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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXD1

Z-value: 0.31

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Transcription factors associated with HOXD1

Gene Symbol Gene ID Gene Info
ENSG00000128645.11 homeobox D1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD1hg19_v2_chr2_+_177053307_1770534020.443.8e-01Click!

Activity profile of HOXD1 motif

Sorted Z-values of HOXD1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_57229155 0.29 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr9_-_5339873 0.21 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr7_+_37723450 0.10 ENST00000447769.1
G protein-coupled receptor 141
chr10_-_4285835 0.10 ENST00000454470.1
long intergenic non-protein coding RNA 702
chr5_+_36606700 0.10 ENST00000416645.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_+_135596180 0.09 ENST00000283054.4
ENST00000392928.1
aminocarboxymuconate semialdehyde decarboxylase
chr7_+_37723336 0.09 ENST00000450180.1
G protein-coupled receptor 141
chr5_+_66300446 0.09 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr10_-_99205607 0.08 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
exosome component 1
chr7_-_99716940 0.07 ENST00000440225.1
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chrX_+_107288280 0.07 ENST00000458383.1
V-set and immunoglobulin domain containing 1
chr2_+_135596106 0.07 ENST00000356140.5
aminocarboxymuconate semialdehyde decarboxylase
chr10_-_72142345 0.07 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
leucine rich repeat containing 20
chr1_+_117544366 0.06 ENST00000256652.4
ENST00000369470.1
CD101 molecule
chr11_-_102651343 0.06 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr7_-_99716952 0.05 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr11_+_101918153 0.05 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
chromosome 11 open reading frame 70
chr19_+_11071546 0.05 ENST00000358026.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr10_-_4285923 0.05 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr3_-_99569821 0.05 ENST00000487087.1
filamin A interacting protein 1-like
chr20_-_50418972 0.05 ENST00000395997.3
spalt-like transcription factor 4
chr5_+_66300464 0.05 ENST00000436277.1
microtubule associated serine/threonine kinase family member 4
chr5_+_176811431 0.04 ENST00000512593.1
ENST00000324417.5
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr10_+_18549645 0.04 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr2_+_11682790 0.04 ENST00000389825.3
ENST00000381483.2
growth regulation by estrogen in breast cancer 1
chr4_+_113568207 0.04 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr4_+_71019903 0.04 ENST00000344526.5
chromosome 4 open reading frame 40
chr7_+_37723420 0.04 ENST00000476620.1
ependymin related 1
chr19_+_50016610 0.04 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr12_+_28410128 0.03 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chr15_-_37393406 0.03 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr22_+_24951949 0.03 ENST00000402849.1
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr7_-_55620433 0.02 ENST00000418904.1
vesicular, overexpressed in cancer, prosurvival protein 1
chr20_-_50418947 0.02 ENST00000371539.3
spalt-like transcription factor 4
chrX_+_43515467 0.02 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr7_+_99717230 0.02 ENST00000262932.3
canopy FGF signaling regulator 4
chr17_-_27418537 0.02 ENST00000408971.2
TGFB1-induced anti-apoptotic factor 1
chr2_+_228736335 0.02 ENST00000440997.1
ENST00000545118.1
dynein assembly factor with WDR repeat domains 1
chr4_+_105828537 0.02 ENST00000515649.1
RP11-556I14.1
chr3_+_111718173 0.02 ENST00000494932.1
transgelin 3
chr14_+_32798462 0.02 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr15_+_63050785 0.02 ENST00000472902.1
talin 2
chr17_+_18086392 0.02 ENST00000541285.1
alkB, alkylation repair homolog 5 (E. coli)
chr3_+_2933893 0.02 ENST00000397459.2
contactin 4
chr4_-_150736962 0.02 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
chr10_+_99205894 0.02 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr7_-_99717463 0.02 ENST00000437822.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr4_-_119759795 0.02 ENST00000419654.2
SEC24 family member D
chr11_+_65554493 0.02 ENST00000335987.3
ovo-like zinc finger 1
chr14_+_74034310 0.02 ENST00000538782.1
acyl-CoA thioesterase 2
chr11_+_47293795 0.02 ENST00000422579.1
MAP-kinase activating death domain
chr13_+_36050881 0.02 ENST00000537702.1
neurobeachin
chr2_-_99871570 0.01 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
lysozyme G-like 2
chr14_+_57671888 0.01 ENST00000391612.1
AL391152.1
chr5_-_96478466 0.01 ENST00000274382.4
Lix1 homolog (chicken)
chr20_+_43990576 0.01 ENST00000372727.1
ENST00000414310.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr16_+_53133070 0.01 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr11_+_71900572 0.01 ENST00000312293.4
folate receptor 1 (adult)
chr5_+_148737562 0.01 ENST00000274569.4
prenylcysteine oxidase 1 like
chr8_+_92261516 0.01 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr11_-_71823266 0.01 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
anaphase promoting complex subunit 15
chr3_-_101039402 0.01 ENST00000193391.7
interphotoreceptor matrix proteoglycan 2
chrX_-_19504642 0.01 ENST00000469203.2
mitogen-activated protein kinase kinase kinase 15
chr2_+_191221240 0.01 ENST00000409027.1
ENST00000458193.1
inositol polyphosphate-1-phosphatase
chrX_+_107288239 0.01 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr13_+_78315348 0.01 ENST00000441784.1
SLAIN motif family, member 1
chr12_-_52761262 0.01 ENST00000257901.3
keratin 85
chr6_+_130742231 0.01 ENST00000545622.1
transmembrane protein 200A
chr13_+_78315295 0.01 ENST00000351546.3
SLAIN motif family, member 1
chr12_+_15699286 0.01 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
protein tyrosine phosphatase, receptor type, O
chr14_+_56584414 0.01 ENST00000559044.1
pellino E3 ubiquitin protein ligase family member 2
chr11_+_71900703 0.01 ENST00000393681.2
folate receptor 1 (adult)
chr5_-_20575959 0.01 ENST00000507958.1
cadherin 18, type 2
chr10_+_99205959 0.00 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr4_-_138453606 0.00 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr19_-_36001113 0.00 ENST00000434389.1
dermokine
chr4_+_86748898 0.00 ENST00000509300.1
Rho GTPase activating protein 24
chr19_-_3557570 0.00 ENST00000355415.2
major facilitator superfamily domain containing 12
chr4_+_144312659 0.00 ENST00000509992.1
GRB2-associated binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)