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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ISL1

Z-value: 0.63

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Transcription factors associated with ISL1

Gene Symbol Gene ID Gene Info
ISL1
ENSG00000016082.10 ISL LIM homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISL1hg19_v2_chr5_+_50679506_506795060.582.3e-01Click!

Activity profile of ISL1 motif

Sorted Z-values of ISL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_24621546 0.41 ENST00000566108.1
CTD-2540M10.1
CTD-2540M10.1
chr5_+_137203541 0.29 ENST00000421631.2
MYOT
myotilin
chr2_-_175711133 0.28 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr16_+_47496023 0.28 ENST00000567200.1
PHKB
phosphorylase kinase, beta
chr17_-_7760457 0.26 ENST00000576384.1
LSMD1
LSM domain containing 1
chr17_+_63096903 0.25 ENST00000582940.1
RP11-160O5.1
RP11-160O5.1
chr3_-_100551141 0.24 ENST00000478235.1
ENST00000471901.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr17_-_39123144 0.22 ENST00000355612.2
KRT39
keratin 39
chr14_+_21566980 0.22 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr11_-_7904464 0.21 ENST00000502624.2
ENST00000527565.1
RP11-35J10.5
RP11-35J10.5
chr20_-_45530365 0.21 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr14_+_62462541 0.20 ENST00000430451.2
SYT16
synaptotagmin XVI
chr2_+_149402009 0.20 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr13_-_50020554 0.19 ENST00000400396.1
AL136218.1
Sarcoma antigen NY-SAR-79; Uncharacterized protein
chr5_+_137203557 0.18 ENST00000515645.1
MYOT
myotilin
chr12_-_96793142 0.18 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr12_-_42631529 0.18 ENST00000548917.1
YAF2
YY1 associated factor 2
chr2_+_47454054 0.17 ENST00000426892.1
AC106869.2
AC106869.2
chr20_-_25320367 0.16 ENST00000450393.1
ENST00000491682.1
ABHD12
abhydrolase domain containing 12
chr5_+_137203465 0.16 ENST00000239926.4
MYOT
myotilin
chr3_-_186262166 0.15 ENST00000307944.5
CRYGS
crystallin, gamma S
chr4_+_8201091 0.14 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr4_-_186877481 0.14 ENST00000444781.1
ENST00000432655.1
SORBS2
sorbin and SH3 domain containing 2
chr2_+_207804278 0.14 ENST00000272852.3
CPO
carboxypeptidase O
chr17_+_6918354 0.13 ENST00000552775.1
C17orf49
chromosome 17 open reading frame 49
chr5_-_94417562 0.13 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr5_-_159766528 0.13 ENST00000505287.2
CCNJL
cyclin J-like
chr13_+_78315348 0.13 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr14_+_32963433 0.13 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chr10_-_17659357 0.13 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr5_-_56778635 0.13 ENST00000423391.1
ACTBL2
actin, beta-like 2
chr4_-_168155169 0.13 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr21_+_17792672 0.12 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr14_+_93357749 0.12 ENST00000557689.1
RP11-862G15.1
RP11-862G15.1
chr10_-_17659234 0.12 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr16_+_3493611 0.12 ENST00000407558.4
ENST00000572169.1
ENST00000572757.1
ENST00000573593.1
ENST00000570372.1
ENST00000424546.2
ENST00000575733.1
ENST00000573201.1
ENST00000574950.1
ENST00000573580.1
ENST00000608722.1
NAA60
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
N-alpha-acetyltransferase 60
chr12_-_57037284 0.11 ENST00000551570.1
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr15_-_100258029 0.11 ENST00000378904.2
DKFZP779J2370
DKFZP779J2370
chrX_+_10031499 0.11 ENST00000454666.1
WWC3
WWC family member 3
chr15_+_76352178 0.11 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr11_-_115127611 0.11 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr1_+_156024525 0.11 ENST00000368305.4
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr4_+_71384257 0.11 ENST00000339336.4
AMTN
amelotin
chr8_-_25281747 0.11 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr18_-_19283649 0.11 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr12_+_79357815 0.10 ENST00000547046.1
SYT1
synaptotagmin I
chr2_-_208030295 0.10 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr5_+_140593509 0.10 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr4_-_77328458 0.10 ENST00000388914.3
ENST00000434846.2
CCDC158
coiled-coil domain containing 158
chr8_-_116681686 0.10 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chr12_+_50144381 0.10 ENST00000552370.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr7_+_138915102 0.10 ENST00000486663.1
UBN2
ubinuclein 2
chr1_-_9953295 0.10 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr4_-_186877806 0.10 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr9_-_113100088 0.10 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr6_-_131211534 0.10 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr17_-_33885117 0.10 ENST00000415846.3
SLFN14
schlafen family member 14
chr5_-_94417339 0.10 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr5_+_32710736 0.10 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr12_+_9066472 0.10 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr9_+_136325089 0.10 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1
calcium channel flower domain containing 1
chr19_-_12889226 0.09 ENST00000589400.1
ENST00000590839.1
ENST00000592079.1
HOOK2
hook microtubule-tethering protein 2
chr22_-_43355858 0.09 ENST00000402229.1
ENST00000407585.1
ENST00000453079.1
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr6_-_130031358 0.09 ENST00000368149.2
ARHGAP18
Rho GTPase activating protein 18
chr11_-_107729287 0.09 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr7_-_44580861 0.08 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1
NPC1-like 1
chr4_-_186734275 0.08 ENST00000456060.1
SORBS2
sorbin and SH3 domain containing 2
chr4_+_4861385 0.08 ENST00000382723.4
MSX1
msh homeobox 1
chr18_-_52989525 0.08 ENST00000457482.3
TCF4
transcription factor 4
chr10_-_75118611 0.08 ENST00000355577.3
ENST00000394865.1
ENST00000310715.3
ENST00000401621.2
TTC18
tetratricopeptide repeat domain 18
chr1_+_156024552 0.08 ENST00000368304.5
ENST00000368302.3
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr18_-_52989217 0.07 ENST00000570287.2
TCF4
transcription factor 4
chr11_-_111649074 0.07 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr5_+_135468516 0.07 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chr5_+_140248518 0.07 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr11_+_7618413 0.07 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_227050079 0.07 ENST00000423838.1
AC068138.1
AC068138.1
chr1_-_79472365 0.07 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr6_+_90272488 0.07 ENST00000485637.1
ENST00000522705.1
ANKRD6
ankyrin repeat domain 6
chr2_-_224467093 0.07 ENST00000305409.2
SCG2
secretogranin II
chr7_+_129932974 0.07 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4
carboxypeptidase A4
chr9_+_131084815 0.07 ENST00000300452.3
ENST00000609948.1
COQ4
coenzyme Q4
chr9_-_134585221 0.07 ENST00000372190.3
ENST00000427994.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr9_+_131084846 0.07 ENST00000608951.1
COQ4
coenzyme Q4
chr4_-_87281196 0.06 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr10_+_123923205 0.06 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr16_-_23464459 0.06 ENST00000307149.5
COG7
component of oligomeric golgi complex 7
chr14_-_21566731 0.06 ENST00000360947.3
ZNF219
zinc finger protein 219
chr2_+_166152283 0.06 ENST00000375427.2
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr14_-_77495007 0.06 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr17_-_15501932 0.06 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr5_-_138211051 0.06 ENST00000518785.1
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr19_-_22806764 0.06 ENST00000598042.1
AC011516.2
AC011516.2
chr1_-_95391315 0.06 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chrX_+_49832231 0.06 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr6_+_15401075 0.06 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr18_-_21977748 0.06 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr12_-_94673956 0.06 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr8_+_70404996 0.06 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr4_+_113970772 0.06 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr4_+_169418255 0.06 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr2_-_220034745 0.06 ENST00000455516.2
ENST00000396775.3
ENST00000295738.7
SLC23A3
solute carrier family 23, member 3
chrX_-_100129128 0.06 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr13_+_78315295 0.06 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr6_-_116575226 0.06 ENST00000420283.1
TSPYL4
TSPY-like 4
chr3_+_121774202 0.06 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr5_+_140772381 0.06 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr11_-_125351481 0.05 ENST00000577924.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr7_+_20686946 0.05 ENST00000443026.2
ENST00000406935.1
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr5_-_102455801 0.05 ENST00000508629.1
ENST00000399004.2
GIN1
gypsy retrotransposon integrase 1
chr17_+_1933404 0.05 ENST00000263083.6
ENST00000571418.1
DPH1
diphthamide biosynthesis 1
chrX_-_110655306 0.05 ENST00000371993.2
DCX
doublecortin
chr11_-_66496430 0.05 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr11_-_107729887 0.05 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr18_-_53177984 0.05 ENST00000543082.1
TCF4
transcription factor 4
chr6_+_90272339 0.05 ENST00000522779.1
ANKRD6
ankyrin repeat domain 6
chr19_+_3178736 0.05 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr9_+_128510454 0.05 ENST00000491787.3
ENST00000447726.2
PBX3
pre-B-cell leukemia homeobox 3
chrX_-_102983417 0.05 ENST00000372617.4
GLRA4
glycine receptor, alpha 4
chr7_+_103969104 0.05 ENST00000424859.1
ENST00000535008.1
ENST00000401970.2
ENST00000543266.1
LHFPL3
lipoma HMGIC fusion partner-like 3
chr6_+_90272027 0.05 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr1_-_154842741 0.05 ENST00000271915.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr12_-_51418549 0.05 ENST00000548150.1
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr12_-_11139511 0.04 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr11_-_64660916 0.04 ENST00000413053.1
MIR194-2
microRNA 194-2
chr6_+_139135648 0.04 ENST00000541398.1
ECT2L
epithelial cell transforming sequence 2 oncogene-like
chr8_+_21911054 0.04 ENST00000519850.1
ENST00000381470.3
DMTN
dematin actin binding protein
chr17_-_39023462 0.04 ENST00000251643.4
KRT12
keratin 12
chr18_+_55018044 0.04 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chrX_-_118986911 0.04 ENST00000276201.2
ENST00000345865.2
UPF3B
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr3_+_57875711 0.04 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr17_-_40729681 0.04 ENST00000590760.1
ENST00000587209.1
ENST00000393795.3
ENST00000253789.5
PSMC3IP
PSMC3 interacting protein
chr1_+_197170592 0.04 ENST00000535699.1
CRB1
crumbs homolog 1 (Drosophila)
chrX_-_102941596 0.04 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
MORF4L2
mortality factor 4 like 2
chr8_-_99955042 0.04 ENST00000519420.1
STK3
serine/threonine kinase 3
chr4_+_104346194 0.04 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chr14_+_20811766 0.04 ENST00000250416.5
ENST00000527915.1
PARP2
poly (ADP-ribose) polymerase 2
chr15_+_59279851 0.04 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111
ring finger protein 111
chrX_-_92928557 0.04 ENST00000373079.3
ENST00000475430.2
NAP1L3
nucleosome assembly protein 1-like 3
chr6_+_31515337 0.04 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chrX_-_15619076 0.04 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr7_+_99724317 0.04 ENST00000398075.2
ENST00000421390.1
MBLAC1
metallo-beta-lactamase domain containing 1
chr5_-_138210977 0.04 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr5_+_102200948 0.04 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr4_+_159727272 0.04 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chrX_-_110513703 0.04 ENST00000324068.1
CAPN6
calpain 6
chr1_-_108231101 0.04 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr16_+_20775358 0.04 ENST00000440284.2
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr11_-_46113756 0.04 ENST00000531959.1
PHF21A
PHD finger protein 21A
chr4_-_68829226 0.04 ENST00000396188.2
TMPRSS11A
transmembrane protease, serine 11A
chr2_-_217560248 0.04 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr4_+_71384300 0.04 ENST00000504451.1
AMTN
amelotin
chr14_+_62585332 0.04 ENST00000554895.1
LINC00643
long intergenic non-protein coding RNA 643
chr14_+_37126765 0.04 ENST00000402703.2
PAX9
paired box 9
chr4_-_174451370 0.04 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr4_-_68829144 0.03 ENST00000508048.1
TMPRSS11A
transmembrane protease, serine 11A
chr6_+_31707725 0.03 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
MSH5
mutS homolog 5
chr10_+_114710425 0.03 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr9_-_96108696 0.03 ENST00000375419.1
C9orf129
chromosome 9 open reading frame 129
chr3_+_130279178 0.03 ENST00000358511.6
ENST00000453409.2
COL6A6
collagen, type VI, alpha 6
chr5_-_88180342 0.03 ENST00000502983.1
MEF2C
myocyte enhancer factor 2C
chr18_-_46784778 0.03 ENST00000582399.1
DYM
dymeclin
chr7_+_16793160 0.03 ENST00000262067.4
TSPAN13
tetraspanin 13
chr17_-_2615031 0.03 ENST00000576885.1
ENST00000574426.2
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr12_-_6484715 0.03 ENST00000228916.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chrX_+_65382433 0.03 ENST00000374727.3
HEPH
hephaestin
chr11_+_22694123 0.03 ENST00000534801.1
GAS2
growth arrest-specific 2
chr16_+_20775024 0.03 ENST00000289416.5
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr16_-_4664860 0.03 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chrX_-_117107680 0.03 ENST00000447671.2
ENST00000262820.3
KLHL13
kelch-like family member 13
chr19_-_50143452 0.03 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr12_-_30887948 0.03 ENST00000433722.2
CAPRIN2
caprin family member 2
chr6_+_155537771 0.03 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr5_-_41794313 0.03 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr2_+_211421262 0.03 ENST00000233072.5
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr9_+_27109133 0.03 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr3_-_121740969 0.03 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr17_-_47045949 0.03 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chr1_+_200011711 0.03 ENST00000544748.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr12_-_52761262 0.03 ENST00000257901.3
KRT85
keratin 85
chr6_-_100912785 0.03 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr7_+_13141097 0.03 ENST00000411542.1
AC011288.2
AC011288.2
chr7_-_35734176 0.03 ENST00000413517.1
ENST00000438224.1
HERPUD2
HERPUD family member 2
chr2_+_172543919 0.03 ENST00000452242.1
ENST00000340296.4
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr17_-_21156578 0.03 ENST00000399011.2
ENST00000468196.1
C17orf103
chromosome 17 open reading frame 103
chr12_+_93096619 0.03 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chrX_+_114874727 0.03 ENST00000543070.1
PLS3
plastin 3
chr1_+_113217043 0.03 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr17_+_66521936 0.03 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chrX_+_65382381 0.03 ENST00000519389.1
HEPH
hephaestin
chr11_-_107729504 0.03 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr11_+_22688150 0.03 ENST00000454584.2
GAS2
growth arrest-specific 2
chr10_-_18940501 0.03 ENST00000377304.4
NSUN6
NOP2/Sun domain family, member 6
chr12_-_10251603 0.03 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chrX_-_117119243 0.02 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chrX_-_100129320 0.02 ENST00000372966.3
NOX1
NADPH oxidase 1
chr10_-_95241951 0.02 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr1_+_113217073 0.02 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr11_-_26744908 0.02 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr6_-_32498046 0.02 ENST00000374975.3
HLA-DRB5
major histocompatibility complex, class II, DR beta 5

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.0 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.0 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.0 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.0 0.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.0 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.0 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors