spindlin family, member 2A
chr15_+_98503922 0.30 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr8_+_26434578 0.30 ENST00000493789.2
DPYSL2
dihydropyrimidinase-like 2
chr4_-_25162188 0.30 ENST00000302922.3
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr17_-_67323232 0.29 ENST00000592568.1
ENST00000392676.3
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chrX_+_105969893 0.29 ENST00000255499.2
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr7_+_100318423 0.29 ENST00000252723.2
EPO
erythropoietin
chr6_+_108882069 0.28 ENST00000406360.1
FOXO3
forkhead box O3
chr11_-_18343725 0.28 ENST00000531848.1
HPS5
Hermansky-Pudlak syndrome 5
chr15_+_76135622 0.28 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
UBE2Q2
ubiquitin-conjugating enzyme E2Q family member 2
chr6_+_64282447 0.28 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr11_-_63933504 0.28 ENST00000255681.6
MACROD1
MACRO domain containing 1
chr8_+_109455845 0.28 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr13_-_31038370 0.28 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr6_+_151773583 0.28 ENST00000545879.1
C6orf211
chromosome 6 open reading frame 211
chr6_-_109702885 0.27 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr6_-_153304697 0.27 ENST00000367241.3
FBXO5
F-box protein 5
chrX_-_57147748 0.27 ENST00000374910.3
SPIN2B
spindlin family, member 2B
chr4_-_104119488 0.27 ENST00000514974.1
CENPE
centromere protein E, 312kDa
chr4_-_39529180 0.27 ENST00000515021.1
ENST00000510490.1
ENST00000316423.6
UGDH
UDP-glucose 6-dehydrogenase
chr13_+_103451399 0.27 ENST00000257336.1
ENST00000448849.2
BIVM
basic, immunoglobulin-like variable motif containing
chr8_-_75233563 0.27 ENST00000342232.4
JPH1
junctophilin 1
chr13_+_25670268 0.26 ENST00000281589.3
PABPC3
poly(A) binding protein, cytoplasmic 3
chr3_+_49044765 0.26 ENST00000429900.2
WDR6
WD repeat domain 6
chr11_-_76155700 0.26 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr10_+_64564469 0.26 ENST00000373783.1
ADO
2-aminoethanethiol (cysteamine) dioxygenase
chr11_+_74204395 0.26 ENST00000526036.1
AP001372.2
AP001372.2
chr7_-_102985035 0.26 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr14_-_53162361 0.26 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr1_+_231376941 0.26 ENST00000436239.1
ENST00000366647.4
ENST00000366646.3
ENST00000416000.1
GNPAT
glyceronephosphate O-acyltransferase
chr3_+_25831567 0.26 ENST00000280701.3
ENST00000420173.2
OXSM
3-oxoacyl-ACP synthase, mitochondrial
chr1_+_29241027 0.25 ENST00000373797.1
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr17_-_57184260 0.25 ENST00000376149.3
ENST00000393066.3
TRIM37
tripartite motif containing 37
chr9_-_123476612 0.25 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr22_+_41777927 0.25 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr14_+_56046914 0.25 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr15_+_52311398 0.25 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr20_+_56964253 0.25 ENST00000395802.3
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr2_+_170683942 0.25 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr20_+_36661910 0.24 ENST00000373433.4
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr6_+_71377567 0.24 ENST00000422334.2
SMAP1
small ArfGAP 1
chr1_+_65613852 0.24 ENST00000327299.7
AK4
adenylate kinase 4
chr8_+_98656693 0.24 ENST00000519934.1
MTDH
metadherin
chr7_-_22396533 0.23 ENST00000344041.6
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr22_-_24181174 0.23 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr11_-_82444892 0.23 ENST00000329203.3
FAM181B
family with sequence similarity 181, member B
chr10_+_122216707 0.23 ENST00000427079.1
ENST00000541332.1
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr4_+_76649797 0.23 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chrX_-_57147902 0.23 ENST00000275988.5
ENST00000434397.1
ENST00000333933.3
ENST00000374912.5
SPIN2B
spindlin family, member 2B
chr10_-_22292675 0.22 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr14_-_81687197 0.22 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr3_+_19988885 0.22 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr14_-_88459503 0.22 ENST00000393568.4
ENST00000261304.2
GALC
galactosylceramidase
chr22_+_40390930 0.21 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr1_-_113498616 0.21 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr8_-_101734907 0.21 ENST00000318607.5
ENST00000521865.1
ENST00000520804.1
ENST00000522720.1
ENST00000521067.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr11_+_9595180 0.21 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr14_+_96968707 0.21 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA
poly(A) polymerase alpha
chr8_+_98656336 0.21 ENST00000336273.3
MTDH
metadherin
chrX_-_34675391 0.21 ENST00000275954.3
TMEM47
transmembrane protein 47
chr9_-_123476719 0.21 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr8_+_97274119 0.21 ENST00000455950.2
PTDSS1
phosphatidylserine synthase 1
chr10_-_96122682 0.20 ENST00000371361.3
NOC3L
nucleolar complex associated 3 homolog (S. cerevisiae)
chr6_+_64281906 0.20 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr3_-_49377446 0.20 ENST00000351842.4
ENST00000416417.1
ENST00000415188.1
USP4
ubiquitin specific peptidase 4 (proto-oncogene)
chr2_+_88991162 0.20 ENST00000283646.4
RPIA
ribose 5-phosphate isomerase A
chr3_-_195808952 0.19 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC
transferrin receptor
chr17_-_57184064 0.19 ENST00000262294.7
TRIM37
tripartite motif containing 37
chr3_+_63898275 0.19 ENST00000538065.1
ATXN7
ataxin 7
chr2_+_204193129 0.19 ENST00000417864.1
ABI2
abl-interactor 2
chr2_+_109745655 0.19 ENST00000418513.1
SH3RF3
SH3 domain containing ring finger 3
chr2_+_187350973 0.19 ENST00000544130.1
ZC3H15
zinc finger CCCH-type containing 15
chr5_+_49962772 0.19 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr17_+_25621102 0.19 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WSB1
WD repeat and SOCS box containing 1
chr3_+_141596371 0.19 ENST00000495216.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr6_+_87865262 0.18 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr5_+_138609441 0.18 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3
matrin 3
chr7_+_94536898 0.18 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr7_+_86781847 0.18 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
DMTF1
cyclin D binding myb-like transcription factor 1
chr1_-_113498943 0.18 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr12_-_64616019 0.18 ENST00000311915.8
ENST00000398055.3
ENST00000544871.1
C12orf66
chromosome 12 open reading frame 66
chr10_+_122216316 0.18 ENST00000398250.1
ENST00000439221.1
ENST00000398248.1
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr13_-_24463530 0.18 ENST00000382172.3
MIPEP
mitochondrial intermediate peptidase
chr8_+_75896849 0.18 ENST00000520277.1
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr2_+_28113583 0.17 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr13_-_28024681 0.17 ENST00000381116.1
ENST00000381120.3
ENST00000431572.2
MTIF3
mitochondrial translational initiation factor 3
chr17_+_45608430 0.17 ENST00000322157.4
NPEPPS
aminopeptidase puromycin sensitive
chr4_-_492891 0.17 ENST00000338977.5
ENST00000511833.2
ZNF721
zinc finger protein 721
chr5_+_174905532 0.17 ENST00000502393.1
ENST00000506963.1
SFXN1
sideroflexin 1
chr3_-_52719888 0.17 ENST00000458294.1
PBRM1
polybromo 1
chr13_-_52027134 0.17 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr10_+_75910960 0.17 ENST00000539909.1
ENST00000286621.2
ADK
adenosine kinase
chr3_-_49377499 0.17 ENST00000265560.4
USP4
ubiquitin specific peptidase 4 (proto-oncogene)
chr10_-_46089939 0.16 ENST00000453980.3
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr19_-_49137790 0.16 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr11_+_18344106 0.16 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr2_+_187350883 0.16 ENST00000337859.6
ZC3H15
zinc finger CCCH-type containing 15
chr4_+_25162253 0.16 ENST00000512921.1
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr3_-_149688896 0.16 ENST00000239940.7
PFN2
profilin 2
chr22_-_38577782 0.16 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr1_-_26233423 0.16 ENST00000357865.2
STMN1
stathmin 1
chr17_-_35969409 0.16 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chr17_-_57184170 0.16 ENST00000393065.2
TRIM37
tripartite motif containing 37
chr11_-_72853267 0.16 ENST00000409418.4
FCHSD2
FCH and double SH3 domains 2
chr2_+_204193149 0.16 ENST00000422511.2
ABI2
abl-interactor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HIF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.5 2.5 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.5 0.5 GO:0006308 DNA catabolic process(GO:0006308)
0.4 1.8 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 0.6 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.4 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.6 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.4 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.4 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
0.1 0.6 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.8 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 1.0 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.6 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.3 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.7 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.3 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.9 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.3 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.6 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.3 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.3 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 1.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.4 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) progesterone receptor signaling pathway(GO:0050847) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.7 GO:0015886 heme transport(GO:0015886)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 1.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.1 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.8 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.3 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.6 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0097327 response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.0 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.3 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0009107 lipoate metabolic process(GO:0009106) lipoate biosynthetic process(GO:0009107)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0005960 glycine cleavage complex(GO:0005960)
0.2 1.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 1.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.4 1.8 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.2 0.7 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.4 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.3 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.6 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 2.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 1.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint