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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HNF4A

Z-value: 0.82

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Transcription factors associated with HNF4A

Gene Symbol Gene ID Gene Info
HNF4A
ENSG00000101076.12 hepatocyte nuclear factor 4 alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF4Ahg19_v2_chr20_+_43029911_43029941-0.207.0e-01Click!

Activity profile of HNF4A motif

Sorted Z-values of HNF4A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_42811986 0.67 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr2_-_222436988 0.59 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4
EPH receptor A4
chr5_-_42812143 0.56 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr1_-_177939348 0.45 ENST00000464631.2
SEC16B
SEC16 homolog B (S. cerevisiae)
chr19_+_45116921 0.41 ENST00000402988.1
IGSF23
immunoglobulin superfamily, member 23
chr4_+_113152978 0.41 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr1_+_23695680 0.40 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
C1orf213
chromosome 1 open reading frame 213
chr1_-_43751230 0.39 ENST00000523677.1
C1orf210
chromosome 1 open reading frame 210
chr14_-_76447494 0.38 ENST00000238682.3
TGFB3
transforming growth factor, beta 3
chr2_-_222437049 0.35 ENST00000541600.1
EPHA4
EPH receptor A4
chr3_-_158390282 0.33 ENST00000264265.3
LXN
latexin
chr17_+_73606766 0.33 ENST00000578462.1
MYO15B
myosin XVB pseudogene
chr2_+_97454321 0.32 ENST00000540067.1
CNNM4
cyclin M4
chr11_-_73720276 0.32 ENST00000348534.4
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr17_+_4692230 0.31 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr11_+_1856034 0.30 ENST00000341958.3
SYT8
synaptotagmin VIII
chr12_-_95010147 0.29 ENST00000548918.1
TMCC3
transmembrane and coiled-coil domain family 3
chr2_-_74648702 0.27 ENST00000518863.1
C2orf81
chromosome 2 open reading frame 81
chr6_+_31950150 0.27 ENST00000537134.1
C4A
complement component 4A (Rodgers blood group)
chr2_+_14772810 0.24 ENST00000295092.2
ENST00000331243.4
FAM84A
family with sequence similarity 84, member A
chr1_+_78511586 0.24 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr1_+_94883991 0.24 ENST00000370214.4
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr11_+_27076764 0.23 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_6508100 0.23 ENST00000461727.1
ESPN
espin
chr1_+_100435315 0.22 ENST00000370155.3
ENST00000465289.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr2_-_74645669 0.21 ENST00000518401.1
C2orf81
chromosome 2 open reading frame 81
chr11_+_1855645 0.21 ENST00000381968.3
ENST00000381978.3
SYT8
synaptotagmin VIII
chr15_-_100273544 0.21 ENST00000409796.1
ENST00000545021.1
ENST00000344791.2
ENST00000332728.4
ENST00000450512.1
LYSMD4
LysM, putative peptidoglycan-binding, domain containing 4
chr12_+_121163538 0.21 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr1_-_161207875 0.20 ENST00000512372.1
ENST00000437437.2
ENST00000442691.2
ENST00000412844.2
ENST00000428574.2
ENST00000505005.1
ENST00000508740.1
ENST00000508387.1
ENST00000504010.1
ENST00000511676.1
ENST00000502985.1
ENST00000367981.3
ENST00000515621.1
ENST00000511944.1
ENST00000511748.1
ENST00000367984.4
ENST00000367985.3
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr1_+_94883931 0.20 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr10_-_116444371 0.20 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr17_+_1646130 0.20 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr1_+_100435535 0.19 ENST00000427993.2
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr1_-_161208013 0.18 ENST00000515452.1
ENST00000367983.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr12_+_56114151 0.18 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr6_-_30080876 0.18 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr6_+_30882108 0.18 ENST00000541562.1
ENST00000421263.1
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr12_-_7125770 0.17 ENST00000261407.4
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr10_-_96829246 0.17 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr3_+_37284824 0.17 ENST00000431105.1
GOLGA4
golgin A4
chr22_+_27068704 0.17 ENST00000444388.1
ENST00000450963.1
ENST00000449017.1
CTA-211A9.5
CTA-211A9.5
chr8_+_70404996 0.16 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr5_-_79950371 0.16 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
DHFR
dihydrofolate reductase
chr19_-_49339080 0.16 ENST00000595764.1
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr20_+_36661910 0.16 ENST00000373433.4
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr20_-_36156264 0.16 ENST00000445723.1
ENST00000414080.1
BLCAP
bladder cancer associated protein
chr12_-_118810688 0.16 ENST00000542532.1
ENST00000392533.3
TAOK3
TAO kinase 3
chr4_-_10023095 0.15 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr3_+_37284668 0.15 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
GOLGA4
golgin A4
chr1_-_211848899 0.15 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NEK2
NIMA-related kinase 2
chr1_-_23694794 0.15 ENST00000374608.3
ZNF436
zinc finger protein 436
chr14_+_101295948 0.15 ENST00000452514.2
MEG3
maternally expressed 3 (non-protein coding)
chr12_-_53594227 0.15 ENST00000550743.2
ITGB7
integrin, beta 7
chr18_-_61034743 0.15 ENST00000406396.3
KDSR
3-ketodihydrosphingosine reductase
chr16_-_3350614 0.15 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr13_+_50656307 0.15 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr17_-_28618867 0.15 ENST00000394819.3
ENST00000577623.1
BLMH
bleomycin hydrolase
chr12_+_56114189 0.14 ENST00000548082.1
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr12_+_121163602 0.14 ENST00000411593.2
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr2_+_159313452 0.14 ENST00000389757.3
ENST00000389759.3
PKP4
plakophilin 4
chr3_-_194072019 0.13 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chr2_+_191792376 0.13 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr1_-_177939041 0.13 ENST00000308284.6
SEC16B
SEC16 homolog B (S. cerevisiae)
chr4_+_159593271 0.13 ENST00000512251.1
ENST00000511912.1
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr9_-_27005686 0.13 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr2_-_219433014 0.13 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37
ubiquitin specific peptidase 37
chr19_-_42758040 0.12 ENST00000593944.1
ERF
Ets2 repressor factor
chr4_-_120243545 0.12 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr5_+_14664762 0.12 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr15_-_41120896 0.12 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr18_-_54318353 0.12 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr11_-_63536113 0.12 ENST00000433688.1
ENST00000546282.2
C11orf95
RP11-466C23.4
chromosome 11 open reading frame 95
RP11-466C23.4
chr17_-_36105009 0.12 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1B
HNF1 homeobox B
chr12_+_67663056 0.12 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr3_-_125775629 0.12 ENST00000383598.2
SLC41A3
solute carrier family 41, member 3
chr6_+_80341000 0.12 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr1_-_161207986 0.12 ENST00000506209.1
ENST00000367980.2
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr3_+_63898275 0.12 ENST00000538065.1
ATXN7
ataxin 7
chr12_-_95009837 0.11 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr5_+_133842243 0.11 ENST00000515627.2
AC005355.2
AC005355.2
chr17_-_7082861 0.11 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr14_-_76447336 0.11 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr16_+_21244986 0.11 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr2_+_219433588 0.11 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr4_+_113152881 0.11 ENST00000274000.5
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr19_+_10197463 0.10 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr5_-_16509101 0.10 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr6_-_30080863 0.10 ENST00000540829.1
TRIM31
tripartite motif containing 31
chrX_-_77041685 0.10 ENST00000373344.5
ENST00000395603.3
ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr2_-_180871780 0.10 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr10_-_21186144 0.10 ENST00000377119.1
NEBL
nebulette
chr20_+_62694461 0.10 ENST00000343484.5
ENST00000395053.3
TCEA2
transcription elongation factor A (SII), 2
chr3_+_63897605 0.09 ENST00000487717.1
ATXN7
ataxin 7
chr9_-_136605042 0.09 ENST00000371872.4
ENST00000298628.5
ENST00000422262.2
SARDH
sarcosine dehydrogenase
chr3_-_125313934 0.09 ENST00000296220.5
OSBPL11
oxysterol binding protein-like 11
chr19_+_4639514 0.09 ENST00000327473.4
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr1_-_161207953 0.09 ENST00000367982.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr6_+_30881982 0.09 ENST00000321897.5
ENST00000416670.2
ENST00000542001.1
ENST00000428017.1
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr19_+_7660716 0.09 ENST00000160298.4
ENST00000446248.2
CAMSAP3
calmodulin regulated spectrin-associated protein family, member 3
chr8_+_96037255 0.09 ENST00000286687.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr16_+_66600294 0.09 ENST00000535705.1
ENST00000332695.7
ENST00000336328.6
ENST00000528324.1
ENST00000531885.1
ENST00000529506.1
ENST00000457188.2
ENST00000533666.1
ENST00000533953.1
ENST00000379500.2
ENST00000328020.6
CMTM1
CKLF-like MARVEL transmembrane domain containing 1
chr14_-_23446003 0.09 ENST00000553911.1
AJUBA
ajuba LIM protein
chr16_-_88752889 0.08 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr10_+_102106829 0.08 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr12_-_54121261 0.08 ENST00000549784.1
ENST00000262059.4
CALCOCO1
calcium binding and coiled-coil domain 1
chr15_+_81489213 0.08 ENST00000559383.1
ENST00000394660.2
IL16
interleukin 16
chr4_+_144312659 0.08 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr2_-_43019698 0.08 ENST00000431905.1
ENST00000294973.6
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
chr2_+_48796120 0.08 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr17_-_38256973 0.07 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr17_-_27503770 0.07 ENST00000533112.1
MYO18A
myosin XVIIIA
chr20_+_44486246 0.07 ENST00000255152.2
ENST00000454862.2
ZSWIM3
zinc finger, SWIM-type containing 3
chr10_+_96698406 0.07 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr9_-_15307200 0.07 ENST00000506891.1
ENST00000541445.1
ENST00000512701.2
ENST00000380850.4
ENST00000297615.5
ENST00000355694.2
TTC39B
tetratricopeptide repeat domain 39B
chr15_+_101142722 0.07 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
ASB7
ankyrin repeat and SOCS box containing 7
chr15_+_50716576 0.07 ENST00000560297.1
ENST00000307179.4
ENST00000396444.3
ENST00000433963.1
ENST00000425032.3
USP8
ubiquitin specific peptidase 8
chr3_-_141868293 0.07 ENST00000317104.7
ENST00000494358.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr12_-_54121212 0.07 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
CALCOCO1
calcium binding and coiled-coil domain 1
chrX_+_65382433 0.06 ENST00000374727.3
HEPH
hephaestin
chr6_+_31691121 0.06 ENST00000480039.1
ENST00000375810.4
ENST00000375805.2
ENST00000375809.3
ENST00000375804.2
ENST00000375814.3
ENST00000375806.2
C6orf25
chromosome 6 open reading frame 25
chr7_+_100663353 0.06 ENST00000306151.4
MUC17
mucin 17, cell surface associated
chrX_+_65382381 0.06 ENST00000519389.1
HEPH
hephaestin
chr11_-_64660916 0.06 ENST00000413053.1
MIR194-2
microRNA 194-2
chr18_+_34124507 0.06 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr17_+_41857793 0.06 ENST00000449302.3
C17orf105
chromosome 17 open reading frame 105
chr6_+_31949801 0.06 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr2_-_39348137 0.06 ENST00000426016.1
SOS1
son of sevenless homolog 1 (Drosophila)
chr4_-_120225600 0.06 ENST00000399075.4
C4orf3
chromosome 4 open reading frame 3
chr19_+_39881951 0.06 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr1_-_11863171 0.06 ENST00000376592.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr2_-_21266816 0.05 ENST00000399256.4
APOB
apolipoprotein B
chr14_+_23790655 0.05 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr17_-_7082668 0.05 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chr22_+_27068766 0.05 ENST00000435162.1
ENST00000437071.1
ENST00000440816.1
ENST00000421253.1
CTA-211A9.5
CTA-211A9.5
chr1_+_180601139 0.05 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr1_-_15911510 0.05 ENST00000375826.3
AGMAT
agmatine ureohydrolase (agmatinase)
chr6_+_31982539 0.05 ENST00000435363.2
ENST00000425700.2
C4B
complement component 4B (Chido blood group)
chr1_+_113217309 0.05 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr15_-_101142362 0.05 ENST00000559577.1
ENST00000561308.1
ENST00000560133.1
ENST00000560941.1
ENST00000559736.1
ENST00000560272.1
LINS
lines homolog (Drosophila)
chr15_+_63340775 0.05 ENST00000559281.1
ENST00000317516.7
TPM1
tropomyosin 1 (alpha)
chr15_+_63340858 0.05 ENST00000560615.1
TPM1
tropomyosin 1 (alpha)
chr12_-_121973974 0.05 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
KDM2B
lysine (K)-specific demethylase 2B
chr5_+_136070614 0.05 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr19_+_1205740 0.05 ENST00000326873.7
STK11
serine/threonine kinase 11
chr8_-_98290087 0.05 ENST00000322128.3
TSPYL5
TSPY-like 5
chr14_+_23352374 0.05 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr12_-_6665200 0.05 ENST00000336604.4
ENST00000396840.2
ENST00000356896.4
IFFO1
intermediate filament family orphan 1
chr11_-_64163297 0.05 ENST00000457725.1
AP003774.6
AP003774.6
chr10_+_81065975 0.04 ENST00000446377.2
ZMIZ1
zinc finger, MIZ-type containing 1
chr19_-_12886327 0.04 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2
hook microtubule-tethering protein 2
chr13_+_52586517 0.04 ENST00000523764.1
ENST00000521508.1
ALG11
ALG11, alpha-1,2-mannosyltransferase
chr17_+_4853442 0.04 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr12_-_46384334 0.04 ENST00000369367.3
ENST00000266589.6
ENST00000395453.2
ENST00000395454.2
SCAF11
SR-related CTD-associated factor 11
chr12_+_121416489 0.04 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr16_+_19429018 0.04 ENST00000542583.2
TMC5
transmembrane channel-like 5
chr19_+_10196981 0.04 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr11_-_71750865 0.04 ENST00000544129.1
NUMA1
nuclear mitotic apparatus protein 1
chr7_+_33765593 0.04 ENST00000311067.3
RP11-89N17.1
HCG1643653; Uncharacterized protein
chr14_+_39735411 0.04 ENST00000603904.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr12_+_53497263 0.04 ENST00000551896.1
ENST00000301466.3
SOAT2
sterol O-acyltransferase 2
chr14_+_23790690 0.04 ENST00000556821.1
PABPN1
poly(A) binding protein, nuclear 1
chr6_+_43028182 0.04 ENST00000394058.1
KLC4
kinesin light chain 4
chr14_+_77647966 0.04 ENST00000554766.1
TMEM63C
transmembrane protein 63C
chr3_-_120400960 0.04 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr5_-_32444828 0.03 ENST00000265069.8
ZFR
zinc finger RNA binding protein
chr15_+_63340734 0.03 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr11_+_119056178 0.03 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZD3
PDZ domain containing 3
chr10_-_103815874 0.03 ENST00000370033.4
ENST00000311122.5
C10orf76
chromosome 10 open reading frame 76
chr19_-_35625765 0.03 ENST00000591633.1
LGI4
leucine-rich repeat LGI family, member 4
chr1_-_43751276 0.03 ENST00000423420.1
C1orf210
chromosome 1 open reading frame 210
chr8_+_104831554 0.03 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr10_+_70320413 0.03 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chr11_-_71781096 0.03 ENST00000535087.1
ENST00000535838.1
NUMA1
nuclear mitotic apparatus protein 1
chr1_+_113217073 0.03 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_-_41131326 0.03 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr12_+_121416437 0.03 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1A
HNF1 homeobox A
chr6_+_32146131 0.03 ENST00000375094.3
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr2_+_219135115 0.02 ENST00000248451.3
ENST00000273077.4
PNKD
paroxysmal nonkinesigenic dyskinesia
chr17_-_2614927 0.02 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr1_+_241695670 0.02 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr19_-_48867171 0.02 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr7_+_143080063 0.02 ENST00000446634.1
ZYX
zyxin
chr19_+_46806856 0.02 ENST00000300862.3
HIF3A
hypoxia inducible factor 3, alpha subunit
chr1_-_29508321 0.02 ENST00000546138.1
SRSF4
serine/arginine-rich splicing factor 4
chr9_-_35685452 0.02 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr17_-_44896047 0.02 ENST00000225512.5
WNT3
wingless-type MMTV integration site family, member 3
chr22_+_19950060 0.02 ENST00000449653.1
COMT
catechol-O-methyltransferase
chr6_-_33385823 0.02 ENST00000494751.1
ENST00000374496.3
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr20_-_36156293 0.02 ENST00000373537.2
ENST00000414542.2
BLCAP
bladder cancer associated protein
chr2_-_21266935 0.01 ENST00000233242.1
APOB
apolipoprotein B
chr1_+_241695424 0.01 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr12_-_39837192 0.01 ENST00000361961.3
ENST00000395670.3
KIF21A
kinesin family member 21A
chr3_+_9745510 0.01 ENST00000383831.3
CPNE9
copine family member IX
chr6_+_147527103 0.01 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr3_+_123813509 0.01 ENST00000460856.1
ENST00000240874.3
KALRN
kalirin, RhoGEF kinase
chr1_+_113217345 0.01 ENST00000357443.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_-_26197744 0.01 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr4_+_109541740 0.01 ENST00000394665.1
RPL34
ribosomal protein L34
chr1_-_151138323 0.01 ENST00000368908.5
LYSMD1
LysM, putative peptidoglycan-binding, domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF4A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 0.5 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.2 0.5 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.4 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.2 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.2 GO:0035565 regulation of pronephros size(GO:0035565)
0.0 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.6 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.0 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.5 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:1901162 primary amino compound biosynthetic process(GO:1901162)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.6 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.4 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.0 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS