Project

NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for KLF1

Z-value: 1.01

Motif logo

logo of

Transcription factors associated with KLF1

Gene Symbol Gene ID Gene Info
KLF1
ENSG00000105610.4 Kruppel like factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF1hg19_v2_chr19_-_12997995_129980210.562.5e-01Click!

Activity profile of KLF1 motif

Sorted Z-values of KLF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_38171681 1.96 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr7_+_22766766 1.58 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr17_+_38171614 1.31 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr12_-_49581152 0.84 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr5_+_159895275 0.76 ENST00000517927.1
MIR146A
microRNA 146a
chr22_-_39639021 0.73 ENST00000455790.1
PDGFB
platelet-derived growth factor beta polypeptide
chr8_-_42065187 0.60 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT
plasminogen activator, tissue
chr6_+_43968306 0.58 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr22_-_30642728 0.57 ENST00000403987.3
LIF
leukemia inhibitory factor
chr16_+_89989687 0.56 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
TUBB3
Tubulin beta-3 chain
chr4_-_82965397 0.52 ENST00000512716.1
ENST00000514050.1
ENST00000512343.1
ENST00000510780.1
ENST00000508294.1
RASGEF1B
RP11-689K5.3
RasGEF domain family, member 1B
RP11-689K5.3
chr16_-_31161380 0.51 ENST00000569305.1
ENST00000418068.2
ENST00000268281.4
PRSS36
protease, serine, 36
chr17_+_38673270 0.45 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr15_+_45923776 0.43 ENST00000565227.1
ENST00000563296.1
SQRDL
sulfide quinone reductase-like (yeast)
chr1_+_11866270 0.42 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr19_+_54960790 0.42 ENST00000443957.1
LENG8
leukocyte receptor cluster (LRC) member 8
chr13_-_74708372 0.37 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr12_-_56693758 0.36 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
CS
citrate synthase
chr2_-_26205340 0.35 ENST00000264712.3
KIF3C
kinesin family member 3C
chr2_+_74212073 0.34 ENST00000441217.1
AC073046.25
AC073046.25
chr6_+_106546808 0.34 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr1_-_26680570 0.34 ENST00000475866.2
AIM1L
absent in melanoma 1-like
chr17_+_7210921 0.34 ENST00000573542.1
EIF5A
eukaryotic translation initiation factor 5A
chr6_-_3227877 0.33 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chr6_-_38607628 0.32 ENST00000498633.1
BTBD9
BTB (POZ) domain containing 9
chr22_+_38071615 0.32 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr1_+_35225339 0.31 ENST00000339480.1
GJB4
gap junction protein, beta 4, 30.3kDa
chr10_+_104155450 0.31 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr10_+_120967072 0.30 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr17_-_79520135 0.30 ENST00000541246.1
ENST00000544302.1
C17orf70
chromosome 17 open reading frame 70
chr12_+_120502441 0.30 ENST00000446727.2
CCDC64
coiled-coil domain containing 64
chr17_+_7210852 0.29 ENST00000576930.1
EIF5A
eukaryotic translation initiation factor 5A
chr16_+_31483451 0.29 ENST00000565360.1
ENST00000361773.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr20_+_44035200 0.29 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_-_26205550 0.28 ENST00000405914.1
KIF3C
kinesin family member 3C
chr9_+_74764278 0.28 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr17_-_39553844 0.28 ENST00000251645.2
KRT31
keratin 31
chr5_-_115910630 0.27 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr22_+_31477296 0.27 ENST00000426927.1
ENST00000440425.1
ENST00000358743.1
ENST00000347557.2
ENST00000333137.7
SMTN
smoothelin
chr16_+_50313426 0.26 ENST00000569265.1
ADCY7
adenylate cyclase 7
chr10_+_17272608 0.26 ENST00000421459.2
VIM
vimentin
chr15_-_44069513 0.26 ENST00000433927.1
ELL3
elongation factor RNA polymerase II-like 3
chr12_+_56498312 0.25 ENST00000552766.1
PA2G4
proliferation-associated 2G4, 38kDa
chr19_+_39687596 0.24 ENST00000339852.4
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr14_+_32414059 0.23 ENST00000553330.1
RP11-187E13.1
Uncharacterized protein
chr6_+_106534192 0.23 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr9_+_74764340 0.23 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr20_+_44035847 0.22 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_-_153573965 0.21 ENST00000448428.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr1_+_11866207 0.21 ENST00000312413.6
ENST00000346436.6
CLCN6
chloride channel, voltage-sensitive 6
chr16_+_67312049 0.21 ENST00000565899.1
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr17_-_39661947 0.21 ENST00000590425.1
KRT13
keratin 13
chr16_-_8962200 0.20 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr16_-_31146961 0.20 ENST00000567531.1
PRSS8
protease, serine, 8
chr16_-_8962853 0.20 ENST00000565287.1
ENST00000311052.5
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr17_-_27188984 0.20 ENST00000582320.2
MIR144
microRNA 451b
chr16_-_30125177 0.20 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr17_-_1389228 0.19 ENST00000438665.2
MYO1C
myosin IC
chr1_+_209929446 0.19 ENST00000479796.1
TRAF3IP3
TRAF3 interacting protein 3
chr7_-_944631 0.19 ENST00000453175.2
ADAP1
ArfGAP with dual PH domains 1
chr16_-_30134266 0.19 ENST00000484663.1
ENST00000478356.1
MAPK3
mitogen-activated protein kinase 3
chr15_+_67390920 0.19 ENST00000559092.1
ENST00000560175.1
SMAD3
SMAD family member 3
chr15_-_60690163 0.19 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr17_+_1633755 0.19 ENST00000545662.1
WDR81
WD repeat domain 81
chr3_+_106959552 0.19 ENST00000473550.1
LINC00883
long intergenic non-protein coding RNA 883
chr16_+_30969055 0.18 ENST00000452917.1
SETD1A
SET domain containing 1A
chr19_-_42916499 0.18 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr19_+_41699103 0.18 ENST00000597754.1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr3_+_142342240 0.18 ENST00000497199.1
PLS1
plastin 1
chr20_-_62710832 0.18 ENST00000395042.1
RGS19
regulator of G-protein signaling 19
chr8_-_123793048 0.18 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr16_-_58033762 0.18 ENST00000299237.2
ZNF319
zinc finger protein 319
chr18_-_5540471 0.18 ENST00000581833.1
ENST00000544123.1
ENST00000342933.3
ENST00000400111.3
ENST00000585142.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr12_-_56694083 0.18 ENST00000552688.1
ENST00000548041.1
ENST00000551137.1
ENST00000551968.1
ENST00000542324.2
ENST00000546930.1
ENST00000549221.1
ENST00000550159.1
ENST00000550734.1
CS
citrate synthase
chr11_-_64014379 0.17 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr22_+_37959647 0.17 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr17_-_6917755 0.17 ENST00000593646.1
AC040977.1
Uncharacterized protein
chr1_+_55505184 0.16 ENST00000302118.5
PCSK9
proprotein convertase subtilisin/kexin type 9
chr6_-_31697563 0.16 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr20_+_44034804 0.16 ENST00000357275.2
ENST00000372720.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr1_+_43148059 0.16 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr1_+_161195835 0.16 ENST00000545897.1
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr5_+_71403061 0.16 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr18_+_55712915 0.16 ENST00000592846.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr3_+_238456 0.16 ENST00000427688.1
CHL1
cell adhesion molecule L1-like
chr1_-_24126023 0.15 ENST00000429356.1
GALE
UDP-galactose-4-epimerase
chr12_-_125398602 0.15 ENST00000541272.1
ENST00000535131.1
UBC
ubiquitin C
chr1_+_161195781 0.15 ENST00000367988.3
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr17_-_1389419 0.15 ENST00000575158.1
MYO1C
myosin IC
chr6_+_33589161 0.15 ENST00000605930.1
ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chr19_+_36120009 0.15 ENST00000589871.1
RBM42
RNA binding motif protein 42
chr9_-_38069208 0.15 ENST00000377707.3
ENST00000377700.4
SHB
Src homology 2 domain containing adaptor protein B
chr12_-_108154705 0.15 ENST00000547188.1
PRDM4
PR domain containing 4
chr5_-_115910091 0.15 ENST00000257414.8
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr19_+_35629702 0.15 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr16_+_58033450 0.14 ENST00000561743.1
USB1
U6 snRNA biogenesis 1
chr19_+_8455200 0.14 ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr9_-_35111570 0.14 ENST00000378561.1
ENST00000603301.1
FAM214B
family with sequence similarity 214, member B
chr1_-_43833628 0.14 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr12_+_51632666 0.14 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr5_-_168006591 0.14 ENST00000239231.6
PANK3
pantothenate kinase 3
chr9_+_112887772 0.14 ENST00000259318.7
AKAP2
A kinase (PRKA) anchor protein 2
chr3_-_50383096 0.14 ENST00000442887.1
ENST00000360165.3
ZMYND10
zinc finger, MYND-type containing 10
chr11_+_64009072 0.14 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr16_+_30075463 0.14 ENST00000562168.1
ENST00000569545.1
ALDOA
aldolase A, fructose-bisphosphate
chr2_+_85132749 0.14 ENST00000233143.4
TMSB10
thymosin beta 10
chr8_-_145018080 0.14 ENST00000354589.3
PLEC
plectin
chrX_+_47077632 0.13 ENST00000457458.2
CDK16
cyclin-dependent kinase 16
chr19_-_51522955 0.13 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr15_-_72521017 0.13 ENST00000561609.1
PKM
pyruvate kinase, muscle
chr16_+_30075783 0.13 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr19_+_7599792 0.13 ENST00000600942.1
ENST00000593924.1
PNPLA6
patatin-like phospholipase domain containing 6
chr17_+_7210294 0.13 ENST00000336452.7
EIF5A
eukaryotic translation initiation factor 5A
chr16_+_56225248 0.13 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr15_+_44069276 0.13 ENST00000381359.1
SERF2
small EDRK-rich factor 2
chr6_-_31697255 0.13 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_-_153508460 0.13 ENST00000462776.2
S100A6
S100 calcium binding protein A6
chr16_+_31483374 0.13 ENST00000394863.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr3_-_186080012 0.13 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr5_+_89770696 0.13 ENST00000504930.1
ENST00000514483.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr20_+_35974532 0.13 ENST00000373578.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr5_+_140501581 0.13 ENST00000194152.1
PCDHB4
protocadherin beta 4
chr17_-_46703826 0.13 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr2_-_219151984 0.13 ENST00000444000.1
ENST00000418569.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr9_-_35111420 0.13 ENST00000378557.1
FAM214B
family with sequence similarity 214, member B
chr14_-_64971288 0.13 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chrX_-_153151586 0.13 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
L1CAM
L1 cell adhesion molecule
chr4_+_39699664 0.13 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
UBE2K
ubiquitin-conjugating enzyme E2K
chr11_-_119252359 0.13 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr16_+_30075595 0.13 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr5_+_141016508 0.13 ENST00000444782.1
ENST00000521367.1
ENST00000297164.3
RELL2
RELT-like 2
chr12_-_58146048 0.12 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4
cyclin-dependent kinase 4
chr19_+_46850320 0.12 ENST00000391919.1
PPP5C
protein phosphatase 5, catalytic subunit
chr14_+_101292445 0.12 ENST00000429159.2
ENST00000520714.1
ENST00000522771.2
ENST00000424076.3
ENST00000423456.1
ENST00000521404.1
ENST00000556736.1
ENST00000451743.2
ENST00000398518.2
ENST00000554639.1
ENST00000452120.2
ENST00000519709.1
ENST00000412736.2
MEG3
maternally expressed 3 (non-protein coding)
chr19_+_46850251 0.12 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr1_-_39395165 0.12 ENST00000372985.3
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr19_-_10946871 0.12 ENST00000589638.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr1_-_113249678 0.12 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr19_-_51523275 0.12 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr1_-_154155675 0.12 ENST00000330188.9
ENST00000341485.5
TPM3
tropomyosin 3
chr2_-_85637459 0.12 ENST00000409921.1
CAPG
capping protein (actin filament), gelsolin-like
chr19_-_18654293 0.12 ENST00000597547.1
ENST00000222308.4
ENST00000544835.3
ENST00000610101.1
ENST00000597960.3
ENST00000608443.1
FKBP8
FK506 binding protein 8, 38kDa
chr19_-_51523412 0.12 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr17_-_66287310 0.12 ENST00000582867.1
SLC16A6
solute carrier family 16, member 6
chr15_+_75074410 0.12 ENST00000439220.2
CSK
c-src tyrosine kinase
chr6_-_31763276 0.12 ENST00000440048.1
VARS
valyl-tRNA synthetase
chr6_+_30850862 0.12 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr10_+_94608245 0.12 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr11_+_61248583 0.12 ENST00000432063.2
ENST00000338608.2
PPP1R32
protein phosphatase 1, regulatory subunit 32
chr2_+_54684327 0.12 ENST00000389980.3
SPTBN1
spectrin, beta, non-erythrocytic 1
chr8_+_120428546 0.12 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr19_-_10047219 0.11 ENST00000264833.4
OLFM2
olfactomedin 2
chr20_-_43743790 0.11 ENST00000307971.4
ENST00000372789.4
WFDC5
WAP four-disulfide core domain 5
chr3_-_127542021 0.11 ENST00000434178.2
MGLL
monoglyceride lipase
chr1_+_203765437 0.11 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr6_-_43596899 0.11 ENST00000307126.5
ENST00000452781.1
GTPBP2
GTP binding protein 2
chr1_-_159893507 0.11 ENST00000368096.1
TAGLN2
transgelin 2
chr7_+_73245193 0.11 ENST00000340958.2
CLDN4
claudin 4
chr20_+_60878005 0.11 ENST00000253003.2
ADRM1
adhesion regulating molecule 1
chr16_-_30596818 0.11 ENST00000567773.1
ZNF785
zinc finger protein 785
chr19_+_1104048 0.11 ENST00000593032.1
ENST00000588919.1
GPX4
glutathione peroxidase 4
chr1_-_1009683 0.11 ENST00000453464.2
RNF223
ring finger protein 223
chr19_-_47349395 0.11 ENST00000597020.1
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
chr22_-_20138302 0.11 ENST00000540078.1
ENST00000439765.2
AC006547.14
uncharacterized protein LOC388849
chr19_+_41698927 0.11 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr19_+_47616682 0.11 ENST00000594526.1
SAE1
SUMO1 activating enzyme subunit 1
chr7_-_1600433 0.11 ENST00000431208.1
TMEM184A
transmembrane protein 184A
chr1_-_243326612 0.11 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr1_+_43148625 0.11 ENST00000436427.1
YBX1
Y box binding protein 1
chr16_+_30078811 0.11 ENST00000564688.1
ALDOA
aldolase A, fructose-bisphosphate
chr17_-_7518145 0.11 ENST00000250113.7
ENST00000571597.1
FXR2
fragile X mental retardation, autosomal homolog 2
chr1_-_113249734 0.11 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C
chr17_-_47755338 0.11 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
SPOP
speckle-type POZ protein
chr1_+_209929494 0.10 ENST00000367026.3
TRAF3IP3
TRAF3 interacting protein 3
chr17_-_39942322 0.10 ENST00000449889.1
ENST00000465293.1
JUP
junction plakoglobin
chr12_+_122326630 0.10 ENST00000541212.1
ENST00000340175.5
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr6_+_83903061 0.10 ENST00000369724.4
ENST00000539997.1
RWDD2A
RWD domain containing 2A
chr17_+_38599693 0.10 ENST00000542955.1
ENST00000269593.4
IGFBP4
insulin-like growth factor binding protein 4
chr1_-_94147385 0.10 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr11_-_65625014 0.10 ENST00000534784.1
CFL1
cofilin 1 (non-muscle)
chr19_+_36119975 0.10 ENST00000589559.1
ENST00000360475.4
RBM42
RNA binding motif protein 42
chr1_-_113249948 0.10 ENST00000339083.7
ENST00000369642.3
RHOC
ras homolog family member C
chr5_-_172756506 0.10 ENST00000265087.4
STC2
stanniocalcin 2
chr17_-_39023462 0.10 ENST00000251643.4
KRT12
keratin 12
chrX_+_47078069 0.10 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
CDK16
cyclin-dependent kinase 16
chr19_+_38664224 0.10 ENST00000601054.1
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr10_+_104678032 0.10 ENST00000369878.4
ENST00000369875.3
CNNM2
cyclin M2
chr6_-_30654977 0.10 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr20_-_31124186 0.10 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr12_-_125398850 0.10 ENST00000535859.1
ENST00000546271.1
ENST00000540700.1
ENST00000546120.1
UBC
ubiquitin C
chr9_-_100954910 0.10 ENST00000375077.4
CORO2A
coronin, actin binding protein, 2A
chr19_+_50919056 0.10 ENST00000599632.1
CTD-2545M3.6
CTD-2545M3.6
chr13_+_24553933 0.10 ENST00000424834.2
ENST00000439928.2
SPATA13
RP11-309I15.1
spermatogenesis associated 13
RP11-309I15.1
chr4_-_926161 0.10 ENST00000511163.1
GAK
cyclin G associated kinase
chr3_+_49711391 0.10 ENST00000296456.5
ENST00000449966.1
APEH
acylaminoacyl-peptide hydrolase
chr4_-_165305086 0.10 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr9_-_35732362 0.10 ENST00000314888.9
ENST00000540444.1
TLN1
talin 1
chr1_+_44399466 0.10 ENST00000498139.2
ENST00000491846.1
ARTN
artemin
chr1_-_6526192 0.10 ENST00000377782.3
ENST00000351959.5
ENST00000356876.3
TNFRSF25
tumor necrosis factor receptor superfamily, member 25
chr5_-_141016382 0.10 ENST00000523088.1
ENST00000305264.3
HDAC3
histone deacetylase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.3 3.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.6 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 0.7 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 0.5 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.6 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.7 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.1 GO:0061196 fungiform papilla development(GO:0061196)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.2 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0044145 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.3 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.6 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.1 GO:1902871 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.2 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.2 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.0 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0090649 rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.2 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.8 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.2 0.6 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 0.5 GO:0008892 guanine deaminase activity(GO:0008892)
0.2 1.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.2 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.5 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 2.8 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis