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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HMX1

Z-value: 1.19

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Transcription factors associated with HMX1

Gene Symbol Gene ID Gene Info
HMX1
ENSG00000215612.5 H6 family homeobox 1

Activity profile of HMX1 motif

Sorted Z-values of HMX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_18923655 0.99 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
PRODH
proline dehydrogenase (oxidase) 1
chr11_+_60699222 0.64 ENST00000536409.1
TMEM132A
transmembrane protein 132A
chr2_-_192016276 0.55 ENST00000413064.1
STAT4
signal transducer and activator of transcription 4
chr5_-_81046904 0.52 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr19_+_5904866 0.51 ENST00000339485.3
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chr19_-_1401486 0.50 ENST00000252288.2
ENST00000447102.3
GAMT
guanidinoacetate N-methyltransferase
chr2_+_130939235 0.48 ENST00000425361.1
ENST00000457492.1
MZT2B
mitotic spindle organizing protein 2B
chr15_-_75748143 0.48 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3A
SIN3 transcription regulator family member A
chr2_-_102003987 0.48 ENST00000324768.5
CREG2
cellular repressor of E1A-stimulated genes 2
chr9_-_74525847 0.46 ENST00000377041.2
ABHD17B
abhydrolase domain containing 17B
chr2_+_27346666 0.44 ENST00000316470.4
ENST00000416071.1
ABHD1
abhydrolase domain containing 1
chr19_+_41305627 0.42 ENST00000593525.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chrX_+_13587712 0.42 ENST00000361306.1
ENST00000380602.3
EGFL6
EGF-like-domain, multiple 6
chr17_+_38465441 0.42 ENST00000577646.1
ENST00000254066.5
RARA
retinoic acid receptor, alpha
chr5_-_81046922 0.41 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr19_+_55987998 0.41 ENST00000591164.1
ZNF628
zinc finger protein 628
chr12_+_7060508 0.41 ENST00000541698.1
ENST00000542462.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr20_+_49348109 0.41 ENST00000396039.1
PARD6B
par-6 family cell polarity regulator beta
chr13_+_42031679 0.40 ENST00000379359.3
RGCC
regulator of cell cycle
chr11_+_826136 0.39 ENST00000528315.1
ENST00000533803.1
EFCAB4A
EF-hand calcium binding domain 4A
chrX_-_107019181 0.39 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22D3
TSC22 domain family, member 3
chr11_-_65308082 0.38 ENST00000532661.1
LTBP3
latent transforming growth factor beta binding protein 3
chr5_-_24645078 0.38 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr19_+_41305612 0.37 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr11_+_66624527 0.36 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr2_-_192015697 0.35 ENST00000409995.1
STAT4
signal transducer and activator of transcription 4
chr11_+_43702322 0.35 ENST00000395700.4
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr21_+_46875395 0.34 ENST00000355480.5
COL18A1
collagen, type XVIII, alpha 1
chr3_+_127391769 0.33 ENST00000393363.3
ENST00000232744.8
ENST00000453791.2
ABTB1
ankyrin repeat and BTB (POZ) domain containing 1
chr21_+_46875424 0.33 ENST00000359759.4
COL18A1
collagen, type XVIII, alpha 1
chr18_+_11981547 0.32 ENST00000588927.1
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr3_+_151986709 0.31 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr4_-_11430221 0.31 ENST00000514690.1
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr2_+_46769798 0.30 ENST00000238738.4
RHOQ
ras homolog family member Q
chr9_-_74525658 0.30 ENST00000333421.6
ABHD17B
abhydrolase domain containing 17B
chr20_+_44098385 0.29 ENST00000217425.5
ENST00000339946.3
WFDC2
WAP four-disulfide core domain 2
chr19_+_41305740 0.29 ENST00000596517.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr18_+_11981427 0.29 ENST00000269159.3
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr5_-_81046841 0.28 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr11_+_105948216 0.28 ENST00000278618.4
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr8_+_145691411 0.28 ENST00000301332.2
KIFC2
kinesin family member C2
chr12_+_7060414 0.28 ENST00000538715.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr20_+_44098346 0.28 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr4_-_2420335 0.28 ENST00000503000.1
ZFYVE28
zinc finger, FYVE domain containing 28
chr18_-_45935663 0.26 ENST00000589194.1
ENST00000591279.1
ENST00000590855.1
ENST00000587107.1
ENST00000588970.1
ENST00000586525.1
ENST00000592387.1
ENST00000590800.1
ZBTB7C
zinc finger and BTB domain containing 7C
chr7_-_105332084 0.26 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr6_-_56716686 0.25 ENST00000520645.1
DST
dystonin
chrX_-_153744507 0.25 ENST00000442929.1
ENST00000426266.1
ENST00000359889.5
ENST00000369641.3
ENST00000447601.2
ENST00000434658.2
FAM3A
family with sequence similarity 3, member A
chr4_+_1795508 0.25 ENST00000260795.2
ENST00000352904.1
FGFR3
fibroblast growth factor receptor 3
chr9_-_100000957 0.25 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
RP11-498P14.5
chr9_-_131940526 0.25 ENST00000372491.2
IER5L
immediate early response 5-like
chr11_-_559377 0.24 ENST00000486629.1
C11orf35
chromosome 11 open reading frame 35
chr6_+_2245982 0.24 ENST00000530346.1
ENST00000524770.1
ENST00000532124.1
ENST00000531092.1
ENST00000456943.2
ENST00000529893.1
GMDS-AS1
GMDS antisense RNA 1 (head to head)
chr10_+_99258625 0.24 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr14_-_36789783 0.24 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MBIP
MAP3K12 binding inhibitory protein 1
chr8_-_17270809 0.24 ENST00000180173.5
ENST00000521857.1
MTMR7
myotubularin related protein 7
chr5_+_139027877 0.23 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr16_-_70712229 0.23 ENST00000562883.2
MTSS1L
metastasis suppressor 1-like
chr16_+_28996364 0.23 ENST00000564277.1
LAT
linker for activation of T cells
chr12_-_7077125 0.23 ENST00000545555.2
PHB2
prohibitin 2
chr6_+_126277842 0.23 ENST00000229633.5
HINT3
histidine triad nucleotide binding protein 3
chr4_+_83956312 0.23 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr17_-_15244894 0.22 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
TEKT3
tektin 3
chr16_+_83986827 0.22 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr19_-_45579762 0.22 ENST00000303809.2
ZNF296
zinc finger protein 296
chr11_+_118478313 0.22 ENST00000356063.5
PHLDB1
pleckstrin homology-like domain, family B, member 1
chrX_+_22050546 0.22 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr1_+_174846570 0.21 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr12_-_42631529 0.21 ENST00000548917.1
YAF2
YY1 associated factor 2
chr13_-_76111945 0.21 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr3_-_107941209 0.21 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr22_-_39268192 0.21 ENST00000216083.6
CBX6
chromobox homolog 6
chr16_+_19535133 0.21 ENST00000396212.2
ENST00000381396.5
CCP110
centriolar coiled coil protein 110kDa
chr2_-_220435963 0.21 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr12_-_54778444 0.20 ENST00000551771.1
ZNF385A
zinc finger protein 385A
chr7_-_16844611 0.20 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chr1_-_28241024 0.20 ENST00000313433.7
ENST00000444045.1
RPA2
replication protein A2, 32kDa
chrX_-_153744434 0.19 ENST00000369643.1
ENST00000393572.1
FAM3A
family with sequence similarity 3, member A
chr6_+_41606176 0.19 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr19_+_41305330 0.19 ENST00000593972.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr3_+_69788576 0.19 ENST00000352241.4
ENST00000448226.2
MITF
microphthalmia-associated transcription factor
chr17_+_79679299 0.19 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr1_+_53480598 0.19 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr9_-_139948487 0.19 ENST00000355097.2
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr9_-_140082983 0.18 ENST00000323927.2
ANAPC2
anaphase promoting complex subunit 2
chr1_-_46598371 0.18 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr4_+_86396265 0.18 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr19_-_46285646 0.18 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr21_-_42880075 0.18 ENST00000332149.5
TMPRSS2
transmembrane protease, serine 2
chr1_+_6052700 0.18 ENST00000378092.1
ENST00000445501.1
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr17_-_74533734 0.18 ENST00000589342.1
CYGB
cytoglobin
chr8_+_38854368 0.18 ENST00000466936.1
ADAM9
ADAM metallopeptidase domain 9
chr3_-_138553779 0.17 ENST00000461451.1
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr11_-_17035943 0.17 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr14_+_23776024 0.17 ENST00000553781.1
ENST00000556100.1
ENST00000557236.1
ENST00000557579.1
BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 readthrough
BCL2-like 2
chr8_-_38854332 0.17 ENST00000520152.1
ENST00000522142.1
TM2D2
TM2 domain containing 2
chr16_-_70713928 0.17 ENST00000576338.1
MTSS1L
metastasis suppressor 1-like
chr12_+_57482665 0.16 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr6_-_42418999 0.16 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr8_-_75233563 0.16 ENST00000342232.4
JPH1
junctophilin 1
chr22_-_39268308 0.16 ENST00000407418.3
CBX6
chromobox homolog 6
chr2_-_129076151 0.16 ENST00000259241.6
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr16_+_28996416 0.16 ENST00000395456.2
ENST00000454369.2
LAT
linker for activation of T cells
chr6_-_33679452 0.16 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
UQCC2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr12_+_57482877 0.16 ENST00000342556.6
ENST00000357680.4
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr1_-_53387386 0.16 ENST00000467988.1
ENST00000358358.5
ENST00000371522.4
ECHDC2
enoyl CoA hydratase domain containing 2
chr12_+_53440753 0.16 ENST00000379902.3
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr19_-_14316980 0.16 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr21_-_40685477 0.15 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr6_-_8102714 0.15 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr16_+_28996572 0.15 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
LAT
linker for activation of T cells
chr3_-_52312337 0.15 ENST00000469000.1
WDR82
WD repeat domain 82
chr9_-_130617029 0.15 ENST00000373203.4
ENG
endoglin
chr12_+_32552451 0.15 ENST00000534526.2
FGD4
FYVE, RhoGEF and PH domain containing 4
chr21_-_43187231 0.15 ENST00000332512.3
ENST00000352483.2
RIPK4
receptor-interacting serine-threonine kinase 4
chr1_-_109940550 0.15 ENST00000256637.6
SORT1
sortilin 1
chr5_+_112043186 0.15 ENST00000509732.1
ENST00000457016.1
ENST00000507379.1
APC
adenomatous polyposis coli
chr1_-_46598284 0.15 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr2_-_69870747 0.15 ENST00000409068.1
AAK1
AP2 associated kinase 1
chr21_-_42879909 0.15 ENST00000458356.1
ENST00000398585.3
ENST00000424093.1
TMPRSS2
transmembrane protease, serine 2
chr4_-_2420357 0.15 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
ZFYVE28
zinc finger, FYVE domain containing 28
chr19_-_46285736 0.14 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr2_-_175462934 0.14 ENST00000392546.2
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family, member 1
chr1_-_54405773 0.14 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr2_-_27712583 0.14 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr17_+_79679369 0.14 ENST00000350690.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr9_-_130487143 0.14 ENST00000419060.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr12_-_16035195 0.14 ENST00000535752.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr4_+_91048706 0.14 ENST00000509176.1
CCSER1
coiled-coil serine-rich protein 1
chrX_+_47444613 0.14 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chrX_-_153599578 0.14 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr9_-_130616915 0.14 ENST00000344849.3
ENG
endoglin
chr19_-_52227221 0.14 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr17_+_74381343 0.14 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr11_-_105948129 0.14 ENST00000526793.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr16_+_55690205 0.14 ENST00000379906.2
SLC6A2
solute carrier family 6 (neurotransmitter transporter), member 2
chr1_-_32229523 0.13 ENST00000398547.1
ENST00000373655.2
ENST00000373658.3
ENST00000257070.4
BAI2
brain-specific angiogenesis inhibitor 2
chr1_-_53387352 0.13 ENST00000541281.1
ECHDC2
enoyl CoA hydratase domain containing 2
chr11_-_105948040 0.13 ENST00000534815.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr2_-_20550416 0.13 ENST00000403432.1
ENST00000424110.1
PUM2
pumilio RNA-binding family member 2
chr3_-_142166796 0.13 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chr14_-_36789865 0.13 ENST00000416007.4
MBIP
MAP3K12 binding inhibitory protein 1
chr12_+_7060432 0.13 ENST00000318974.9
ENST00000456013.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr17_+_79990058 0.13 ENST00000584341.1
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr14_+_63671105 0.13 ENST00000316754.3
RHOJ
ras homolog family member J
chr15_-_79103757 0.13 ENST00000388820.4
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr12_-_54778471 0.12 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A
zinc finger protein 385A
chr16_-_776431 0.12 ENST00000293889.6
CCDC78
coiled-coil domain containing 78
chr2_-_69870835 0.12 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr4_-_140005341 0.12 ENST00000379549.2
ENST00000512627.1
ELF2
E74-like factor 2 (ets domain transcription factor)
chr17_+_74722912 0.12 ENST00000589977.1
ENST00000591571.1
ENST00000592849.1
ENST00000586738.1
ENST00000588783.1
ENST00000588563.1
ENST00000586752.1
ENST00000588302.1
ENST00000590964.1
ENST00000341249.6
ENST00000588822.1
METTL23
methyltransferase like 23
chr3_+_50192457 0.12 ENST00000414301.1
ENST00000450338.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_115259337 0.12 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr1_-_62190793 0.12 ENST00000371177.2
ENST00000606498.1
TM2D1
TM2 domain containing 1
chr2_-_20550382 0.12 ENST00000536417.1
PUM2
pumilio RNA-binding family member 2
chr11_-_67275542 0.12 ENST00000531506.1
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr8_-_67525473 0.12 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr20_+_36661910 0.12 ENST00000373433.4
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr19_-_19006920 0.12 ENST00000429504.2
ENST00000427170.2
CERS1
ceramide synthase 1
chr7_-_559853 0.12 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr15_+_81489213 0.12 ENST00000559383.1
ENST00000394660.2
IL16
interleukin 16
chr1_+_202431859 0.12 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr10_-_82049424 0.12 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr9_+_100000717 0.11 ENST00000375205.2
ENST00000357054.1
ENST00000395220.1
ENST00000375202.2
ENST00000411667.2
CCDC180
coiled-coil domain containing 180
chr12_+_26274917 0.11 ENST00000538142.1
SSPN
sarcospan
chr3_-_142166904 0.11 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr4_-_186733363 0.11 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr4_-_140005443 0.11 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2
E74-like factor 2 (ets domain transcription factor)
chr16_-_67190152 0.11 ENST00000486556.1
TRADD
TNFRSF1A-associated via death domain
chr16_+_55690002 0.11 ENST00000414754.3
SLC6A2
solute carrier family 6 (neurotransmitter transporter), member 2
chr7_+_130131907 0.11 ENST00000223215.4
ENST00000437945.1
MEST
mesoderm specific transcript
chr16_+_85645007 0.11 ENST00000405402.2
GSE1
Gse1 coiled-coil protein
chr9_+_131644398 0.11 ENST00000372599.3
LRRC8A
leucine rich repeat containing 8 family, member A
chr2_+_203499901 0.11 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr3_-_18466787 0.11 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr1_+_203444887 0.11 ENST00000343110.2
PRELP
proline/arginine-rich end leucine-rich repeat protein
chr1_+_38512799 0.11 ENST00000432922.1
ENST00000428151.1
RP5-884C9.2
RP5-884C9.2
chr13_+_37574678 0.11 ENST00000389704.3
EXOSC8
exosome component 8
chr16_+_50280020 0.11 ENST00000564965.1
ADCY7
adenylate cyclase 7
chr6_-_30523865 0.11 ENST00000433809.1
GNL1
guanine nucleotide binding protein-like 1
chr3_+_50192537 0.10 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr20_+_49348081 0.10 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr5_-_37371163 0.10 ENST00000513532.1
NUP155
nucleoporin 155kDa
chr5_+_95998673 0.10 ENST00000514845.1
CAST
calpastatin
chr3_-_142166846 0.10 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr22_+_47070490 0.10 ENST00000408031.1
GRAMD4
GRAM domain containing 4
chr14_+_23776167 0.10 ENST00000554635.1
ENST00000557008.1
BCL2L2
BCL2L2-PABPN1
BCL2-like 2
BCL2L2-PABPN1 readthrough
chr8_+_145726472 0.10 ENST00000528430.1
PPP1R16A
protein phosphatase 1, regulatory subunit 16A
chr3_-_195270162 0.10 ENST00000438848.1
ENST00000328432.3
PPP1R2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr16_+_19535235 0.10 ENST00000565376.2
ENST00000396208.2
CCP110
centriolar coiled coil protein 110kDa
chr5_+_9546376 0.10 ENST00000509788.1
SNHG18
small nucleolar RNA host gene 18 (non-protein coding)
chr16_+_85646763 0.10 ENST00000411612.1
ENST00000253458.7
GSE1
Gse1 coiled-coil protein
chr9_-_26892342 0.10 ENST00000535437.1
CAAP1
caspase activity and apoptosis inhibitor 1
chr1_-_207095324 0.10 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr12_-_54778244 0.10 ENST00000549937.1
ZNF385A
zinc finger protein 385A
chr7_-_127032114 0.09 ENST00000436992.1
ZNF800
zinc finger protein 800
chr17_+_73717551 0.09 ENST00000450894.3
ITGB4
integrin, beta 4
chr3_+_88199099 0.09 ENST00000486971.1
C3orf38
chromosome 3 open reading frame 38
chr4_+_83956237 0.09 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr16_-_88752889 0.09 ENST00000332281.5
SNAI3
snail family zinc finger 3

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.1 0.8 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.4 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.5 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.4 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.3 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 1.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.4 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.4 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.6 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.4 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.1 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0060481 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.3 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.3 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.2 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.1 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.5 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.4 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.3 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 1.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.6 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.2 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.1 0.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 1.0 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism