Project

NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for HMGA2

Z-value: 0.51

Motif logo

logo of

Transcription factors associated with HMGA2

Gene Symbol Gene ID Gene Info
HMGA2
ENSG00000149948.9 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA2hg19_v2_chr12_+_66218212_66218244-0.901.4e-02Click!

Activity profile of HMGA2 motif

Sorted Z-values of HMGA2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_65996599 0.53 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr14_+_50291993 0.21 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr1_-_67600639 0.19 ENST00000544837.1
ENST00000603691.1
C1orf141
chromosome 1 open reading frame 141
chr3_+_121774202 0.18 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr6_+_116892641 0.18 ENST00000487832.2
ENST00000518117.1
RWDD1
RWD domain containing 1
chr18_-_14132422 0.17 ENST00000589498.1
ENST00000590202.1
ZNF519
zinc finger protein 519
chr1_+_227751231 0.16 ENST00000343776.5
ENST00000608949.1
ENST00000397097.3
ZNF678
zinc finger protein 678
chr22_+_22676808 0.15 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr19_+_44455368 0.14 ENST00000591168.1
ENST00000587682.1
ENST00000251269.5
ZNF221
zinc finger protein 221
chr16_+_66442411 0.14 ENST00000499966.1
LINC00920
long intergenic non-protein coding RNA 920
chr1_+_227751281 0.13 ENST00000440339.1
ZNF678
zinc finger protein 678
chr12_-_10573149 0.12 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
KLRC3
killer cell lectin-like receptor subfamily C, member 3
chr6_+_111580508 0.12 ENST00000368847.4
KIAA1919
KIAA1919
chr13_+_50656307 0.11 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr11_-_18063973 0.10 ENST00000528338.1
TPH1
tryptophan hydroxylase 1
chr4_+_25378912 0.10 ENST00000510092.1
ENST00000505991.1
ANAPC4
anaphase promoting complex subunit 4
chr6_-_136571400 0.10 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
MTFR2
mitochondrial fission regulator 2
chr14_-_94759595 0.10 ENST00000261994.4
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr1_+_2487800 0.10 ENST00000355716.4
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr3_-_123680246 0.10 ENST00000488653.2
CCDC14
coiled-coil domain containing 14
chr2_+_120436733 0.09 ENST00000401466.1
ENST00000424086.1
ENST00000272521.6
TMEM177
transmembrane protein 177
chr2_-_287299 0.09 ENST00000405290.1
FAM150B
family with sequence similarity 150, member B
chr2_+_170683979 0.09 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr5_+_67485704 0.09 ENST00000520762.1
RP11-404L6.2
Uncharacterized protein
chr1_+_196621156 0.09 ENST00000359637.2
CFH
complement factor H
chr16_+_53483983 0.09 ENST00000544545.1
RBL2
retinoblastoma-like 2 (p130)
chr1_+_179263308 0.09 ENST00000426956.1
SOAT1
sterol O-acyltransferase 1
chr1_+_144989309 0.08 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr2_+_120436760 0.08 ENST00000445518.1
ENST00000409951.1
TMEM177
transmembrane protein 177
chr10_-_62332357 0.08 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_196621002 0.08 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr20_+_54967663 0.08 ENST00000452950.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr3_+_106959530 0.08 ENST00000466734.1
ENST00000463143.1
ENST00000490441.1
LINC00883
long intergenic non-protein coding RNA 883
chr1_+_55464600 0.08 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr6_+_123110302 0.08 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr4_+_40058411 0.08 ENST00000261435.6
ENST00000515550.1
N4BP2
NEDD4 binding protein 2
chr14_+_45553296 0.08 ENST00000355765.6
ENST00000553605.1
PRPF39
pre-mRNA processing factor 39
chr9_-_115480303 0.07 ENST00000374234.1
ENST00000374238.1
ENST00000374236.1
ENST00000374242.4
INIP
INTS3 and NABP interacting protein
chr3_+_186501336 0.07 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
EIF4A2
eukaryotic translation initiation factor 4A2
chr13_+_51483814 0.07 ENST00000336617.3
ENST00000422660.1
RNASEH2B
ribonuclease H2, subunit B
chr4_-_299110 0.07 ENST00000419098.1
ZNF732
zinc finger protein 732
chr2_+_170683942 0.07 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr6_-_127664736 0.07 ENST00000368291.2
ENST00000309620.9
ENST00000454859.3
ECHDC1
enoyl CoA hydratase domain containing 1
chr11_+_73661364 0.06 ENST00000339764.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr2_-_183387064 0.06 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr5_+_36608422 0.06 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr21_+_38792602 0.06 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr15_-_83018198 0.06 ENST00000557886.1
RP13-996F3.4
golgin A6 family-like 19
chr12_-_122751002 0.06 ENST00000267199.4
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr2_-_287320 0.06 ENST00000401503.1
FAM150B
family with sequence similarity 150, member B
chr10_-_5046042 0.06 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chrX_-_7895755 0.05 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
PNPLA4
patatin-like phospholipase domain containing 4
chr15_-_32747835 0.05 ENST00000509311.2
ENST00000414865.2
GOLGA8O
golgin A8 family, member O
chr12_-_10324716 0.05 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr9_+_42704004 0.05 ENST00000457288.1
CBWD7
COBW domain containing 7
chr15_+_84904525 0.05 ENST00000510439.2
GOLGA6L4
golgin A6 family-like 4
chr18_+_11851383 0.05 ENST00000526991.2
CHMP1B
charged multivesicular body protein 1B
chr15_-_70994612 0.05 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr6_-_127664683 0.05 ENST00000528402.1
ENST00000454591.2
ECHDC1
enoyl CoA hydratase domain containing 1
chr15_-_82939157 0.05 ENST00000559949.1
RP13-996F3.5
golgin A6 family-like 18
chr1_+_64014588 0.04 ENST00000371086.2
ENST00000340052.3
DLEU2L
deleted in lymphocytic leukemia 2-like
chr19_-_38146289 0.04 ENST00000392144.1
ENST00000591444.1
ENST00000351218.2
ENST00000587809.1
ZFP30
ZFP30 zinc finger protein
chr10_+_96305535 0.04 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
HELLS
helicase, lymphoid-specific
chr17_-_30186328 0.04 ENST00000302362.6
COPRS
coordinator of PRMT5, differentiation stimulator
chr20_+_46130671 0.04 ENST00000371998.3
ENST00000371997.3
NCOA3
nuclear receptor coactivator 3
chr12_+_21207503 0.04 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr7_-_102985035 0.04 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr15_+_83098710 0.04 ENST00000561062.1
ENST00000358583.3
GOLGA6L9
golgin A6 family-like 20
chr20_+_46130619 0.04 ENST00000372004.3
NCOA3
nuclear receptor coactivator 3
chrX_+_2670153 0.04 ENST00000509484.2
XG
Xg blood group
chr4_+_184826418 0.04 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr1_+_2487402 0.04 ENST00000451778.1
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr9_+_104296122 0.04 ENST00000389120.3
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr11_-_130786400 0.04 ENST00000265909.4
SNX19
sorting nexin 19
chr10_+_90484301 0.03 ENST00000404190.1
LIPK
lipase, family member K
chr18_-_29340827 0.03 ENST00000269205.5
SLC25A52
solute carrier family 25, member 52
chrX_+_117480036 0.03 ENST00000371822.5
ENST00000254029.3
ENST00000371825.3
WDR44
WD repeat domain 44
chr9_+_2157655 0.03 ENST00000452193.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_+_82722225 0.03 ENST00000300515.8
GOLGA6L9
golgin A6 family-like 9
chr14_-_94759361 0.03 ENST00000393096.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr2_+_177134201 0.03 ENST00000452865.1
MTX2
metaxin 2
chrX_-_135962876 0.03 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chrX_+_2924654 0.03 ENST00000381130.2
ARSH
arylsulfatase family, member H
chr6_-_160209471 0.03 ENST00000539948.1
TCP1
t-complex 1
chr15_-_74659978 0.03 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr19_-_43099070 0.03 ENST00000244336.5
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr10_-_36813162 0.03 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr2_+_235887329 0.03 ENST00000409212.1
ENST00000344528.4
ENST00000444916.1
SH3BP4
SH3-domain binding protein 4
chr1_-_76398077 0.03 ENST00000284142.6
ASB17
ankyrin repeat and SOCS box containing 17
chrX_-_77150985 0.03 ENST00000358075.6
MAGT1
magnesium transporter 1
chr12_+_18414446 0.02 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr5_+_150827143 0.02 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr14_-_94759408 0.02 ENST00000554723.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr20_+_46130601 0.02 ENST00000341724.6
NCOA3
nuclear receptor coactivator 3
chr2_+_220144052 0.02 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chrX_-_7895479 0.02 ENST00000381042.4
PNPLA4
patatin-like phospholipase domain containing 4
chr6_+_31887761 0.02 ENST00000413154.1
C2
complement component 2
chr7_-_102985288 0.01 ENST00000379263.3
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr15_+_88120158 0.01 ENST00000560153.1
LINC00052
long intergenic non-protein coding RNA 52
chr11_-_130786333 0.01 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19
sorting nexin 19
chrX_+_2670066 0.01 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
XG
Xg blood group
chr2_+_172544182 0.01 ENST00000409197.1
ENST00000456808.1
ENST00000409317.1
ENST00000409773.1
ENST00000411953.1
ENST00000409453.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr14_+_37641012 0.01 ENST00000556667.1
SLC25A21-AS1
SLC25A21 antisense RNA 1
chr8_-_105479270 0.01 ENST00000521573.2
ENST00000351513.2
DPYS
dihydropyrimidinase
chr6_-_52926539 0.01 ENST00000350082.5
ENST00000356971.3
ICK
intestinal cell (MAK-like) kinase
chr2_-_183387430 0.01 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr17_-_76220740 0.01 ENST00000600484.1
AC087645.1
Uncharacterized protein
chr2_+_39117010 0.00 ENST00000409978.1
ARHGEF33
Rho guanine nucleotide exchange factor (GEF) 33
chr15_+_58702742 0.00 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr7_+_80275953 0.00 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr10_-_101673782 0.00 ENST00000422692.1
DNMBP
dynamin binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.2 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.0 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.0 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)