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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HSF4

Z-value: 0.65

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Transcription factors associated with HSF4

Gene Symbol Gene ID Gene Info
HSF4
ENSG00000102878.11 heat shock transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF4hg19_v2_chr16_+_67198683_67198715-0.562.5e-01Click!

Activity profile of HSF4 motif

Sorted Z-values of HSF4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_44497455 0.40 ENST00000592005.1
KATNAL2
katanin p60 subunit A-like 2
chr7_-_56119156 0.38 ENST00000421312.1
ENST00000416592.1
PSPH
phosphoserine phosphatase
chr13_-_31736132 0.31 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr13_-_31736027 0.31 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chr5_+_133707252 0.29 ENST00000506787.1
ENST00000507277.1
UBE2B
ubiquitin-conjugating enzyme E2B
chr11_-_914774 0.24 ENST00000528154.1
ENST00000525840.1
CHID1
chitinase domain containing 1
chr13_-_31736478 0.24 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr7_+_157129738 0.23 ENST00000437030.1
DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr1_+_156308245 0.23 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC
TSSK6 activating co-chaperone
chr11_-_82997371 0.23 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr1_-_245026388 0.20 ENST00000440865.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr9_-_6015607 0.20 ENST00000259569.5
RANBP6
RAN binding protein 6
chr11_-_89956461 0.20 ENST00000320585.6
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr11_+_63953691 0.19 ENST00000543847.1
STIP1
stress-induced-phosphoprotein 1
chr18_+_9136758 0.19 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr10_-_90611566 0.18 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr18_-_6929829 0.18 ENST00000583840.1
ENST00000581571.1
ENST00000578497.1
ENST00000579012.1
LINC00668
long intergenic non-protein coding RNA 668
chr9_+_109685630 0.18 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr14_-_52535712 0.18 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr21_+_35445811 0.17 ENST00000399312.2
MRPS6
mitochondrial ribosomal protein S6
chr19_+_1354930 0.17 ENST00000591337.1
MUM1
melanoma associated antigen (mutated) 1
chr11_-_111781554 0.17 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr12_-_110883346 0.17 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr7_+_56119323 0.16 ENST00000275603.4
ENST00000335503.3
ENST00000540286.1
CCT6A
chaperonin containing TCP1, subunit 6A (zeta 1)
chr13_-_31191642 0.16 ENST00000405805.1
HMGB1
high mobility group box 1
chr11_-_89956227 0.16 ENST00000457199.2
ENST00000530765.1
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr15_-_44092295 0.15 ENST00000249714.3
ENST00000299969.6
ENST00000319327.6
SERINC4
serine incorporator 4
chr16_-_1494490 0.15 ENST00000389176.3
ENST00000409671.1
CCDC154
coiled-coil domain containing 154
chr22_+_29168652 0.15 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr4_-_40632881 0.15 ENST00000511598.1
RBM47
RNA binding motif protein 47
chr19_-_49565254 0.15 ENST00000593537.1
NTF4
neurotrophin 4
chr3_-_53080644 0.14 ENST00000497586.1
SFMBT1
Scm-like with four mbt domains 1
chr2_+_210444298 0.14 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr11_-_122933043 0.13 ENST00000534624.1
ENST00000453788.2
ENST00000527387.1
HSPA8
heat shock 70kDa protein 8
chr20_-_60573188 0.13 ENST00000474089.1
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr6_+_35704804 0.13 ENST00000373869.3
ARMC12
armadillo repeat containing 12
chr6_-_138833630 0.13 ENST00000533765.1
NHSL1
NHS-like 1
chr11_+_107799118 0.13 ENST00000320578.2
RAB39A
RAB39A, member RAS oncogene family
chr14_-_102553371 0.13 ENST00000553585.1
ENST00000216281.8
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr11_+_28724129 0.13 ENST00000513853.1
RP11-115J23.1
RP11-115J23.1
chr20_+_57430162 0.12 ENST00000450130.1
ENST00000349036.3
ENST00000423897.1
GNAS
GNAS complex locus
chr2_-_69664586 0.12 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chrX_-_106243451 0.12 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr2_-_198364581 0.12 ENST00000428204.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr2_-_198364552 0.12 ENST00000439605.1
ENST00000418022.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr17_+_44701402 0.12 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr11_-_122932730 0.12 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8
heat shock 70kDa protein 8
chr10_-_74856608 0.11 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr14_+_63671105 0.11 ENST00000316754.3
RHOJ
ras homolog family member J
chr5_+_118690466 0.11 ENST00000503646.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chrX_+_123094672 0.11 ENST00000354548.5
ENST00000458700.1
STAG2
stromal antigen 2
chr8_-_81083618 0.11 ENST00000520795.1
TPD52
tumor protein D52
chr12_+_2904102 0.10 ENST00000001008.4
FKBP4
FK506 binding protein 4, 59kDa
chr8_+_143781883 0.10 ENST00000522591.1
LY6K
lymphocyte antigen 6 complex, locus K
chrX_-_102943022 0.10 ENST00000433176.2
MORF4L2
mortality factor 4 like 2
chr15_+_96869165 0.10 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr3_+_130613226 0.10 ENST00000509662.1
ENST00000328560.8
ENST00000428331.2
ENST00000359644.3
ENST00000422190.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chrX_+_108779870 0.10 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr22_-_41252962 0.10 ENST00000216218.3
ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr11_-_14913765 0.10 ENST00000334636.5
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr2_-_97405775 0.10 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chr9_+_74764278 0.10 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr2_+_210443993 0.10 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr15_+_79165151 0.10 ENST00000331268.5
MORF4L1
mortality factor 4 like 1
chrX_-_106243294 0.10 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr21_+_45148735 0.10 ENST00000327574.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr1_-_45987526 0.09 ENST00000372079.1
ENST00000262746.1
ENST00000447184.1
ENST00000319248.8
PRDX1
peroxiredoxin 1
chr2_+_198365095 0.09 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chrX_-_20236970 0.09 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr18_+_11751466 0.09 ENST00000535121.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr13_+_31191920 0.09 ENST00000255304.4
USPL1
ubiquitin specific peptidase like 1
chr1_+_154947126 0.09 ENST00000368439.1
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr1_+_212782012 0.09 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr21_+_45937497 0.09 ENST00000354333.5
C21orf90
chromosome 21 open reading frame 90
chr9_-_88715044 0.09 ENST00000388711.3
ENST00000466178.1
GOLM1
golgi membrane protein 1
chr21_-_40720974 0.09 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1
chr12_-_110939870 0.09 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr11_-_62457371 0.09 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr11_-_134123142 0.09 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1
chr1_-_149459549 0.09 ENST00000369175.3
FAM72C
family with sequence similarity 72, member C
chr20_+_58203664 0.08 ENST00000541461.1
PHACTR3
phosphatase and actin regulator 3
chr6_+_44215603 0.08 ENST00000371554.1
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr5_+_172571445 0.08 ENST00000231668.9
ENST00000351486.5
ENST00000352523.6
ENST00000393770.4
BNIP1
BCL2/adenovirus E1B 19kDa interacting protein 1
chr20_-_23807358 0.08 ENST00000304725.2
CST2
cystatin SA
chr11_+_20385327 0.08 ENST00000451739.2
ENST00000532505.1
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr1_-_26232522 0.08 ENST00000399728.1
STMN1
stathmin 1
chr18_+_11751493 0.08 ENST00000269162.5
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr7_+_157129660 0.08 ENST00000429029.2
ENST00000262177.4
ENST00000417758.1
ENST00000452797.2
ENST00000443280.1
DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr19_-_49567124 0.08 ENST00000301411.3
NTF4
neurotrophin 4
chr19_+_859654 0.08 ENST00000592860.1
CFD
complement factor D (adipsin)
chr1_+_156308403 0.08 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chr6_-_106773291 0.07 ENST00000343245.3
ATG5
autophagy related 5
chr2_+_85766280 0.07 ENST00000306434.3
MAT2A
methionine adenosyltransferase II, alpha
chr19_+_6135646 0.07 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr3_-_183735651 0.07 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chrX_+_150866779 0.07 ENST00000370353.3
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr9_+_33025209 0.07 ENST00000330899.4
ENST00000544625.1
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr2_+_201171577 0.07 ENST00000409397.2
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr18_+_57567180 0.07 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chrX_+_123095155 0.07 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chr12_+_41136144 0.07 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr1_-_6260896 0.07 ENST00000497965.1
RPL22
ribosomal protein L22
chr21_+_44394742 0.07 ENST00000432907.2
PKNOX1
PBX/knotted 1 homeobox 1
chrX_-_102942961 0.07 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
MORF4L2
mortality factor 4 like 2
chr3_-_53080672 0.07 ENST00000483069.1
SFMBT1
Scm-like with four mbt domains 1
chr2_-_238499303 0.07 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr3_+_186501336 0.07 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
EIF4A2
eukaryotic translation initiation factor 4A2
chr21_-_40720995 0.07 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr11_+_20385666 0.07 ENST00000532081.1
ENST00000531058.1
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr6_+_42531798 0.07 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr5_+_421030 0.07 ENST00000506456.1
AHRR
aryl-hydrocarbon receptor repressor
chr7_-_100493744 0.07 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr9_-_86593238 0.07 ENST00000351839.3
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chrX_-_80377162 0.06 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr11_+_65769946 0.06 ENST00000533166.1
BANF1
barrier to autointegration factor 1
chr1_+_92683467 0.06 ENST00000370375.3
ENST00000370373.2
C1orf146
chromosome 1 open reading frame 146
chr21_+_35445827 0.06 ENST00000608209.1
ENST00000381151.3
SLC5A3
SLC5A3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr11_+_112046190 0.06 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
BCO2
beta-carotene oxygenase 2
chr15_+_79165112 0.06 ENST00000426013.2
MORF4L1
mortality factor 4 like 1
chr8_+_143781513 0.06 ENST00000292430.6
ENST00000561179.1
ENST00000518841.1
ENST00000519387.1
LY6K
lymphocyte antigen 6 complex, locus K
chr12_+_70132632 0.06 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3IP
RAB3A interacting protein
chr22_+_32871224 0.06 ENST00000452138.1
ENST00000382058.3
ENST00000397426.1
FBXO7
F-box protein 7
chr9_-_88714421 0.06 ENST00000388712.3
GOLM1
golgi membrane protein 1
chr21_+_44394620 0.06 ENST00000291547.5
PKNOX1
PBX/knotted 1 homeobox 1
chr1_+_154947148 0.06 ENST00000368436.1
ENST00000308987.5
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr8_-_50466973 0.06 ENST00000520800.1
RP11-738G5.2
Uncharacterized protein
chr11_+_20385231 0.06 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr7_-_26240357 0.06 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr9_-_13279406 0.06 ENST00000546205.1
MPDZ
multiple PDZ domain protein
chr15_+_89921280 0.06 ENST00000560596.1
ENST00000558692.1
ENST00000538734.2
ENST00000559235.1
LINC00925
long intergenic non-protein coding RNA 925
chr18_-_19284724 0.06 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr11_-_82997013 0.06 ENST00000529073.1
ENST00000529611.1
CCDC90B
coiled-coil domain containing 90B
chr3_+_130613001 0.06 ENST00000504948.1
ENST00000513801.1
ENST00000505072.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr7_+_26240776 0.06 ENST00000337620.4
CBX3
chromobox homolog 3
chr12_-_57030096 0.06 ENST00000549506.1
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr3_+_183899770 0.06 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr4_-_159644507 0.06 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chr1_+_144811744 0.06 ENST00000338347.4
ENST00000440491.2
ENST00000375552.4
NBPF9
neuroblastoma breakpoint family, member 9
chr3_+_136676707 0.06 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr2_+_201171064 0.06 ENST00000451764.2
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr3_+_186501979 0.05 ENST00000498746.1
EIF4A2
eukaryotic translation initiation factor 4A2
chr1_+_206623784 0.05 ENST00000426388.1
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr1_+_12227035 0.05 ENST00000376259.3
ENST00000536782.1
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr12_-_4754339 0.05 ENST00000228850.1
AKAP3
A kinase (PRKA) anchor protein 3
chr2_+_201171242 0.05 ENST00000360760.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr11_+_10772847 0.05 ENST00000524523.1
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr2_+_201170770 0.05 ENST00000409988.3
ENST00000409385.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr1_-_53704157 0.05 ENST00000371466.4
ENST00000371470.3
MAGOH
mago-nashi homolog, proliferation-associated (Drosophila)
chr15_+_41952591 0.05 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA
MGA, MAX dimerization protein
chr4_+_76932326 0.05 ENST00000513353.1
ENST00000341029.5
ART3
ADP-ribosyltransferase 3
chr12_-_76817036 0.05 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr12_-_123011536 0.05 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr3_+_136676851 0.05 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr16_+_14844670 0.05 ENST00000553201.1
NPIPA2
nuclear pore complex interacting protein family, member A2
chr12_-_123011476 0.05 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2
arginine/serine-rich coiled-coil 2
chr9_+_74764340 0.05 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr17_-_62308087 0.05 ENST00000583097.1
TEX2
testis expressed 2
chr10_-_62332357 0.05 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_-_24469602 0.05 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr11_+_65769550 0.05 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
BANF1
barrier to autointegration factor 1
chr19_+_11650709 0.05 ENST00000586059.1
CNN1
calponin 1, basic, smooth muscle
chr4_+_41258786 0.05 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr15_+_79165222 0.05 ENST00000559930.1
MORF4L1
mortality factor 4 like 1
chr22_+_29664248 0.04 ENST00000406548.1
ENST00000437155.2
ENST00000415761.1
ENST00000331029.7
EWSR1
EWS RNA-binding protein 1
chr7_-_56119238 0.04 ENST00000275605.3
ENST00000395471.3
PSPH
phosphoserine phosphatase
chrX_+_123094369 0.04 ENST00000455404.1
ENST00000218089.9
STAG2
stromal antigen 2
chr2_+_201171268 0.04 ENST00000423749.1
ENST00000428692.1
ENST00000457757.1
ENST00000453663.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr17_-_40168698 0.04 ENST00000590774.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr8_-_81083731 0.04 ENST00000379096.5
TPD52
tumor protein D52
chr5_-_140053152 0.04 ENST00000542735.1
DND1
DND microRNA-mediated repression inhibitor 1
chr14_-_61124977 0.04 ENST00000554986.1
SIX1
SIX homeobox 1
chr4_-_25865159 0.04 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr14_+_72052983 0.04 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chrX_-_152989798 0.04 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31
B-cell receptor-associated protein 31
chr17_+_33474860 0.04 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr4_-_40632757 0.04 ENST00000511902.1
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr20_+_36149602 0.04 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr22_+_29664241 0.04 ENST00000436425.1
ENST00000447973.1
EWSR1
EWS RNA-binding protein 1
chr4_-_152147579 0.04 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19
SH3 domain containing 19
chrX_-_73072534 0.04 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr19_-_14628645 0.04 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_+_201171372 0.04 ENST00000409140.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr8_+_37594130 0.04 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2
ER lipid raft associated 2
chr4_-_17513702 0.04 ENST00000428702.2
ENST00000508623.1
ENST00000513615.1
QDPR
quinoid dihydropteridine reductase
chr2_+_223162866 0.04 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chrX_-_152939133 0.03 ENST00000370150.1
PNCK
pregnancy up-regulated nonubiquitous CaM kinase
chr5_+_56469775 0.03 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr1_-_205904950 0.03 ENST00000340781.4
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr12_-_48500085 0.03 ENST00000549518.1
SENP1
SUMO1/sentrin specific peptidase 1
chrX_-_154563889 0.03 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr8_+_62200509 0.03 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1
clavesin 1
chr11_-_111781454 0.03 ENST00000533280.1
CRYAB
crystallin, alpha B
chr15_-_58357866 0.03 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr1_+_44679159 0.03 ENST00000315913.5
ENST00000372289.2
DMAP1
DNA methyltransferase 1 associated protein 1
chr12_+_70132458 0.03 ENST00000247833.7
RAB3IP
RAB3A interacting protein
chr16_-_18468926 0.03 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chrX_+_54947229 0.03 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chrX_-_80377118 0.03 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr8_-_37594944 0.03 ENST00000330539.1
RP11-863K10.7
Uncharacterized protein
chrX_-_100548045 0.03 ENST00000372907.3
ENST00000372905.2
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.2 GO:0002368 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.2 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.3 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.3 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.0 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.0 0.0 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:1904851 positive regulation of establishment of protein localization to telomere(GO:1904851)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0015825 L-serine transport(GO:0015825)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 1.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0043196 varicosity(GO:0043196)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)