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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXA6

Z-value: 0.30

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Transcription factors associated with HOXA6

Gene Symbol Gene ID Gene Info
ENSG00000106006.6 homeobox A6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA6hg19_v2_chr7_-_27187393_271873930.246.5e-01Click!

Activity profile of HOXA6 motif

Sorted Z-values of HOXA6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_57197224 0.16 ENST00000554597.1
ENST00000556696.1
Uncharacterized protein
chr2_+_47454054 0.14 ENST00000426892.1
AC106869.2
chr10_-_106240032 0.11 ENST00000447860.1
RP11-127O4.3
chr3_-_54962100 0.11 ENST00000273286.5
leucine-rich repeats and transmembrane domains 1
chr17_-_46682321 0.11 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr4_-_184243561 0.11 ENST00000514470.1
ENST00000541814.1
claudin 24
chr12_-_86650077 0.10 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_+_144980954 0.09 ENST00000367525.3
utrophin
chr16_+_24621546 0.09 ENST00000566108.1
CTD-2540M10.1
chr10_+_118083919 0.09 ENST00000333254.3
coiled-coil domain containing 172
chrX_+_28605516 0.08 ENST00000378993.1
interleukin 1 receptor accessory protein-like 1
chr17_-_46688334 0.08 ENST00000239165.7
homeobox B7
chr7_-_27205136 0.08 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr7_+_129015671 0.07 ENST00000466993.1
adenosylhomocysteinase-like 2
chr2_+_182850743 0.07 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr17_-_39123144 0.07 ENST00000355612.2
keratin 39
chr4_-_40516560 0.07 ENST00000513473.1
RNA binding motif protein 47
chr11_-_8285405 0.07 ENST00000335790.3
ENST00000534484.1
LIM domain only 1 (rhombotin 1)
chr17_-_77924627 0.07 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1 domain family, member 16
chr2_+_33359473 0.06 ENST00000432635.1
latent transforming growth factor beta binding protein 1
chr7_+_129015484 0.06 ENST00000490911.1
adenosylhomocysteinase-like 2
chr12_-_91576561 0.06 ENST00000547568.2
ENST00000552962.1
decorin
chr17_-_26220366 0.06 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYR motif containing 9
Uncharacterized protein
chr7_-_33842742 0.06 ENST00000420185.1
ENST00000440034.1
RP11-89N17.4
chr3_+_41236325 0.06 ENST00000426215.1
ENST00000405570.1
catenin (cadherin-associated protein), beta 1, 88kDa
chr2_+_226265364 0.06 ENST00000272907.6
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr7_-_27142290 0.06 ENST00000222718.5
homeobox A2
chr12_-_117799446 0.06 ENST00000317775.6
ENST00000344089.3
nitric oxide synthase 1 (neuronal)
chr4_+_129731074 0.06 ENST00000512960.1
ENST00000503785.1
ENST00000514740.1
jade family PHD finger 1
chr6_+_45296048 0.06 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
runt-related transcription factor 2
chr11_+_131240593 0.06 ENST00000539799.1
neurotrimin
chr12_-_91576750 0.06 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
decorin
chr17_-_38859996 0.05 ENST00000264651.2
keratin 24
chr2_+_182850551 0.05 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr17_+_39846114 0.05 ENST00000586699.1
eukaryotic translation initiation factor 1
chr14_-_92413353 0.05 ENST00000556154.1
fibulin 5
chr4_+_41258786 0.05 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr6_+_130339710 0.05 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr16_+_2732476 0.05 ENST00000301738.4
ENST00000564195.1
potassium channel tetramerization domain containing 5
chr3_-_71353892 0.05 ENST00000484350.1
forkhead box P1
chr13_-_30683005 0.05 ENST00000413591.1
ENST00000432770.1
long intergenic non-protein coding RNA 365
chr21_-_35899113 0.05 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr17_-_46657473 0.05 ENST00000332503.5
homeobox B4
chr3_-_69402828 0.05 ENST00000460709.1
FERM domain containing 4B
chr11_-_8290263 0.05 ENST00000428101.2
LIM domain only 1 (rhombotin 1)
chr14_-_92413727 0.05 ENST00000267620.10
fibulin 5
chr2_+_66918558 0.05 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
chrX_+_135279179 0.05 ENST00000370676.3
four and a half LIM domains 1
chr11_+_123396528 0.05 ENST00000322282.7
ENST00000529750.1
GRAM domain containing 1B
chr18_-_52989525 0.05 ENST00000457482.3
transcription factor 4
chr15_+_36994210 0.05 ENST00000562489.1
chromosome 15 open reading frame 41
chr7_-_83824449 0.05 ENST00000420047.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_+_123396307 0.05 ENST00000456860.2
GRAM domain containing 1B
chr8_+_70476088 0.05 ENST00000525999.1
sulfatase 1
chr6_-_85474219 0.05 ENST00000369663.5
T-box 18
chr20_-_50418972 0.05 ENST00000395997.3
spalt-like transcription factor 4
chr12_-_16761007 0.05 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr7_-_14026063 0.05 ENST00000443608.1
ENST00000438956.1
ets variant 1
chr4_+_160188889 0.04 ENST00000264431.4
Rap guanine nucleotide exchange factor (GEF) 2
chr8_-_72268721 0.04 ENST00000419131.1
ENST00000388743.2
eyes absent homolog 1 (Drosophila)
chr7_-_112726393 0.04 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
G protein-coupled receptor 85
chr1_+_65730385 0.04 ENST00000263441.7
ENST00000395325.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr8_+_142264664 0.04 ENST00000518520.1
Uncharacterized protein
chr11_-_117695449 0.04 ENST00000292079.2
FXYD domain containing ion transport regulator 2
chr8_-_18744528 0.04 ENST00000523619.1
pleckstrin and Sec7 domain containing 3
chr5_+_59783941 0.04 ENST00000506884.1
ENST00000504876.2
prostate androgen-regulated transcript 1 (non-protein coding)
chr7_+_114055052 0.04 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
forkhead box P2
chr1_-_98515395 0.04 ENST00000424528.2
MIR137 host gene (non-protein coding)
chr6_+_149721495 0.04 ENST00000326669.4
small ubiquitin-like modifier 4
chr20_+_62795827 0.04 ENST00000328439.1
ENST00000536311.1
myelin transcription factor 1
chr8_-_25281747 0.04 ENST00000421054.2
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr14_-_98444386 0.04 ENST00000556462.1
ENST00000556138.1
chromosome 14 open reading frame 64
chr12_-_12674032 0.04 ENST00000298573.4
dual specificity phosphatase 16
chr6_+_15401075 0.03 ENST00000541660.1
jumonji, AT rich interactive domain 2
chrX_-_19688475 0.03 ENST00000541422.1
SH3-domain kinase binding protein 1
chr17_-_46671323 0.03 ENST00000239151.5
homeobox B5
chr2_-_164592497 0.03 ENST00000333129.3
ENST00000409634.1
fidgetin
chr17_-_47045949 0.03 ENST00000357424.2
gastric inhibitory polypeptide
chr16_-_51185172 0.03 ENST00000251020.4
spalt-like transcription factor 1
chr9_+_2015335 0.03 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_-_94673956 0.03 ENST00000551941.1
Uncharacterized protein
chr22_-_36236265 0.03 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr14_+_61654271 0.03 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
protein kinase C, eta
chr18_-_52989217 0.03 ENST00000570287.2
transcription factor 4
chr7_-_41742697 0.03 ENST00000242208.4
inhibin, beta A
chr16_+_89334512 0.03 ENST00000602042.1
AC137932.1
chrX_-_15683147 0.03 ENST00000380342.3
transmembrane protein 27
chr3_-_114477787 0.03 ENST00000464560.1
zinc finger and BTB domain containing 20
chr12_-_16761117 0.03 ENST00000538051.1
LIM domain only 3 (rhombotin-like 2)
chr2_+_33359687 0.03 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr6_+_136172820 0.03 ENST00000308191.6
phosphodiesterase 7B
chr12_-_92536433 0.03 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
chromosome 12 open reading frame 79
chr17_+_74536115 0.03 ENST00000592014.1
progressive rod-cone degeneration
chrX_+_135251783 0.03 ENST00000394153.2
four and a half LIM domains 1
chr9_-_124989804 0.03 ENST00000373755.2
ENST00000373754.2
LIM homeobox 6
chr4_-_41884620 0.03 ENST00000504870.1
long intergenic non-protein coding RNA 682
chr11_+_22696314 0.03 ENST00000532398.1
ENST00000433790.1
growth arrest-specific 2
chr1_+_41174988 0.03 ENST00000372652.1
nuclear transcription factor Y, gamma
chr2_+_54785485 0.03 ENST00000333896.5
spectrin, beta, non-erythrocytic 1
chr7_-_83824169 0.03 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr7_+_28452130 0.03 ENST00000357727.2
cAMP responsive element binding protein 5
chr6_+_45296391 0.02 ENST00000371436.6
ENST00000576263.1
runt-related transcription factor 2
chr8_-_72268889 0.02 ENST00000388742.4
eyes absent homolog 1 (Drosophila)
chr2_+_33359646 0.02 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr18_+_20714525 0.02 ENST00000400473.2
Cdk5 and Abl enzyme substrate 1
chr7_-_14026123 0.02 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ets variant 1
chrX_+_135251835 0.02 ENST00000456445.1
four and a half LIM domains 1
chr12_-_16759440 0.02 ENST00000537304.1
LIM domain only 3 (rhombotin-like 2)
chr5_-_88119580 0.02 ENST00000539796.1
myocyte enhancer factor 2C
chr17_-_39623681 0.02 ENST00000225899.3
keratin 32
chrX_-_124097620 0.02 ENST00000371130.3
ENST00000422452.2
teneurin transmembrane protein 1
chr3_-_65583561 0.02 ENST00000460329.2
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr3_-_71294304 0.02 ENST00000498215.1
forkhead box P1
chr14_-_98444369 0.02 ENST00000554822.1
chromosome 14 open reading frame 64
chr13_+_36050881 0.02 ENST00000537702.1
neurobeachin
chr14_-_69261310 0.02 ENST00000336440.3
ZFP36 ring finger protein-like 1
chr8_-_122653630 0.02 ENST00000303924.4
hyaluronan synthase 2
chr2_+_162272605 0.02 ENST00000389554.3
T-box, brain, 1
chr2_+_173955327 0.02 ENST00000422149.1
Mitogen-activated protein kinase kinase kinase MLT
chr1_+_206557366 0.02 ENST00000414007.1
ENST00000419187.2
SLIT-ROBO Rho GTPase activating protein 2
chr1_+_186265399 0.02 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
proteoglycan 4
chrX_+_135252050 0.02 ENST00000449474.1
ENST00000345434.3
four and a half LIM domains 1
chr8_+_104831554 0.02 ENST00000408894.2
regulating synaptic membrane exocytosis 2
chr15_-_54025300 0.02 ENST00000559418.1
WD repeat domain 72
chr10_+_24528108 0.02 ENST00000438429.1
KIAA1217
chr4_+_96012585 0.02 ENST00000502683.1
bone morphogenetic protein receptor, type IB
chr12_-_53994805 0.02 ENST00000328463.7
activating transcription factor 7
chr2_+_17997763 0.02 ENST00000281047.3
mesogenin 1
chr17_+_42634844 0.02 ENST00000315323.3
frizzled family receptor 2
chrX_-_33357558 0.02 ENST00000288447.4
dystrophin
chr3_-_27764190 0.02 ENST00000537516.1
eomesodermin
chrX_-_33146477 0.02 ENST00000378677.2
dystrophin
chr12_-_99548645 0.02 ENST00000549025.2
ankyrin repeat and sterile alpha motif domain containing 1B
chr13_-_95131923 0.02 ENST00000377028.5
ENST00000446125.1
dopachrome tautomerase
chr3_-_114477962 0.02 ENST00000471418.1
zinc finger and BTB domain containing 20
chr11_+_131240373 0.02 ENST00000374791.3
ENST00000436745.1
neurotrimin
chr7_-_104909435 0.02 ENST00000357311.3
SRSF protein kinase 2
chr14_+_72052983 0.01 ENST00000358550.2
signal-induced proliferation-associated 1 like 1
chr7_-_111424462 0.01 ENST00000437129.1
dedicator of cytokinesis 4
chr1_+_12538594 0.01 ENST00000543710.1
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr17_-_38911580 0.01 ENST00000312150.4
keratin 25
chr5_-_88179302 0.01 ENST00000504921.2
myocyte enhancer factor 2C
chr8_+_55528627 0.01 ENST00000220676.1
retinitis pigmentosa 1 (autosomal dominant)
chr7_+_39017504 0.01 ENST00000403058.1
POU class 6 homeobox 2
chr15_+_93443419 0.01 ENST00000557381.1
ENST00000420239.2
chromodomain helicase DNA binding protein 2
chr20_+_11898507 0.01 ENST00000378226.2
BTB (POZ) domain containing 3
chr21_-_39870339 0.01 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
v-ets avian erythroblastosis virus E26 oncogene homolog
chr18_-_22932080 0.01 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
zinc finger protein 521
chr14_-_98444438 0.01 ENST00000512901.2
chromosome 14 open reading frame 64
chr11_-_84634217 0.01 ENST00000524982.1
discs, large homolog 2 (Drosophila)
chr13_-_103719196 0.01 ENST00000245312.3
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr2_-_163695128 0.01 ENST00000332142.5
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr2_-_233641265 0.01 ENST00000438786.1
ENST00000409779.1
ENST00000233826.3
potassium inwardly-rectifying channel, subfamily J, member 13
chr1_+_167298281 0.01 ENST00000367862.5
POU class 2 homeobox 1
chr20_-_50418947 0.01 ENST00000371539.3
spalt-like transcription factor 4
chr7_-_112727774 0.01 ENST00000297146.3
ENST00000501255.2
G protein-coupled receptor 85
chr22_+_39101728 0.01 ENST00000216044.5
ENST00000484657.1
GTP binding protein 1
chr11_-_36619771 0.01 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
recombination activating gene 2
chr2_-_175711133 0.01 ENST00000409597.1
ENST00000413882.1
chimerin 1
chr21_-_31538971 0.01 ENST00000286808.3
claudin 17
chr13_-_46425865 0.01 ENST00000400405.2
siah E3 ubiquitin protein ligase family member 3
chr12_-_16758835 0.01 ENST00000541295.1
LIM domain only 3 (rhombotin-like 2)
chr4_+_129730779 0.01 ENST00000226319.6
jade family PHD finger 1
chr10_-_33623310 0.01 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
neuropilin 1
chr6_-_138820624 0.01 ENST00000343505.5
NHS-like 1
chr10_+_77056134 0.01 ENST00000528121.1
ENST00000416398.1
ZNF503 antisense RNA 1
chr12_-_5352315 0.01 ENST00000536518.1
RP11-319E16.1
chr9_+_125796806 0.01 ENST00000373642.1
G protein-coupled receptor 21
chr8_+_77596014 0.01 ENST00000523885.1
zinc finger homeobox 4
chr7_+_18535321 0.01 ENST00000413380.1
ENST00000430454.1
histone deacetylase 9
chr11_+_22694123 0.01 ENST00000534801.1
growth arrest-specific 2
chr12_-_91576429 0.01 ENST00000552145.1
ENST00000546745.1
decorin
chr12_-_14133053 0.01 ENST00000609686.1
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr18_+_59000815 0.01 ENST00000262717.4
cadherin 20, type 2
chr12_-_16762802 0.01 ENST00000534946.1
LIM domain only 3 (rhombotin-like 2)
chr3_+_141106643 0.01 ENST00000514251.1
zinc finger and BTB domain containing 38
chr6_-_46293378 0.01 ENST00000330430.6
regulator of calcineurin 2
chr4_+_55095264 0.01 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr17_-_46608272 0.01 ENST00000577092.1
ENST00000239174.6
homeobox B1
chr12_-_102874416 0.01 ENST00000392904.1
ENST00000337514.6
insulin-like growth factor 1 (somatomedin C)
chr8_-_93107827 0.01 ENST00000520724.1
ENST00000518844.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_170632250 0.01 ENST00000367760.3
paired related homeobox 1
chr11_-_129062093 0.01 ENST00000310343.9
Rho GTPase activating protein 32
chr5_-_124084493 0.01 ENST00000509799.1
zinc finger protein 608
chr11_-_84634447 0.01 ENST00000532653.1
discs, large homolog 2 (Drosophila)
chr3_-_157824292 0.01 ENST00000483851.2
short stature homeobox 2
chr17_-_27333311 0.01 ENST00000317338.12
ENST00000585644.1
seizure related 6 homolog (mouse)
chr7_+_142374104 0.01 ENST00000604952.1
MT-RNR2-like 6
chr8_+_104892639 0.01 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr3_+_173302222 0.01 ENST00000361589.4
neuroligin 1
chr9_-_124990680 0.01 ENST00000541397.2
ENST00000560485.1
LIM homeobox 6
chr4_-_110223799 0.01 ENST00000399132.1
ENST00000399126.1
ENST00000505591.1
collagen, type XXV, alpha 1
chr12_-_16758873 0.01 ENST00000535535.1
LIM domain only 3 (rhombotin-like 2)
chr1_+_6105974 0.01 ENST00000378083.3
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr1_+_84630352 0.01 ENST00000450730.1
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_16758304 0.01 ENST00000320122.6
LIM domain only 3 (rhombotin-like 2)
chr2_-_161056762 0.01 ENST00000428609.2
ENST00000409967.2
integrin, beta 6
chr12_-_16758059 0.01 ENST00000261169.6
LIM domain only 3 (rhombotin-like 2)
chr13_-_103053946 0.01 ENST00000376131.4
fibroblast growth factor 14
chr6_-_154568815 0.01 ENST00000519344.1
interaction protein for cytohesin exchange factors 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.1 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:1904499 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.0 GO:0021553 olfactory nerve development(GO:0021553)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)