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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXB7

Z-value: 0.74

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Transcription factors associated with HOXB7

Gene Symbol Gene ID Gene Info
ENSG00000260027.3 homeobox B7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB7hg19_v2_chr17_-_46688334_466883850.335.2e-01Click!

Activity profile of HOXB7 motif

Sorted Z-values of HOXB7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_131409476 0.64 ENST00000296871.2
colony stimulating factor 2 (granulocyte-macrophage)
chr10_-_106240032 0.48 ENST00000447860.1
RP11-127O4.3
chr7_-_33842742 0.37 ENST00000420185.1
ENST00000440034.1
RP11-89N17.4
chr12_-_86650077 0.34 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_+_21679220 0.33 ENST00000256969.2
chromosome 12 open reading frame 39
chr11_-_57194817 0.32 ENST00000529748.1
ENST00000525474.1
solute carrier family 43, member 3
chr19_+_12203100 0.32 ENST00000596883.1
zinc finger family member 788
chr11_+_18154059 0.31 ENST00000531264.1
MAS-related GPR, member X3
chr4_+_71384257 0.31 ENST00000339336.4
amelotin
chr4_+_71384300 0.30 ENST00000504451.1
amelotin
chr19_+_35417939 0.29 ENST00000601142.1
ENST00000426813.2
zinc finger protein 30
chr9_+_74729511 0.28 ENST00000545168.1
guanine deaminase
chr10_+_69865866 0.28 ENST00000354393.2
myopalladin
chr17_+_70036164 0.28 ENST00000602013.1
Uncharacterized protein
chr6_+_130339710 0.28 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr4_-_85771168 0.26 ENST00000514071.1
WD repeat and FYVE domain containing 3
chr4_+_26324474 0.26 ENST00000514675.1
recombination signal binding protein for immunoglobulin kappa J region
chr22_-_30642728 0.25 ENST00000403987.3
leukemia inhibitory factor
chr12_-_91546926 0.25 ENST00000550758.1
decorin
chr22_-_30642782 0.24 ENST00000249075.3
leukemia inhibitory factor
chr16_+_77756399 0.24 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr19_+_12203069 0.23 ENST00000430298.2
ENST00000339302.4
zinc finger family member 788
Zinc finger protein 788
chr8_-_91618285 0.23 ENST00000517505.1
long intergenic non-protein coding RNA 1030
chr3_+_177545563 0.23 ENST00000434309.1
RP11-91K9.1
chr10_-_51958906 0.21 ENST00000489640.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr19_+_35417844 0.21 ENST00000601957.1
zinc finger protein 30
chr4_-_186570679 0.21 ENST00000451974.1
sorbin and SH3 domain containing 2
chr19_+_48774586 0.20 ENST00000594024.1
ENST00000595408.1
ENST00000315849.1
zinc finger protein 114
chr4_+_158493642 0.20 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
chr1_-_92952433 0.20 ENST00000294702.5
growth factor independent 1 transcription repressor
chr15_-_28957469 0.20 ENST00000563027.1
ENST00000340249.3
golgin A8 family, member M
chr11_-_2162162 0.19 ENST00000381389.1
insulin-like growth factor 2 (somatomedin A)
chr11_+_44117219 0.19 ENST00000532479.1
ENST00000527014.1
exostosin glycosyltransferase 2
chr2_-_208030295 0.19 ENST00000458272.1
Kruppel-like factor 7 (ubiquitous)
chrX_+_1387693 0.18 ENST00000381529.3
ENST00000432318.2
ENST00000361536.3
ENST00000501036.2
ENST00000381524.3
ENST00000412290.1
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr12_-_7596735 0.18 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163 molecule-like 1
chr15_+_64680003 0.18 ENST00000261884.3
thyroid hormone receptor interactor 4
chr18_+_61554932 0.17 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr17_-_69198295 0.17 ENST00000569074.1
cancer susceptibility candidate 17 (non-protein coding)
chr16_-_66583994 0.17 ENST00000564917.1
thymidine kinase 2, mitochondrial
chr3_-_141747950 0.17 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_224624730 0.17 ENST00000445239.1
WD repeat domain 26
chr19_+_35417798 0.17 ENST00000303586.7
ENST00000439785.1
ENST00000601540.1
zinc finger protein 30
chr1_-_206288647 0.16 ENST00000331555.5
chromosome 1 open reading frame 186
chr12_-_95510743 0.16 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chr16_-_66583701 0.16 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
thymidine kinase 2, mitochondrial
chr19_+_37837218 0.16 ENST00000591134.1
HKR1, GLI-Kruppel zinc finger family member
chr2_+_166095898 0.16 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr3_+_173116225 0.16 ENST00000457714.1
neuroligin 1
chr5_+_140227357 0.16 ENST00000378122.3
protocadherin alpha 9
chr2_-_70780770 0.16 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
transforming growth factor, alpha
chr21_-_31588365 0.15 ENST00000399899.1
claudin 8
chr20_+_25388293 0.15 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr14_-_34931458 0.15 ENST00000298130.4
serine palmitoyltransferase, small subunit A
chr18_+_22040593 0.15 ENST00000256906.4
histamine receptor H4
chr12_+_96252706 0.15 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr16_-_30122717 0.15 ENST00000566613.1
glycerophosphodiester phosphodiesterase domain containing 3
chr11_+_44117099 0.15 ENST00000533608.1
exostosin glycosyltransferase 2
chr11_+_44117260 0.15 ENST00000358681.4
exostosin glycosyltransferase 2
chr17_-_4938712 0.15 ENST00000254853.5
ENST00000424747.1
solute carrier family 52 (riboflavin transporter), member 1
chr18_+_20714525 0.14 ENST00000400473.2
Cdk5 and Abl enzyme substrate 1
chr13_-_113242439 0.14 ENST00000375669.3
ENST00000261965.3
tubulin, gamma complex associated protein 3
chr22_-_22337154 0.14 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
topoisomerase (DNA) III beta
chr2_-_203735484 0.14 ENST00000420558.1
ENST00000418208.1
islet cell autoantigen 1,69kDa-like
chr2_+_120436760 0.14 ENST00000445518.1
ENST00000409951.1
transmembrane protein 177
chr10_+_90484301 0.13 ENST00000404190.1
lipase, family member K
chr16_-_66584059 0.13 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
thymidine kinase 2, mitochondrial
chr6_+_89674246 0.13 ENST00000369474.1
Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr4_+_36283213 0.13 ENST00000357504.3
death domain containing 1
chr7_-_120498357 0.13 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr16_-_65106110 0.13 ENST00000562882.1
ENST00000567934.1
cadherin 11, type 2, OB-cadherin (osteoblast)
chr14_+_55034599 0.13 ENST00000392067.3
ENST00000357634.3
sterile alpha motif domain containing 4A
chr13_-_103719196 0.13 ENST00000245312.3
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr7_+_117824086 0.13 ENST00000249299.2
ENST00000424702.1
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr12_+_52056548 0.13 ENST00000545061.1
ENST00000355133.3
sodium channel, voltage gated, type VIII, alpha subunit
chr1_-_91487806 0.13 ENST00000361321.5
zinc finger protein 644
chr12_-_118628315 0.13 ENST00000540561.1
TAO kinase 3
chr15_-_32695396 0.13 ENST00000512626.2
ENST00000435655.2
golgin A8 family, member K
Uncharacterized protein; cDNA FLJ52611
chr15_-_23692381 0.13 ENST00000567107.1
ENST00000345070.5
ENST00000312015.5
golgin A6 family-like 2
chr16_+_15596123 0.13 ENST00000452191.2
chromosome 16 open reading frame 45
chr12_+_123944070 0.13 ENST00000412157.2
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr8_-_37411648 0.13 ENST00000519738.1
RP11-150O12.1
chr8_+_31497271 0.12 ENST00000520407.1
neuregulin 1
chr9_-_70465758 0.12 ENST00000489273.1
COBW domain containing 5
chr11_-_8795787 0.12 ENST00000528196.1
ENST00000533681.1
suppression of tumorigenicity 5
chr20_-_1309809 0.12 ENST00000360779.3
syndecan binding protein (syntenin) 2
chr20_-_50179368 0.12 ENST00000609943.1
ENST00000609507.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr18_-_73967160 0.12 ENST00000579714.1
RP11-94B19.7
chr3_+_101659682 0.12 ENST00000465215.1
RP11-221J22.1
chr16_-_67427389 0.12 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr15_-_60683326 0.12 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
annexin A2
chr2_+_27886330 0.11 ENST00000326019.6
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr12_-_39734783 0.11 ENST00000552961.1
kinesin family member 21A
chr7_-_7782204 0.11 ENST00000418534.2
AC007161.5
chr3_+_157827841 0.11 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
arginine/serine-rich coiled-coil 1
chr11_+_57365150 0.11 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr8_-_29208183 0.11 ENST00000240100.2
dual specificity phosphatase 4
chr10_+_102891048 0.11 ENST00000467928.2
T-cell leukemia homeobox 1
chr16_-_66584015 0.11 ENST00000545043.2
thymidine kinase 2, mitochondrial
chr21_-_33984456 0.11 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
Uncharacterized protein
chromosome 21 open reading frame 59
chr19_+_52693259 0.11 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
protein phosphatase 2, regulatory subunit A, alpha
chr3_+_136581096 0.11 ENST00000476286.1
ENST00000488930.1
NCK adaptor protein 1
chr11_-_102668879 0.11 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr3_+_158787041 0.11 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chr15_+_86098670 0.11 ENST00000558811.1
A kinase (PRKA) anchor protein 13
chr2_+_234600253 0.11 ENST00000373424.1
ENST00000441351.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr17_+_22022437 0.11 ENST00000540040.1
MT-RNR2-like 1
chr3_+_159557637 0.11 ENST00000445224.2
schwannomin interacting protein 1
chr15_+_75575176 0.11 ENST00000434739.3
golgin A6 family, member D
chr13_-_46756351 0.10 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_101295407 0.10 ENST00000596284.1
AL117190.2
chr8_-_109799793 0.10 ENST00000297459.3
transmembrane protein 74
chr12_+_8309630 0.10 ENST00000396570.3
zinc finger protein 705A
chr12_+_59989791 0.10 ENST00000552432.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr14_+_74417192 0.10 ENST00000554320.1
coenzyme Q6 monooxygenase
chr1_-_165414414 0.10 ENST00000359842.5
retinoid X receptor, gamma
chr9_+_140135665 0.10 ENST00000340384.4
tubulin, beta 4B class IVb
chr3_+_140947563 0.10 ENST00000505013.1
acid phosphatase-like 2
chr15_+_28623784 0.10 ENST00000526619.2
ENST00000337838.7
ENST00000532622.2
golgin A8 family, member F
chr3_+_139063372 0.10 ENST00000478464.1
mitochondrial ribosomal protein S22
chr12_-_47226152 0.10 ENST00000546940.1
solute carrier family 38, member 4
chr10_+_118083919 0.10 ENST00000333254.3
coiled-coil domain containing 172
chr1_+_152956549 0.10 ENST00000307122.2
small proline-rich protein 1A
chr7_-_86595190 0.10 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324-like
chr15_-_28778117 0.10 ENST00000525590.2
ENST00000329523.6
golgin A8 family, member G
chr8_-_116681123 0.10 ENST00000519674.1
trichorhinophalangeal syndrome I
chr10_+_69869237 0.10 ENST00000373675.3
myopalladin
chr5_-_10761206 0.10 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr1_-_209957882 0.10 ENST00000294811.1
chromosome 1 open reading frame 74
chr17_+_45973516 0.10 ENST00000376741.4
Sp2 transcription factor
chr19_-_48753064 0.10 ENST00000520153.1
ENST00000357778.5
ENST00000520015.1
caspase recruitment domain family, member 8
chr3_+_52570610 0.10 ENST00000307106.3
ENST00000477703.1
ENST00000476842.1
small integral membrane protein 4
chr9_-_85882145 0.10 ENST00000328788.1
FERM domain containing 3
chr14_+_103851712 0.09 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MAP/microtubule affinity-regulating kinase 3
chr12_-_28124903 0.09 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
parathyroid hormone-like hormone
chr12_-_11139511 0.09 ENST00000506868.1
taste receptor, type 2, member 50
chr3_-_4927447 0.09 ENST00000449914.1
Uncharacterized protein
chr3_-_24207039 0.09 ENST00000280696.5
thyroid hormone receptor, beta
chr2_+_44396000 0.09 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr1_+_66820058 0.09 ENST00000480109.2
phosphodiesterase 4B, cAMP-specific
chr3_+_156009623 0.09 ENST00000389634.5
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr6_-_116866773 0.09 ENST00000368602.3
trafficking protein particle complex 3-like
chr17_+_7477040 0.09 ENST00000581384.1
ENST00000577929.1
eukaryotic translation initiation factor 4A1
chr8_-_10512569 0.09 ENST00000382483.3
retinitis pigmentosa 1-like 1
chr19_-_20748614 0.09 ENST00000596797.1
zinc finger protein 737
chr8_-_116681686 0.09 ENST00000519815.1
trichorhinophalangeal syndrome I
chr11_+_71927807 0.09 ENST00000298223.6
ENST00000454954.2
ENST00000541003.1
ENST00000539412.1
ENST00000536778.1
ENST00000535625.1
ENST00000321324.7
folate receptor 2 (fetal)
chr7_-_138363824 0.09 ENST00000419765.3
SVOP-like
chr16_+_20911174 0.09 ENST00000568663.1
LYR motif containing 1
chr9_+_131267052 0.09 ENST00000539582.1
GLE1 RNA export mediator
chr7_-_105926058 0.09 ENST00000417537.1
nicotinamide phosphoribosyltransferase
chr15_+_30375158 0.09 ENST00000341650.6
ENST00000567927.1
golgin A8 family, member J
chr4_+_71600144 0.09 ENST00000502653.1
RUN and FYVE domain containing 3
chr15_+_67418047 0.09 ENST00000540846.2
SMAD family member 3
chr2_-_230787879 0.09 ENST00000435716.1
thyroid hormone receptor interactor 12
chr17_+_41363854 0.08 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
transmembrane protein 106A
chr6_-_15548591 0.08 ENST00000509674.1
dystrobrevin binding protein 1
chr9_+_77112244 0.08 ENST00000376896.3
RAR-related orphan receptor B
chr2_+_44001172 0.08 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
dynein, cytoplasmic 2, light intermediate chain 1
chr1_-_20503917 0.08 ENST00000429261.2
phospholipase A2, group IIC
chr3_-_139396787 0.08 ENST00000296202.7
ENST00000509291.1
nicotinamide nucleotide adenylyltransferase 3
chr16_+_82660635 0.08 ENST00000567445.1
ENST00000446376.2
cadherin 13
chrX_-_110655391 0.08 ENST00000356915.2
ENST00000356220.3
doublecortin
chr11_-_107729287 0.08 ENST00000375682.4
solute carrier family 35, member F2
chr4_-_69434245 0.08 ENST00000317746.2
UDP glucuronosyltransferase 2 family, polypeptide B17
chr5_+_125759140 0.08 ENST00000543198.1
GRAM domain containing 3
chr1_+_244515930 0.08 ENST00000366537.1
ENST00000308105.4
chromosome 1 open reading frame 100
chr8_-_67874805 0.08 ENST00000563496.1
transcription factor 24
chr10_+_124320156 0.08 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr14_+_24584056 0.08 ENST00000561001.1
DDB1 and CUL4 associated factor 11
chr8_+_68864330 0.08 ENST00000288368.4
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr7_+_116654935 0.08 ENST00000432298.1
ENST00000422922.1
suppression of tumorigenicity 7
chr19_+_44645700 0.08 ENST00000592437.1
zinc finger protein 234
chr16_+_67880574 0.08 ENST00000219169.4
nuclear transport factor 2
chr17_-_38821373 0.08 ENST00000394052.3
keratin 222
chr14_+_24584372 0.08 ENST00000559396.1
ENST00000558638.1
ENST00000561041.1
ENST00000559288.1
ENST00000558408.1
DDB1 and CUL4 associated factor 11
chr1_-_9953295 0.08 ENST00000377258.1
catenin, beta interacting protein 1
chr1_-_40562908 0.08 ENST00000527311.2
ENST00000449045.2
ENST00000372779.4
palmitoyl-protein thioesterase 1
chr15_-_32747835 0.08 ENST00000509311.2
ENST00000414865.2
golgin A8 family, member O
chr15_+_43477455 0.08 ENST00000300213.4
cyclin D-type binding-protein 1
chrX_+_1734051 0.08 ENST00000381229.4
ENST00000381233.3
acetylserotonin O-methyltransferase
chr19_-_49955050 0.08 ENST00000262265.5
PIH1 domain containing 1
chr4_-_186734275 0.08 ENST00000456060.1
sorbin and SH3 domain containing 2
chr12_+_56401268 0.08 ENST00000262032.5
IKAROS family zinc finger 4 (Eos)
chr6_-_74231444 0.08 ENST00000331523.2
ENST00000356303.2
eukaryotic translation elongation factor 1 alpha 1
chrM_+_9207 0.07 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr2_-_74735707 0.07 ENST00000233630.6
polycomb group ring finger 1
chr6_-_90025011 0.07 ENST00000402938.3
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr4_-_177116772 0.07 ENST00000280191.2
spermatogenesis associated 4
chr7_-_107883678 0.07 ENST00000417701.1
neuronal cell adhesion molecule
chr19_+_41698927 0.07 ENST00000310054.4
cytochrome P450, family 2, subfamily S, polypeptide 1
chr2_-_43266680 0.07 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
chr19_+_38880252 0.07 ENST00000586301.1
sprouty-related, EVH1 domain containing 3
chrX_-_110655306 0.07 ENST00000371993.2
doublecortin
chr10_-_128975273 0.07 ENST00000424811.2
family with sequence similarity 196, member A
chr12_-_109025849 0.07 ENST00000228463.6
selectin P ligand
chr14_+_35747825 0.07 ENST00000540871.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr12_+_54402790 0.07 ENST00000040584.4
homeobox C8
chr12_+_9980069 0.07 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
killer cell lectin-like receptor subfamily F, member 1
chr12_-_54653313 0.07 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.6 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.6 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) positive regulation of tooth mineralization(GO:0070172)
0.1 0.2 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.2 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.3 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0052416 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0071231 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) cellular response to folic acid(GO:0071231)
0.0 0.1 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:2000619 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0048858 cell projection morphogenesis(GO:0048858)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0072025 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.0 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0046549 amacrine cell differentiation(GO:0035881) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.0 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.3 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.0 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.6 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.5 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.3 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis