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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HINFP1

Z-value: 0.25

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Transcription factors associated with HINFP1

Gene Symbol Gene ID Gene Info

Activity profile of HINFP1 motif

Sorted Z-values of HINFP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_92219337 0.14 ENST00000456502.1
ENST00000427372.1
FAM133B
family with sequence similarity 133, member B
chr1_+_42922173 0.12 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS
phosphopantothenoylcysteine synthetase
chr2_+_130939827 0.12 ENST00000409255.1
ENST00000455239.1
MZT2B
mitotic spindle organizing protein 2B
chr4_+_2043689 0.12 ENST00000382878.3
ENST00000409248.4
C4orf48
chromosome 4 open reading frame 48
chr1_+_42921761 0.11 ENST00000372562.1
PPCS
phosphopantothenoylcysteine synthetase
chr18_+_11981547 0.11 ENST00000588927.1
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr19_+_33685490 0.10 ENST00000253193.7
LRP3
low density lipoprotein receptor-related protein 3
chr10_+_22614547 0.10 ENST00000416820.1
BMI1
BMI1 polycomb ring finger oncogene
chr6_-_56707943 0.09 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr1_+_109102652 0.08 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chr9_-_94186131 0.07 ENST00000297689.3
NFIL3
nuclear factor, interleukin 3 regulated
chr2_+_130939235 0.07 ENST00000425361.1
ENST00000457492.1
MZT2B
mitotic spindle organizing protein 2B
chr6_-_168720382 0.06 ENST00000610183.1
ENST00000607983.1
ENST00000366795.3
DACT2
dishevelled-binding antagonist of beta-catenin 2
chr14_+_73704201 0.06 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr15_-_32162833 0.06 ENST00000560598.1
OTUD7A
OTU domain containing 7A
chr18_+_11981427 0.06 ENST00000269159.3
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr2_-_234763147 0.05 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP
Holliday junction recognition protein
chr13_-_22033392 0.05 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
ZDHHC20
zinc finger, DHHC-type containing 20
chr3_+_133292759 0.05 ENST00000431519.2
CDV3
CDV3 homolog (mouse)
chr4_-_2043630 0.04 ENST00000455762.1
NELFA
negative elongation factor complex member A
chr3_-_196045127 0.04 ENST00000325318.5
TCTEX1D2
Tctex1 domain containing 2
chr1_-_222886526 0.04 ENST00000541237.1
AIDA
axin interactor, dorsalization associated
chr4_+_2043777 0.03 ENST00000409860.1
C4orf48
chromosome 4 open reading frame 48
chr10_+_49514698 0.03 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr10_+_72238517 0.03 ENST00000263563.6
PALD1
phosphatase domain containing, paladin 1
chr9_-_33264676 0.03 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr22_+_27053422 0.03 ENST00000413665.1
ENST00000421151.1
ENST00000456129.1
ENST00000430080.1
MIAT
myocardial infarction associated transcript (non-protein coding)
chr2_-_234763105 0.02 ENST00000454020.1
HJURP
Holliday junction recognition protein
chr1_+_222886694 0.02 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX
BRO1 domain and CAAX motif containing
chr19_-_5680499 0.02 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chr14_+_45366518 0.02 ENST00000557112.1
C14orf28
chromosome 14 open reading frame 28
chr19_+_1524072 0.02 ENST00000454744.2
PLK5
polo-like kinase 5
chr16_+_57279248 0.01 ENST00000562023.1
ENST00000563234.1
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr19_+_4198072 0.01 ENST00000262970.5
ANKRD24
ankyrin repeat domain 24
chr7_+_1609694 0.01 ENST00000437621.2
ENST00000457484.2
PSMG3-AS1
PSMG3 antisense RNA 1 (head to head)
chr3_+_133293278 0.00 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3
CDV3 homolog (mouse)
chr1_-_62785054 0.00 ENST00000371153.4
KANK4
KN motif and ankyrin repeat domains 4
chr1_+_210111534 0.00 ENST00000422431.1
ENST00000534859.1
ENST00000399639.2
ENST00000537238.1
SYT14
synaptotagmin XIV
chr11_+_57435441 0.00 ENST00000528177.1
ZDHHC5
zinc finger, DHHC-type containing 5

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0031673 H zone(GO:0031673)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism