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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IRF7

Z-value: 1.79

Motif logo

Transcription factors associated with IRF7

Gene Symbol Gene ID Gene Info
ENSG00000185507.15 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615570_615728-0.088.8e-01Click!

Activity profile of IRF7 motif

Sorted Z-values of IRF7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_55237484 2.26 ENST00000394609.2
reticulon 4
chr4_+_103790462 1.95 ENST00000503643.1
CDGSH iron sulfur domain 2
chr2_+_7017796 1.30 ENST00000382040.3
radical S-adenosyl methionine domain containing 2
chr19_+_39759154 1.14 ENST00000331982.5
interferon, lambda 2
chr3_-_28390298 1.05 ENST00000457172.1
5-azacytidine induced 2
chr2_-_188419078 1.00 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr3_+_178865887 1.00 ENST00000477735.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr2_-_152118352 0.98 ENST00000331426.5
RNA binding motif protein 43
chr15_+_35270552 0.97 ENST00000391457.2
HCG37415; PRO1914; Uncharacterized protein
chr17_-_57229155 0.94 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr5_+_133707252 0.93 ENST00000506787.1
ENST00000507277.1
ubiquitin-conjugating enzyme E2B
chr14_+_73563735 0.93 ENST00000532192.1
RNA binding motif protein 25
chr3_-_28390120 0.92 ENST00000334100.6
5-azacytidine induced 2
chr14_-_35182994 0.92 ENST00000341223.3
cofilin 2 (muscle)
chr11_-_112034780 0.88 ENST00000524595.1
interleukin 18 (interferon-gamma-inducing factor)
chr6_+_63921351 0.83 ENST00000370659.1
FK506 binding protein 1C
chr17_-_46623441 0.83 ENST00000330070.4
homeobox B2
chrX_-_119693745 0.82 ENST00000371323.2
cullin 4B
chrX_-_20236970 0.82 ENST00000379548.4
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chrX_-_20237059 0.81 ENST00000457145.1
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr16_+_53412368 0.78 ENST00000565189.1
RP11-44F14.2
chr4_+_75174180 0.76 ENST00000413830.1
epithelial mitogen
chr4_+_41614909 0.76 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr4_-_169401628 0.75 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr3_-_28390415 0.75 ENST00000414162.1
ENST00000420543.2
5-azacytidine induced 2
chr5_+_147691979 0.73 ENST00000274565.4
serine peptidase inhibitor, Kazal type 7 (putative)
chr16_-_69385681 0.70 ENST00000288025.3
transmembrane emp24 protein transport domain containing 6
chr14_+_32546145 0.69 ENST00000556611.1
ENST00000539826.2
Rho GTPase activating protein 5
chr15_+_63354769 0.68 ENST00000558910.1
tropomyosin 1 (alpha)
chr19_+_39786962 0.66 ENST00000333625.2
interferon, lambda 1
chr4_+_159131630 0.65 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
transmembrane protein 144
chr8_+_97657531 0.64 ENST00000519900.1
ENST00000517742.1
carboxypeptidase Q
chr9_-_21995249 0.63 ENST00000494262.1
cyclin-dependent kinase inhibitor 2A
chr4_-_36245561 0.63 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_120687335 0.61 ENST00000544261.1
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr4_-_48683188 0.61 ENST00000505759.1
FRY-like
chr1_-_150693318 0.61 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMA domain containing 1
chr1_-_149459549 0.60 ENST00000369175.3
family with sequence similarity 72, member C
chr2_-_55277692 0.60 ENST00000394611.2
reticulon 4
chr8_-_82608409 0.60 ENST00000518568.1
solute carrier family 10, member 5
chr1_+_150245099 0.60 ENST00000369099.3
chromosome 1 open reading frame 54
chr5_+_133706865 0.60 ENST00000265339.2
ubiquitin-conjugating enzyme E2B
chr1_+_63833261 0.59 ENST00000371108.4
ALG6, alpha-1,3-glucosyltransferase
chr1_+_104068562 0.58 ENST00000423855.2
RNA-binding region (RNP1, RRM) containing 3
chr4_+_74301880 0.58 ENST00000395792.2
ENST00000226359.2
alpha-fetoprotein
chr15_+_96876340 0.58 ENST00000453270.2
nuclear receptor subfamily 2, group F, member 2
chr2_-_188419200 0.57 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr4_-_14889791 0.56 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
long intergenic non-protein coding RNA 504
chr22_-_29107919 0.56 ENST00000434810.1
ENST00000456369.1
checkpoint kinase 2
chr2_+_29341037 0.56 ENST00000449202.1
CAP-GLY domain containing linker protein family, member 4
chr14_-_35183755 0.55 ENST00000555765.1
cofilin 2 (muscle)
chr10_+_91061712 0.55 ENST00000371826.3
interferon-induced protein with tetratricopeptide repeats 2
chr15_+_96875657 0.54 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr12_+_19358192 0.53 ENST00000538305.1
pleckstrin homology domain containing, family A member 5
chr3_+_180319918 0.53 ENST00000296015.4
ENST00000491380.1
ENST00000412756.2
ENST00000382584.4
tetratricopeptide repeat domain 14
chr5_+_180682720 0.53 ENST00000599439.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr17_-_62499334 0.53 ENST00000579996.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr1_+_104068312 0.53 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNA-binding region (RNP1, RRM) containing 3
chr18_+_61575200 0.52 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr20_+_58571419 0.52 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
cadherin 26
chr2_-_163099546 0.52 ENST00000447386.1
fibroblast activation protein, alpha
chr6_+_151358048 0.52 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr12_-_10282742 0.51 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chr14_-_54908043 0.51 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
cornichon family AMPA receptor auxiliary protein 1
chr14_-_64108125 0.51 ENST00000267522.3
WD repeat domain 89
chr8_-_30002179 0.50 ENST00000320542.3
membrane bound O-acyltransferase domain containing 4
chr6_+_116782527 0.50 ENST00000368606.3
ENST00000368605.1
family with sequence similarity 26, member F
chr22_-_22641542 0.48 ENST00000606654.1
LL22NC03-2H8.5
chr4_+_41614720 0.48 ENST00000509277.1
LIM and calponin homology domains 1
chr16_-_79634595 0.48 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr16_-_67260901 0.47 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr8_+_27632047 0.46 ENST00000397418.2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr5_-_55777586 0.46 ENST00000506836.1
Uncharacterized protein
chr14_-_35099377 0.46 ENST00000362031.4
sorting nexin 6
chr5_+_67588312 0.46 ENST00000519025.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr10_-_18944123 0.46 ENST00000606425.1
Uncharacterized protein
chr4_-_169239921 0.45 ENST00000514995.1
ENST00000393743.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr4_+_159131596 0.45 ENST00000512481.1
transmembrane protein 144
chr1_-_115301235 0.44 ENST00000525878.1
cold shock domain containing E1, RNA-binding
chr12_+_102091400 0.44 ENST00000229266.3
ENST00000549872.1
choline phosphotransferase 1
chr1_-_111506562 0.44 ENST00000485275.2
ENST00000369763.4
ligand dependent nuclear receptor interacting factor 1
chr14_+_32547434 0.44 ENST00000556191.1
ENST00000554090.1
Rho GTPase activating protein 5
chr8_+_9009296 0.44 ENST00000521718.1
Uncharacterized protein
chr7_+_37723450 0.44 ENST00000447769.1
G protein-coupled receptor 141
chr12_+_97300995 0.43 ENST00000266742.4
ENST00000429527.2
ENST00000554226.1
ENST00000557478.1
ENST00000557092.1
ENST00000411739.2
ENST00000553609.1
neural precursor cell expressed, developmentally down-regulated 1
chr7_-_111424506 0.42 ENST00000450156.1
ENST00000494651.2
dedicator of cytokinesis 4
chr6_-_45345597 0.42 ENST00000371460.1
ENST00000371459.1
suppressor of Ty 3 homolog (S. cerevisiae)
chr1_+_78470530 0.42 ENST00000370763.5
DnaJ (Hsp40) homolog, subfamily B, member 4
chr6_+_26440700 0.42 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr14_-_24977457 0.42 ENST00000250378.3
ENST00000206446.4
chymase 1, mast cell
chr1_-_108743471 0.42 ENST00000569674.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr6_+_32811861 0.42 ENST00000453426.1
TAP1 and PSMB8 antisense RNA 1
chr8_+_26150628 0.41 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr17_-_33905521 0.41 ENST00000225873.4
peroxisomal biogenesis factor 12
chr11_+_9406169 0.41 ENST00000379719.3
ENST00000527431.1
importin 7
chr7_+_23221438 0.41 ENST00000258742.5
nucleoporin like 2
chr10_+_94608245 0.41 ENST00000443748.2
ENST00000260762.6
exocyst complex component 6
chr7_-_111428957 0.41 ENST00000417165.1
dedicator of cytokinesis 4
chr7_-_76955563 0.41 ENST00000441833.2
gamma-secretase activating protein
chr12_-_102591604 0.40 ENST00000329406.4
pro-melanin-concentrating hormone
chr12_-_10022735 0.40 ENST00000228438.2
C-type lectin domain family 2, member B
chr5_-_82373260 0.40 ENST00000502346.1
transmembrane protein 167A
chr4_+_142557717 0.40 ENST00000320650.4
ENST00000296545.7
interleukin 15
chr4_-_103748271 0.40 ENST00000343106.5
ubiquitin-conjugating enzyme E2D 3
chr2_-_40006289 0.40 ENST00000260619.6
ENST00000454352.2
THUMP domain containing 2
chr10_+_94590910 0.39 ENST00000371547.4
exocyst complex component 6
chr16_-_14726576 0.39 ENST00000562896.1
poly(A)-specific ribonuclease
chr15_+_45923776 0.38 ENST00000565227.1
ENST00000563296.1
sulfide quinone reductase-like (yeast)
chr17_-_46667594 0.38 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
homeobox B3
chr12_+_19358228 0.38 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr7_+_75931861 0.37 ENST00000248553.6
heat shock 27kDa protein 1
chr3_+_159706537 0.37 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr11_+_28131821 0.37 ENST00000379199.2
ENST00000303459.6
methyltransferase like 15
chr11_-_28129656 0.37 ENST00000263181.6
kinesin family member 18A
chr8_+_90914073 0.37 ENST00000297438.2
oxidative stress induced growth inhibitor family member 2
chr11_-_93583697 0.37 ENST00000409977.1
V-set and transmembrane domain containing 5
chrX_+_78003204 0.37 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr6_+_134273321 0.37 ENST00000457715.1
TBP-like 1
chr11_+_77532233 0.37 ENST00000525409.1
adipogenesis associated, Mth938 domain containing
chr4_-_111120334 0.37 ENST00000503885.1
ELOVL fatty acid elongase 6
chr11_-_5537920 0.36 ENST00000380184.1
ubiquilin-like
chr8_+_42873548 0.36 ENST00000533338.1
ENST00000534420.1
hook microtubule-tethering protein 3
Uncharacterized protein
chr2_+_210444748 0.36 ENST00000392194.1
microtubule-associated protein 2
chr12_+_80838126 0.36 ENST00000266688.5
protein tyrosine phosphatase, receptor type, Q
chr11_-_111794446 0.36 ENST00000527950.1
crystallin, alpha B
chr3_-_171489085 0.36 ENST00000418087.1
phospholipase D1, phosphatidylcholine-specific
chr14_-_36990061 0.35 ENST00000546983.1
NK2 homeobox 1
chr7_-_92146729 0.35 ENST00000541751.1
peroxisomal biogenesis factor 1
chr8_+_39770803 0.35 ENST00000518237.1
indoleamine 2,3-dioxygenase 1
chr14_+_32546274 0.34 ENST00000396582.2
Rho GTPase activating protein 5
chr9_-_72374848 0.34 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
protein prenyltransferase alpha subunit repeat containing 1
chr18_+_29027696 0.34 ENST00000257189.4
desmoglein 3
chr3_-_197026152 0.34 ENST00000419354.1
discs, large homolog 1 (Drosophila)
chr1_+_25664408 0.34 ENST00000374358.4
transmembrane protein 50A
chr1_+_158901329 0.34 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
pyrin and HIN domain family, member 1
chr10_-_92681033 0.34 ENST00000371697.3
ankyrin repeat domain 1 (cardiac muscle)
chrX_+_119737806 0.34 ENST00000371317.5
malignant T cell amplified sequence 1
chr7_-_84121858 0.34 ENST00000448879.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr4_-_87281224 0.33 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr2_-_152146385 0.33 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr13_-_30424821 0.33 ENST00000380680.4
ubiquitin-like 3
chr6_-_101329191 0.33 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
activating signal cointegrator 1 complex subunit 3
chr15_+_31196080 0.33 ENST00000561607.1
ENST00000565466.1
FANCD2/FANCI-associated nuclease 1
chrX_-_34675391 0.33 ENST00000275954.3
transmembrane protein 47
chr11_-_47736896 0.33 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
ATP/GTP binding protein-like 2
chr1_-_150693305 0.32 ENST00000368987.1
HORMA domain containing 1
chr16_-_21289627 0.32 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr17_-_67057047 0.32 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ATP-binding cassette, sub-family A (ABC1), member 9
chrX_+_22050546 0.32 ENST00000379374.4
phosphate regulating endopeptidase homolog, X-linked
chr1_-_226496898 0.32 ENST00000481685.1
lin-9 homolog (C. elegans)
chr7_-_84122033 0.32 ENST00000424555.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr9_-_32526184 0.32 ENST00000545044.1
ENST00000379868.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr13_+_109248500 0.31 ENST00000356711.2
myosin XVI
chr2_+_169312350 0.31 ENST00000305747.6
ceramide synthase 6
chr1_+_92632542 0.31 ENST00000409154.4
ENST00000370378.4
KIAA1107
chr4_+_78804393 0.31 ENST00000502384.1
mitochondrial ribosomal protein L1
chr15_+_38964048 0.31 ENST00000560203.1
ENST00000557946.1
RP11-275I4.2
chr1_+_112016414 0.31 ENST00000343534.5
ENST00000369718.3
chromosome 1 open reading frame 162
chr3_+_154797781 0.31 ENST00000382989.3
membrane metallo-endopeptidase
chr1_+_144989309 0.30 ENST00000596396.1
Uncharacterized protein
chr5_+_34915444 0.30 ENST00000336767.5
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr12_-_49319265 0.30 ENST00000552878.1
ENST00000453172.2
FK506 binding protein 11, 19 kDa
chr10_+_94352956 0.30 ENST00000260731.3
kinesin family member 11
chr7_-_138794081 0.30 ENST00000464606.1
zinc finger CCCH-type, antiviral 1
chr14_-_61748550 0.30 ENST00000555868.1
transmembrane protein 30B
chr10_+_22614547 0.30 ENST00000416820.1
BMI1 polycomb ring finger oncogene
chr13_+_20532848 0.30 ENST00000382874.2
zinc finger, MYM-type 2
chr1_-_100715372 0.30 ENST00000370131.3
ENST00000370132.4
dihydrolipoamide branched chain transacylase E2
chr6_-_56492816 0.30 ENST00000522360.1
dystonin
chr13_-_86373536 0.30 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr19_+_49977818 0.30 ENST00000594009.1
ENST00000595510.1
fms-related tyrosine kinase 3 ligand
chr7_-_112579869 0.29 ENST00000297145.4
chromosome 7 open reading frame 60
chr15_+_78832747 0.29 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr4_-_39034542 0.29 ENST00000344606.6
transmembrane protein 156
chr14_-_23288930 0.29 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr4_+_144434584 0.29 ENST00000283131.3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr19_-_3761673 0.29 ENST00000316757.3
amyloid beta (A4) precursor protein-binding, family A, member 3
chr5_+_82373317 0.29 ENST00000282268.3
ENST00000338635.6
X-ray repair complementing defective repair in Chinese hamster cells 4
chr2_-_128785619 0.29 ENST00000450957.1
Sin3A-associated protein, 130kDa
chr9_-_32526299 0.28 ENST00000379882.1
ENST00000379883.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_+_99771418 0.28 ENST00000393473.2
ENST00000393477.3
ENST00000393474.3
ENST00000340066.1
ENST00000393471.2
ENST00000449211.1
ENST00000434566.1
ENST00000410042.1
lipoyltransferase 1
39S ribosomal protein L30, mitochondrial
chr4_-_139163491 0.28 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr15_+_49715449 0.28 ENST00000560979.1
fibroblast growth factor 7
chr2_+_163175394 0.28 ENST00000446271.1
ENST00000429691.2
grancalcin, EF-hand calcium binding protein
chr10_-_65028817 0.28 ENST00000542921.1
jumonji domain containing 1C
chr5_+_118668846 0.28 ENST00000513374.1
tumor necrosis factor, alpha-induced protein 8
chrX_+_77166172 0.28 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr10_-_65028938 0.28 ENST00000402544.1
jumonji domain containing 1C
chr3_-_168865522 0.28 ENST00000464456.1
MDS1 and EVI1 complex locus
chr22_+_20905422 0.28 ENST00000424287.1
ENST00000423862.1
mediator complex subunit 15
chr14_-_69262947 0.28 ENST00000557086.1
ZFP36 ring finger protein-like 1
chr18_+_32173276 0.28 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr6_-_30709980 0.27 ENST00000416018.1
ENST00000445853.1
ENST00000413165.1
ENST00000418160.1
flotillin 1
chr19_-_53445819 0.27 ENST00000549216.1
zinc finger protein 816
chr6_+_87865262 0.27 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr15_+_45003675 0.27 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
beta-2-microglobulin
chr8_+_109455830 0.27 ENST00000524143.1
ER membrane protein complex subunit 2
chr5_+_82373379 0.27 ENST00000396027.4
ENST00000511817.1
X-ray repair complementing defective repair in Chinese hamster cells 4
chr2_-_88285309 0.27 ENST00000420840.2
RANBP2-like and GRIP domain containing 2
chr5_+_131892603 0.27 ENST00000378823.3
ENST00000265335.6
RAD50 homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.4 3.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 1.6 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 0.9 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.3 0.8 GO:0045062 extrathymic T cell selection(GO:0045062)
0.3 1.1 GO:0009956 radial pattern formation(GO:0009956)
0.3 0.8 GO:0021569 rhombomere 3 development(GO:0021569)
0.3 2.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 1.0 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 0.7 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.9 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.2 1.3 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.2 0.6 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 0.5 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.2 0.6 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.7 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.6 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.1 0.4 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.6 GO:0021546 rhombomere development(GO:0021546)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.1 0.5 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.6 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 1.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.4 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.3 GO:0036269 swimming behavior(GO:0036269)
0.1 0.7 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.7 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.3 GO:0050822 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.3 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.7 GO:1902571 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 0.2 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.6 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.7 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 0.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.5 GO:0070475 rRNA base methylation(GO:0070475)
0.1 1.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.2 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.2 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.2 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.2 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.2 GO:1902724 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.4 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.2 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
0.0 1.9 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.3 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.9 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.5 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 1.9 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.1 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463) negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.0 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.8 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:2000834 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.7 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.6 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.9 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.6 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.0 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0048284 organelle fusion(GO:0048284)
0.0 0.3 GO:0021549 cerebellum development(GO:0021549)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.0 0.1 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885) regulation of osteoclast proliferation(GO:0090289)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.3 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.1 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.3 GO:0015866 ADP transport(GO:0015866)
0.0 1.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.4 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0071789 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.5 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.4 GO:0032463 tubulin complex assembly(GO:0007021) negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.3 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441) kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.2 1.5 GO:0033503 HULC complex(GO:0033503)
0.2 0.6 GO:0031213 RSF complex(GO:0031213)
0.1 0.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.7 GO:0097422 tubular endosome(GO:0097422)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 2.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.6 GO:0031906 late endosome lumen(GO:0031906)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.1 0.3 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 1.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.7 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.6 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.3 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.3 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.3 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.5 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 0.4 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.4 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.7 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.8 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.3 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.6 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 2.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.5 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.3 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.0 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.3 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.6 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.4 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 1.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 1.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.9 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.1 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0009384 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 3.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.0 PID IL27 PATHWAY IL27-mediated signaling events
0.0 3.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.6 PID ATM PATHWAY ATM pathway
0.0 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.0 PID INSULIN PATHWAY Insulin Pathway
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.6 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 1.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 2.8 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.6 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs