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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HIVEP1

Z-value: 1.52

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Transcription factors associated with HIVEP1

Gene Symbol Gene ID Gene Info
HIVEP1
ENSG00000095951.12 HIVEP zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIVEP1hg19_v2_chr6_+_12012170_12012245-0.786.5e-02Click!

Activity profile of HIVEP1 motif

Sorted Z-values of HIVEP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153066998 1.99 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr4_-_74864386 1.87 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr1_+_37940153 1.59 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr5_-_150460914 1.50 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr6_+_138188351 1.38 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr5_+_159895275 1.37 ENST00000517927.1
MIR146A
microRNA 146a
chr11_+_18287801 1.27 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr11_+_18287721 1.26 ENST00000356524.4
SAA1
serum amyloid A1
chr14_+_103589789 1.22 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr17_+_40440481 1.21 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr6_+_138188551 1.05 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_-_35873856 1.03 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr14_+_75988851 0.97 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr4_+_74702214 0.96 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr5_-_150460539 0.92 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr6_+_138188378 0.83 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_+_45504688 0.81 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr1_+_44457441 0.77 ENST00000466180.1
CCDC24
coiled-coil domain containing 24
chr3_+_177534653 0.75 ENST00000436078.1
RP11-91K9.1
RP11-91K9.1
chr17_+_77021702 0.74 ENST00000392445.2
ENST00000354124.3
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_6918064 0.70 ENST00000546760.1
ENST00000552402.1
C17orf49
chromosome 17 open reading frame 49
chr11_-_57194111 0.70 ENST00000529112.1
ENST00000529896.1
SLC43A3
solute carrier family 43, member 3
chr17_+_6918093 0.65 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr14_-_23292596 0.65 ENST00000554741.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr7_+_116595028 0.63 ENST00000397751.1
ST7-OT4
ST7 overlapping transcript 4
chr16_+_2880157 0.63 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr11_-_65314905 0.61 ENST00000527339.1
LTBP3
latent transforming growth factor beta binding protein 3
chr17_-_39093672 0.59 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr15_-_41522889 0.58 ENST00000458580.2
ENST00000314992.5
ENST00000558396.1
EXD1
exonuclease 3'-5' domain containing 1
chr6_+_33378517 0.57 ENST00000428274.1
PHF1
PHD finger protein 1
chr11_+_64052692 0.56 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chr12_-_106697974 0.56 ENST00000553039.1
CKAP4
cytoskeleton-associated protein 4
chr8_+_55466915 0.56 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr14_+_105266933 0.56 ENST00000555360.1
ZBTB42
zinc finger and BTB domain containing 42
chr11_-_125351481 0.53 ENST00000577924.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr22_-_50708781 0.52 ENST00000449719.2
ENST00000330651.6
MAPK11
mitogen-activated protein kinase 11
chr17_+_4854375 0.51 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3
enolase 3 (beta, muscle)
chr14_-_24804269 0.50 ENST00000310677.4
ENST00000554068.2
ENST00000559167.1
ENST00000561138.1
ADCY4
adenylate cyclase 4
chr1_+_44457261 0.50 ENST00000372318.3
CCDC24
coiled-coil domain containing 24
chr10_+_124739964 0.50 ENST00000406217.2
PSTK
phosphoseryl-tRNA kinase
chr17_+_6918354 0.50 ENST00000552775.1
C17orf49
chromosome 17 open reading frame 49
chr17_+_40440094 0.49 ENST00000546010.2
STAT5A
signal transducer and activator of transcription 5A
chr4_-_76944621 0.49 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr19_+_45254529 0.49 ENST00000444487.1
BCL3
B-cell CLL/lymphoma 3
chr17_-_62097927 0.47 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
ICAM2
intercellular adhesion molecule 2
chr5_+_140579162 0.47 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chr2_-_240230890 0.47 ENST00000446876.1
HDAC4
histone deacetylase 4
chr14_-_69445793 0.45 ENST00000538545.2
ENST00000394419.4
ACTN1
actinin, alpha 1
chr14_-_69446034 0.45 ENST00000193403.6
ACTN1
actinin, alpha 1
chr11_-_104480019 0.44 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr1_+_1846519 0.43 ENST00000378604.3
CALML6
calmodulin-like 6
chr6_+_29691198 0.43 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr6_+_30851205 0.43 ENST00000515881.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr1_+_67632083 0.43 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chr14_-_69445968 0.42 ENST00000438964.2
ACTN1
actinin, alpha 1
chr16_+_4666475 0.42 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr7_-_8302298 0.42 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa
chr19_-_42636543 0.41 ENST00000528894.4
ENST00000560804.2
ENST00000560558.1
ENST00000560398.1
ENST00000526816.2
POU2F2
POU class 2 homeobox 2
chr7_+_6713376 0.41 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
AC073343.1
Uncharacterized protein
chr1_-_209824643 0.40 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr7_+_100271446 0.40 ENST00000419828.1
ENST00000427895.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr3_-_119396193 0.40 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17
COX17 cytochrome c oxidase copper chaperone
chr15_+_74509530 0.40 ENST00000321288.5
CCDC33
coiled-coil domain containing 33
chr5_+_140552218 0.40 ENST00000231137.3
PCDHB7
protocadherin beta 7
chr10_+_30723105 0.38 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr7_+_6714599 0.38 ENST00000328239.7
ENST00000542006.1
AC073343.1
Uncharacterized protein
chr14_+_103243813 0.38 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr6_+_29691056 0.38 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr15_-_41408409 0.38 ENST00000361937.3
INO80
INO80 complex subunit
chr5_+_142286887 0.38 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr8_+_72755367 0.38 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr14_+_55033815 0.38 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr1_+_114522049 0.37 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr9_+_97562440 0.37 ENST00000395357.2
C9orf3
chromosome 9 open reading frame 3
chr7_+_100271355 0.37 ENST00000436220.1
ENST00000424361.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr14_+_55034599 0.36 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr17_-_18908040 0.35 ENST00000388995.6
FAM83G
family with sequence similarity 83, member G
chr12_+_52445191 0.35 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr19_-_17186229 0.35 ENST00000253669.5
ENST00000448593.2
HAUS8
HAUS augmin-like complex, subunit 8
chr19_+_4229495 0.34 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr14_+_20811766 0.34 ENST00000250416.5
ENST00000527915.1
PARP2
poly (ADP-ribose) polymerase 2
chr1_+_41174988 0.34 ENST00000372652.1
NFYC
nuclear transcription factor Y, gamma
chr17_-_6917755 0.34 ENST00000593646.1
AC040977.1
Uncharacterized protein
chr17_-_53499218 0.34 ENST00000571578.1
MMD
monocyte to macrophage differentiation-associated
chr19_+_17326141 0.34 ENST00000445667.2
ENST00000263897.5
USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr21_+_35553045 0.33 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr7_-_8302164 0.33 ENST00000447326.1
ENST00000406470.2
ICA1
islet cell autoantigen 1, 69kDa
chr3_-_161089289 0.33 ENST00000497137.1
SPTSSB
serine palmitoyltransferase, small subunit B
chrX_+_48367338 0.33 ENST00000359882.4
ENST00000537758.1
ENST00000367574.4
ENST00000355961.4
ENST00000489940.1
ENST00000361988.3
PORCN
porcupine homolog (Drosophila)
chr15_+_42066888 0.33 ENST00000510535.1
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr1_+_155051305 0.33 ENST00000368408.3
EFNA3
ephrin-A3
chr18_-_2982869 0.32 ENST00000584915.1
LPIN2
lipin 2
chrX_+_10126488 0.32 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr3_-_100565249 0.32 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr22_+_50986462 0.31 ENST00000395676.2
KLHDC7B
kelch domain containing 7B
chr1_+_156611900 0.31 ENST00000457777.2
ENST00000424639.1
BCAN
brevican
chr1_+_152691998 0.31 ENST00000368775.2
C1orf68
chromosome 1 open reading frame 68
chr11_+_64052266 0.31 ENST00000539851.1
GPR137
G protein-coupled receptor 137
chr15_-_40398812 0.31 ENST00000561360.1
BMF
Bcl2 modifying factor
chr6_-_43478239 0.31 ENST00000372441.1
LRRC73
leucine rich repeat containing 73
chr3_-_192445289 0.31 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr7_+_144015218 0.30 ENST00000408951.1
OR2A1
olfactory receptor, family 2, subfamily A, member 1
chr2_-_163175133 0.30 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr1_+_212738676 0.29 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr19_+_18496957 0.29 ENST00000252809.3
GDF15
growth differentiation factor 15
chr1_-_206671061 0.29 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr8_-_65711310 0.29 ENST00000310193.3
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr17_+_63096903 0.29 ENST00000582940.1
RP11-160O5.1
RP11-160O5.1
chr9_-_136344197 0.29 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr19_-_6591113 0.29 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr11_+_64052944 0.29 ENST00000535675.1
ENST00000543383.1
GPR137
G protein-coupled receptor 137
chr16_+_50730910 0.28 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr12_+_48722763 0.28 ENST00000335017.1
H1FNT
H1 histone family, member N, testis-specific
chr1_+_24882560 0.28 ENST00000374392.2
NCMAP
noncompact myelin associated protein
chr19_+_41869894 0.28 ENST00000413014.2
TMEM91
transmembrane protein 91
chr11_+_64052454 0.28 ENST00000539833.1
GPR137
G protein-coupled receptor 137
chr19_+_35485682 0.28 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr20_+_327668 0.28 ENST00000382291.3
ENST00000609504.1
ENST00000382285.2
NRSN2
neurensin 2
chr19_-_30199516 0.27 ENST00000591243.1
C19orf12
chromosome 19 open reading frame 12
chr15_+_74908228 0.27 ENST00000566126.1
CLK3
CDC-like kinase 3
chr14_+_20811722 0.27 ENST00000429687.3
PARP2
poly (ADP-ribose) polymerase 2
chr10_+_60272814 0.27 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr5_+_140625147 0.27 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr9_-_123691047 0.26 ENST00000373887.3
TRAF1
TNF receptor-associated factor 1
chr12_-_50101003 0.26 ENST00000550488.1
FMNL3
formin-like 3
chr2_-_27558270 0.26 ENST00000454704.1
GTF3C2
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr19_+_2270283 0.26 ENST00000588673.2
OAZ1
ornithine decarboxylase antizyme 1
chr5_+_134303591 0.26 ENST00000282611.6
CATSPER3
cation channel, sperm associated 3
chr19_-_37178284 0.26 ENST00000425254.2
ENST00000590952.1
ENST00000433232.1
AC074138.3
AC074138.3
chr22_-_29949680 0.26 ENST00000397873.2
ENST00000490103.1
THOC5
THO complex 5
chr15_+_91411810 0.26 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr3_-_46068969 0.25 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr12_-_62997214 0.25 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr6_-_13328050 0.25 ENST00000420456.1
TBC1D7
TBC1 domain family, member 7
chr2_-_61108449 0.25 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr2_-_74781061 0.25 ENST00000264094.3
ENST00000393937.2
ENST00000409986.1
LOXL3
lysyl oxidase-like 3
chr4_+_77177512 0.25 ENST00000606246.1
FAM47E
family with sequence similarity 47, member E
chr11_+_64053005 0.25 ENST00000538032.1
GPR137
G protein-coupled receptor 137
chr11_-_67276100 0.25 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr17_+_35306175 0.25 ENST00000225402.5
AATF
apoptosis antagonizing transcription factor
chr2_-_216300784 0.25 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr14_+_55034330 0.25 ENST00000251091.5
SAMD4A
sterile alpha motif domain containing 4A
chr19_-_43835582 0.24 ENST00000595748.1
CTC-490G23.2
CTC-490G23.2
chr6_+_139117251 0.24 ENST00000401414.3
ECT2L
epithelial cell transforming sequence 2 oncogene-like
chr6_-_31508304 0.24 ENST00000376177.2
DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr5_+_53751445 0.24 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr5_+_127039075 0.24 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr5_-_149792295 0.24 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr12_+_57623907 0.24 ENST00000553529.1
ENST00000554310.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr6_-_33256664 0.24 ENST00000444176.1
WDR46
WD repeat domain 46
chr1_+_15272271 0.24 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr17_-_9479128 0.24 ENST00000574431.1
STX8
syntaxin 8
chr19_+_51897742 0.23 ENST00000600765.1
CTD-2616J11.14
CTD-2616J11.14
chr19_-_51466681 0.23 ENST00000456750.2
KLK6
kallikrein-related peptidase 6
chr15_+_57891609 0.23 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr3_+_9774164 0.23 ENST00000426583.1
BRPF1
bromodomain and PHD finger containing, 1
chr2_-_113999260 0.23 ENST00000468980.2
PAX8
paired box 8
chr19_+_41256764 0.23 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr15_+_59730348 0.23 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr1_+_110453203 0.23 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr6_-_33290580 0.22 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
DAXX
death-domain associated protein
chr6_-_31324943 0.22 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr1_-_21616690 0.22 ENST00000264205.6
ECE1
endothelin converting enzyme 1
chr12_+_10365082 0.22 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr2_-_220252530 0.22 ENST00000521459.1
DNPEP
aspartyl aminopeptidase
chr12_+_112451222 0.22 ENST00000552052.1
ERP29
endoplasmic reticulum protein 29
chr15_+_74908147 0.22 ENST00000568139.1
ENST00000563297.1
ENST00000568488.1
ENST00000352989.5
ENST00000348245.3
CLK3
CDC-like kinase 3
chr6_-_112115074 0.22 ENST00000368667.2
FYN
FYN oncogene related to SRC, FGR, YES
chr15_+_91427726 0.22 ENST00000452243.1
FES
feline sarcoma oncogene
chr6_-_6711235 0.22 ENST00000432823.2
RP1-80N2.2
RP1-80N2.2
chr3_+_187086120 0.21 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr22_-_29949634 0.21 ENST00000397872.1
ENST00000397871.1
ENST00000440771.1
THOC5
THO complex 5
chr16_-_85969774 0.21 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr7_-_22259845 0.21 ENST00000420196.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr9_-_112970436 0.21 ENST00000400613.4
C9orf152
chromosome 9 open reading frame 152
chr18_-_72920372 0.21 ENST00000581620.1
ENST00000582437.1
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr7_+_18548878 0.20 ENST00000456174.2
HDAC9
histone deacetylase 9
chr16_+_88772866 0.20 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
CTU2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr17_-_1389228 0.20 ENST00000438665.2
MYO1C
myosin IC
chr2_+_74120094 0.20 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2
actin, gamma 2, smooth muscle, enteric
chr21_+_34775698 0.20 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr6_-_32908792 0.20 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chrX_+_47444613 0.20 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr7_-_87849340 0.20 ENST00000419179.1
ENST00000265729.2
SRI
sorcin
chr17_+_7461580 0.20 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr8_+_27168988 0.20 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr17_-_53499310 0.19 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr19_-_51522955 0.19 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr19_-_5978090 0.19 ENST00000592621.1
ENST00000034275.8
ENST00000591092.1
ENST00000591333.1
ENST00000590623.1
ENST00000439268.2
ENST00000587159.1
RANBP3
RAN binding protein 3
chr16_+_75032901 0.19 ENST00000335325.4
ENST00000320619.6
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr13_-_46756351 0.19 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_24664540 0.19 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
TM9SF1
transmembrane 9 superfamily member 1
chrX_+_9935392 0.19 ENST00000445307.2
AC002365.1
Homo sapiens uncharacterized LOC100288814 (LOC100288814), mRNA.
chr19_-_44324750 0.19 ENST00000594049.1
ENST00000414615.2
LYPD5
LY6/PLAUR domain containing 5
chr12_+_57624059 0.18 ENST00000557427.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr14_-_69262916 0.18 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr4_-_122085469 0.18 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr19_-_4831701 0.18 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr6_-_44281043 0.18 ENST00000244571.4
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr5_-_58652788 0.18 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific

Network of associatons between targets according to the STRING database.

First level regulatory network of HIVEP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of CD40 signaling pathway(GO:2000349)
0.5 1.6 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.5 2.4 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 1.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 1.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2 0.5 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.2 0.6 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 3.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.6 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.2 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.3 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.7 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.5 GO:1903974 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.1 0.6 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 0.9 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.5 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 2.9 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 0.9 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.3 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.4 GO:0038155 positive regulation of activation of Janus kinase activity(GO:0010536) interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.2 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 0.7 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.2 GO:0072304 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.2 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 1.2 GO:0051601 exocyst localization(GO:0051601)
0.1 0.3 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.9 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.7 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:0061386 noradrenergic neuron differentiation(GO:0003357) closure of optic fissure(GO:0061386)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 0.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 1.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.1 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.2 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.0 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.0 0.1 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.3 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0021644 vagus nerve morphogenesis(GO:0021644)
0.0 0.3 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.8 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.4 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 2.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.3 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0035137 embryonic hindlimb morphogenesis(GO:0035116) hindlimb morphogenesis(GO:0035137)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:1904339 superior temporal gyrus development(GO:0071109) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.5 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.2 GO:0048298 regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0051709 regulation of killing of cells of other organism(GO:0051709) positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0014010 Schwann cell proliferation(GO:0014010)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.2 GO:0009799 determination of left/right symmetry(GO:0007368) specification of symmetry(GO:0009799) determination of bilateral symmetry(GO:0009855)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.5 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.6 GO:1990923 PET complex(GO:1990923)
0.1 0.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 0.9 GO:0070552 BRISC complex(GO:0070552)
0.1 0.4 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 2.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.1 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.3 GO:0005916 fascia adherens(GO:0005916)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 1.2 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.0 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 3.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 3.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.6 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.8 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.3 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.3 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.9 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.4 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 1.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.4 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.0 2.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 1.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 1.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.0 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266) porin activity(GO:0015288)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 7.6 PID CD40 PATHWAY CD40/CD40L signaling
0.1 2.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 4.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide