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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXB3

Z-value: 0.80

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Transcription factors associated with HOXB3

Gene Symbol Gene ID Gene Info
HOXB3
ENSG00000120093.7 homeobox B3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB3hg19_v2_chr17_-_46667628_466676420.503.2e-01Click!

Activity profile of HOXB3 motif

Sorted Z-values of HOXB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_191221240 0.48 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr11_-_26593779 0.44 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr9_+_135937365 0.40 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr17_+_62223320 0.39 ENST00000580828.1
ENST00000582965.1
SNORA76
small nucleolar RNA, H/ACA box 76
chr4_-_87515202 0.38 ENST00000502302.1
ENST00000513186.1
MAPK10
mitogen-activated protein kinase 10
chr1_+_62439037 0.36 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr5_+_115177178 0.36 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr3_+_121774202 0.36 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr6_+_134274354 0.35 ENST00000367869.1
TBPL1
TBP-like 1
chr3_-_143567262 0.34 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr1_-_197115818 0.32 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr22_-_29107919 0.32 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr7_-_73256838 0.31 ENST00000297873.4
WBSCR27
Williams Beuren syndrome chromosome region 27
chr16_-_3350614 0.31 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr20_+_58571419 0.30 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26
cadherin 26
chr2_+_54350316 0.30 ENST00000606865.1
ACYP2
acylphosphatase 2, muscle type
chr14_+_39944025 0.30 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr7_+_74379083 0.30 ENST00000361825.7
GATSL1
GATS protein-like 1
chr11_-_118134997 0.29 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr2_+_87769459 0.28 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr2_+_187371440 0.28 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr2_+_172778952 0.27 ENST00000392584.1
ENST00000264108.4
HAT1
histone acetyltransferase 1
chr2_+_183982255 0.27 ENST00000455063.1
NUP35
nucleoporin 35kDa
chr14_-_100046444 0.27 ENST00000554996.1
CCDC85C
coiled-coil domain containing 85C
chr3_+_195447738 0.27 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr14_-_54908043 0.26 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr2_+_138722028 0.26 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr2_-_112237835 0.26 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr16_-_66864806 0.26 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr6_+_127898312 0.26 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr6_-_82462425 0.26 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr14_+_57671888 0.26 ENST00000391612.1
AL391152.1
AL391152.1
chr5_+_136070614 0.25 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chrX_+_77166172 0.25 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr11_+_95523621 0.24 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
CEP57
centrosomal protein 57kDa
chr5_+_140019004 0.24 ENST00000394671.3
ENST00000511410.1
ENST00000537378.1
TMCO6
transmembrane and coiled-coil domains 6
chr12_+_16500037 0.24 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chr11_-_95523500 0.24 ENST00000540054.1
FAM76B
family with sequence similarity 76, member B
chrX_+_106045891 0.24 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1D8B
TBC1 domain family, member 8B (with GRAM domain)
chr9_+_124329336 0.24 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr6_+_26045603 0.23 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr15_+_41057818 0.23 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr2_+_191208656 0.22 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr12_+_28410128 0.22 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr2_+_191208601 0.22 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr7_-_99716914 0.22 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr4_+_95128748 0.22 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr16_+_53133070 0.21 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr1_+_209602156 0.21 ENST00000429156.1
ENST00000366437.3
ENST00000603283.1
ENST00000431096.1
MIR205HG
MIR205 host gene (non-protein coding)
chr4_-_176733897 0.20 ENST00000393658.2
GPM6A
glycoprotein M6A
chr12_-_50643664 0.20 ENST00000550592.1
LIMA1
LIM domain and actin binding 1
chr22_+_21996549 0.20 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr14_-_73360796 0.20 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr1_+_144989309 0.20 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr11_-_26593677 0.20 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr12_+_102514019 0.19 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARPBP
PARP1 binding protein
chr9_+_131062367 0.19 ENST00000601297.1
AL359091.2
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr11_-_95522639 0.18 ENST00000536839.1
FAM76B
family with sequence similarity 76, member B
chr6_-_82957433 0.18 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr5_+_110427983 0.18 ENST00000513710.2
ENST00000505303.1
WDR36
WD repeat domain 36
chr12_-_10022735 0.18 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr2_+_191208791 0.18 ENST00000423767.1
ENST00000451089.1
INPP1
inositol polyphosphate-1-phosphatase
chr11_+_121447469 0.17 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr1_+_158978768 0.17 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr12_+_128399965 0.17 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr15_-_44969086 0.17 ENST00000434130.1
ENST00000560780.1
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr3_+_136537816 0.17 ENST00000446465.2
SLC35G2
solute carrier family 35, member G2
chr11_-_95522907 0.17 ENST00000358780.5
ENST00000542135.1
FAM76B
family with sequence similarity 76, member B
chr11_-_60010556 0.16 ENST00000427611.2
MS4A4E
membrane-spanning 4-domains, subfamily A, member 4E
chr12_+_128399917 0.16 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr16_-_28937027 0.16 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr6_-_111804905 0.16 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr12_-_118796910 0.16 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr1_-_68698197 0.16 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr8_-_17579726 0.16 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr3_+_136537911 0.16 ENST00000393079.3
SLC35G2
solute carrier family 35, member G2
chr7_-_33102338 0.16 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr9_-_103115135 0.16 ENST00000537512.1
TEX10
testis expressed 10
chr6_+_90192974 0.15 ENST00000520458.1
ANKRD6
ankyrin repeat domain 6
chr4_+_175204818 0.15 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr6_+_149721495 0.15 ENST00000326669.4
SUMO4
small ubiquitin-like modifier 4
chr15_+_84841242 0.15 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr11_+_17281900 0.15 ENST00000530527.1
NUCB2
nucleobindin 2
chr4_+_86525299 0.14 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr19_+_17638059 0.14 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr12_-_118796971 0.14 ENST00000542902.1
TAOK3
TAO kinase 3
chr6_-_111136513 0.14 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr15_+_78830023 0.14 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr1_-_68698222 0.14 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr8_+_121457642 0.14 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr7_+_55980331 0.14 ENST00000429591.2
ZNF713
zinc finger protein 713
chr22_-_32766972 0.13 ENST00000382084.4
ENST00000382086.2
RFPL3S
RFPL3 antisense
chr16_+_31724552 0.13 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720
zinc finger protein 720
chr14_+_32798547 0.13 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr15_+_92006567 0.13 ENST00000554333.1
RP11-661P17.1
RP11-661P17.1
chr7_+_105603657 0.13 ENST00000542731.1
ENST00000343407.5
CDHR3
cadherin-related family member 3
chr2_+_201242941 0.13 ENST00000449647.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr6_+_26087509 0.13 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr12_+_122688090 0.13 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr2_-_88125471 0.13 ENST00000398146.3
RGPD2
RANBP2-like and GRIP domain containing 2
chr4_+_123161120 0.13 ENST00000446180.1
KIAA1109
KIAA1109
chr12_+_22778116 0.13 ENST00000538218.1
ETNK1
ethanolamine kinase 1
chr4_-_74486109 0.13 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_-_146040968 0.13 ENST00000401010.3
NBPF11
neuroblastoma breakpoint family, member 11
chr4_-_25865159 0.13 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr4_-_111563076 0.12 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr11_+_118398178 0.12 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr2_-_169887827 0.12 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr2_-_111334678 0.12 ENST00000329516.3
ENST00000330331.5
ENST00000446930.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr17_-_57229155 0.12 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr2_+_172309634 0.12 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr8_+_92114060 0.12 ENST00000518304.1
LRRC69
leucine rich repeat containing 69
chr21_-_15918618 0.12 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr9_+_125132803 0.12 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_+_64798095 0.12 ENST00000332707.5
XPOT
exportin, tRNA
chr9_+_125133315 0.11 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr3_-_48659193 0.11 ENST00000330862.3
TMEM89
transmembrane protein 89
chr8_-_41166953 0.11 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr22_+_24199113 0.11 ENST00000405847.1
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr3_+_158519654 0.11 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chr3_-_164875850 0.11 ENST00000472120.1
RP11-747D18.1
RP11-747D18.1
chr5_+_140019079 0.11 ENST00000252100.6
TMCO6
transmembrane and coiled-coil domains 6
chr4_+_139230865 0.11 ENST00000502757.1
ENST00000507145.1
ENST00000515282.1
ENST00000510736.1
LINC00499
long intergenic non-protein coding RNA 499
chr12_+_18414446 0.11 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr14_+_32798462 0.11 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr2_+_29336855 0.11 ENST00000404424.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr5_-_32444828 0.10 ENST00000265069.8
ZFR
zinc finger RNA binding protein
chr1_+_202317815 0.10 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr12_-_15815626 0.10 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr19_+_9296279 0.10 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr1_+_160370344 0.10 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr4_-_40632844 0.10 ENST00000505414.1
RBM47
RNA binding motif protein 47
chr15_-_55562451 0.10 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr3_+_147657764 0.10 ENST00000467198.1
ENST00000485006.1
RP11-71N10.1
RP11-71N10.1
chr11_-_119991589 0.10 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr8_-_49834299 0.10 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr4_-_146261573 0.10 ENST00000610239.1
RP11-142A22.4
RP11-142A22.4
chr14_+_85994943 0.10 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr9_-_3489406 0.10 ENST00000457373.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr12_+_22778009 0.10 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chr11_-_26593649 0.09 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr1_-_152779104 0.09 ENST00000606576.1
ENST00000368768.1
LCE1C
late cornified envelope 1C
chr1_+_16090914 0.09 ENST00000441801.2
FBLIM1
filamin binding LIM protein 1
chr3_-_151034734 0.09 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr11_-_96076334 0.09 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr17_-_33390667 0.09 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr7_-_33102399 0.09 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr6_+_150690028 0.09 ENST00000229447.5
ENST00000344419.3
IYD
iodotyrosine deiodinase
chr12_-_6484376 0.09 ENST00000360168.3
ENST00000358945.3
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr17_+_30348024 0.09 ENST00000327564.7
ENST00000584368.1
ENST00000394713.3
ENST00000341671.7
LRRC37B
leucine rich repeat containing 37B
chr16_+_28763108 0.09 ENST00000357796.3
ENST00000550983.1
NPIPB9
nuclear pore complex interacting protein family, member B9
chr11_-_104905840 0.09 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr4_+_25162253 0.09 ENST00000512921.1
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr8_-_121457608 0.09 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr14_-_90085458 0.09 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr7_-_99717463 0.09 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr3_-_121740969 0.09 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr7_+_26331541 0.09 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr4_+_119199864 0.08 ENST00000602414.1
ENST00000602520.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr16_-_31085514 0.08 ENST00000300849.4
ZNF668
zinc finger protein 668
chr1_+_174843548 0.08 ENST00000478442.1
ENST00000465412.1
RABGAP1L
RAB GTPase activating protein 1-like
chr22_-_50219548 0.08 ENST00000404034.1
BRD1
bromodomain containing 1
chr10_+_5090940 0.08 ENST00000602997.1
AKR1C3
aldo-keto reductase family 1, member C3
chr7_-_99277610 0.08 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
chr1_+_159750776 0.08 ENST00000368107.1
DUSP23
dual specificity phosphatase 23
chr13_-_47471155 0.08 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr3_-_44519131 0.08 ENST00000425708.2
ENST00000396077.2
ZNF445
zinc finger protein 445
chr6_+_55192267 0.08 ENST00000340465.2
GFRAL
GDNF family receptor alpha like
chr8_+_92261516 0.08 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr12_-_22063787 0.08 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr14_-_70883708 0.08 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr4_-_175204765 0.07 ENST00000513696.1
ENST00000503293.1
FBXO8
F-box protein 8
chr4_+_110736659 0.07 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chrX_-_48824793 0.07 ENST00000376477.1
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr2_+_86669118 0.07 ENST00000427678.1
ENST00000542128.1
KDM3A
lysine (K)-specific demethylase 3A
chr4_+_37455536 0.07 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr5_-_140027357 0.07 ENST00000252102.4
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr9_+_125133467 0.07 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_13134045 0.07 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr8_-_30670384 0.07 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr17_-_8113542 0.07 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
AURKB
aurora kinase B
chr1_-_159832438 0.07 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr4_+_144312659 0.07 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chrX_+_72783026 0.07 ENST00000373504.6
ENST00000373502.5
CHIC1
cysteine-rich hydrophobic domain 1
chr19_-_3557570 0.07 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr20_-_40247002 0.07 ENST00000373222.3
CHD6
chromodomain helicase DNA binding protein 6
chr16_+_14280564 0.07 ENST00000572567.1
MKL2
MKL/myocardin-like 2
chr6_-_160209471 0.07 ENST00000539948.1
TCP1
t-complex 1
chr1_+_207226574 0.07 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr3_-_176914191 0.07 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr1_+_202317855 0.07 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr19_+_1261106 0.06 ENST00000588411.1
CIRBP
cold inducible RNA binding protein
chr7_+_100860949 0.06 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr3_+_28390637 0.06 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr19_+_17638041 0.06 ENST00000601861.1
FAM129C
family with sequence similarity 129, member C
chr3_+_153599269 0.06 ENST00000463297.1
RP11-217E22.5
RP11-217E22.5
chr5_+_36608422 0.06 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_63439013 0.06 ENST00000398868.3
ATL3
atlastin GTPase 3
chr6_+_47666275 0.06 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr19_+_48949087 0.06 ENST00000598711.1
GRWD1
glutamate-rich WD repeat containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:0034756 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.2 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.2 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.3 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.1 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.0 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.0 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.0 0.1 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0051808 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290) formaldehyde metabolic process(GO:0046292)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.4 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.0 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.3 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors