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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IKZF2

Z-value: 0.57

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Transcription factors associated with IKZF2

Gene Symbol Gene ID Gene Info
IKZF2
ENSG00000030419.12 IKAROS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IKZF2hg19_v2_chr2_-_214016314_2140163430.786.9e-02Click!

Activity profile of IKZF2 motif

Sorted Z-values of IKZF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_43741594 0.34 ENST00000536181.1
ENST00000378069.4
MAOB
monoamine oxidase B
chr9_+_92219919 0.34 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr5_-_42811986 0.31 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr13_+_20268547 0.30 ENST00000601204.1
AL354808.2
AL354808.2
chr8_-_72268721 0.28 ENST00000419131.1
ENST00000388743.2
EYA1
eyes absent homolog 1 (Drosophila)
chr14_+_32546145 0.28 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr5_-_42812143 0.28 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr9_+_67968793 0.25 ENST00000417488.1
RP11-195B21.3
Protein LOC644249
chr9_-_3469181 0.25 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr21_+_17791648 0.25 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_+_28605426 0.23 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr3_+_178865887 0.21 ENST00000477735.1
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr20_+_52105495 0.20 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr13_-_38172863 0.20 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chrX_-_45629661 0.20 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
RP6-99M1.2
chr10_-_98031310 0.18 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr9_-_6015607 0.18 ENST00000259569.5
RANBP6
RAN binding protein 6
chr2_+_114163945 0.18 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr4_-_153303658 0.17 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr21_+_35107346 0.17 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr14_+_32546274 0.17 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr6_-_10435032 0.17 ENST00000491317.1
ENST00000496285.1
ENST00000479822.1
ENST00000487130.1
LINC00518
long intergenic non-protein coding RNA 518
chr1_+_40627038 0.17 ENST00000372771.4
RLF
rearranged L-myc fusion
chr2_+_190722119 0.16 ENST00000452382.1
PMS1
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
chr1_-_57045228 0.16 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr14_-_23479331 0.16 ENST00000397377.1
ENST00000397379.3
ENST00000406429.2
ENST00000341470.4
ENST00000555998.1
ENST00000397376.2
ENST00000553675.1
ENST00000553931.1
ENST00000555575.1
ENST00000553958.1
ENST00000555098.1
ENST00000556419.1
ENST00000553606.1
ENST00000299088.6
ENST00000554179.1
ENST00000397382.4
C14orf93
chromosome 14 open reading frame 93
chr12_-_56367101 0.15 ENST00000549233.2
PMEL
premelanosome protein
chr10_-_116444371 0.15 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr1_-_68698197 0.15 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr2_+_197504278 0.15 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
CCDC150
coiled-coil domain containing 150
chr8_-_72268968 0.15 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr18_-_47340297 0.14 ENST00000586485.1
ENST00000587994.1
ENST00000586100.1
ENST00000285093.10
ACAA2
acetyl-CoA acyltransferase 2
chr12_-_68845417 0.14 ENST00000542875.1
RP11-81H14.2
RP11-81H14.2
chr6_-_97345689 0.14 ENST00000316149.7
NDUFAF4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr22_+_24199044 0.14 ENST00000403208.3
ENST00000398356.2
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr1_+_95616933 0.14 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr10_+_99079008 0.14 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr8_-_17942432 0.14 ENST00000381733.4
ENST00000314146.10
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr4_+_26322409 0.13 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr5_+_43602750 0.13 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr8_-_133637624 0.13 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr15_+_96876340 0.13 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_-_101767715 0.13 ENST00000376840.4
ENST00000409318.1
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chrX_-_48827976 0.13 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr1_+_100111580 0.13 ENST00000605497.1
PALMD
palmdelphin
chr2_-_174830430 0.13 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr10_-_98031265 0.12 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr17_-_6915616 0.12 ENST00000575889.1
AC027763.2
Uncharacterized protein
chr6_+_32605134 0.12 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr12_-_76461249 0.12 ENST00000551524.1
NAP1L1
nucleosome assembly protein 1-like 1
chr8_+_97597148 0.12 ENST00000521590.1
SDC2
syndecan 2
chr2_+_181988620 0.12 ENST00000428474.1
ENST00000424655.1
AC104820.2
AC104820.2
chr14_-_55493763 0.12 ENST00000455555.1
ENST00000360586.3
ENST00000421192.1
ENST00000420358.2
WDHD1
WD repeat and HMG-box DNA binding protein 1
chr4_-_153274078 0.12 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr6_+_147830063 0.12 ENST00000367474.1
SAMD5
sterile alpha motif domain containing 5
chr3_+_177159744 0.12 ENST00000439009.1
LINC00578
long intergenic non-protein coding RNA 578
chr10_+_22614547 0.12 ENST00000416820.1
BMI1
BMI1 polycomb ring finger oncogene
chr15_+_69373210 0.12 ENST00000435479.1
ENST00000559870.1
LINC00277
RP11-809H16.5
long intergenic non-protein coding RNA 277
RP11-809H16.5
chr10_-_119805558 0.12 ENST00000369199.3
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr2_-_214014959 0.12 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_-_6580094 0.11 ENST00000361716.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr10_-_79398250 0.11 ENST00000286627.5
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_-_25568687 0.11 ENST00000581944.1
RP11-663N22.1
RP11-663N22.1
chr17_+_55055466 0.11 ENST00000262288.3
ENST00000572710.1
ENST00000575395.1
SCPEP1
serine carboxypeptidase 1
chr4_-_74486109 0.11 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr7_+_79765071 0.11 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr8_-_72268889 0.11 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr21_-_16374688 0.11 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr14_-_35591156 0.11 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chrX_-_117119243 0.11 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr15_-_90358564 0.11 ENST00000559874.1
ANPEP
alanyl (membrane) aminopeptidase
chr8_-_6420759 0.11 ENST00000523120.1
ANGPT2
angiopoietin 2
chr5_+_94955782 0.10 ENST00000380007.2
GPR150
G protein-coupled receptor 150
chr11_+_125464758 0.10 ENST00000529886.1
STT3A
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr15_-_83837983 0.10 ENST00000562702.1
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr13_+_97874574 0.10 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr6_-_11779403 0.10 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chrX_+_45364633 0.10 ENST00000435394.1
ENST00000609127.1
RP11-245M24.1
RP11-245M24.1
chr1_+_212475148 0.10 ENST00000537030.3
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr8_+_9183618 0.10 ENST00000518619.1
RP11-115J16.1
RP11-115J16.1
chr1_+_117963209 0.10 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr1_-_67600639 0.10 ENST00000544837.1
ENST00000603691.1
C1orf141
chromosome 1 open reading frame 141
chr1_-_68698222 0.10 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chrX_+_80457442 0.10 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr2_-_134326009 0.10 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr18_-_53089723 0.09 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr6_+_32605195 0.09 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr1_-_234831899 0.09 ENST00000442382.1
RP4-781K5.6
RP4-781K5.6
chr4_-_185776854 0.09 ENST00000511703.1
RP11-701P16.5
RP11-701P16.5
chr9_-_88874519 0.09 ENST00000376001.3
ENST00000339137.3
C9orf153
chromosome 9 open reading frame 153
chr16_+_28763108 0.09 ENST00000357796.3
ENST00000550983.1
NPIPB9
nuclear pore complex interacting protein family, member B9
chr8_+_101349823 0.09 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr10_-_99030395 0.09 ENST00000355366.5
ENST00000371027.1
ARHGAP19
Rho GTPase activating protein 19
chr12_-_100656134 0.09 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr21_+_17791838 0.09 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr20_-_14318248 0.09 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr22_-_29107919 0.09 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr3_-_178865747 0.09 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr4_+_86525299 0.09 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr12_-_118796910 0.09 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chrX_+_100663243 0.09 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr12_-_118796971 0.09 ENST00000542902.1
TAOK3
TAO kinase 3
chr17_-_6915646 0.08 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr6_-_18265050 0.08 ENST00000397239.3
DEK
DEK oncogene
chr12_-_80328949 0.08 ENST00000450142.2
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr14_+_23025534 0.08 ENST00000557595.1
AE000662.92
Uncharacterized protein
chr1_+_53480598 0.08 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr14_+_64970427 0.08 ENST00000553583.1
ZBTB1
zinc finger and BTB domain containing 1
chr5_+_32710736 0.08 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr14_+_85994943 0.08 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chrX_-_63425561 0.08 ENST00000374869.3
ENST00000330258.3
AMER1
APC membrane recruitment protein 1
chr12_-_6602955 0.08 ENST00000543703.1
MRPL51
mitochondrial ribosomal protein L51
chr13_-_48669204 0.08 ENST00000417167.1
MED4
mediator complex subunit 4
chr8_+_26240414 0.08 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr7_-_64451414 0.08 ENST00000282869.6
ZNF117
zinc finger protein 117
chr17_-_62499334 0.08 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr14_+_56078695 0.08 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr5_+_153418466 0.08 ENST00000522782.1
ENST00000439768.2
ENST00000436816.1
ENST00000322602.5
ENST00000522177.1
ENST00000520899.1
MFAP3
microfibrillar-associated protein 3
chr4_-_157892167 0.08 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr1_+_174933899 0.08 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr1_-_151148492 0.08 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chr1_-_161337662 0.08 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr8_-_36636676 0.07 ENST00000524132.1
ENST00000519451.1
RP11-962G15.1
RP11-962G15.1
chr9_+_2159850 0.07 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_46926048 0.07 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr4_-_168155577 0.07 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr11_-_75017734 0.07 ENST00000532525.1
ARRB1
arrestin, beta 1
chr12_-_110511424 0.07 ENST00000548191.1
C12orf76
chromosome 12 open reading frame 76
chr11_+_86502085 0.07 ENST00000527521.1
PRSS23
protease, serine, 23
chr10_+_105036909 0.07 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr16_+_21623958 0.07 ENST00000568826.1
METTL9
methyltransferase like 9
chr4_+_95174445 0.07 ENST00000509418.1
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr8_-_123706338 0.07 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr3_-_121740969 0.07 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr8_-_10987745 0.07 ENST00000400102.3
AF131215.5
AF131215.5
chr2_+_46926326 0.07 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr10_+_97759848 0.07 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr2_-_101034070 0.07 ENST00000264249.3
CHST10
carbohydrate sulfotransferase 10
chr14_+_63671105 0.07 ENST00000316754.3
RHOJ
ras homolog family member J
chr5_+_34685805 0.07 ENST00000508315.1
RAI14
retinoic acid induced 14
chr4_-_153456153 0.07 ENST00000603548.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr11_+_827248 0.07 ENST00000527089.1
ENST00000530183.1
EFCAB4A
EF-hand calcium binding domain 4A
chr17_-_57970074 0.07 ENST00000346141.6
TUBD1
tubulin, delta 1
chr3_+_178866199 0.07 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr6_+_123110302 0.07 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chrX_+_123097014 0.07 ENST00000394478.1
STAG2
stromal antigen 2
chr19_-_54106751 0.07 ENST00000600193.1
CTB-167G5.5
Uncharacterized protein
chr1_-_193075180 0.07 ENST00000367440.3
GLRX2
glutaredoxin 2
chr5_-_111091948 0.07 ENST00000447165.2
NREP
neuronal regeneration related protein
chr5_+_32711419 0.07 ENST00000265074.8
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_+_172502244 0.07 ENST00000610051.1
SUCO
SUN domain containing ossification factor
chr5_+_43603229 0.07 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr12_+_50144381 0.06 ENST00000552370.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr13_+_20532848 0.06 ENST00000382874.2
ZMYM2
zinc finger, MYM-type 2
chrX_+_52841228 0.06 ENST00000351072.1
ENST00000425386.1
ENST00000375503.3
XAGE5
X antigen family, member 5
chr12_-_74686314 0.06 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr19_+_18451439 0.06 ENST00000597431.2
PGPEP1
pyroglutamyl-peptidase I
chrX_+_49832231 0.06 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr18_-_21852143 0.06 ENST00000399443.3
OSBPL1A
oxysterol binding protein-like 1A
chr12_-_323689 0.06 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr10_-_76868931 0.06 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13
dual specificity phosphatase 13
chr4_-_74486347 0.06 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr6_+_123110465 0.06 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr6_-_11779014 0.06 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr18_-_24237339 0.06 ENST00000580191.1
KCTD1
potassium channel tetramerization domain containing 1
chr12_+_62860581 0.06 ENST00000393632.2
ENST00000393630.3
ENST00000280379.6
ENST00000546600.1
ENST00000552738.1
ENST00000393629.2
ENST00000552115.1
MON2
MON2 homolog (S. cerevisiae)
chr1_+_104198377 0.06 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr6_-_11779174 0.06 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr1_-_203151933 0.06 ENST00000404436.2
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_48866517 0.06 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr7_-_74221288 0.06 ENST00000451013.2
GTF2IRD2
GTF2I repeat domain containing 2
chr3_-_46786245 0.06 ENST00000442359.2
PRSS45
protease, serine, 45
chr19_+_18451391 0.06 ENST00000269919.6
ENST00000604499.2
ENST00000595066.1
ENST00000252813.5
PGPEP1
pyroglutamyl-peptidase I
chr2_+_120517717 0.06 ENST00000420482.1
ENST00000488279.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr14_-_92506371 0.06 ENST00000267622.4
TRIP11
thyroid hormone receptor interactor 11
chr4_-_157892055 0.06 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr4_-_113558014 0.06 ENST00000503172.1
ENST00000505019.1
ENST00000309071.5
C4orf21
chromosome 4 open reading frame 21
chr1_-_82726817 0.06 ENST00000420549.1
RP11-147G16.1
RP11-147G16.1
chr15_-_90358048 0.06 ENST00000300060.6
ENST00000560137.1
ANPEP
alanyl (membrane) aminopeptidase
chr10_-_112678904 0.06 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBIP1
BBSome interacting protein 1
chr3_+_10068095 0.06 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr13_+_20532900 0.06 ENST00000382871.2
ZMYM2
zinc finger, MYM-type 2
chr6_-_110964453 0.06 ENST00000413605.2
CDK19
cyclin-dependent kinase 19
chr4_-_74486217 0.06 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr17_-_56082455 0.06 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr1_-_151813033 0.05 ENST00000454109.1
C2CD4D
C2 calcium-dependent domain containing 4D
chr10_-_38146965 0.05 ENST00000395873.3
ENST00000357328.4
ENST00000395874.2
ZNF248
zinc finger protein 248
chr2_+_48796120 0.05 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr1_-_197169672 0.05 ENST00000367405.4
ZBTB41
zinc finger and BTB domain containing 41
chr10_+_115511434 0.05 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr3_-_18466026 0.05 ENST00000417717.2
SATB1
SATB homeobox 1
chr6_+_26365443 0.05 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr1_+_111682058 0.05 ENST00000545121.1
CEPT1
choline/ethanolamine phosphotransferase 1
chr4_-_89978299 0.05 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A
family with sequence similarity 13, member A
chr11_-_19263145 0.05 ENST00000532666.1
ENST00000527884.1
E2F8
E2F transcription factor 8
chr11_-_96076334 0.05 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr4_+_96012585 0.05 ENST00000502683.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr10_-_24911746 0.05 ENST00000320481.6
ARHGAP21
Rho GTPase activating protein 21
chr14_-_57735528 0.05 ENST00000340918.7
ENST00000413566.2
EXOC5
exocyst complex component 5
chr5_-_96518907 0.05 ENST00000508447.1
ENST00000283109.3
RIOK2
RIO kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.2 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.1 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events